Why Kolabtree
Getting started is quick and easy. No upfront fees
It’s free to request a service and invite bids from experts
Discuss requirements with the expert in detail before accepting statement of work from Kolabtree
Collaborate with the expert directly to get your work done the right way
Fund project when you hire the expert, but approve the deliverables only once work is done
Want to hire this expert for a project? Request a quote for free.
Profile Details
Create Project
★★★★★
☆☆☆☆☆
Hire Dr. Emmanuel X.
Profile Summary
Subject Matter Expertise
Services
Work Experience

Senior Medical Advisor

Takeda Pharmaceuticals UK Ltd

November 2019 - Present

UK Medical Lead Immunology HAE

Shire Pharmaceuticals Limited

October 2016 - October 2019

UK Medical Lead Immunology

Baxalta AG

June 2016 - September 2016

Research Fellow in Immunology of Liver Transplantation

King's College London

September 2011 - September 2014

Research Fellow in Immunology of Liver Transplantation

Institute of Liver Studies, King’s College London

August 2011 - August 2014

Senior Investigator in Asthma Immunotherapy

King's College London

October 2008 - August 2011

Senior Investigator in Asthma Immunotherapy

MRC and Asthma-UK Centre for Allergic Mechanisms in Asthma, King's College London

September 2008 - July 2011

Post-doctoral Research Fellow

King's College London

May 2004 - September 2008

Senior Investigator in Asthma Immunotherapy

Department of Asthma, Allergy and Respiratory sciences, King’s College London

April 2004 - August 2008

PhD student

INSERM U563

September 2000 - March 2004

PhD student

Physiopathology Centre of Toulouse-Purpan (CPTP, INSERM), Toulouse France

August 2000 - March 2004

Specialist registrar in Clinical Bio-Pathology

Clinical Immunology and Cell Therapy, University Hospital of Toulouse,

August 1998 - August 2000

Education

PhD (School of Biological Sciences, Health and Biotechnology)

Université Paul Sabatier - Complexe Scientifique de Rangueil

September 2000 - March 2004

PhD

School of Biological sciences, Health and Biotechnology, University Paul Sabatier, Toulouse, France

August 2000 - March 2004

MD (School of medicine)

