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Hire Dr. Grant B.

United States

USD 200 /hr

Profile Summary

Observations over a decade working as a computational biologist in academia and biotech, most of it remotely, convinced me that there was simultaneously a strong demand for quality bioinformatics services and a loss of computational biologists to other industries. Contributors to this leakage of professional talent include a shortage of desirable professional career positions, extreme geographic concentration, and an industry that has not yet widely accepted primarily remote work. Consequently, in 2018, I founded The Bioinformatics CRO as a distributed company to provide quality computational biology services drawing on top talent worldwide. I'm a computational biologist with experience in the biotech industry. My expertise is in the spatiotemporal functional patterning and evolution of brain gene expression, how and why this is disrupted in neurological disorders and neurodegenerative diseases, and how multilevel integration of a wide variety of datasets can drive more effective target identification and lead generation.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Genetics
• ☆ Bioinformatics
• ☆ Neurology

Services

• Consulting
• Data & AI
• Product Development

Work Experience

University of Oxford

- Present

Chief Executive Officer

The Bioinformatics CRO, Inc.

July 2018 - Present

Senior Genomics Scientist

Verge Genomics

2016 - June 2018

Education

Postdoctoral Fellow in Neurobehavioral Genetics (Psychiatry)

University of California Los Angeles

2012 - 2014

DPhil in Physiology, Anatomy and Genetics (Physiology, Anatomy and Genetics)

University of Oxford

- 2012

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2020). No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience . Brain sciences.

(2020). Identification of region-specific astrocyte subtypes at single cell resolution . Nature communications.

(2018). Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons . Nature medicine.

(2018). Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons . Molecular autism.

(2017). Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction . JCI insight.

Batiuk MY, de Vin F, Duqué SI, Li C, Saito T, Saido T, Fiers M, Belgard TG, Holt MG, The Journal of biological chemistry, 2017, vol. 292, no. 21, pp. 8874-8891, 2017 .

Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH, Nature, 2016, vol. 540, no. 7633, pp. 423-427, 2016 .

(2014). NSF workshop report: Discovering general principles of nervous system organization by comparing brain maps across species . Journal of Comparative Neurology. 522. (7). p. 1445-1453.

(2014). NSF workshop report: Discovering general principles of nervous system organization by comparing brain maps across species . Brain, Behavior and Evolution. 83. (1). p. 1-8.

(2014). Population structure confounds autism genetic classifier . Molecular Psychiatry. 19. (4). p. 405-407.

Belgard TG, Montiel JF, Wang WZ, García-Moreno F, Margulies EH, Ponting CP, Molnár Z, <i>Proceedings of the National Academy of Sciences of the United States of America</i>, 2013 .

Belgard TG, Jankovic I, Lowe JK, Geschwind DH, <i>Molecular psychiatry</i>, 2013 .

Hoerder-Suabedissen A, Oeschger FM, Krishnan ML, Belgard TG, Wang WZ, Lee S, Webber C, Petretto E, Edwards AD, Molnár Z, <i>Proceedings of the National Academy of Sciences of the United States of America</i>, 2013, vol. 110, no. 9, pp. 3555-3560 .

(2013). Population structure confounds autism genetic classifier . Molecular Psychiatry. Nature Publishing Group

Belgard, T.G., Montiel, J.F., Wang, W.Z., Garc&#237;a-Moreno, F., Margulies, E.H., Ponting, C.P., Moln&#225;r, Z.(2013). Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors . Proceedings of the National Academy of Sciences of the United States of America. 110. (32). p. 13150-13155.

Belgard, T.G., Geschwind, D.H.(2013). Retooling spare parts: Gene duplication and cognition . Nature Neuroscience. 16. (1). p. 6-8.

(2013). Things change: How comparative transcriptomics suggest the pallium has evolved at multiple levels of organization . Brain, Behavior and Evolution. 82. (3). p. 150-152.

Nguyen, Q, Belgard, T, Taylor, J, Murthy, V, Halas, N & Wong, M, 2012, 'Water-Phase Synthesis of Cationic Silica/Polyamine Nanoparticles', <i>Chemistry of Materials</i>, vol. 109, no. 30, pp. 14469-1433 .

Molnár, Z & Belgard, T, 2012, 'Transcriptional Profiling of Layers of the Primate Cerebral Cortex', <i>Neuron</i>, vol. 11, no. Suppl 1, pp. 139-1055 .

(2012). The genomic landscape shaped by selection on transposable elements across 18 mouse strains . Genome Biology.

Nellåker, C, Keane, T, Yalcin, B, Wong, K, Agam, A, Belgard, T, Flint, J, Adams, D, Frankel, W & Ponting, C, 2012, 'The genomic landscape shaped by selection on transposable elements across 18 mouse strains', <i>Genome Biology</i>, vol. 13, no. 6, p. R45 .

Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, Goodson M, Furlotte NA, Eskin E, Nellåker C, Whitley H, Cleak J, Janowitz D, Hernandez-Pliego P, Edwards A, Belgard TG, Oliver PL, McIntyre RE, Bhomra A, Nicod J, Gan X, Yuan W, van der Weyden L, Steward CA, Bala S, Stalker J, Mott R, Durbin R, Jackson IJ, Czechanski A, Guerra-Assunção JA, Donahue LR, Reinholdt LG, Payseur BA, Ponting CP, Birney E, Flint J, Adams DJ, <i>Nature</i>, 2011, vol. 477, no. 7364, pp. 289-294 .

Belgard, T, Marques, A, Oliver, P, Abaan, H, Sirey, T, Hoerder-Suabedissen, A, García-Moreno, F, Molnár, Z, Margulies, E & Ponting, C, 2011, 'A Transcriptomic Atlas of Mouse Neocortical Layers', <i>Neuron</i>, vol. 11, no. Database issue, pp. 139-616 .

Ponting, C.P., Grant Belgard, T.(2010). Transcribed dark matter: Meaning or myth? . Human Molecular Genetics. 19. (R2).

Ponting, C. P. and Belgard, T. G.(2010). Transcribed dark matter: meaning or myth? . Human Molecular Genetics. 19. (R2). p. R162-R168. Oxford University Press

REPORT

(2015). Elevated gene expression of most microglial markers, and reduced expression of most pyramidal neuron and interneuron markers, in postmortem autism cortex .

BOOK

(2015). The emerging picture of autism spectrum disorder: Genetics and pathology . Annual Review of Pathology: Mechanisms of Disease. 10. p. 111-144.