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Italy

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Dr. PADUANO FRANCESCO, PhD, Specialist in Medical Genetics

Profile Summary

Stem cell biology, Molecular and Cellular Oncology, Medical GENETICS, Clinical trials, Manuscript and Figure editing, Statistical Analysis

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Cell Biology
• ☆ Stem Cell Research
• ☆ Cell Aging
• ☆ Medical Genetics
• ☆ Immunogenetics
• ☆ Oncology
• ☆ Oral & Maxillofacial Surgery

Services

• Writing
• Consulting
• Data & AI
• Product Development

Work Experience

Work information not provided.

Education

Magna Graecia University, Catanzaro, Italy

Specialization in Medical GENETICS

September 2022 - January 2024

Ph.D - Molecular Oncology; Experimental and Clinical Medicine

Magna Græcia University (University in Catanzaro, Italy)

January 2008 - January 2012

Masters - Bioinformatics

University of Milano-Bicocca

January 2004 - January 2006

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2019). Strategic Tools in Regenerative and Translational Dentistry . International Journal of Molecular Sciences.

Francesco Paduano, Bruna Codispoti, Massimo Marrelli, Marco Tatullo (2018). NANOmetric BIO-Banked MSC-Derived Exosome (NANOBIOME) as a Novel Approach to Regenerative Medicine . Journal of Clinical Medicine.

(2017). TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line . British journal of haematology.

(2017). Adipose Tissue as a Strategic Source of Mesenchymal Stem Cells in Bone Regeneration: A Topical Review on the Most Promising Craniomaxillofacial Applications . International journal of molecular sciences.

(2017). Adipose Tissue as a Strategic Source of Mesenchymal Stem Cells in Bone Regeneration: A Topical Review on the Most Promising Craniomaxillofacial Applications . International Journal of Molecular Sciences.

Paduano F, Marrelli M, Alom N, Amer M, White LJ, Shakesheff KM, Tatullo M, Journal of biomaterials science. Polymer edition, 2017, vol. 28, no. 8, pp. 730-748, 2017 .

PUBMED .

(2016). Crosstalk between oral and general health status in e-smokers .

(2016). CD146 Expression Influences Periapical Cyst Mesenchymal Stem Cell Properties . Stem cell Rev.

(2016). Odontogenic Differentiation of Human Dental Pulp Stem Cells on Hydrogel Scaffolds Derived from Decellularized Bone Extracellular Matrix and Collagen Type I . PLoS One. 11. (2). p. e0148225.

Gaudio, E., Gaudio, E., Paduano, F., Ngankeu, A., Ortuso, F., Lovat, F., Pinton, S., D'Agostino, S., Zanesi, N., Aqeilan, R. I., et al.(2016). A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells . Oncotarget.

Marrelli, M., Pujia, A., Palmieri, F., Gatto, R., Falisi, G., Gargari, M., Caruso, S., Apicella, D., Rastelli, C., Nardi, G. M., et al.(2016). Innovative approach for the in vitro research on biomedical scaffolds designed and customized with CAD-CAM technology . Int J Immunopathol Pharmacol.

Tatullo M, Marrelli M, Falisi G, Rastelli C, Palmieri F, Gargari M, Zavan B, Paduano F, Benagiano V, International journal of immunopathology and pharmacology, 2015 .

(2015). Bioimpedance Detection of Oral Lichen Planus Used as Preneoplastic Model. Journal of Cancer.

Marrelli M, Paduano F, Tatullo M, Journal of dental research, 2015 .

(2015). The regenerative medicine in oral and maxillofacial surgery: The most important innovations in the clinical application of mesenchymal stem cells . International Journal of Medical Sciences. 12. (1). p. 72-77.

Marrelli, M., Marrelli, M., Falisi, G., Apicella, A., Apicella, D., Amantea, M., Cielo, A., Bonanome, L., Palmieri, F., Santacroce, L., et al.(2015). Behaviour of dental pulp stem cells on different types of innovative mesoporous and nanoporous silicon scaffolds with different functionalizations of the surfaces. J Biol Regul Homeost Agents. 29. (4). p. 991-7.

(2015). DENTAL PULP STEM CELLS AND HUMAN PERIAPICAL CYST MESENCHYMAL STEM CELLS IN BONE TISSUE REGENERATION: COMPARISON OF BASAL AND OSTEOGENIC DIFFERENTIATED GENE EXPRESSION OF A NEWLY DISCOVERED MESENCHYMAL STEM CELL LINEAGE . Journal of biological regulators and homeostatic agents. 29. (3). p. 713-718.

