Profile Details

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Hire Dr. Damien T.

France

USD 200 /hr

Freelance scientific expert specialized in preclinical development - technical writer

Profile Summary

Scientist executive (PhD) and entrepreneur with extensive experience in biotech R&D. Deep technical and scientific expertise (15+ years) in neurodegenerative disorders (Parkinson’s disease, ALS, Alzheimer’s disease) with strong business and project management insights. Drug hunter with passion for building and translating projects from early exploratory up to clinical candidate validation. technical writer with demonstrated ability tosuccesfully publish articles and obtain grants

Subject Matter Expertise

• ★ Drug Discovery
• ★ Preclinical Research
• ★ Grant Writing
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Drug Design
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Biosafety Testing
• ☆ Microbiology Testing
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Drug Efficacy Testing
• ☆ Bioavailability
• ☆ Pharmaceutical Manufacturing
• ☆ Pharmaceutical Process Development
• ☆ Biologic & Biosimilar Manufacturing
• ☆ Immunotherapy
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Regulatory Writing
• ☆ CMC Documentation
• ☆ Nonclinical Study Documentation
• ☆ Medical Writing
• ☆ Medical Content Writing
• ☆ Healthcare Communications
• ☆ Research Summaries & Abstracts
• ☆ Investigational New Drug (IND) Application Writing
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Release Notes
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Spec Sheets
• ☆ Case Studies
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Language Translation
• ☆ Screenwriting
• ☆ Creative Writing
• ☆ Audio Transcription
• ☆ Speechwriting
• ☆ News Writing
• ☆ Course Content Writing

Services

• Writing

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Business & Legal Writing, Copywriting, Newswriting, Audio Transcription, General Proofreading & Editing, Translation

Work Experience

Chief Scientific Officer

ENCEFA

September 2015 - Present

Founder/CSO

ENCEFA

October 2015 - October 2023

Chief Project Manager

Pharnext

March 2014 - September 2015

Project manager

Pharnext

March 2014 - September 2015

Sientific consultant

Subventium

January 2011 - July 2013

Education

Université Pierre et Marie Curie

September 2007 - December 2010

PhD

Université Pierre et Marie Curie (Paris VI) - France

January 2007 - December 2010

M.Sc Biochemistry and Genetics

AGROCAMPUS OUEST

September 2004 - June 2007

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Damien Toulorge, Serge Guerreiro, Anne-Laure Privat, Laurence Bressac(2020). CD38 in Neurodegeneration and Neuroinflammation . Cells. 9. (2). p. 471. {MDPI} {AG}

Damien Toulorge and Anthony H. V. Schapira and Rodolphe Hajj(2016). Molecular changes in the postmortem parkinsonian brain . Journal of Neurochemistry. 139. p. 27--58. Wiley

Rodolphe Hajj and Aude Milet and Damien Toulorge and Nathalie Cholet and Julien Laffaire and Julie Foucquier and Sandra Robelet and Richard Mitry and Mickael Guedj and Serguei Nabirotchkin and Ilya Chumakov and Daniel Cohen(2015). Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease . Scientific Reports. 5. (1). Springer Science and Business Media {LLC}

Ilya Chumakov and Serguei Nabirotchkin and Nathalie Cholet and Aude Milet and Aur{\'{e}}lie Boucard and Damien Toulorge and Yannick Pereira and Esther Graudens and Sory Traor{\'{e}} and Julie Foucquier and Mickael Guedj and Emmanuel Vial and Noëlle Callizot and R{\'{e}}my Steinschneider and Tangui Maurice and Viviane Bertrand and Catherine Scart-Gr{\`{e}}s and Rodolphe Hajj and Daniel Cohen(2015). Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy . Scientific Reports. 5. (1). Springer Science and Business Media {LLC}

Patrick P. Michel and Damien Toulorge and Serge Guerreiro and Etienne C. Hirsch(2013). Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease . The FASEB Journal. 27. (9). p. 3414--3423. Wiley

Damien Toulorge and Serge Guerreiro and Audrey Hild and Uwe Maskos and Etienne C. Hirsch and Patrick P. Michel(2011). Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca 2+ . The FASEB Journal. 25. (8). p. 2563--2573. Wiley

Damien Toulorge and Serge Guerreiro and Etienne C. Hirsch and Patrick P. Michel(2010). KATP channel blockade protects midbrain dopamine neurons by repressing a glia-to-neuron signaling cascade that ultimately disrupts mitochondrial calcium homeostasis . Journal of Neurochemistry. 114. (2). p. 553--564. Wiley

Serge Guerreiro and Aur{\'{e}}lie Ponceau and Damien Toulorge and Elodie Martin and Daniel Alvarez-Fischer and Etienne C. Hirsch and Patrick P. Michel(2009). Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization . Journal of Neurochemistry. 109. (4). p. 1118--1128. Wiley

Serge Guerreiro and Damien Toulorge and Etienne Hirsch and Marc Marien and Pierre Sokoloff and Patrick P. Michel(2008). Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels . Molecular Pharmacology. 74. (4). p. 980--989. American Society for Pharmacology {\&} Experimental Therapeutics ({ASPET})