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USD 35 /hr
Hire Dr. Cleber C.
United States
USD 35 /hr
Cheminformatician working on scientific writing, Computer-Aided Drug Design, and machine learning.
Profile Summary
Subject Matter Expertise
Services
Work Experience
Postdoctoral Research Associate
University of North Carolina at Chapel Hill
June 2019 - Present 
Research Scientist
InsiChem
March 2017 - June 2018
Education
PhD in Tropical Medicine and Public Health (Tropical Medicine and Public Health Institute)
Universidade Federal de Goiás
March 2014 - April 2018
Master's degree (Faculdade de Farmácia)
Universidade Federal de Goiás
March 2012 - March 2014
Bachelor of Pharmacy (Faculdade de Farmácia)
Universidade Federal de Goiás
March 2007 - December 2011
Certifications
- Certification details not provided.
Publications
OTHER
Cleber C. Melo-Filho, Tesia Bobrowski, Vinicius Alves, Daniel Korn, Scott S. Auerbach, Charles Schmitt, Eugene Muratov, Alexander Tropsha (2020). Computational Models Identify Several FDA Approved or Experimental Drugs as Putative Agents Against SARS-CoV-2 .
Cleber C. Melo-Filho, Tesia Bobrowski, Vinicius Alves, Daniel Korn, Scott S. Auerbach, Charles Schmitt, Eugene Muratov, Alexander Tropsha(2020). Computational Models Identify Several FDA Approved or Experimental Drugs as Putative Agents Against SARS-CoV-2 . American Chemical Society ({ACS})
JOURNAL ARTICLE
Bobrowski, T., Melo-Filho, C.C., Korn, D., Alves, V.M., Popov, K.I., Auerbach, S., Schmitt, C., Moorman, N.J., Muratov, E.N., Tropsha, A.(2020). Learning from history: do not flatten the curve of antiviral research! . Drug Discovery Today.
Alves, V.M., Bobrowski, T., Melo-Filho, C.C., Korn, D., Auerbach, S., Schmitt, C., Muratov, E.N., Tropsha, A.(2020). QSAR Modeling of SARS-CoV M<sup>pro</sup> Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing against SARS-CoV-2 . Molecular Informatics.
Cleber C. Melo-Filho, Rodolpho C. Braga, Eugene N. Muratov, Caio Haddad Franco, Carolina B. Moraes, Lucio H. Freitas-Junior, Carolina Horta Andrade(2019). Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening . European Journal of Medicinal Chemistry. 163. p. 649--659. Elsevier {BV}
Melo-Filho, C.C., Braga, R.C., Muratov, E.N., Franco, C.H., Moraes, C.B., Freitas-Junior, L.H., Andrade, C.H.(2019). Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening . European Journal of Medicinal Chemistry. 163. p. 649-659.
Andrade, C.H., Neves, B.J., Melo-Filho, C.C., Rodrigues, J., Silva, D.C., Braga, R.C., Cravo, P.V.L.(2019). In silico chemogenomics drug repositioning strategies for neglected tropical diseases . Current Medicinal Chemistry. 26. (23). p. 4355-4379.
Melina Mottin, Joyce Villa Verde Bastos Borba, Cleber Camilo Melo-Filho, Bruno Junior Neves, Eugene Muratov, Pedro Henrique Monteiro Torres, Rodolpho Campos Braga, Alexander Perryman, Sean Ekins, Carolina Horta Andrade(2018). Computational drug discovery for the Zika virus . Brazilian Journal of Pharmaceutical Sciences. 54. (spe). {FapUNIFESP} ({SciELO})
Cleber C. Melo-Filho, Bruno J. Neves, Rodolpho C. Braga, José Teófilo Moreira-Filho, Eugene N. Muratov, Carolina Horta Andrade(2018). QSAR-Based Virtual Screening: Advances and Applications in Drug Discovery . Frontiers in Pharmacology. 9. Frontiers Media {SA}
Silva LC, Neves BJ, Gomes MN, Melo-Filho CC, Soares CM, Andrade CH, Pereira M(2018). Computer-aided identification of novel anti-paracoccidioidomycosis compounds . Future microbiology.
