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Profile Details
Subject Matter Expertise
Services
Work Experience
Postdoctoral scholar
University of California, San Francisco
April 2016 - Present
University of California San Francisco
April 2016 - Present 
Graduate research assistant
University of Miami
August 2011 - April 2016
Education
PhD
University of Miami
August 2011 - April 2016
MS
Moscow State University
September 2009 - May 2011
BSc
Moscow State University
September 2005 - May 2009
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Sorrells, S.F., Paredes, M.F., Velmeshev, D., Herranz-Pérez, V., Sandoval, K., Mayer, S., Chang, E.F., Insausti, R., Kriegstein, A.R., Rubenstein, J.L., et al.(2019). Immature excitatory neurons develop during adolescence in the human amygdala . Nature Communications. 10. (1).
(2019). Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex . Neuron. 102. (1). p. 143-158.e7.
(2019). Neuronal vulnerability and multilineage diversity in multiple sclerosis . Nature.
Velmeshev, D., Schirmer, L., Jung, D., Haeussler, M., Perez, Y., Mayer, S., Bhaduri, A., Goyal, N., Rowitch, D.H., Kriegstein, A.R.(2019). Single-cell genomics identifies cell type–specific molecular changes in autism . Science. 364. (6441). p. 685-689.
Sartor, G.C., Powell, S.K., Velmeshev, D., Lin, D.Y., Magistri, M., Wiedner, H.J., Malvezzi, A.M., Andrade, N.S., Faghihi, M.A., Wahlestedt, C.(2017). Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens . Molecular and Cellular Neuroscience. 85. p. 183-189.
Pardo, M., Cheng, Y., Velmeshev, D., Magistri, M., Eldar-Finkelman, H., Martinez, A., Faghihi, M.A., Jope, R.S., Beurel, E.(2017). Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice . JCI insight. 2. (6). p. e91782.
Grieco, S.F., Velmeshev, D., Magistri, M., Eldar-Finkelman, H., Faghihi, M.A., Jope, R.S., Beurel, E.(2017). Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3 . World Journal of Biological Psychiatry. 18. (6). p. 445-456.
(2017). Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex . Science. 358. (6368). p. 1318-1323.
Chang, K.-C., Hertz, J., Zhang, X., Jin, X.-L., Shaw, P., Derosa, B.A., Li, J.Y., Venugopalan, P., Valenzuela, D.A., Patel, R.D., et al.(2017). Novel regulatory mechanisms for the SoxC transcriptional network required for visual pathway development . Journal of Neuroscience. 37. (19). p. 4967-4981.
Magistri, M., Khoury, N., Mazza, E.M.C., Velmeshev, D., Lee, J.K., Bicciato, S., Tsoulfas, P., Faghihi, M.A.(2016). A comparative transcriptomic analysis of astrocytes differentiation from human neural progenitor cells . European Journal of Neuroscience. 44. (10). p. 2858-2870.
Magistri, M., Velmeshev, D., Makhmutova, M., Patel, P., Sartor, G.C., Volmar, C.-H., Wahlestedt, C., Faghihi, M.A.(2016). The BET-bromodomain inhibitor JQ1 reduces inflammation and tau phosphorylation at ser396 in the brain of the 3xTg model of Alzheimer’s disease . Current Alzheimer Research. 13. (9). p. 985-995.
Peschansky, V.J., Pastori, C., Zeier, Z., Wentzel, K., Velmeshev, D., Magistri, M., Silva, J.P., Wahlestedt, C.(2016). The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans . Molecular and Cellular Neuroscience. 74. p. 49-57.
Velmeshev, D., Lally, P., Magistri, M., Faghihi, M.A.(2016). CANEapp: A user-friendly application for automated next generation transcriptomic data analysis . BMC Genomics. 17. (1).
Peschansky, V.J., Pastori, C., Zeier, Z., Motti, D., Wentzel, K., Velmeshev, D., Magistri, M., Bixby, J.L., Lemmon, V.P., Silva, J.P., et al.(2015). Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells . Frontiers in Genetics. 6. (Aug).
Trakhtenberg, E.F., Morkin, M.I., Patel, K.H., Fernandez, S.G., Sang, A., Shaw, P., Liu, X., Wang, Y., Mlacker, G.M., Gao, H., et al.(2015). The N-terminal set-β protein isoform induces neuronal death . Journal of Biological Chemistry. 290. (21). p. 13417-13426.
Bobkova, N.V., Evgen'ev, M., Garbuz, D.G., Kulikov, A.M., Morozov, A., Samokhin, A., Velmeshev, D., Medvinskaya, N., Nesterova, I., Pollock, A., et al.(2015). Exogenous Hsp70 delays senescence and improves cognitive function in aging mice . Proceedings of the National Academy of Sciences of the United States of America. 112. (52). p. 16006-16011.
Magistri, M., Velmeshev, D., Makhmutova, M., Faghihi, M.A.(2015). Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs . Journal of Alzheimer's Disease. 48. (3). p. 647-665.
Fatemi, R.P., Velmeshev, D., Faghihi, M.A.(2014). De-repressing LncRNA-targeted genes to upregulate gene expression: Focus on small molecule therapeutics . Molecular Therapy - Nucleic Acids. 3. p. e196.
Pronin, A., Levay, K., Velmeshev, D., Faghihi, M., Shestopalov, V.I., Slepak, V.Z.(2014). Expression of olfactory signaling genes in the eye . PLoS ONE. 9. (4).
(2013). Calorie restriction alleviates the age-related decrease in neural progenitor cell division in the aging brain . European Journal of Neuroscience. 37. (12). p. 1987-1993.
(2013). Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders . Molecular Autism. 4. (1).
BOOK
Magistri, M., Velmeshev, D.(2017). Identification of long noncoding RNAs associated to human disease susceptibility . Methods in Molecular Biology. 1543. p. 197-208.
Pastori, C., Velmeshev, D., Peschansky, V.J.(2017). Deep-RACE: Comprehensive search for novel ncRNAs associated to a specific locus . Methods in Molecular Biology. 1543. p. 129-143.
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