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Hire Dr. Daniela C.
Brazil
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Scientific Consulting & Writer | Literature review | Expert in Protein Chemistry and Purification methods
Profile Summary
Subject Matter Expertise
Services
Work Experience
Postdoctoral fellowship
Instituto Butantan
October 2017 - Present
Education
PhD in Science - Biotechnology
Universidade de São Paulo
August 2013 - September 2017
MSc in Laboratory Research in Public Health
Coordination for Disease Control of the Department of Health of the State of São Paulo
February 2011 - March 2013
Biology
Mackenzie Presbyterian University
August 2006 - July 2010
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Asega, A.F., Menezes, M.C., Trevisan-Silva, D., Cajado-Carvalho, D., Bertholim, L., Oliveira, A.K., Zelanis, A., Serrano, S.M.T.(2020). Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases . Scientific Reports. 10. (1).
Daniela Cajado Carvalho, Cristiane Castilho Fernandes da Silva, Roberto Tadashi Kodama, Douglas Mariano, Daniel Carvalho Pimenta, Bruno Duzzi, Alexandre Kazuo Kuniyoshi, Fernanda Portaro (2019). Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the <i>Tityus serrulatus</i> Venom . Toxins.
Cajado-Carvalho, D., Silva, C.C.F.D., Kodama, R.T., Mariano, D.O.C., Pimenta, D.C., Duzzi, B., Kuniyoshi, A.K., Portaro, F.V.(2019). Purification and biochemical characterization of tsms 3 and tsms 4: Neuropeptide-degrading metallopeptidases in the tityus serrulatus venom . Toxins. 11. (4).
Kuniyoshi, A.K., Kodama, R.T., Cajado-Carvalho, D., Iwai, L.K., Kitano, E., da Silva, C.C.F., Duzzi, B., Dias da Silva, W., Portaro, F.C.(2019). Experimental antivenom against serine proteases from the Bothrops jararaca venom obtained in mice, and its comparison with the antibothropic serum from the Butantan Institute . Toxicon. 169. p. 59-67.
Neto, E. B., Mariano, D. O. C., Freitas, L. A., Dorce, A. L. C., Martins, A. N., Pimenta, D. C., Portaro, F. C. V., Cajado-Carvalho, D., Dorce, V. A. C., Nencioni, A. L. A.(2018). Tb II-I, a Fraction Isolated from Tityus bahiensis Scorpion Venom, Alters Cytokines': Level and Induces Seizures When Intrahippocampally Injected in Rats . Toxins. 10. (6).
Neto, E.B., Mariano, D.O.C., Freitas, L.A., Dorce, A.L.C., Martins, A.N., Pimenta, D.C., Portaro, F.C.V., Cajado-Carvalho, D., Dorce, V.A.C., Nencioni, A.L.A.(2018). Tb ii-i, a fraction isolated from tityus bahiensis scorpion venom, alters cytokines’: Level and induces seizures when intrahippocampally injected in rats . Toxins. 10. (6).
Kuniyoshi, A.K., Kodama, R.T., Moraes, L.H.F., Duzzi, B., Iwai, L.K., Lima, I.F., Cajado-Carvalho, D., Portaro, F.V.(2017). In vitro cleavage of bioactive peptides by peptidases from Bothrops jararaca venom and its neutralization by bothropic antivenom produced by Butantan Institute: Major contribution of serine peptidases . Toxicon. 137. p. 114-119.
Cajado-Carvalho, D., Galvão, J., Kuniyoshi, A.K., Carneiro, P.D.S., Leme, A.F.P., Pauletti, B.A., Marengo, E.B., Portaro, F.V.(2017). Tityus serrulatus scorpion venom: In vitro tests and their correlation with in vivo lethal dose assay . Toxins. 9. (12).
Cajado-Carvalho, D., Galvao, J., Kuniyoshi, A. K., Carneiro, P. D., Leme, A. F. P., Pauletti, B. A., Marengo, E. B., Portaro, F. V.(2017). Tityus serrulatus Scorpion Venom: In Vitro Tests and Their Correlation with In Vivo Lethal Dose Assay . Toxins. 9. (12).
Kuniyoshi, A. K., Kodama, R. T., Moraes, L. H. F., Duzzi, B., Iwai, L. K., Lima, I. F., Cajado-Carvalho, D., Portaro, F. V.(2017). In vitro cleavage of bioactive peptides by peptidases from Bothrops jararaca venom and its neutralization by bothropic antivenom produced by Butantan Institute: Major contribution of serine peptidases . Toxicon. 137. p. 114-119.
Duzzi, B., Cajado-Caryalho, D., Kuniyoshi, A. K., Kodama, R. T., Gozzo, F. C., Fioramonte, M., Tambourgi, D. V., Portaro, F. V., Rioli, V.(2016). des-Arg(1) -Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom . Peptides. 80. p. 18-24.
