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Hire Dr. Chiara M.

Italy

USD 10 /hr

Biomedical scientist | Expert in virology and immunology. Editor with 10+ y of experience in academic research

Profile Summary

My fields of expertise are virology and immunology. With a solid background in biomedical research, extensive publication experience and grant writing, I have been reviewing and editing scientific manuscripts and grant applications, both professionally and independently, for more than ten years. I find it highly rewarding and I truly enjoy it. After earning a PhD in Medical Genetics I carried out postdoctoral research in Israel at the Weizmann Institute of Science, where I specialized in immunogenomics. Then, as Maître Assistante at the University of Geneva (Switzerland), I coordinated interdisciplinary and international research projects on influenza and SARS-CoV-2, contributing to the preparation of competitive funding applications. These roles strengthened my ability to critically evaluate scientific excellence, project feasibility and alignment with funding priorities. My publication record includes over 30 peer-reviewed articles published in leading journals including Science, Nature Immunology, and Cell. Currently, at the Functional Genomics Research Center at the Human Technopole (Milan, Italy), I continue to support proposal development and collaborative initiatives. In parallel, I review manuscripts for several journals, such as Archives of Microbiology, Scientific Reports, Antiviral research, Frontiers in Immunology, Virology Journal and Journal of Nanobiotechnology,

Subject Matter Expertise

• ☆ Microbiology
• ☆ Virology
• ☆ Coronaviruses
• ☆ Molecular Virology
• ☆ Microbiological Assays
• ☆ Molecular Biology
• ☆ Omics
• ☆ Genomics
• ☆ Next Generation Sequencing (NGS)
• ☆ Cell Biology
• ☆ Gene Regulation
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Pulmonology/Respiratory Disease
• ☆ Influenza

Services

• Writing
• Research
• Consulting

Writing General Proofreading & Editing

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

Work Experience

Lab Manager of the Functional Genomics Research Center

Fondazione Human technopole

January 2022 - Present

Human Technopole

2022 - Present

maître-assistant

University of Geneva

October 2018 - January 2022

Postdoctorate Researcher

Weizmann Institute of Science

April 2013 - October 2018

Education

master degree in Medical Biotechnology

Università degli studi di Napoli Federico II

January 2010 - April 2013

Certifications

• PhD in Production & Safety of Foods of Animal Origin

  Università degli studi di Napoli Federico II

  January 2026 - Present

Publications

JOURNAL ARTICLE

Chiara Medaglia, Clément Fage, Sheryline Loison, Arnaud Charles-Antoine Zwygart, Romain Poli, Stéphane Rosset, Mathieu Hubert, Patricia Suter-Boquete, Oscar Vadas, Song Huang, et al. (2025). Influenza A(H1N1)pdm09 virus resistance to baloxavir, oseltamivir and sialic acid mimetics in single and dual therapies: Insights from human airway epithelia and murine models . Antiviral Research.

Chiara Medaglia, Paola Cuomo, Angela Casillo, Antonio Gentile, Carmine Fruggiero, Maria Michela Corsaro, Rosanna Capparelli (2024). Phage-resistance alters Lipid A reactogenicity: a new strategy for LPS-based conjugate vaccines against Salmonella Rissen . Frontiers in Immunology.

Chiara Medaglia, Arnaud Charles‐Antoine Zwygart, Yong Zhu, E. Bart Tarbet, Westover Jonna, Clément Fage, Didier Le Roy, Thierry Roger, Sophie Clément, Samuel Constant, et al. (2024). Development of Broad‐Spectrum β‐Cyclodextrins‐Based Nanomaterials Against Influenza Viruses . Journal of Medical Virology.

Chiara Medaglia, Antonius Armanious, Heyun Wang, Peter A. Alpert, Mohammad Peydayesh, Arnaud Charles-Antoine Zwygart, Christian Gübeli, Stephan Handschin, Sreenath Bolisetty, Markus Ammann, et al. (2023). Trapping virus-loaded aerosols using granular material composed of protein nanofibrils and iron oxyhydroxides nanoparticles . Frontiers in Soft Matter.

An anti-influenza combined therapy assessed by single cell RNA-sequencing <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Communications Biology.

Chiara Medaglia, Paola Cuomo, Ivana Allocca, Angela Michela Immacolata Montone, Fabrizia Guerra, Serena Cabaro, Ernesto Mollo, Daniela Eletto, Marina Papaianni, Rosanna Capparelli (2021). Caulerpin Mitigates Helicobacter pylori-Induced Inflammation via Formyl Peptide Receptors . International Journal of Molecular Sciences.