(2015). The Regenerative Medicine in Oral and Maxillofacial Surgery: The Most Important Innovations in the Clinical Application of Mesenchymal Stem Cells . Int J Med Sci. 12. (1). p. 72-77.

Marrelli, M., Marrelli, M., Marrelli, M., Gentile, S., Palmieri, F., Paduano, F., Tatullo, M.(2014). Correlation between Surgeon's experience, surgery complexity and the alteration of stress related physiological parameters . PLoS One. 9. (11). p. e112444.

Marrelli, M., Gentile, S., Palmieri, F., Paduano, F., Tatullo, M.(2014). Correlation between surgeon's experience, surgery complexity and the alteration of stress related physiological parameters . PLoS ONE. 9. (11).

Marrelli M, Gentile S, Palmieri F, Paduano F, Tatullo M, PloS one, 2014, vol. 9, no. 11, pp. e112444 .

Ortuso F, Paduano F, Carotenuto A, Gomez-Monterrey I, Bilotta A, Gaudio E, Sala M, Artese A, Vernieri E, Dattilo V, Iuliano R, Brancaccio D, Bertamino A, Musella S, Alcaro S, Grieco P, Perrotti N, Croce CM, Novellino E, Fusco A, Campiglia P, Trapasso F, ACS chemical biology, 2013, vol. 8, no. 7, pp. 1497-1506 .

Paduano F, Dattilo V, Narciso D, Bilotta A, Gaudio E, Menniti M, Agosti V, Palmieri C, Perrotti N, Fusco A, Trapasso F, Iuliano R, The FEBS journal, 2013, vol. 280, no. 2, pp. 401-412 .

Gaudio E, Paduano F, Ngankeu A, Lovat F, Fabbri M, Sun HL, Gasparini P, Efanov A, Peng Y, Zanesi N, Shuaib MA, Rassenti LZ, Kipps TJ, Li C, Aqeilan RI, Lesinski GB, Trapasso F, Croce CM, Blood, 2013, vol. 121, no. 2, pp. 351-359 .

(2013). Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas . Blood. 121. (2). p. 351-9.

Ortuso, F., Ortuso, F., Paduano, F., Carotenuto, A., Gomez-Monterrey, I., Bilotta, A., Gaudio, E., Sala, M., Artese, A., Vernieri, E., et al.(2013). Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation . ACS Chemical Biology. 8. (7). p. 1497-1506.

(2013). Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation . ACS Chem Biol. 8. (7). p. 1497-506.

Gaudio E, Paduano F, Spizzo R, Ngankeu A, Zanesi N, Gaspari M, Ortuso F, Lovat F, Rock J, Hill GA, Kaou M, Cuda G, Aqeilan RI, Alcaro S, Croce CM, Trapasso F, PloS one, 2013, vol. 8, no. 11, pp. e78610 .

(2013). Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel . PLoS One. 8. (11). p. e78610.

Paduano, F., Dattilo, V., Narciso, D., Bilotta, A., Gaudio, E., Menniti, M., Agosti, V., Palmieri, C., Perrotti, N., Fusco, A., et al.(2013). Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328 . FEBS J. 280. (2). p. 401-12.

(2013). Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel . PLoS ONE. 8. (11).

(2013). Cells isolated from human periapical cysts express mesenchymal stem cell-like properties . International Journal of Biological Sciences. 9. (10). p. 1070-1078.

(2013). Cells isolated from human periapical cysts express mesenchymal stem cell-like properties . Int J Biol Sci. 9. (10). p. 1070-8.

Marrelli M, Paduano F, Tatullo M, International journal of biological sciences, 2013, vol. 9, no. 10, pp. 1070-1078 .

(2013). Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328 . FEBS Journal. 280. (2). p. 401-412.

Gaudio, E., Paduano, F., Ngankeu, A., Lovat, F., Fabbri, M., Sun, H.-L., Gasparini, P., Efanov, A., Peng, Y., Zanesi, N., et al.(2013). Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas . Blood. 121. (2). p. 351-359.

Paduano F, Ortuso F, Campiglia P, Raso C, Iaccino E, Gaspari M, Gaudio E, Mangone G, Carotenuto A, Bilotta A, Narciso D, Palmieri C, Agosti V, Artese A, Gomez-Monterrey I, Sala M, Cuda G, Iuliano R, Perrotti N, Scala G, Viglietto G, Alcaro S, Croce CM, Novellino E, Fusco A, Trapasso F, ACS chemical biology, 2012, vol. 7, no. 10, pp. 1666-1676 .

