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Hire Dr. Furqan S.

Sweden

USD 50 /hr

Bone researcher; expertise in biomaterials selection, design, and advanced characterisation/analytical techniques

Profile Summary

I have extensive experience in the development, characterisation, in vitro and in vivo evaluation of biomaterials for bone repair/regeneration, using advanced analytical techniques incl. electron microscopy, vibrational spectroscopy, and crystallography. My education includes a Master of Science (MSc) in Dental Materials from the School of Engineering and Materials Science, Queen Mary University of London, UK (2011) and a PhD in Biomaterials from the University of Gothenburg, Sweden. During my doctoral studies, I have used electron microscopy and complementary spectroscopic techniques to correlatively investigate the complex hierarchical nature of the interface between bone and metal implants. The study material consisted of specimens obtained from experimental in vivo models, human bone biopsies, and retrieved clinical dental implants. The work focused on understanding osseointegration, and maintenance thereof, by studying the morphology of the peri-implant osteocyte lacuno-canalicular network. Through my formal education, research experience, and clinical training, I have gained extensive knowledge of biomedical materials for orthopaedic applications and hard tissue regeneration; design and characterisation of biomaterials; bone biology/morphology; and clinical/pre-clinical models for evaluating in vivo performance of bone biomaterials. As of 23 February, 2023, my publications have been cited 1873 times, giving me an h-index of 23. Google scholar: https://scholar.google.com/citations?user=RJsh1_YAAAAJ&hl=en

Subject Matter Expertise

• ★ Raman Spectroscopy
• ★ Biomaterials
• ★ Microscopy
• ☆ Medical Implants

Services

• Writing
• Research
• Data & AI

Writing Clinical Trial Documentation, Technical Writing, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis

Work Experience

Doctoral Researcher

University of Gothenburg

July 2012 - September 2017

Simulated Dental Learning Environment Tech

University of Plymouth

December 2011 - February 2012

Education

PhD (Department of Biomaterials)

University of Gothenburg

July 2012 - September 2017

MSc (School of Engineering and Materials Science)

Queen Mary, University of London

September 2010 - September 2011

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Furqan A. Shah(2020). Towards refining Raman spectroscopy-based assessment of bone composition . Scientific Reports. 10. (1). Springer Science and Business Media {LLC}

Furqan A. Shah, Krisztina Ruscsák, Anders Palmquist(2020). Transformation of bone mineral morphology: From discrete marquise-shaped motifs to a continuous interwoven mesh . Bone Reports. 13. p. 100283. Elsevier {BV}

Omar Omar, Thomas Engstrand, Lars Kihlström Burenstam Linder, Jonas Åberg, Furqan A. Shah, Anders Palmquist, Ulrik Birgersson, Ibrahim Elgali, Michael Pujari-Palmer, Håkan Engqvist, et al. (2020). In situ bone regeneration of large cranial defects using synthetic ceramic implants with a tailored composition and design . Proceedings of the National Academy of Sciences.

Furqan A. Shah(2020). Characterization of Synthetic Hydroxyapatite Fibers Using High-Resolution, Polarized Raman Spectroscopy . Applied Spectroscopy. p. 000370282094254. {SAGE} Publications

Furqan A. Shah, Shariel Sayardoust, Omar Omar, Peter Thomsen, Anders Palmquist(2019). Does Smoking Impair Bone Regeneration in the Dental Alveolar Socket? . Calcified Tissue International. 105. (6). p. 619--629. Springer Science and Business Media {LLC}

Furqan A. Shah, Krisztina Ruscsák, Anders Palmquist(2019). 50 years of scanning electron microscopy of bone{\textemdash}a comprehensive overview of the important discoveries made and insights gained into bone material properties in health, disease, and taphonomy . Bone Research. 7. (1). Springer Science and Business Media {LLC}

(2019). Exosomes influence the behavior of human mesenchymal stem cells on titanium surfaces . Biomaterials.

Furqan A. Shah, Shariel Sayardoust, Peter Thomsen, Anders Palmquist(2019). Extracellular matrix composition during bone regeneration in the human dental alveolar socket . Bone. 127. p. 244--249. Elsevier {BV}

(2019). Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone formation . The FASEB Journal.