Chiara Medaglia, Valeria Cagno, Andreas Cerny, Thomas Cerny, Arnaud Charles-Antoine Zwygart, Erich Cerny, Caroline Tapparel (2021). Methylene Blue has a potent antiviral activity against SARS-CoV-2 and H1N1 influenza virus in the absence of UV-activation in vitro . Scientific Reports.

Chiara Medaglia, Arnaud Charles-Antoine Zwygart, Paulo Jacob Silva, Samuel Constant, Song Huang, Francesco Stellacci, Caroline Tapparel (2021). Interferon Lambda Delays the Emergence of Influenza Virus Resistance to Oseltamivir . Microorganisms.

Chiara Medaglia, Paola Cuomo, Marina Papaianni, Rosanna Capparelli (2021). The Role of Formyl Peptide Receptors in Permanent and Low-Grade Inflammation: Helicobacter pylori Infection as a Model . International Journal of Molecular Sciences.

Chiara Medaglia, Ozgun Kocabiyik, Valeria Cagno, Paulo Jacob Silva, Yong Zhu, Laura Sedano, Yoshita Bhide, Joelle Mettier, Bruno Da Costa, Samuel Constant, et al. (2021). Non‐Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo . Advanced Science.

Chiara Medaglia, Valeria Cagno, Matteo Gasbarri, Diana Gomes, Sophie Clement, Francesco Stellacci, Caroline Tapparel (2020). Sulfonated Nanomaterials with Broad-Spectrum Antiviral Activity Extending beyond Heparan Sulfate-Dependent Viruses . Antimicrobial Agents and Chemotherapy.

Chiara Medaglia, Paola Cuomo, Marina Papaianni, Clementina Sansone, Antonio Iannelli, Domenico Iannelli, Debora Paris, Andrea Motta, Rosanna Capparelli (2020). An In Vitro Model to Investigate the Role of Helicobacter pylori in Type 2 Diabetes, Obesity, Alzheimer’s Disease and Cardiometabolic Disease . International Journal of Molecular Sciences.

Chiara Medaglia, Andrea Fulgione, Marina Papaianni, Paola Cuomo, Debora Paris, Marco Romano, Concetta Tuccillo, Letizia Palomba, Massimiliano De Seta, Nicolino Esposito, et al. (2020). Interaction between MyD88, TIRAP and IL1RL1 against Helicobacter pylori infection . Scientific Reports.

Chiara Medaglia, Paola Cuomo, Marina Papaianni, Andrea Fulgione, Fabrizia Guerra, Rosanna Capparelli (2020). An Innovative Approach to Control H. pylori-Induced Persistent Inflammation and Colonization . Microorganisms.

Chiara Medaglia, Pierre Bost, Amir Giladi, Yang Liu, Yanis Bendjelal, Gang Xu, Eyal David, Ronnie Blecher-Gonen, Merav Cohen, Hanjie Li, et al. (2020). Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients . Cell.

Chiara Medaglia, Amir Giladi, Lisa Katharina Wagner, Hanjie Li, Dorothea D&#246;rr, Franziska Paul, Anat Shemer, Steffen Jung, Simon Yona, Matthias Mack, et al. (2020). Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation . Nature Immunology.

Chiara Medaglia, Amir Giladi, Merav Cohen, Yael Baran, Baoguo Li, Mor Zada, Pierre Bost, Ronnie Blecher-Gonen, Tomer-Meir Salame, Johannes U. Mayer, et al. (2020). Dissecting cellular crosstalk by sequencing physically interacting cells . Nature Biotechnology.

Chiara Medaglia, Marco De Giovanni, Valeria Cutillo, Amir Giladi, Eleonora Sala, Carmela G. Maganuco, Pietro Di Lucia, Elisa Bono, Claudia Cristofani, Eleonora Consolo, et al. (2020). Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells . Nature Immunology.

Keren Bahar Halpern, Rom Shenhav, Hassan Massalha, Beata Toth, Adi Egozi, Efi E Massasa, Chiara Medgalia, Eyal David, Amir Giladi, Andreas E Moor, et al. (2018). Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells . Nature Biotechnology.

