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Italy

USD 30 /hr

Postdoctoral Research Fellow. Expert in Nanocarriers and Drug Delivery Systems for Ocular and Neurodegenerative Diseases

Profile Summary

Postdoctoral Research Fellow with a PhD in Neuroscience and a strong multidisciplinary background in pharmaceutical nanotechnology, nanomedicine, and drug delivery systems. Experienced in the design, development, and optimization of nanosized carriers for targeted drug delivery to the eye and brain, with a focus on ocular degenerative diseases and neuronal disorders. During the PhD and subsequent postdoctoral research at the University of Catania, conducted advanced studies on Self-Nanoemulsifying Drug Delivery Systems (SNEDDS), nanostructured lipid carriers, polymeric micelles, and nanocrystals, applying Design of Experiments (DoE) methodologies for formulation optimization and characterization, stability and quality studies following ICH and ISO standards. Visiting experience at Queen’s University Belfast (UK) provided expertise in microfluidics, 3D printing, rheology, and scaffold design for intravitreal implantation. Actively involved in scientific project writing. Author and co-author of over 14 peer-reviewed publications in high-impact journals and several conference communications, with awards including the Alessandro Rigamonti Award (AFI 2024), SCI Fellowship (AMYC-BIOMED 2025), and Top Poster Award (CRS 2024). Member of multiple professional societies (CRS, SCI, SITELF) and Early Career Editorial Board Member for Pharmaceutics. Highly skilled in formulation design, physicochemical characterization, analytical evaluation, and preclinical studies, as well as in data analysis using DoE software, GraphPad Prism, and Minitab. Demonstrates strong communication abilities through numerous national and international presentations and scientific dissemination activities. Dedicated to innovation in translational drug delivery, with ongoing research aimed at developing advanced nanoplatforms for the prevention and treatment of ocular and neurodegenerative diseases.

Subject Matter Expertise

• ☆ Materials Science & Engineering
• ☆ Nanotechnology & Nanomaterials
• ☆ Pharmacy
• ☆ Drug Development
• ☆ Drug Formulation
• ☆ Solid Form Screening
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Bioavailability
• ☆ Pharmaceutical Manufacturing
• ☆ Pharmaceutical Process Development
• ☆ Optometry
• ☆ Vision Therapy
• ☆ Ophthalmology
• ☆ Neuro-Ophthalmology
• ☆ Stability Testing

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Medical Writing, Technical Writing, General Proofreading & Editing

Research Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting, Regulatory Consulting, Manufacturing Consulting

Data & AI Predictive Modeling, Statistical Analysis

Product Development Formulation, Recipe Development, Deformulation, Stability/Shelf Life Testing, Product Evaluation, Material Sourcing, Product Validation, Manufacturing, Quality Assurance & Control (QA/QC), Product Compliance , Concept Development

Work Experience

Postdoctoral fellow

University of Catania

March 2025 - Present

PhD. Researcher

University of Catania

October 2021 - November 2024

Predoctoral Researcher

Dr Reddy's Laboratories Ltd and University of Catania

February 2021 - October 2021

Education

PhD in Neuroscience

University of Catania

November 2021 - November 2025

Master Degree in Pharmacy (Department of Drug and Health Sciences)

University of Catania

September 2014 - February 2020

Certifications

• Early Career Editorial Board Member of Pharmaceutics

  Pharmaceutics (MDPI)

  August 2025 - Present

• PhD in neuroscience

  Univesrity of Catania

  April 2025 - Present

• Life Science Technology Treasfer Office Network training course

  University of Catania and University of Messina

  January 2024 - Present

• Special issues in Patent Law. Course: European Intellectual Property Law

  University of Catania

  May 2022 - Present

• IELTS English

  British Council

  January 2021 - January 2023

Publications

JOURNAL ARTICLE

Elide Zingale, Angela Bonaccorso, Claudia Carbone, Teresa Musumeci, Rosario Pignatello (2025). A current overview of polyions and polyelectrolyte complexes for pharmaceutical applications with special emphasis to brain purposes . Journal of Pharmaceutical Investigation.

Elide Zingale, Federica Conti, Francesca Lazzara, Kyriaki Thermos, Dimitris Spyridakos, Giovanni Luca Romano, Serena Di Martino, Vincenzo Micale, Martin Kuchar, Angelo Spadaro, et al. (2025). Retinal pharmacodynamic and pharmacokinetic profile of cannabidiol in an in vivo model of retinal excitotoxicity . European Journal of Pharmacology.

Elide Zingale, Sebastiano Masuzzo, Tatu Lajunen, Mika Reinisalo, Jarkko Rautio, Valeria Consoli, Agata Grazia D’Amico, Luca Vanella, Rosario Pignatello (2025). Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS) . Pharmaceuticals.

Elide Zingale, Sebastiano Masuzzo, Tatu Lajunen, Mika Reinisalo, Jarkko Rautio, Valeria Consoli, Agata Grazia D’Amico, Luca Vanella, Rosario Pignatello (2025). Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS) . Pharmaceuticals.

Elide Zingale, Edward Weaver, Pietro Maria Bertelli, Imre Lengyel, Rosario Pignatello, Dimitrios A. Lamprou (2024). Development of dual drug loaded-hydrogel scaffold combining microfluidics and coaxial 3D-printing for intravitreal implantation . International Journal of Pharmaceutics.

