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Hire Dr. Hela B.

Tunisia

USD 35 /hr

PhD biologist and genetic analyst / genetic variant interpretation ( NGS, CGH ARRAY, CYTOGENETIC. MOLECULAR GENETICS)

Profile Summary

PhD biologist with experience in genetic variant interpretation, cytogenetics and molecular diagnostics, previously contributing to rare disease analysis and reporting at Centogene. skilled in NGS data review, CNV interpretation, and ACMG classification as well as scientific writing . I'am currently an independant scientific consultant.

Subject Matter Expertise

• ★ Human Biology
• ★ Molecular Pathology
• ☆ Precision Medicine
• ☆ Clinical Laboratory Science
• ☆ Clinical Pathology
• ☆ Health Informatics
• ☆ Medical Sciences

Services

• Writing

Writing Technical Writing

Work Experience

Genetic analyst

Centogene (Germany)

May 2025 - September 2025

Post doc researcher

cytogenetic Laboratory of sousse

June 2016 - June 2018

Education

PhD in biology and biotechnology

ISBM University of Monastir

September 2010 - May 2016

PhD (Biology and biotechnology )

University of Monastir

September 2010 - May 2016

Certifications

• PhD in biology and biotechnology

  University of Monastir- Tunisia

  May 2016 - Present

Publications

JOURNAL ARTICLE

Anomalies in Human Sex Determination: Usefulness of a Combined Cytogenetic Approach to Characterize an Additional Case with Xp Functional Disomy Associated with 46,XY Gonadal Dysgenesis @article{Khouloud_2023, title={Anomalies in Human Sex Determination: Usefulness of a Combined Cytogenetic Approach to Characterize an Additional Case with Xp Functional Disomy Associated with 46,XY Gonadal Dysgenesis}, volume={15}, ISSN={1308-5735}, url={http://dx.doi.org/10.4274/jcrpe.galenos.2022.2022-3-15}, DOI={10.4274/jcrpe.galenos.2022.2022-3-15}, number={1}, journal={Journal of Clinical Research in Pediatric Endocrinology}, publisher={Galenos Yayinevi}, author={Khouloud, Rjiba and Slimani, Wafa and Gaddas, Meriem and hassine, Ikbel Hadj and Jelloul, Afef and Khelifa, Hela Ben and Amri, Fethi El and Zaouali, Monia and Mcelreavey, Kenneth and Saad, Ali and Mougou-Zerelli, Soumaya}, year={2023}, month=feb, pages={25–34} } . Journal of Clinical Research in Pediatric Endocrinology.

Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development @article{Rjiba_2023, title={Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development}, volume={21}, ISSN={1477-7827}, url={http://dx.doi.org/10.1186/s12958-022-01045-7}, DOI={10.1186/s12958-022-01045-7}, number={1}, journal={Reproductive Biology and Endocrinology}, publisher={Springer Science and Business Media LLC}, author={Rjiba, Khouloud and Mougou-Zerelli, Soumaya and Hamida, Imen hadj and Saad, Ghada and Khadija, Bochra and Jelloul, Afef and Slimani, Wafa and Hasni, Yosra and Dimassi, Sarra and khelifa, Hela Ben and Sallem, Amira and Kammoun, Molka and Abdallah, Hamza Hadj and Gribaa, Moez and Bignon-Topalovic, Joelle and Chelly, Sami and Khairi, Hédi and Bibi, Mohamed and Kacem, Maha and Saad, Ali and Bashamboo, Anu and McElreavey, Kenneth}, year={2023}, month=jan } . Reproductive Biology and Endocrinology.

Clinical and molecular findings in nine new cases of tetrasomy 18p syndrome: FISH and array CGH characterization @article{Slimani_2019, title={Clinical and molecular findings in nine new cases of tetrasomy 18p syndrome: FISH and array CGH characterization}, volume={12}, ISSN={1755-8166}, url={http://dx.doi.org/10.1186/s13039-019-0414-8}, DOI={10.1186/s13039-019-0414-8}, number={1}, journal={Molecular Cytogenetics}, publisher={Springer Science and Business Media LLC}, author={Slimani, Wafa and Ben Khelifa, Hela and Dimassi, Sarra and Chioukh, Fatma-Zohra and Jelloul, Afef and Kammoun, Molka and Hannachi, Hanene and Bouslah, Sarra and Jammali, Nesrine and Sanlaville, Damien and Saad, Ali and Mougou-Zerelli, Soumaya}, year={2019}, month=feb } . Molecular Cytogenetics.

Genomic Microarray in Intellectual Disability: The Usefulness of Existing Systems in the Interpretation of Copy Number Variation @article{Soyah_2016, title={Genomic Microarray in Intellectual Disability: The Usefulness of Existing Systems in the Interpretation of Copy Number Variation}, volume={06}, ISSN={2146-460X}, url={http://dx.doi.org/10.1055/s-0036-1588027}, DOI={10.1055/s-0036-1588027}, number={02}, journal={Journal of Pediatric Genetics}, publisher={Mathematical Modelling and Numerical Simulation with Applications}, author={Soyah, Najla and Labalme, Audrey and Guilbert, Helene and Sanlaville, Damien and Saad, Ali and Mougou-Zerelli, Soumaya and Ben Khelifa, Hela}, year={2016}, month=sep, pages={084–091} } . Journal of Pediatric Genetics.

