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Profile Details
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USD 150 /hr
Hire Dr. Ganapathy S.
United States
USD 150 /hr

Freelance Biochemist & Cancer Biologist, 15+ years experience in cancer research

Profile Summary
Subject Matter Expertise
Services
Research Fact Checking, Scientific and Technical Research
Consulting Scientific and Technical Consulting
Work Experience

Visiting Assistant Professor

Wheaton College, Norton MA

September 2024 - Present

Senior Scientist

EMD Serono

August 2021 - March 2024

Scientist

Montai Health Inc (Flagship Pioneering)

October 2020 - July 2021

Postdoctoral Fellow

Massachusetts Institute of Technology

March 2015 - September 2020

Education

PhD, Biochemistry

Rutgers University, Newark - United States

August 2008 - May 2014

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
Ganapathy Sriram, Tiffany R. Emmons, Lauren E. Milling, Darrell J. Irvine, Michael B Yaffe (2022). Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade . Molecular & Cellular Oncology.
Ganapathy Sriram, Lauren E. Milling, Jung-Kuei Chen, Yi Wen Kong, Brian A. Joughin, Wuhbet Abraham, Susanne Swartwout, Erika D. Handly, Darrell J. Irvine, Michael B. Yaffe(2021). The injury response to DNA damage in live tumor cells promotes antitumor immunity . Science Signaling. 14. (705). American Association for the Advancement of Science ({AAAS})
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Nature Communications.
(2019). Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer . Cancer research.
(2019). Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner . The journal of trauma and acute care surgery.
(2018). MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis . Proceedings of the National Academy of Sciences of the United States of America.
(2017). Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression . Molecular Cancer Research.
(2015). Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway . Nature Chemical Biology.
(2015). Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk. Oncogene.
(2014). Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity. Frontiers in Immunology.
(2014). Crk at the quarter century mark: perspectives in signaling and cancer. Journal of Cellular Biochemistry.
(2012). Commentary: The carboxyl-terminal Crk SH3 domain: Regulatory strategies and new perspectives. FEBS letters.
(2012). Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nature Chemical Biology.
(2011). Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation. Oncogene.
(2011). Expression of type II chorionic gonadotropin genes supports a role in the male reproductive system. Molecular and Cellular Biology.
(2010). Emerging roles for crk in human cancer. Genes and Cancer.
CONFERENCE POSTER
(2014). Tyrosine Phosphorylation Controls Non-canonical Domain Utilization in the Signaling Adaptor Protein Crk. FASEB – Protein Phosphorylation, Cellular Plasticity and Signal Rewiring.
(2011). Non-canonical Signaling Pathway for Crk Mediated by Tyrosine Phosphorylation of the C-terminal SH3 domain. Protein Modules and Networks in Health and Disease.
(2011). Phosphorylation of Crk at Tyrosine 251 in the RT loop of the SH3C domain downstream of EGFR: Novel Role in Abl Transactivation. Experimental Biology.
(2010). Phosphorylation of the Crk Adaptor Protein at Y251: Novel Role in Abl Kinase Trans-activation. Meeting on Protein Phosphorylation and Cell Signaling.