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Hire Dr. Evan S.

Hungary

USD 150 /hr

Molecular/Cellular Biologist & Bioinformaticist (Ph.D.)

Profile Summary

- 15+ years of experience in experimental and computational research in the field of molecular and cellular biology with a focus on cell signaling, human genetics and gene regulation - Ph.D. in Medicine (worked to identify novel drug targets in the cancer neuroblastoma using a combined experimental and computational approach) - B.S. in Bioinformatics - Postdoctoral experience in the fields of basic metabolism, longevity, cancer and neurodegenerative disease - Industry experience in the field of cancer drug target validation and biomarker identification - 15 original publications in international peer-reviewed scientific journals - Working experience in both Europe and the United States

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Genomics
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Gene Expression Analysis
• ☆ Recombinant DNA
• ☆ DNA/Gene Synthesis
• ☆ Oligonucleotide Synthesis
• ☆ Plasmid DNA
• ☆ ChIP-Seq
• ☆ Kinases
• ☆ Cell Biology
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Cell Culture
• ☆ Cell Line Engineering
• ☆ Blotting
• ☆ Cell Aging

Services

• Writing
• Research
• Consulting

Writing Technical Writing, Creative Writing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Work Experience

Scientific Advisor

Teuton Tech LLC

September 2018 - Present

Head of Biology

Turbine

May 2022 - January 2023

Postdoctoral Fellow

University of Zurich

April 2020 - March 2022

Postdoctoral Fellow

Weill Cornell Medicine

January 2016 - June 2018

Researcher (Ph.D. student)

University of Amsterdam

April 2007 - October 2015

Research Collaborator

Stanford University

April 2005 - February 2007

Research Intern

Philips

April 2006 - September 2006

Research Intern

Wyeth Research

June 2004 - August 2004

Research Intern

Wyeth Research

June 2003 - August 2003

Education

Ph.D. Medicine

University of Amsterdam

April 2007 - October 2015

Ph.D. Biology

Cold Spring Harbor Laboratory (CSHL)

September 2004 - October 2005

B.S. Bioinformatics

Rochester Institute of Technology (RIT)

September 2000 - May 2004

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Evan Santo, Rasmus Ribel‐Madsen, Peter J. Stroeken, Vincent C. J. de Boer, Ninna S. Hansen, Maaike Commandeur, Allan A. Vaag, Rogier Versteeg, Ji-hye Paik, Ellen M. Westerhout(2023). FOXO3A‐short is a novel regulator of non‐oxidative glucose metabolism associated with human longevity . Aging Cell. Wiley

Evan E. Santo, Ji-hye Paik(2018). A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene . Gene. 673. p. 95--101. Elsevier {BV}

Inah Hwang, Hwanhee Oh, Evan Santo, Do-Yeon Kim, John W. Chen, Roderick T. Bronson, Jason W. Locasale, Yoonmi Na, Jaclyn Lee, Stewart Reed, et al.(2018). FOXO protects against age-progressive axonal degeneration . Aging Cell. 17. (1). p. e12701. Wiley

Tijana Borovski, Thomas T Vellinga, Jamila Laoukili, Evan E Santo, Szabolcs Fatrai, Susanne van Schelven, Andre Verheem, Dieuwke L Marvin, Inge Ubink, Inne H M Borel Rinkes, et al.(2017). Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer . Gut. 66. (6). p. 1106--1115. {BMJ}

Laurel T. Bate-Eya, Ilona J.M. den Hartog, Ida van der Ploeg, Linda Schild, Jan Koster, Evan E. Santo, Ellen M. Westerhout, Rogier Versteeg, Huib N. Caron, Jan J. Molenaar, et al.(2016). High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition . Oncotarget. 7. (19). p. 27946--27958. Impact Journals, {LLC}

Evan E. Santo, Jihye Paik(2016). FOXO3a & haematopoietic stem cells: Goodbye PI3K, hello SIRT1? . Cell Cycle. 15. (7). p. 879--880. Informa {UK} Limited

Evan E. Santo, Peter Stroeken, Peter V. Sluis, Jan Koster, Rogier Versteeg, Ellen M. Westerhout(2013). FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma . Cancer Research. 73. (7). p. 2189--2198. American Association for Cancer Research ({AACR})

Dervis A.M. Salih, Asim J. Rashid, Damien Colas, Luis de la Torre-Ubieta, Ruo P. Zhu, Alexander A. Morgan, Evan E. Santo, Duygu Ucar, Keerthana Devarajan, Christina J. Cole, et al.(2012). FoxO6 regulates memory consolidation and synaptic function . Genes & Development. 26. (24). p. 2780--2801. Cold Spring Harbor Laboratory

E E Santo, M E Ebus, J Koster, J H Schulte, A Lakeman, P van Sluis, J Vermeulen, D Gisselsson, I Øra, S Lindner, et al.(2012). Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma . Oncogene. 31. (12). p. 1571--1581. Springer Science and Business Media {LLC}

Jan J. Molenaar, Jan Koster, Danny A. Zwijnenburg, Peter van Sluis, Linda J. Valentijn, Ida van der Ploeg, Mohamed Hamdi, Johan van Nes, Bart A. Westerman, Jennemiek van Arkel, et al.(2012). Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes . Nature. 483. (7391). p. 589--593. Springer Science and Business Media {LLC}

V M Renault, P U Thekkat, K L Hoang, J L White, C A Brady, D Kenzelmann Broz, O S Venturelli, T M Johnson, P R Oskoui, Z Xuan, et al.(2011). The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor . Oncogene. 30. (29). p. 3207--3221. Springer Science and Business Media {LLC}

J J Molenaar, M E Ebus, J Koster, E Santo, D Geerts, R Versteeg, H N Caron(2010). Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells . Oncogene. 29. (18). p. 2739--2745. Springer Science and Business Media {LLC}

Pantelis Hatzis, Laurens G. van der Flier, Marc A. van Driel, Victor Guryev, Fiona Nielsen, Sergei Denissov, Isaäc J. Nijman, Jan Koster, Evan E. Santo, Willem Welboren, et al.(2008). Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells . Molecular and Cellular Biology. 28. (8). p. 2732--2744. Informa {UK} Limited

BOOK CHAPTER

Evan E. Santo, Jihye Paik(2018). FOXO in Neural Cells and Diseases of the Nervous System . Current Topics in Developmental Biology. p. 105--118. Elsevier

CONFERENCE PAPER

Evan Santo, Nevenka Dimitrova(2007). Improvement of Spectral Analysis as a Genomic Analysis Tool . 2007 IEEE International Workshop on Genomic Signal Processing and Statistics. {IEEE}