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Hire Daiane E.
Sweden

Life Science Consultant | Research

Profile Summary
Subject Matter Expertise
Services
Writing Clinical Trial Documentation, Medical Writing, General Proofreading & Editing
Research Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection
Work Experience

Postdoctoral Fellow

Linköping University

March 2023 - Present

Scientific Analyst

PreScouter Inc.

October 2022 - Present

Assistant Professor

Universidade Federal de Ouro Preto

November 2020 - Present

Postdoctoral fellow

Universidade Estadual de Campinas

February 2018 - October 2020

Education

PhD in Biochemistry

Universidade Federal de Santa Catarina

March 2013 - December 2016

Visiting scientist (Dresden Center for Regenerative Therapies )

TU Dresden

September 2015 - August 2016

MSc in Neuroscience

Universidade Federal de Santa Catarina

July 2011 - February 2013

BSc in Pharmacy and Biochemistry

Universidade Federal de Santa Catarina

March 2007 - June 2011

Certifications
Publications
JOURNAL ARTICLE
Daiane F. Engel, Licio A. Velloso (2022). The timeline of neuronal and glial alterations in experimental obesity . Neuropharmacology.
Priscilla Karla Fernandes Lopes, Daiane Fátima Engel, Natalia Oliveira Bertolini, Moisés Silvestre de Azevedo Martins, Chrystian Araujo Pereira, Licio Augusto Velloso, Sérgio Scherrer Thomasi, Rodrigo Ferreira de Moura(2021). Behavioral, neuroplasticity and metabolic effects of 7,8-dihydroxy-4-methylcoumarin associated with physical activity in mice . Metabolic Brain Disease. Springer Science and Business Media {LLC}
Lucas Zangerolamo and Carina Solon and Gabriela M. Soares and Daiane F. Engel and Licio A. Velloso and Antonio C. Boschero and Everardo M. Carneiro and Helena Cristina L. Barbosa(2021). Energy homeostasis deregulation is attenuated by TUDCA treatment in streptozotocin-induced Alzheimer’s disease mice model . Scientific Reports. 11. (1). Springer Science and Business Media {LLC}
Vanessa C. Bobbo and Daiane F. Engel and Carlos Poblete Jara and Natalia F. Mendes and Roberta Haddad-Tovolli and Thais P. Prado and Davi Sidarta-Oliveira and Joseane Morari and Licio A. Velloso and Eliana P. Araujo(2021). Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis . Journal of Neuroinflammation. 18. (1). Springer Science and Business Media {LLC}
Carlos Poblete Jara, Beatriz de Andrade Berti, Natália Ferreira Mendes, Daiane Fátima Engel, Ariane Maria Zanesco, Gabriela Freitas Pereira de Souza, Renan de Medeiros Bezerra, Julia de Toledo Bagatin, Silvya Stuchi Maria-Engler, Joseane Morari, et al. (2021). Glutamic acid promotes hair growth in mice . Scientific Reports.
Lucas Zangerolamo and Jean F. Vettorazzi and Carina Solon and Gabriela A. Bronczek and Daiane F. Engel and Mirian A. Kurauti and Gabriela M. Soares and Karina S. Rodrigues and L{\'{\i}}cio A. Velloso and Antonio C. Boschero and Everardo M. Carneiro and Helena C.L. Barbosa(2020). The bile acid TUDCA improves glucose metabolism in streptozotocin-induced Alzheimer’s disease mice model . Molecular and Cellular Endocrinology. p. 111116. Elsevier {BV}
(2020). High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr–/– Mice: Impact on Cognitive Function . Journal of Alzheimer's Disease.
Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Scientific Reports.
(2020). Mitochondrial NAD(P)+ Transhydrogenase is Unevenly Distributed in Different Brain Regions, and its Loss Causes Depressive-like Behavior and Motor Dysfunction in Mice . Neuroscience.
(2020). Neuroprotective effects of mirtazapine and imipramine and their effect in pro- and anti-apoptotic gene expression in human neuroblastoma cells . Pharmacological reports : PR.
(2020). Red wine consumption mitigates the cognitive impairments in low-density lipoprotein receptor knockout (LDLr-/-) mice . Nutritional neuroscience.
(2020). LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis . Journal of Alzheimer's disease : JAD.
(2019). Interleukin-17 acts in the hypothalamus reducing food intake . Brain, Behavior, and Immunity.
(2019). Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells . Molecular metabolism.
(2018). Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system . Redox Biology.
(2017). Duloxetine Protects Human Neuroblastoma Cells from Oxidative Stress-Induced Cell Death Through Akt/Nrf-2/HO-1 Pathway . Neurochemical research.
(2016). Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice . Molecular neurobiology.
(2016). Is there an association between hypercholesterolemia and depression? Behavioral evidence from the LDLr(-/-) mouse experimental model . Behavioural brain research.
(2016). Caffeine Mitigates the Locomotor Hyperactivity in Middle-aged Low-density Lipoprotein Receptor (LDLr)-Knockout Mice . CNS Neuroscience & Therapeutics.
(2015). Efficacy of Donepezil for Cognitive Impairments in Familial Hypercholesterolemia: Preclinical Proof of Concept . CNS Neuroscience & Therapeutics.
(2015). Succinobucol, a Lipid-Lowering Drug, Protects Against 3-Nitropropionic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Cells via Upregulation of Glutathione Levels and Glutamate Cysteine Ligase Activity . Molecular neurobiology.
(2014). β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway . Neuroscience.
(2013). Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event? . Journal of neural transmission (Vienna, Austria : 1996).
(2013). Chronic administration of duloxetine and mirtazapine downregulates proapoptotic proteins and upregulates neurotrophin gene expression in the hippocampus and cerebral cortex of mice . Journal of psychiatric research.
(2012). Folic acid prevents depressive-like behavior and hippocampal antioxidant imbalance induced by restraint stress in mice . Experimental neurology.
(2012). The role of the NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of duloxetine in the forced swimming test . Pharmacology, biochemistry, and behavior.
(2010). Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test . European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
OTHER
Carlos Poblete Jara, Beatriz de Andrade Berti, Natalia Ferreira Mendes, Daiane F. Engel, Ariane Maria Zanesco, Gabriela Freitas Souza, L&#237;cio Augusto Velloso, Eliana Pereira de Araujo(2020). Glutamic acid promotes hair growth in mice . Cold Spring Harbor Laboratory