Profile Details

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Hire Dr. Harish K.

India

USD 20 /hr

Drug Discovery Medicinal Chemist with more than 10 years experience in Pharmaceutical Industry and Academia

Profile Summary

Pharmaceutical Medicinal Chemist, Drug Discovery, Drug Design, Computer Aided Drug Design

Subject Matter Expertise

• ☆ Chemoinformatics
• ☆ Green Chemistry
• ☆ Computational Chemistry
• ☆ Biochemistry
• ☆ Antioxidants
• ☆ Pharmacy
• ☆ Pharmacy Education
• ☆ Clinical Pharmacy
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Medicinal Chemistry
• ☆ Drug Design
• ☆ Combinatorial Chemistry
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Drug Formulation
• ☆ Small Molecule Drug Development
• ☆ Drug Substance Characterization
• ☆ Bioanalytical Testing
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Drug-Drug Interactions
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ Drug Efficacy Testing
• ☆ In vitro Diagnostics
• ☆ In vitro Diagnostic Design
• ☆ Medical Education
• ☆ Continuing Medical Education (CME)
• ☆ Health Informatics
• ☆ Positron Emission Tomography (PET)
• ☆ Complementary & Alternative Medicine
• ☆ Herbal Medicine
• ☆ Traditional Medicine
• ☆ Ayurveda
• ☆ Drug Delivery Technologies
• ☆ Pharmaceutical Technology

Services

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing, Creative Writing, Newswriting, General Proofreading & Editing, Translation

Research Market Research, User Research, Meta-Research, Feasibility Study, Technology Scouting, Fact Checking, Gap Analysis, Scientific and Technical Research

Consulting Business Strategy Consulting, Scientific and Technical Consulting

Product Development Formulation, Stability/Shelf Life Testing

Work Experience

HOD and Associate Professor

DY Patil Deemed to be University School of Pharmacy

January 2022 - Present

Associate Professor and Researcher

School of Pharmacy, D Y Patil Deemed to be University, Navi Mumbai, India

January 2022 - Present

Assistant Professor

Oriental College of Pharmacy

December 2020 - January 2022

Assistant Professor

Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS University

April 2017 - July 2020

Assistant Professor

C. U. Shah College of Pharmacy, SNDT University

June 2016 - December 2016

Lecturer

Gahlot Institute of Pharmacy, Mumbai University

October 2008 - April 2011

Education

Ph.D.(Tech.)

Institute of Chemical Technology - India

April 2011 - December 2017

Certifications

• Registered Pharmacist

  Pharmacy council of India

  October 2006 - Present

Publications

JOURNAL ARTICLE

(2020). Studies on spectral characterization and solubility of hydroxypropyl β-cyclodextrin/iloperidone binary and ternary complexes using different auxiliary agents . Journal of Molecular Structure.

(2019). Molecular dynamic simulations on an inhibitor of anti-apoptotic Bcl-2 proteins for insights into its interaction mechanism for anti-cancer activity . Journal of Biomolecular Structure and Dynamics.

(2019). Tetrahydrocurcumin-loaded vaginal nanomicrobicide for prophylaxis of HIV/AIDS: in silico study, formulation development, and in vitro evaluation . Drug Delivery and Translational Research.

(2019). Evaluation of phytopolyphenols for their gp120-CD4 binding inhibitory properties by in silico molecular modelling & in vitro cell line studies . Current HIV Research.

Kundaikar, Harish, Khambete, Mihir, Raju, Archana, Lonkar, Sachin, Degani, Mariam, Ray, Mukti Kanta (2019). Design and synthesis of 5-(5-nitrothiophen-2-yl)-3-phenyl-4,5-dihydro-1H-pyrazole derivatives with improved solubility and potential antituberculosis activity . Chemical Biology & Drug Design.

Anantram, A., Janve, M., Degani, M., Singhal, R., Kundaikar, H.(2018). Homology modelling of human divalent metal transporter (DMT): Molecular docking and dynamic simulations for duodenal iron transport . Journal of Molecular Graphics and Modelling. 85. p. 145-152.

Khambete, M., Kundaikar, H., Raju, A., Lonkar, S., Degani, M., Ray, M.K.(2018). Design and synthesis of 5-(5-nitrothiophen-2-yl)-3-phenyl-4,5-dihydro-1H-pyrazole derivatives with improved solubility and potential antituberculosis activity . Chemical Biology and Drug Design.

Kundaikar, Harish, Anantram, Aarti, Janve, Madhura, Degani, Mariam, Singhal, Rekha (2018). Homology modelling of human divalent metal transporter (DMT): Molecular docking and dynamic simulations for duodenal iron transport . Journal of Molecular Graphics and Modelling.

Bulani, V.D., Kothavade, P.S., Kundaikar, H.S., Gawali, N.B., Chowdhury, A.A., Degani, M.S., Juvekar, A.R.(2016). Inclusion complex of ellagic acid with β-cyclodextrin: Characterization and in vitro anti-inflammatory evaluation . Journal of Molecular Structure. 1105. p. 308-315.