Microarray Analysis of 8p23.1 Deletion in New Patients with Atypical Phenotypical Traits @article{Kammoun_2015, title={Microarray Analysis of 8p23.1 Deletion in New Patients with Atypical Phenotypical Traits}, volume={04}, ISSN={2146-460X}, url={http://dx.doi.org/10.1055/s-0035-1565269}, DOI={10.1055/s-0035-1565269}, number={04}, journal={Journal of Pediatric Genetics}, publisher={Necmettin Erbakan University Press}, author={Kammoun, Molka and Hannachi, Hanene and Soyah, Najla and Hammami, Saber and Elghezal, Hatem and Sanlaville, Damien and Saad, Ali and Mougou-Zerelli, Soumaya and Khelifa, Hela}, year={2015}, month=oct, pages={187–193} } . Journal of Pediatric Genetics.

Xp22.3 interstitial deletion: A recognizable chromosomal abnormality encompassing VCX3A and STS genes in a patient with X-linked ichthyosis and mental retardation @article{Ben_Khelifa_2013, title={Xp22.3 interstitial deletion: A recognizable chromosomal abnormality encompassing VCX3A and STS genes in a patient with X-linked ichthyosis and mental retardation}, volume={527}, ISSN={0378-1119}, url={http://dx.doi.org/10.1016/j.gene.2013.06.018}, DOI={10.1016/j.gene.2013.06.018}, number={2}, journal={Gene}, publisher={Elsevier BV}, author={Ben Khelifa, Hela and Soyah, Najla and Ben-Abdallah-Bouhjar, Inesse and Gritly, Ryma and Sanlaville, Damien and Elghezal, Hatem and Saad, Ali and Mougou-Zerelli, Soumaya}, year={2013}, month=sep, pages={578–583} } . Gene.

Phenotype and Micro-array characterization of duplication 11q22.1-q25 and review of the literature @article{Ben_Abdallah_Bouhjar_2013, title={Phenotype and Micro-array characterization of duplication 11q22.1-q25 and review of the literature}, volume={519}, ISSN={0378-1119}, url={http://dx.doi.org/10.1016/j.gene.2013.01.017}, DOI={10.1016/j.gene.2013.01.017}, number={1}, journal={Gene}, publisher={Elsevier BV}, author={Ben-Abdallah-Bouhjar, Inesse and Mougou-Zerelli, Soumya and Hannachi, Hanene and Ben-Khelifa, Hela and Soyah, Najla and Labalme, Audrey and Sanlaville, Damien and Elghezal, Hatem and Saad, Ali}, year={2013}, month=apr, pages={135–141} } . Gene.

A Combination of Micronucleus Assay and Fluorescence In Situ Hybridization Analysis to Evaluate the Genotoxicity of Formaldehyde @article{Bouraoui_2012, title={A Combination of Micronucleus Assay and Fluorescence In Situ Hybridization Analysis to Evaluate the Genotoxicity of Formaldehyde}, volume={64}, ISSN={1432-0703}, url={http://dx.doi.org/10.1007/s00244-012-9828-6}, DOI={10.1007/s00244-012-9828-6}, number={2}, journal={Archives of Environmental Contamination and Toxicology}, publisher={Springer Science and Business Media LLC}, author={Bouraoui, Sana and Mougou, Soumaya and Brahem, Aicha and Tabka, Faten and Ben Khelifa, Hela and Harrabi, Imed and Mrizek, Najib and Elghezal, Hatem and Saad, Ali}, year={2012}, month=nov, pages={337–344} } . Archives of Environmental Contamination and Toxicology.

Cryptic Rearrangements in Idiopathic Intellectual Disability Diagnosed by Molecular Cytogenetic Analysis @article{Bouhjar_2012, title={Cryptic Rearrangements in Idiopathic Intellectual Disability Diagnosed by Molecular Cytogenetic Analysis}, volume={12}, ISSN={2456-6330}, url={http://dx.doi.org/10.31901/24566330.2012/12.03.05}, DOI={10.31901/24566330.2012/12.03.05}, number={03}, journal={INTERNATIONAL JOURNAL OF HUMAN GENETICS}, publisher={Kamla Raj Enterprises}, author={Bouhjar, Inesse Ben Abdallah}, year={2012}, month=jun } . INTERNATIONAL JOURNAL OF HUMAN GENETICS.

OTHER

Autism in patients with Williams-Beuren syndrome: A re-evaluation of 31 Tunisian patients’ phenotype @article{Mougou_Zerelli_2022, title={Autism in patients with Williams-Beuren syndrome: A re-evaluation of 31 Tunisian patients’ phenotype}, url={http://dx.doi.org/10.21203/rs.3.rs-2139963/v1}, DOI={10.21203/rs.3.rs-2139963/v1}, publisher={Research Square Platform LLC}, author={Mougou-Zerelli, Soumaya and Khelifi, Rim and Jelloul, Afef and Ajmi, Houda and Dimassi, Sarra and Slimani, Wafa and Soyeh, Najla and Rjiba, Khouloud and Dardour, Manel and Abdallah, Hamza Hadj and Dridi, Hend and Guedria, Asma and Kammoun, Molka and Khelifa, Hela Ben and Mkadem, Hayet and Guidara, Ines Hssairi and Hamida, Hayet Ben and Helel, Khaled Ben and Kharrat, Habib and Sboui, Essia and Naffeti, Elies and Gaddour, Naoufel and Maatouk, Faouzi and Ghezal, Hatem El and Saad, Ali and Nouira, Ons and Zouari, Afif}, year={2022}, month=oct } .

GENOTYPE-PHENOTYPE CORRELATIONS FOR THE LISSENCEPHALY SPECTRUM OF EIGHT CHILDREN @article{Hadj_Amor_2018, title={GENOTYPE-PHENOTYPE CORRELATIONS FOR THE LISSENCEPHALY SPECTRUM OF EIGHT CHILDREN}, url={http://dx.doi.org/10.26226/morressier.5b5f433cb56e9b005965b902}, DOI={10.26226/morressier.5b5f433cb56e9b005965b902}, publisher={Morressier}, author={Hadj Amor, Meriam}, year={2018}, month=oct } .