Elide Zingale, Angela Bonaccorso, Angelo Spadaro, Claudia Carbone, Teresa Musumeci, Pradip K. Sasmal, Dhanoj Reddy Doni, Rajasekhar Jaladi, Basant Amarji, Ganesh Ramachandran, et al. (2024). Lipid-based nanocarriers mediated Axitinib retinal delivery after topical instillation: Formulations setting up and in vivo evidence . Journal of Drug Delivery Science and Technology.

Elide Zingale, Angela Bonaccorso, Agata Grazia D’Amico, Rosamaria Lombardo, Velia D’Agata, Jarkko Rautio, Rosario Pignatello (2024). Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments . Pharmaceutics.

Elide Zingale, Angela Bonaccorso, Agata Grazia D’Amico, Rosamaria Lombardo, Velia D’Agata, Jarkko Rautio, Rosario Pignatello (2024). Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments . Pharmaceutics.

S. Rizzo, E. Zingale, R. Lombardo, R. Pignatello (2023). Food-grade polymers: A new vision in the controlled release of bioactive substances . Journal of Physics: Conference Series.

Elide Zingale, Salvatore Rizzo, Alessia Romeo, Rosamaria Lombardo, Rosario Pignatello(2023). Colon Delivery of Nutraceutical Ingredients by Food-Grade Polymeric Systems: An Overview of Technological Characterization and Biological Evaluation . Applied Sciences. 13. (9). p. 5443. {MDPI} {AG}

Elide Zingale, Rosario Pignatello, Salvatore Rizzo, Giuseppe Cosentino, Angela Bonaccorso, Salvatore Petralia, Francesca Monforte, Guglielmo G. Condorelli, Claudia Carbone(2023). Microscopic Evidence of the Behavior of PH-sensitive Food-grade Polymeric Delivery Systems . Current Nutraceuticals. 04. Bentham Science Publishers Ltd.

Optimization of Lipid Nanoparticles by Response Surface Methodology to Improve the Ocular Delivery of Diosmin: Characterization and In-Vitro Anti-Inflammatory Assessment <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Pharmaceutics.

Elide Zingale, Salvatore Rizzo, Angela Bonaccorso, Valeria Consoli, Luca Vanella, Teresa Musumeci, Angelo Spadaro, Rosario Pignatello (2022). Optimization of Lipid Nanoparticles by Response Surface Methodology to Improve the Ocular Delivery of Diosmin: Characterization and <i>In-Vitro</i> Anti-Inflammatory Assessment . Pharmaceutics.

Elide Zingale, Rosario Pignatello, Roberta Corsaro, Angela Bonaccorso, Claudia Carbone, Teresa Musumeci(2022). Soluplus® polymeric nanomicelles improve solubility of BCS-class II drugs . Drug Delivery and Translational Research. 12. (8). p. 1991--2006. Springer Science and Business Media {LLC}

Elide Zingale, Patrizia Nadia Hanieh, Angela Bonaccorso, Silvia Cimarelli, Eliana B. Souto, Federica Rinaldi, Carlotta Marianecci, Rosario Pignatello, Maria Carafa(2022). Almond oil O/W nanoemulsions: Potential application for ocular delivery . Journal of Drug Delivery Science and Technology. 72. p. 103424. Elsevier {BV}

Elide Zingale, Alessia Romeo, Salvatore Rizzo, Cinzia Cimino, Angela Bonaccorso, Claudia Carbone, Teresa Musumeci, Rosario Pignatello(2022). Fluorescent Nanosystems for Drug Tracking and Theranostics: Recent Applications in the Ocular Field . Pharmaceutics. 14. (5). p. 955. {MDPI} {AG}

Elide Zingale, Alessia Romeo, Salvatore Rizzo, Cinzia Cimino, Angela Bonaccorso, Claudia Carbone, Teresa Musumeci, Rosario Pignatello (2022). Fluorescent Nanosystems for Drug Tracking and Theranostics: Recent Applications in the Ocular Field . Pharmaceutics.

Elide Zingale, Angela Bonaccorso, Claudia Carbone, Teresa Musumeci, Rosario Pignatello(2022). Drug Nanocrystals: Focus on Brain Delivery from Therapeutic to Diagnostic Applications . Pharmaceutics. 14. (4). p. 691. {MDPI} {AG}

Elide Zingale, Angela Bonaccorso, Claudia Carbone, Teresa Musumeci, Rosario Pignatello (2022). Drug Nanocrystals: Focus on Brain Delivery from Therapeutic to Diagnostic Applications . Pharmaceutics.

Zingale, E., Bonaccorso, A., Carbone, C., Musumeci, T., Pignatello, R.(2022). Drug Nanocrystals: Focus on Brain Delivery from Therapeutic to Diagnostic Applications . Pharmaceutics. 14. (4).

Zingale, E., Romeo, A., Rizzo, S., Cimino, C., Bonaccorso, A., Carbone, C., Musumeci, T., Pignatello, R.(2022). Fluorescent Nanosystems for Drug Tracking and Theranostics: Recent Applications in the Ocular Field . Pharmaceutics. 14. (5).

PREPRINT

Elide Zingale, Sebastiano Masuzzo, Tatu Lajunen, Mika Reinisalo, Jarkko Rautio, Valeria Consoli, Agata G. D&#39;Amico, Luca Vanella, Rosario Pignatello (2025). Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS) .

WORKING PAPER

Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS) .