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★★★★★
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Hire Dr. Harshvardhan M.
Singapore

Expert in Analytical Methods Development and Formulation Development

Profile Summary
Subject Matter Expertise
Services
Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, General Proofreading & Editing
Research Meta-Research, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection
Consulting Scientific and Technical Consulting
Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Data Visualization, Text Mining & Analytics, Data Cleaning, Data Processing, Data Insights
Product Development Formulation, Deformulation, Stability/Shelf Life Testing, Product Evaluation, Product Validation, Manufacturing, Quality Assurance & Control (QA/QC), Concept Development, Reverse Engineering
Work Experience

Senior Research Fellow

National University of Singapore

August 2019 - Present

Postdoctoral Research Fellow

Fraunhofer-IME

February 2019 - July 2019

Junior Research Fellow

University of Delhi

August 2013 - April 2014

Education

PhD (Institut für Technische Chemie)

Leibniz Universität Hannover

October 2014 - September 2018

M. S. (Pharm.) (Pharmaceutical Biotechnology)

National Institute of Pharmaceutical Education and Research

June 2011 - May 2013

Bachelor of Pharmacy (Pharmacy)

Nirma University of Science and Technology Institute of Pharmacy

September 2007 - April 2011

Certifications
Publications
JOURNAL ARTICLE
Harshvardhan Modh, Dylan Leong, Kiran Dindhoria, Julia Malinovskaya, Selene Pirola, Bernd Wendt, Matthias Gerhard Wacker (2026). Shear Stress Modeling and Machine Learning for Nanomedicine Development: A Mechanistic Pathway to Pharmacokinetic Prediction . ACS Nano.
Harshvardhan Modh, Dylan Leong, Kiran Dindhoria, Julia Malinovskaya, Selene Pirola, Bernd Wendt, Matthias Gerhard Wacker (2026). Shear Stress Modeling and Machine Learning for Nanomedicine Development: A Mechanistic Pathway to Pharmacokinetic Prediction . ACS Nano.
Harshvardhan Modh, Namrata Dhakal, Ern Ern Saw, Kok Liang Dylan Leong, Phyo Darli Maw, Lyes Kahouadji, Matthias Gerhard Wacker (2026). Liposomal design and shear shielding of colloidal matrices control drug release . International Journal of Pharmaceutics.
Modh, H., Benetti, A.A., Badruddoza, A.Z., Yan, J., Panczyk, T., Shah, J., Pastorin, G., Wacker, M.G.(2026). A virtual factory for topical formulations based on molecular modeling and drug-polymer interaction studies . Drug Delivery and Translational Research. 16. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1844-1859.
Dhakal, N., Saw, E.E., Leong, K.L.D., Maw, P.D., Modh, H., Kahouadji, L., Wacker, M.G.(2026). Liposomal design and shear shielding of colloidal matrices control drug release . International Journal of Pharmaceutics. 699.
Harshvardhan Modh, Ayça Altay Benetti, Tomasz Panczyk, Abu Zayed Badruddoza, Jaymin Shah, Matthias Gerhard Wacker, Giorgia Pastorin (2025). Understanding the Structure-Release Relationships of Sepineo™: molecular dynamics, physico-chemical characterization, in vitro and ex vivo permeation . Journal of Drug Delivery Science and Technology.
Benetti, A.A., Modh, H., Panczyk, T., Badruddoza, A.Z., Shah, J., Wacker, M.G., Pastorin, G.(2025). Understanding the Structure-Release Relationships of Sepineo™: molecular dynamics, physico-chemical characterization, in vitro and ex vivo permeation . Journal of Drug Delivery Science and Technology. 109.
Carrera-Bravo, C., Zhou, T., Chu, T., Hang, J.W., Modh, H., Huang, C., Zhang, S., Hao, H., Cabada-García, M.J., Malleret, B., et al.(2025). Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile . Frontiers in Cellular and Infection Microbiology. 15.
Gan, K., Li, Z., Darli, P.M., Wong, T., Modh, H., Gottier, P., Halbherr, S., Wacker, M.G.(2024). Understanding the In Vitro-In Vivo Nexus: Advanced correlation models predict clinical performance of liposomal doxorubicin . International Journal of Pharmaceutics. 654.
Lim, X.C., Huang, C., Yatim, S.M.J.M., Chong, S.Y., Tan, S.H., Yang, X., Heldt, C.L., Pedersen, J., Talanker, M., Modh, H., et al.(2023). Temporal Changes in Extracellular Vesicle Hemostatic Protein Composition Predict Favourable Left Ventricular Remodeling after Acute Myocardial Infarction . International Journal of Molecular Sciences. 24. (1).