Bulani, Vipin D., Kothavade, Pankaj S., Kundaikar, Harish S., Gawali, Nitin B., Chowdhury, Amrita A., Degani, Mariam S., Juvekar, Archana R. (2016). Inclusion complex of ellagic acid with beta-cyclodextrin: Characterization and in vitro anti-inflammatory evaluation . Journal of Molecular Structure.

Bulani, Vipin D., Kothavade, Pankaj S., Nagmoti, Dnyaneshwar M., Kundaikar, Harish S., Degani, Mariam S., Juvekar, Archana R. (2015). Characterisation and anti-inflammatory evaluation of the inclusion complex of ellagic acid with hydroxypropyl-beta-cyclodextrin . Journal of Inclusion Phenomena and Macrocyclic Chemistry.

Kundaikar, H.S., Sancheti, J.S., Jain, P.D., Degani, M.S., Sathaye, S.(2015). Docking studies and pharmacological evaluation of antiepileptic activity of phytoconstituents . Medicinal Chemistry Research. 24. (8). p. 3296-3304.

Gangurde, A.B., Kundaikar, H.S., Javeer, S.D., Jaiswar, D.R., Degani, M.S., Amin, P.D.(2015). Enhanced solubility and dissolution of curcumin by a hydrophilic polymer solid dispersion and its insilico molecular modeling studies . Journal of Drug Delivery Science and Technology. 29. p. 226-237.

Bulani, V.D., Kothavade, P.S., Nagmoti, D.M., Kundaikar, H.S., Degani, M.S., Juvekar, A.R.(2015). Characterisation and anti-inflammatory evaluation of the inclusion complex of ellagic acid with hydroxypropyl-β-cyclodextrin . Journal of Inclusion Phenomena and Macrocyclic Chemistry. 82. (3). p. 361-372.

Avinash B. Gangurde, Harish S. Kundaikar, Sharadchandra D. Javeer, Divakar R. Jaiswar, Mariam S. Degani, Purnima D. Amin (2015). Enhanced solubility and dissolution of curcumin by a hydrophilic polymer solid dispersion and its insilico molecular modeling studies . Journal of Drug Delivery Science and Technology.

Kundaikar HS, Degani MS (2015). Insights into the Interaction Mechanism of Ligands with A42 Based on Molecular Dynamics Simulations and Mechanics: Implications of Role of Common Binding Site in Drug Design for Alzheimer's Disease . Chemical Biology & Drug Design.

Kundaikar, H.S., Degani, M.S.(2015). Insights into the Interaction Mechanism of Ligands with Aβ42 Based on Molecular Dynamics Simulations and Mechanics: Implications of Role of Common Binding Site in Drug Design for Alzheimer's Disease . Chemical Biology and Drug Design. 86. (4). p. 805-812.

Kundaikar, H.S., Agre, N.P., Degani, M.S.(2014). Pharmacophore based 3DQSAR of phenothiazines as specific human butyrylcholinesterase inhibitors for treatment of Alzheimer’s disease . Current Computer-Aided Drug Design. 10. (4). p. 335-348.

Kundaikar, Harish S., Agre, Neha P., Degani, Mariam S. (2014). Pharmacophore Based 3DQSAR of Phenothiazines as Specific Human Butyrylcholinesterase Inhibitors for Treatment of Alzheimer's Disease . Current Computer-Aided Drug Design.

Kundaikar, H.S., Agre, N.P., Degani, M.S.(2014). Pharmacophore based 3DQSAR of phenothiazines as specific human butyrylcholinesterase inhibitors for treatment of Alzheimer’s disease . Current Computer-Aided Drug Design. 10. (4). p. 335-348.

Vikas N. Telvekar, Kavit N. Patel, Harish S. Kundaikar, Hemchandra K. Chaudhari (2008). A novel system for the synthesis of nitriles from aldehydes using aqueous ammonia and sodium dichloroiodate . Tetrahedron Letters.

Telvekar, V.N., Kundaikar, H.S.(2008). GPR40 Carboxylic Acid Receptor Family and Diabetes: A New Drug Target . Current Drug Targets. 9. (10). p. 899-910.

Telvekar, V.N., Patel, K.N., Kundaikar, H.S., Chaudhari, H.K.(2008). A novel system for the synthesis of nitriles from aldehydes using aqueous ammonia and sodium dichloroiodate . Tetrahedron Letters. 49. (14). p. 2213-2215.

V. Telvekar, H. Kundaikar (2008). GPR40 carboxylic acid receptor family and diabetes: a new drug target . Current Drug Targets.

Telvekar, V.N., Kundaikar, H.S., Patel, K.N., Chaudhari, H.K.(2008). 3-D QSAR and molecular docking studies on aryl benzofuran-2-yl ketoxime derivatives as candida albicans N-myristoyl transferase inhibitors . QSAR and Combinatorial Science. 27. (10). p. 1193-1203.

Vikas N. Telvekar, Harish S. Kundaikar, Kavit N. Patel, Hemchandra K. Chaudhari (2008). 3-D QSAR and Molecular Docking Studies on Aryl Benzofuran-2-yl Ketoxime Derivatives as <i>Candida albicans</i> N-myristoyl transferase Inhibitors . QSAR & Combinatorial Science.