Furqan A. Shah(2019). Micro-Raman Spectroscopy Reveals the Presence of Octacalcium Phosphate and Whitlockite in Association with Bacteria-Free Zones Within the Mineralized Dental Biofilm . Microscopy and Microanalysis. 25. (1). p. 129--134. Cambridge University Press ({CUP})

Margarita Trobos, Annika Juhlin, Furqan A. Shah, Maria Hoffman, Herman Sahlin, Christer Dahlin(2018). In vitro evaluation of barrier function against oral bacteria of dense and expanded polytetrafluoroethylene ({PTFE}) membranes for guided bone regeneration . Clinical Implant Dentistry and Related Research. Wiley

F.A. Shah, P. Thomsen, A. Palmquist(2018). A Review of the Impact of Implant Biomaterials on Osteocytes . Journal of Dental Research. p. 002203451877803. {SAGE} Publications

(2018). Interactions between monocytes, mesenchymal stem cells, and implants evaluated using flow cytometry and gene expression . Journal of Tissue Engineering and Regenerative Medicine.

(2018). Biomineralization at Titanium Revealed by Correlative 4D Tomographic and Spectroscopic Methods . Advanced Materials Interfaces.

Shah FA, Jergéus E, Chiba A, Palmquist A(2018). Osseointegration of 3D printed microalloyed CoCr implants-Addition of 0.04% Zr to CoCr does not alter bone material properties . Journal of biomedical materials research. Part A.

Shah FA, Stoica A, Cardemil C, Palmquist A(2018). Multiscale characterization of cortical bone composition, microstructure, and nanomechanical properties in experimentally induced osteoporosis . Journal of biomedical materials research. Part A.

Furqan A. Shah, Peter Thomsen, Anders Palmquist(2018). Osseointegration and current interpretations of the bone-implant interface . Acta Biomaterialia. Elsevier {BV}

Furqan A. Shah, Bryan E. J. Lee, James Tedesco, Cecilia Larsson Wexell, Cecilia Persson, Peter Thomsen, Kathryn Grandfield, Anders Palmquist(2017). Micrometer-Sized Magnesium Whitlockite Crystals in Micropetrosis of Bisphosphonate-Exposed Human Alveolar Bone . Nano Letters. 17. (10). p. 6210--6216. American Chemical Society ({ACS})

Wang, X., Shah, F.A., Palmquist, A., Grandfield, K.(2017). 3D characterization of human nano-osseointegration by on-axis electron tomography without the Missing Wedge . ACS Biomaterials Science and Engineering. 3. (1). p. 49-55.

Shah, F.A., Palmquist, A.(2017). Evidence that Osteocytes in Autogenous Bone Fragments can Repair Disrupted Canalicular Networks and Connect with Osteocytes in de novo Formed Bone on the Fragment Surface . Calcified Tissue International. p. 1-7.

Palmquist, A., Shah, F.A., Emanuelsson, L., Omar, O., Suska, F.(2017). A technique for evaluating bone ingrowth into 3D printed, porous Ti6Al4V implants accurately using X-ray micro-computed tomography and histomorphometry . Micron. 94. p. 1-8.

Furqan A. Shah, Jie Zheng, Martin L. Johansson, Omar Omar, Hanna Simonsson, Anders Palmquist, Peter Thomsen(2016). Laser-Modified Surface Enhances Osseointegration and Biomechanical Anchorage of Commercially Pure Titanium Implants for Bone-Anchored Hearing Systems . {PLOS} {ONE}. 11. (6). p. e0157504. Public Library of Science ({PLoS})

Furqan A. Shah, Omar Omar, Felicia Suska, Anders Snis, Aleksandar Matic, Lena Emanuelsson, Birgitta Norlindh, Jukka Lausmaa, Peter Thomsen, Anders Palmquist(2016). Long-term osseointegration of 3D printed {CoCr} constructs with an interconnected open-pore architecture prepared by electron beam melting . Acta Biomaterialia. 36. p. 296--309. Elsevier {BV}

Furqan A. Shah(2016). Fluoride-containing bioactive glasses: Glass design, structure, bioactivity, cellular interactions, and recent developments . Materials Science and Engineering: C. 58. p. 1279--1289. Elsevier {BV}

Furqan A. Shah, Anders Snis, Aleksandar Matic, Peter Thomsen, Anders Palmquist(2016). 3D printed Ti6Al4V implant surface promotes bone maturation and retains a higher density of less aged osteocytes at the bone-implant interface . Acta Biomaterialia. 30. p. 357--367. Elsevier {BV}

Shah, F.A., Zanghellini, E., Matic, A., Thomsen, P., Palmquist, A.(2016). The Orientation of Nanoscale Apatite Platelets in Relation to Osteoblastic–Osteocyte Lacunae on Trabecular Bone Surface . Calcified Tissue International. 98. (2). p. 193-205.

