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USD 25 /hr

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☆☆☆☆☆

Hire Dr. Dhaval P.

India

USD 25 /hr

Protein Biochemist & Bioinformatician | Expert in Docking & Simulations, Structural Bioinformatics (12+ years of exp).

Profile Summary

I have 12+ years of experience in Bioinformatics, Biochemistry, Biophysics and Molecular Biology. I worked in both experimental as well as theoretical sciences. In our group, we desire to complement our theoretical research prediction with experimental results. I have completed numerous projects mainly focusing on gene cloning, protein expression and purification as well as small molecule discovery against protein with therapeutic interest.

Subject Matter Expertise

• ★ Molecular Modeling
• ★ Structural Biology
• ★ Bioinformatics
• ☆ Computational Biology
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Biophysics
• ☆ Genetic Engineering

Services

• Writing
• Research
• Data & AI
• Product Development

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Feasibility Study, Gap Analysis, Gray Literature Search, Systematic Literature Review

Data & AI Predictive Modeling, Statistical Analysis, Data Visualization, Big Data Analytics, Data Processing, Data Insights

Product Development Product Validation

Work Experience

Assistant Professor

Institute of Advanced Research

September 2017 - Present

PhD research scholar

The M S University of Baroda

September 2012 - August 2017

Technical Assistant

INDIAN INSTITUTE OF ADVANCED RESEARCH

November 2009 - September 2012

Education

PhD, Biochemistry

The Maharaja Sayajirao University of Baroda

September 2012 - March 2017

Masters (Bioinformatics)

Sardar Patel University

July 2007 - June 2009

Bacherlors (Bioinformatics)

Sardar Patel University

June 2004 - July 2007

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Dhaval Patel, Gurprit Bhardwaj, Mitul Vakani, Abhay Srivastava, Anju Pappachan, Prashant Murumkar, Hemal Shah, Rushabh Shah, Sarita Gupta(2021). Swertisin, a novel SGLT2 inhibitor, with improved glucose homeostasis for effective diabetes therapy . Archives of Biochemistry and Biophysics. 710. p. 108995. Elsevier {BV}

Dhaval Patel, Armi Chaudhari, Minal Chaudhari, Sapna Mahera, Zuber Saiyed, Neelam M. Nathani, Shantanu Shukla, Chirag Patel, Madhvi Joshi, Chaitanya G. Joshi(2021). In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1 . Informatics in Medicine Unlocked. 25. p. 100670. Elsevier {BV}

Dhaval Patel, Mohd Athar, P. C Jha(2020). Computational investigation of binding of chloroquinone and hydroxychloroquinone against PLPro of SARS-CoV-2 . Journal of Biomolecular Structure and Dynamics. p. 1--11. Informa {UK} Limited

Dhaval Patel, Abhilasha Sharma, Jaykant Vora, Sonam Sinha, Prakash C. Jha, Neeta Shrivastava(2020). Identification of natural inhibitors against prime targets of SARS-CoV-2 using molecular docking, molecular dynamics simulation and MM-PBSA approaches . Journal of Biomolecular Structure and Dynamics. p. 1--16. Informa {UK} Limited

(2019). Synthesis and Aggregation Studies of a Pyridothiazole-Based AIEE Probe and Its Application in Sensing Amyloid Fibrillation . ACS Applied Bio Materials.

Manhas, A., Patel, D., Lone, M.Y., Jha, P.C.(2019). Identification of natural compound inhibitors against PfDXR: A hybrid structure-based molecular modeling approach and molecular dynamics simulation studies . Journal of Cellular Biochemistry. 120. (9). p. 14531-14543.

Gour, N., Kshtriya, V., Gupta, S., Koshti, B., Singh, R., Patel, D., Joshi, K.B.(2019). Synthesis and Aggregation Studies of a Pyridothiazole-Based AIEE Probe and Its Application in Sensing Amyloid Fibrillation . ACS Applied Bio Materials. 2. (10). p. 4442-4455.

Patel, P., Parmar, K., Patel, D., Kumar, S., Trivedi, M., Das, M.(2018). Inhibition of amyloid fibril formation of lysozyme by ascorbic acid and a probable mechanism of action . International Journal of Biological Macromolecules. 114. p. 666-678.