Cajado-Carvalho, D., Kuniyoshi, A.K., Duzzi, B., Iwai, L.K., De Oliveira, Ú.C., De Azevedo, I.L.M.J., Kodama, R.T., Portaro, F.V.(2016). Insights into the hypertensive effects of tityus serrulatus scorpion venom: Purification of an angiotensin-converting enzyme-like peptidase . Toxins. 8. (12).
Cajado-Carvalho, D., Kuniyoshi, A. K., Duzzi, B., Iwai, L. K., de Oliveira, U. C., de Azevedo, Idmj, Kodama, R. T., Portaro, F. V.(2016). Insights into the Hypertensive Effects of Tityus serrulatus Scorpion Venom: Purification of an Angiotensin-Converting Enzyme-Like Peptidase . Toxins. 8. (12).
Duzzi, B., Cajado-Carvalho, D., Kuniyoshi, A.K., Kodama, R.T., Gozzo, F.C., Fioramonte, M., Tambourgi, D.V., Portaro, F.V., Rioli, V.(2016). [des-Arg<sup>1</sup>]-Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom . Peptides. 80. p. 18-24.
Kodama, R.T., Cajado-Carvalho, D., Kuniyoshi, A.K., Kitano, E.S., Tashima, A.K., Barna, B.F., Takakura, A.C., Serrano, S.M.T., Dias-Da-Silva, W., Tambourgi, D.V., et al.(2015). New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms . Biochimica et Biophysica Acta - General Subjects. 1850. (6). p. 1180-1187.
Kodama, R. T., Cajado-Carvalho, D., Kuniyoshi, A. K., Kitano, E. S., Tashima, A. K., Barna, B. F., Takakura, A. C., Serrano, S. M. T., Dias-Da-Silva, W., Tambourgi, D. V., et al.(2015). New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms . Biochimica Et Biophysica Acta-General Subjects. 1850. (6). p. 1180-1187.
Rodriguez, R. V., Dorce, V. A. C., de Freitas, L. A., Dorce, A. L. C., Lebrun, I., Sobral, A. C. M., Portaro, F. C. V., Kuniyoshi, A. K., Carvalho, D. C., Nencioni, A. L. A.(2015). Intrahippocampal injection of TsTX-I increases the levels of INF-gamma in the cerebral tissue but not the levels of glutamate . Toxicon. 103. p. 155-159.
Faria, M., Palomino, M., Cajado, D., Ferreira, A. K., Milene, M. C., Tashima, A., Pardanaud, L., Melo, R. L., Portaro, F., Serrano, S. M. T.(2014). Growth factor signaling in development and disease . Angiogenesis. 17. (1). p. 292.
Carvalho, D. C., Kuniyoshi, A. K., Kodama, R. T., Oliveira, A. K., Serrano, S. M. T., Tambourgi, D. V., Portaro, F. V.(2014). Neuropeptide Y Family-Degrading Metallopeptidases in the Tityus serrulatus Venom Partially Blocked by Commercial Antivenoms . Toxicological Sciences. 142. (2). p. 418-426.
Carvalho, D. C., Duzzi, B., Kuniyoshi, A. K., Fioramonte, M., Gozzo, F. C., Melo, R. L., Tambourgi, D. V., Rioli, V., Portaro, F. C.(2013). Insights into scorpion venom peptides: Alternative processing of beta-KTx propeptide from Tityus serrulatus venom results in a new naturally occurring thimet oligopeptidase inhibitor . Peptides. 40. p. 30-33.
Venancio, E. J., Portaro, F. C. V., Kuniyoshi, A. K., Carvalho, D. C., Pidde-Queiroz, G., Tambourgi, D. V.(2013). Enzymatic properties of venoms from Brazilian scorpions of Tityus genus and the neutralisation potential of therapeutical antivenoms . Toxicon. 69. p. 180-190.
Kuniyoshi, A.K., Rocha, M., Cajado Carvalho, D., Juliano, M.A., Juliano Neto, L., Tambourgi, D.V., Portaro, F.C.V.(2012). Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom . Toxicon. 59. (1). p. 124-131.
Kuniyoshi, A. K., Rocha, M., Carvalho, D. C., Juliano, M. A., Neto, L. J., Tambourgi, D. V., Portaro, F. C. V.(2012). Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom . Toxicon. 59. (1). p. 124-131.
Venancio, E. J., Portaro, F. C. V., Kuniyoshi, A. K., Carvalho, D. C., Pidde-Queiroz, G., Tambourgi, D. V.(2012). Identification of a Dynorphin-Degrading Metallopeptidase Releasing Leu-Enkephalin in Brazilian Tityus spp. Scorpion Venoms . Toxicon. 60. (2). p. 182-183.
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