Gaudio E, Spizzo R, Paduano F, Luo Z, Efanov A, Palamarchuk A, Leber AS, Kaou M, Zanesi N, Bottoni A, Costinean S, Rassenti LZ, Nakamura T, Kipps TJ, Aqeilan RI, Pekarsky Y, Trapasso F, Croce CM, Blood, 2012, vol. 119, no. 1, pp. 180-187 .

Paduano, F., Ortuso, F., Campiglia, P., Raso, C., Iaccino, E., Gaspari, M., Gaudio, E., Mangone, G., Carotenuto, A., Bilotta, A., et al.(2012). Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity . ACS Chem Biol. 7. (10). p. 1666-76.

Paduano, F., Ortuso, F., Campiglia, P., Raso, C., Iaccino, E., Gaspari, M., Gaudio, E., Mangone, G., Carotenuto, A., Bilotta, A., et al.(2012). Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity . ACS Chemical Biology. 7. (10). p. 1666-1676.

Gaudio, E., Spizzo, R., Paduano, F., Luo, Z., Efanov, A., Palamarchuk, A., Leber, A. S., Kaou, M., Zanesi, N., Bottoni, A., et al.(2012). Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies . Blood. 119. (1). p. 180-7.

Peduto A, Pagano B, Petronzi C, Massa A, Esposito V, Virgilio A, Paduano F, Trapasso F, Fiorito F, Florio S, Giancola C, Galeone A, Filosa R, Bioorganic & medicinal chemistry, 2011, vol. 19, no. 21, pp. 6419-6429 .

Peduto, A., Pagano, B., Petronzi, C., Peduto, A., Pagano, B., Petronzi, C., Massa, A., Esposito, V., Virgilio, A., Paduano, F., et al.(2011). Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands . Bioorganic and Medicinal Chemistry. 19. (21). p. 6419-6429.

(2011). Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands . Bioorg Med Chem. 19. (21). p. 6419-29.

Alcaro S, Artese A, Iley JN, Missailidis S, Ortuso F, Parrotta L, Pasceri R, Paduano F, Sissi C, Trapasso F, Vigorita MG, ChemMedChem, 2010, vol. 5, no. 4, pp. 575-583 .

(2010). Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties . ChemMedChem. 5. (4). p. 575-83.

(2010). Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties . ChemMedChem. 5. (4). p. 575-583.

Caruso F, Pettinari C, Paduano F, Villa R, Marchetti F, Monti E, Rossi M, Journal of medicinal chemistry, 2008, vol. 51, no. 6, pp. 1584-1591 .

Caruso, F., Caruso, F., Pettinari, C., Paduano, F., Villa, R., Marchetti, F., Monti, E., Rossi, M.(2008). Chemical behavior and in vitro activity of mixed phosphine gold(I) compounds on melanoma cell lines . J Med Chem. 51. (6). p. 1584-91.

Caruso, F., Pettinari, C., Paduano, F., Villa, R., Marchetti, F., Monti, E., Rossi, M.(2008). Chemical behavior and in vitro activity of mixed phosphine gold(I) compounds on melanoma cell lines . Journal of Medicinal Chemistry. 51. (6). p. 1584-1591.

Paduano F, Villa R, Pennati M, Folini M, Binda M, Daidone MG, Zaffaroni N, Molecular cancer therapeutics, 2006, vol. 5, no. 1, pp. 179-186 .

(2006). Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells . Mol Cancer Ther. 5. (1). p. 179-86.

Paduano, F., Paduano, F., Villa, R., Pennati, M., Folini, M., Binda, M., Grazia, M., Zaffaroni, N.(2006). Silencing of suvivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells . Molecular Cancer Therapeutics. 5. (1). p. 179-186.

Folini M, Brambilla C, Villa R, Gandellini P, Vignati S, Paduano F, Daidone MG, Zaffaroni N, European journal of cancer (Oxford, England : 1990), 2005, vol. 41, no. 4, pp. 624-634 .

Folini, M., Brambilla, C., Villa, R., Gandellini, P., Vignati, S., Paduano, F., Daidone, M.G., Zaffaroni, N.(2005). Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells . European Journal of Cancer. 41. (4). p. 624-634.

(2005). Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells . Eur J Cancer. 41. (4). p. 624-34.

BOOK CHAPTER

(2016). DSC-differentiated hepatocytes for treatment of liver diseases . Dental Stem cells: Regenerative Potential.

(2016). Dental stem cells . Stem cells in clinical applications. Bone and cartilage Regeneration.