Patel, Palak and Parmar, Krupali and Patel, Dhaval and Kumar, Suresh and Trivedi, Manan and Das, Mili(2018). Inhibition of amyloid fibril formation of lysozyme by ascorbic acid and a probable mechanism of action. International journal of biological macromolecules. 114. p. 666--678. Elsevier

Patel, B., Patel, D., Parmar, K., Chauhan, R., Singh, D.D., Pappachan, A.(2018). L. donovani XPRT: Molecular characterization and evaluation of inhibitors . Biochimica et Biophysica Acta - Proteins and Proteomics. 1866. (3). p. 426-441.

Patel, P., Parmar, K., Vyas, V.K., Patel, D., Das, M.(2017). Combined in silico approaches for the identification of novel inhibitors of human islet amyloid polypeptide (hIAPP) fibrillation . Journal of Molecular Graphics and Modelling. 77. p. 295-310.

Patel, Palak and Parmar, Krupali and Vyas, Vivek K and Patel, Dhaval and Das, Mili(2017). Combined in silico approaches for the identification of novel inhibitors of human islet amyloid polypeptide (hIAPP) fibrillation. Journal of Molecular Graphics and Modelling. 77. p. 295--310. Elsevier

Mansuri, Mohmmad Shoab and Laddha, Naresh C and Dwivedi, Mitesh and Patel, Dhaval and Alex, Tina and Singh, Mala and Singh, Desh D and Begum, Rasheedunnisa(2016). Genetic variations (Arg5Pro and Leu6Pro) modulate the structure and activity of GPX1 and genetic risk for vitiligo. Experimental dermatology. 25. (8). p. 654--657.

Shah, K.R., Patel, D.K., Pappachan, A., Prabha, C.R., Singh, D.D.(2016). Characterization of a Kunitz-type serine protease inhibitor from Solanum tuberosum having lectin activity . International Journal of Biological Macromolecules. 83. p. 259-269.

Patel, Dhaval K and Shah, Kunal R and Pappachan, Anju and Gupta, Sarita and Singh, Desh Deepak(2016). Cloning, expression and characterization of a mucin-binding GAPDH from Lactobacillus acidophilus. International journal of biological macromolecules. 91. p. 338--346. Elsevier

Patel, D.K., Shah, K.R., Pappachan, A., Gupta, S., Singh, D.D.(2016). Cloning, expression and characterization of a mucin-binding GAPDH from Lactobacillus acidophilus . International Journal of Biological Macromolecules. 91. p. 338-346.

Mansuri, M.S., Laddha, N.C., Dwivedi, M., Patel, D., Alex, T., Singh, M., Singh, D.D., Begum, R.(2016). Genetic variations (Arg5Pro and Leu6Pro) modulate the structure and activity of GPX1 and genetic risk for vitiligo . Experimental Dermatology. 25. (8). p. 654-657.

Kunal R. Shah, Dhaval K. Patel, Anju Pappachan, C. Ratna Prabha, Desh Deepak Singh(2015). Characterization of a Kunitz-type serine protease inhibitor from Solanum tuberosum having lectin activity. International Journal of Biological Macromolecules. 83. (February 2016). p. 259--269. ELSEVIER

Kaushal, Radhey Shyam and Mangukia, Naman and Patel, Dhaval and Pappachan, Anju and Singh, Desh DeepakUnraveling of a unique Hypothetical Protein having adhesin like property from Leishmania donovani spp.

OTHER

Dhaval Patel, Meet Parmar, Ritik Thumar, Bhumi Patel, Mohd Athar, Prakash C. Jha(2021). Structural Differences In 3C-like protease (Mpro) From SARS-CoV and SARS-CoV-2: Molecular Insights For Drug Repurposing Against COVID-19 Revealed by Molecular Dynamics Simulations . Cold Spring Harbor Laboratory

Dhaval Patel, Armi Chaudhari, Minal Chaudhari, Sapna Mahera, Zuber Saiyed, Neelam M. Nathani, Shantanu Shukla, Chirag Patel, Madhvi Joshi, Chaitanya G. Joshi (2020). In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and HNRNP-1 .

Dhaval Patel, Mohd Athar, Prakash C. Jha(2020). Exploring Ruthenium-based organometallic inhibitors against Plasmodium Calcium Dependent Kinase 2 (PfCDPK2): a combined ensemble docking, QM paramterization and molecular dynamics study . Cold Spring Harbor Laboratory

PREPRINT

(2019). Synthesis and self-assembly studies of a new AIEE probe and its application in sensing amyloid fibrillation . chemrxiv.