Shah, F.A., Omar, O., Suska, F., Snis, A., Matic, A., Emanuelsson, L., Norlindh, B., Lausmaa, J., Thomsen, P., Palmquist, A.(2016). Long-term osseointegration of 3D printed CoCr constructs with an interconnected open-pore architecture prepared by electron beam melting . Acta Biomaterialia. 36. p. 296-309.

Shah, F.A., Stenlund, P., Martinelli, A., Thomsen, P., Palmquist, A.(2016). Direct communication between osteocytes and acid-etched titanium implants with a sub-micron topography . Journal of Materials Science: Materials in Medicine. 27. (11).

Shah, F.A., Trobos, M., Thomsen, P., Palmquist, A.(2016). Commercially pure titanium (cp-Ti) versus titanium alloy (Ti6Al4V) materials as bone anchored implants - Is one truly better than the other? . Materials Science and Engineering C. 62. p. 960-966.

Larsson Wexell, C., Shah, F.A., Ericson, L., Matic, A., Palmquist, A., Thomsen, P.(2016). Electropolished Titanium Implants with a Mirror-Like Surface Support Osseointegration and Bone Remodelling . Advances in Materials Science and Engineering. 2016.

Shah, F.A., Johansson, M.L., Omar, O., Simonsson, H., Palmquist, A., Thomsen, P.(2016). Laser-modified surface enhances osseointegration and biomechanical anchorage of commercially pure titanium implants for bone-anchored hearing systems . PLoS ONE. 11. (6). p. 1-24.

Shah, F.A., Snis, A., Matic, A., Thomsen, P., Palmquist, A.(2016). 3D printed Ti6Al4V implant surface promotes bone maturation and retains a higher density of less aged osteocytes at the bone-implant interface . Acta Biomaterialia. 30. p. 357-367.

Shah, F.A.(2016). Fluoride-containing bioactive glasses: Glass design, structure, bioactivity, cellular interactions, and recent developments . Materials Science and Engineering C. 58. p. 1279-1289.

Shah, F.A., Brauer, D.S., Hill, R.G., Hing, K.A.(2015). Apatite formation of bioactive glasses is enhanced by low additions of fluoride but delayed in the presence of serum proteins . Materials Letters. 153. p. 143-147.

Shah, F.A., Johansson, B.R., Thomsen, P., Palmquist, A.(2015). Ultrastructural evaluation of shrinkage artefacts induced by fixatives and embedding resins on osteocyte processes and pericellular space dimensions . Journal of Biomedical Materials Research - Part A. 103. (4). p. 1565-1576.

Shah, F.A., Wang, X., Thomsen, P., Grandfield, K., Palmquist, A.(2015). High-Resolution Visualization of the Osteocyte Lacuno-Canalicular Network Juxtaposed to the Surface of Nanotextured Titanium Implants in Human . ACS Biomaterials Science and Engineering. 1. (5). p. 305-313.

Shah, F.A., Brauer, D.S., Wilson, R.M., Hill, R.G., Hing, K.A.(2014). Influence of cell culture medium composition on in vitro dissolution behavior of a fluoride-containing bioactive glass . Journal of Biomedical Materials Research - Part A. 102. (3). p. 647-654.

Shah, F.A., Nilson, B., Brånemark, R., Thomsen, P., Palmquist, A.(2014). The bone-implant interface - nanoscale analysis of clinically retrieved dental implants . Nanomedicine: Nanotechnology, Biology, and Medicine. 10. (8). p. 1729-1737.

Shah, F.A., Brauer, D.S., Desai, N., Hill, R.G., Hing, K.A.(2014). Fluoride-containing bioactive glasses and Bioglass^® 45S5 form apatite in low pH cell culture medium . Materials Letters. 119. p. 96-99.

BOOK CHAPTER

(2020). Cellular and molecular reactions to dental implants . Dental Implants and Bone Grafts.

(2019). Retrieval, sample processing, and analyses of bone-anchored implants . Bone Repair Biomaterials.

(2018). Bioactive glass and glass-ceramic scaffolds for bone tissue engineering . Bioactive Glasses.

BOOK

Shah, F.A., Grandfield, K., Palmquist, A.(2016). Laser surface modification and the tissue-implant interface . Laser Surface Modification of Biomaterials: Techniques and Applications. p. 253-280.