Université Paul Sabatier

September 1993 - August 2000

MD

University Paul Sabatier, School of medicine, Toulouse France

August 1995 - March 2000

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
J. E. Vasiliou, S. Lui, S. A. Walker, V. Chohan, E. Xystrakis, A. Bush, C. M. Hawrylowicz, S. Saglani, C. M. Lloyd(2014). Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease . Allergy. 69. (10). p. 1380--1389. Wiley-Blackwell
J.Z.H. Neo, X. Huang, E. Xystrakis, M.S. Longhi, W. Jassem, G. Mieli-Vergani, D. Vergani, Y. Ma(2014). P388 {NK} {AND} {NKT} {CELLS} {EXPRESSING} {CD}161 {\textendash} A C-{TYPE} {LECTIN} {CONFERRING} {REGULATORY} {PROPERTIES} {\textendash} {ARE} {MARKEDLY} {REDUCED} {IN} {AUTOIMMUNE} {HEPATITIS} . Journal of Hepatology. 60. (1). p. S197. Elsevier {BV}
A. Sen, M. Shkodra, M. Tena, E. Xystrakis, P. Srinivasan, H. Vilca-Melendez, N. Heaton, Y. Ma, W. Jassem, C. Legido-Quigley(2014). P6 {LIPIDOME} {INVESTIGATION} {OF} {DBD}, {DCD} {AND} {LRD} {LIVERS} {SHOWS} {DIFFERENCES} {IN} {LIPID} {MEDIATED} {INTRACELLULAR} {SIGNALLING} {PATHWAYS} . Journal of Hepatology. 60. (1). p. S68. Elsevier {BV}
R. Sharma, Y. Jabri, E. Xystrakis, P. Srinivasan, A. Prachalias, X. Huang, G.M. Vijay, N. Heaton, Y. Ma, W. Jassem(2014). P13 {HUMAN} {INTRAHEPATIC} {CD}4CD25FOXP3 {REGULATORY} T {CELLS} {TREATED} {BY} {RAPAMYCIN} {AND} {RETINOIC} {ACID} {EFFECTIVELY} {SUPPRESS} {ALLOGENIC} T {EFFECTORS} {OF} {PERIPHERAL} {BLOOD} . Journal of Hepatology. 60. (1). p. S70--S71. Elsevier {BV}
E. Xystrakis, X. Huang, S. Fuggle, N. Heaton, Y. Ma, W. Jassem(2013). 188 {THE} {MODE} {OF} {DEATH} {OF} {THE} {LIVER} {DONOR} {IMPRINTS} {DISTINCT} {IMMUNE} {ADAPTIVE} {RESPONSES} {ON} {THE} {HEPATIC} {RESIDENT} {LYMPHOCYTES} . Journal of Hepatology. 58. p. S83. Elsevier {BV}
A. Gupta, S. Dimeloe, D. F. Richards, E. S. Chambers, C. Black, Z. Urry, K. Ryanna, E. Xystrakis, A. Bush, S. Saglani, et al.(2013). Defective {IL}-10 expression and in vitro steroid-induced {IL}-17A in paediatric severe therapy-resistant asthma . Thorax. 69. (6). p. 508--515. {BMJ}
Emmanuel Xystrakis, Zoë Urry, Emma S. Chambers, Sarah Dimeloe, David F. Richards, Leona Gabryšová, Jillian Christensen, Atul Gupta, Sejal Saglani, Andrew Bush, et al.(2012). The role of 1$\upalpha$,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3 $\mathplus$ and {IL}-10 $\mathplus$ {CD}4 $\mathplus$ T cells . European Journal of Immunology. 42. (10). p. 2697--2708. Wiley-Blackwell
Emmanuel Xystrakis, Robin Daniel Abeles, Mark J. McPhail, David Sowter, Charalambos G. Antoniades, Nikhil Vergis, Godhev K. Manakkat Vijay, Wafa Khamri, Debbie L. Shawcross, Yun Ma, et al.(2012). {CD}14, {CD}16 and {HLA}-{DR} reliably identifies human monocytes and their subsets in the context of pathologically reduced {HLA}-{DR} expression by {CD}14hi/{CD}16neg monocytes: Expansion of {CD}14hi/{CD}16pos and contraction of {CD}14lo/{CD}16pos monocytes in acute liver fail . Cytometry Part A. 81A. (10). p. 823--834. Wiley-Blackwell
Emmanuel Xystrakis, Zoë Urry, David F. Richards, Joanne McDonald, Zahid Sattar, David J. Cousins, Christopher J. Corrigan, Emma Hickman, Zarin Brown, Catherine M. Hawrylowicz(2009). Ligation of {TLR}9 induced on human {IL}-10{\textendash}secreting Tregs by 1$\upalpha$,25-dihydroxyvitamin D3 abrogates regulatory function . Journal of Clinical Investigation. American Society for Clinical Investigation
Emmanuel Xystrakis, Zoë Urry, Catherine M Hawrylowicz(2007). Regulatory T cell therapy as individualized medicine for asthma and allergy . Current Opinion in Allergy and Clinical Immunology. 7. (6). p. 535--541. Ovid Technologies (Wolters Kluwer Health)
Emmanuel Xystrakis, Catherine Hawrylowicz, Zoe Urry, Patricia Ozegbe, Chris Corrigan, Dave Richards(2007). Drug-induced T regulatory cells in asthma . World Allergy Organization Journal. {\&}{NA}$\mathsemicolon$. p. S37--S38. Ovid Technologies (Wolters Kluwer Health)
Emmanuel Xystrakis, Zoë Urry, Catherine M. Hawrylowicz(2006). Interleukin-10-Secreting regulatory T cells in allergy and asthma . Curr Allergy Asthma Rep. 6. (5). p. 363--371. Springer Science $\mathplus$ Business Media
Emmanuel Xystrakis, Zoë Urry, Nabila Mahfiche, Patricia Ozegbe, Sandra Boswell, Catherine M Hawrylowicz(2006). Vitamin D3 in inflammatory airway disease and immunosuppression . Drug Discovery Today: Disease Mechanisms. 3. (1). p. 91--97. Elsevier {BV}
E Xystrakis, S E Boswell, C M Hawrylowicz(2006). T regulatory cells and the control of allergic disease . Expert Opin. Biol. Ther. 6. (2). p. 121--133. Informa Healthcare
E. Xystrakis(2004). Identification of a novel natural regulatory {CD}8 T-cell subset and analysis of its mechanism of regulation . Blood. 104. (10). p. 3294--3301. American Society of Hematology
E. Xystrakis, P. Cavailles, A. S. Dejean, B. Cautain, C. Colacios, D. Lagrange, M.-J. van de Gaar, I. Bernard, D. Gonzalez-Dunia, J. Damoiseaux, et al.(2004). Functional and Genetic Analysis of Two {CD}8 T Cell Subsets Defined by the Level of {CD}45RC Expression in the Rat . The Journal of Immunology. 173. (5). p. 3140--3147. The American Association of Immunologists
Emmanuel Xystrakis, Isabelle Bernard, Anne S. Dejean, Talal Alsaati, Philippe Druet, Abdelhadi Saoudi(2004). Alloreactive {CD}4 T lymphocytes responsible for acute and chronic graft-versus-host disease are contained within the {CD}45RChigh but not the {CD}45RClow subset . European Journal of Immunology. 34. (2). p. 408--417. Wiley-Blackwell
B. Cautain, J. Damoiseaux, I. Bernard, E. Xystrakis, E. Fournie, P. van Breda Vriesman, P. Druet, A. Saoudi(2002). The {CD}8 T Cell Compartment Plays a Dominant Role in the Deficiency of Brown-Norway Rats to Mount a Proper Type 1 Immune Response . The Journal of Immunology. 168. (1). p. 162--170. The American Association of Immunologists
Emmanuel Xystrakis, Lucette Pelletier, Magali Savignac, Valérie Duplan, Philippe Druet, Saoudi Abdelhadi(2001). Self major histocompatibility complex class-{II}-specific regulatory {CD}4~T cells prevent both Th1- and Th2-mediated autoimmune diseases in the rat . Microbes and Infection. 3. (11). p. 955--960. Elsevier {BV}
J.-F. Subra, B. Cautain, E. Xystrakis, M. Mas, D. Lagrange, H. van der Heijden, M.-J. van de Gaar, P. Druet, G. J. Fournie, A. Saoudi, et al.(2001). The Balance Between {CD}45RChigh and {CD}45RClow {CD}4 T Cells in Rats Is Intrinsic to Bone Marrow-Derived Cells and Is Genetically Controlled . The Journal of Immunology. 166. (5). p. 2944--2952. The American Association of Immunologists
Emmanuel Xystrakis, Gilbert J. Fournie, Bastien Cautain, Jan Damoiseaux, Magali Mas Dominique Lagrange, Isabelle Bernard, Jean-Francois Subra, Lucette Pelletier, Philippe Druet, Abdelhadi Saoudi(2001). Cellular and genetic factors involved in the difference between Brown Norway and Lewis rats to develop respectively type-2 and type-1 immune-mediated diseases . Immunol Rev. 184. (1). p. 145--160. Wiley-Blackwell