Mast, M.-P., Modh, H., Knoll, J., Fecioru, E., Wacker, M.G.(2021). An update to dialysis-based drug release testing—data analysis and validation using the pharma test dispersion releaser . Pharmaceutics. 13. (12).
Kovshova, T., Osipova, N., Alekseeva, A., Malinovskaya, J., Belov, A., Budko, A., Pavlova, G., Maksimenko, O., Nagpal, S., Braner, S., et al.(2021). Exploring the interplay between drug release and targeting of lipid-like polymer nanoparticles loaded with doxorubicin . Molecules. 26. (4).
Modh, H., Fang, D.J., Ou, Y.H., Yau, J.N.N., Kovshova, T., Nagpal, S., Knoll, J., Wallenwein, C.M., Maiti, K., Bhowmick, S., et al.(2021). Injectable drug delivery systems of doxorubicin revisited: In vitro-in vivo relationships using human clinical data . International Journal of Pharmaceutics. 608.
Hering, I., Eilebrecht, E., Parnham, M.J., Weiler, M., Günday-Türeli, N., Türeli, A.E., Modh, H., Heng, P.W.S., Böhmer, W., Schäfers, C., et al.(2021). Microparticle formulations alter the toxicity of fenofibrate to the zebrafish Danio rerio embryo . Aquatic Toxicology. 234.
Mast, M.-P., Modh, H., Champanhac, C., Wang, J.-W., Storm, G., Krämer, J., Mailänder, V., Pastorin, G., Wacker, M.G.(2021). Nanomedicine at the crossroads – A quick guide for IVIVC . Advanced Drug Delivery Reviews. 179.
Gao, G.F., Ashtikar, M., Kojima, R., Yoshida, T., Kaihara, M., Tajiri, T., Shanehsazzadeh, S., Modh, H., Wacker, M.G.(2021). Predicting drug release and degradation kinetics of long-acting microsphere formulations of tacrolimus for subcutaneous injection . Journal of Controlled Release. 329. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 372-384.
(2020). Predicting human pharmacokinetics of liposomal temoporfin using a hybrid in silico model . European Journal of Pharmaceutics and Biopharmaceutics.
Jablonka, L., Ashtikar, M., Gao, G.F., Thurn, M., Modh, H., Wang, J.-W., Preuß, A., Scheglmann, D., Albrecht, V., Röder, B., et al.(2020). Predicting human pharmacokinetics of liposomal temoporfin using a hybrid in silico model . European Journal of Pharmaceutics and Biopharmaceutics. 149. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 121-134.
Nagpal, S., Braner, S., Modh, H., Tan, A.X.X., Mast, M.-P., Chichakly, K., Albrecht, V., Wacker, M.G.(2020). A physiologically-based nanocarrier biopharmaceutics model to reverse-engineer the in vivo drug release . European Journal of Pharmaceutics and Biopharmaceutics. 153. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 257-272.
Harshvardhan Modh, Thomas Scheper, Johanna-Gabriela Walter (2018). Aptamer-Modified Magnetic Beads in Biosensing . Sensors.
(2018). Aptamer-Modified Magnetic Beads in Biosensing . Sensors.
Modh, H., Scheper, T., Walter, J.-G.(2018). Aptamer-modified magnetic beads in biosensing . Sensors Switzerland. 18. (4).
Modh, H., Witt, M., Urmann, K., Lavrentieva, A., Segal, E., Scheper, T., Walter, J.-G.(2017). Aptamer-based detection of adenosine triphosphate via qPCR . Talanta. 172. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 199-205.
Modh, H., Scheper, T., Walter, J.-G.(2017). Detection of ochratoxin A by aptamer-assisted real-time PCR-based assay (Apta-qPCR) . Engineering in Life Sciences. 17. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 923-930.
Modh, H.B., Bhadra, A.K., Patel, K.A., Chaudhary, R.K., Jain, N.K., Roy, I.(2016). Specific detection of tetanus toxoid using an aptamer-based matrix . Journal of Biotechnology. 238. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 15-21.
BOOK CHAPTER
Ma, Y., Zhang, J., Yuan, Y., Modh, H., Yang, Z.(2025). Combined therapy in cancer treatment . Drug Delivery to Tumors Recent Strategies and Techniques. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 89-108.
OTHER
Benetti, A.A., Modh, H., Panczyk, T., Badruddoza, A.Z., Shah, J., Wacker, M.G., Pastorin, G.(2024). Understanding the Structure-Release Relationships of Sepineotm . Ssrn.
Carrera-Bravo, C., Zhou, T., Hang, J.W., Modh, H., Huang, F., Malleret, B., Wacker, M.G., Wang, J.-W., Renia, L., Tan, K.S.W.(2023). Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile . Biorxiv.