Chiara Medaglia, Felice Contaldi, Federico Capuano, Andrea Fulgione, Riccardo Aiese Cigliano, Walter Sanseverino, Domenico Iannelli, Rosanna Capparelli (2018). Author Correction: The hypothesis that Helicobacter pylori predisposes to Alzheimer’s disease is biologically plausible . Scientific Reports.

Chiara Medaglia, Amir Giladi, Liat Stoler-Barak, Marco De Giovanni, Tomer Meir Salame, Adi Biram, Eyal David, Hanjie Li, Matteo Iannacone, Ziv Shulman, et al.(2017). Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq . Science. 358. (6370). p. 1622--1626. American Association for the Advancement of Science ({AAAS})

Chiara Medaglia, Yonit Lavin, Soma Kobayashi, Andrew Leader, El-ad David Amir, Naama Elefant, Camille Bigenwald, Romain Remark, Robert Sweeney, Christian D. Becker, et al. (2017). Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses . Cell.

Chiara Medaglia, Aya Ludin, Shiri Gur-Cohen, Karin Golan, Kerstin B. Kaufmann, Tomer Itkin, Xin-Jiang Lu, Guy Ledergor, Orit Kollet, Tsvee Lapidot (2014). Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment . Antioxidants &amp; Redox Signaling.

Chiara Medaglia, Pasqualino De Antonellis, Marianeve Carotenuto, Jonathan Vandenbussche, Gennaro De Vita, Veronica Ferrucci, Iolanda Boffa, Alessandra Galiero, Sarah Di Somma, Daniela Magliulo, et al. (2014). Early Targets of miR-34a in Neuroblastoma . Molecular &amp; Cellular Proteomics.

R Capparelli, F De Chiara, A Di Matteo, C Medaglia, D Iannelli (2013). The MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis . Genes &amp; Immunity.

O Kollet, Y Vagima, G D&#39;Uva, K Golan, J Canaani, T Itkin, S Gur-Cohen, A Kalinkovich, G Caglio, C Medaglia, et al. (2013). Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors . Leukemia.

Chiara Medaglia, Rosanna Capparelli, Francesco De Chiara, Nunzia Nocerino, Rosa Di Costanzo, Luigi Ramunno, Federico Capuano, Francesco Casalinuovo, Antonio Di Matteo, Domenico Iannelli (2013). Heterozygosity at the A625C Polymorphic Site of the MyD88 Gene Is Associated with Mycobacterium bovis Infection in Cattle . Infection and Immunity.

Chiara Medaglia, Rosanna Capparelli, Nunzia Nocerino, Giuseppe Blaiotta, Patrizia Bonelli, Domenico Iannelli (2011). The Staphylococcus aureus Peptidoglycan Protects Mice against the Pathogen and Eradicates Experimentally Induced Infection . PLoS ONE.

Chiara Medaglia, Pasqualino de Antonellis, Emilio Cusanelli, Immacolata Andolfo, Lucia Liguori, Gennaro De Vita, Marianeve Carotenuto, Annamaria Bello, Fabio Formiggini, Aldo Galeone, et al. (2011). MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma . PLoS ONE.

Chiara Medaglia, Rosanna Capparelli, Nunzia Nocerino, Rosa Lanzetta, Alba Silipo, Angela Amoresano, Chiara Giangrande, Karsten Becker, Giuseppe Blaiotta, Antonio Evidente, et al. (2010). Bacteriophage-Resistant Staphylococcus aureus Mutant Confers Broad Immunity against Staphylococcal Infection in Mice . PLoS ONE.

Medaglia Chiara, Rosanna Capparelli, Nunzia Nocerino, Marco Iannaccone, Danilo Ercolini, Marianna Parlato, Domenico Iannelli (2010). Bacteriophage Therapy of<i>Salmonella enterica:</i>A Fresh Appraisal of Bacteriophage Therapy . The Journal of Infectious Diseases.

Chiara Medaglia, Rosanna Capparelli, Marco Iannaccone, Daniela Palumbo, Emilio Moscariello, Alfredo Russo, Domenico Iannelli (2009). Role Played by Human Mannose-Binding Lectin Polymorphisms in Pulmonary Tuberculosis . Journal of Infectious Diseases.

R. Brun, C. Urraro, C. Medaglia, V. Russo, G. Borzacchiello, F. Roperto, S. Roperto (2008). Lymphoepithelioma-like Carcinoma of the Urinary Bladder in a Cow Associated with Bovine Papillomavirus Type-2 . Journal of Comparative Pathology.