Daiane Dias Ferreira, Juliana Tonini Mesquita, Thais Alves da Costa Silva, Maiara Maria Romanelli, Denise da Gama Jaen Batista, Cristiane França da Silva, Aline Nefertiti Silva da Gama, Bruno Junior Neves, Cleber Camilo Melo-Filho, Maria de Nazare Correia Soeiro, et al.(2018). Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study . Journal of Venomous Animals and Toxins including Tropical Diseases. 24. (1). Springer Nature America, Inc
Carolina Horta Andrade, Bruno Junior Neves, Cleber Camilo Melo-Filho, Juliana Rodrigues, Diego Cabral Silva, Rodolpho Campos Braga, Pedro Vitor Lemos Cravo(2018). In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases . Current Medicinal Chemistry. 25. Bentham Science Publishers Ltd.
Cleber C. Melo-Filho, Marilia N. N. Lima, Gustavo C. Cassiano, Bruno J. Neves, Vinicius M. Alves, Rodolpho C. Braga, Pedro V. L. Cravo, Eugene N. Muratov, Juliana Calit, Daniel Y. Bargieri, et al.(2018). QSAR-Driven Design and Discovery of Novel Compounds With Antiplasmodial and Transmission Blocking Activities . Frontiers in Pharmacology. 9. Frontiers Media {SA}
Neves, B.J., Braga, R.C., Melo-Filho, C.C., Moreira-Filho, J.T., Muratov, E.N., Andrade, C.H.(2018). QSAR-based virtual screening: Advances and applications in drug discovery . Frontiers in Pharmacology. 9. (NOV).
Lima, M.N.N., Melo-Filho, C.C., Cassiano, G.C., Neves, B.J., Alves, V.M., Braga, R.C., Cravo, P.V., Muratov, E.N., Calit, J., Bargieri, D.Y., et al.(2018). QSAR-driven design and discovery of novel compounds with antiplasmodial and transmission blocking activities . Frontiers in Pharmacology. 9. (MAR).
Ferreira, D.D., Mesquita, J.T., Da Costa Silva, T.A., Romanelli, M.M., Da Gama Jaen Batista, D., Da Silva, C.F., Da Gama, A.N.S., Neves, B.J., Melo-Filho, C.C., Correia Soeiro, M.D.N., et al.(2018). Efficacy of sertraline against Trypanosoma cruzi: An in vitro and in silico study . Journal of Venomous Animals and Toxins Including Tropical Diseases. 24. (1).
Silva, L.C., Neves, B.J., Gomes, M.N., Melo-Filho, C.C., Soares, C.M.A., Andrade, C.H., Pereira, M.(2018). Computer-aided identification of novel anti-paracoccidioidomycosis compounds . Future Microbiology. 13. (13). p. 1523-1535.
Mottin, M., Borba, J.V.V.B., Melo-Filho, C.C., Neves, B.J., Muratov, E., Torres, P.H.M., Braga, R.C., Perryman, A., Ekins, S., Andrade, C.H.(2018). Computational drug discovery for the Zika virus . Brazilian Journal of Pharmaceutical Sciences. 54. (Special Issue).
Gomes, M.N., Alcântara, L.M., Neves, B.J., Melo-Filho, C.C., Freitas-Junior, L.H., Moraes, C.B., Ma, R., Franzblau, S.G., Muratov, E., Andrade, C.H.(2017). Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum . Bioorganic and Medicinal Chemistry Letters. 27. (11).
Neves, B.J., Dantas, R.F., Senger, M.R., Melo-Filho, C.C., Valente, W.C.G., De Almeida, A.C.M., Rezende-Neto, J.M., Lima, E.F.C., Paveley, R., Furnham, N., et al.(2016). Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening . Journal of Medicinal Chemistry. 59. (15). p. 7075-7088.
Melo-Filho, C.C., Dantas, R.F., Braga, R.C., Neves, B.J., Senger, M.R., Valente, W.C.G., Rezende-Neto, J.M., Chaves, W.T., Muratov, E.N., Paveley, R.A., et al.(2016). QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni . Journal of Chemical Information and Modeling. 56. (7). p. 1357-1372.
Melo-Filho, C.C., Braga, R.C., Andrade, C.H.(2014). 3D-QSAR Approaches in Drug Design: Perspectives to Generate Reliable CoMFA Models . Current Computer-Aided Drug Design. 10. (2). p. 148-159.
Melo-Filho, C.C., Braga, R.C., Andrade, C.H.(2014). Advances in methods for predicting phase i metabolism of polyphenols . Current Drug Metabolism. 15. (1). p. 120-126.
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