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USD 65 /hr

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Hire Dr. Carmela G.

Spain

USD 65 /hr

Experienced Postdoctoral Researcher with a demonstrated history of working experience in Biochemistry

Profile Summary

Skilled in molecular biology, biotechnology, protein purification, PCR, cloning and CRISPR biology. Strong research professional with a PhD focused in Biochemistry from Universidad Autónoma de Madrid and postdoctoral experience at the University of Zurich.

Subject Matter Expertise

• ★ Molecular Biology
• ☆ Microbiology
• ☆ Biochemistry

Services

• Writing
• Research
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Data Processing, Data Insights

Product Development Formulation, Product Validation, Concept Development

Work Experience

Scientific Advisor

-

March 2021 - Present

Instructor

LinkedIn Learning

March 2020 - Present

Poscaster

Emilcar FM

March 2017 - Present

Staff Scientist

Department of Biochemistry, University of Zürich

January 2020 - December 2020

Postdoctoral Researcher

Department of Biochemistry, University of Zürich

February 2014 - January 2020

PhD student

Universidad Autónoma de Madrid

October 2010 - December 2013

Education

PhD, Biochemistry

Universidad Autonoma de Madrid

September 2010 - October 2013

MSc Molecular Medicine

Universidad de Santiago de Compostela

September 2008 - July 2010

BSc Biology

Universidad de Santiago de Compostela

September 2003 - July 2008

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Carmela Garcia-Doval, Frank Schwede, Christian Berk, Jakob T. Rostøl, Ole Niewoehner, Oliver Tejero, Jonathan Hall, Luciano A. Marraffini, Martin Jinek(2020). Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6 . Nature Communications. 11. (1). Springer Science and Business Media {LLC}

Carmela Garcia-Doval, Martin Jinek(2017). Molecular architectures and mechanisms of Class 2 CRISPR-associated nucleases . Current Opinion in Structural Biology. 47. p. 157--166. Elsevier {BV}

Niewoehner, O., Garcia-Doval, C., Rostøl, J.T., Berk, C., Schwede, F., Bigler, L., Hall, J., Marraffini, L.A., Jinek, M.(2017). Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers . Nature. 548. (7669). p. 543-548.

González-García, V.A., Pulido-Cid, M., Garcia-Doval, C., Bocanegra, R., Van Raaij, M.J., Martín-Benito, J., Cuervo, A., Carrascosa, J.L.(2015). Conformational changes leading to T7 DNA delivery upon interaction with the bacterial receptor . Journal of Biological Chemistry. 290. (16). p. 10038-10044.

Garciadoval, C., Castón, J.R., Luque, D., Granell, M., Otero, J.M., Llamas-Saiz, A.L., Renouard, M., Boulanger, P., van Raaij, M.J.(2015). Structure of the receptor-binding carboxy-terminal domain of the bacteriophage T5 L-shaped tail fibre with and without its intra-molecular chaperone . Viruses. 7. (12). p. 6424-6440.

Ares, P., Garcia-Doval, C., Llauró, A., Gómez-Herrero, J., Van Raaij, M.J., De Pablo, P.J.(2014). Interplay between the mechanics of bacteriophage fibers and the strength of virus-host links . Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 89. (5).

Kryshtafovych, A., Moult, J., Bales, P., Bazan, J.F., Biasini, M., Burgin, A., Chen, C., Cochran, F.V., Craig, T.K., Das, R., et al.(2014). Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th critical assessment of techniques for protein structure prediction experiment CASP10 . Proteins: Structure, Function and Bioinformatics. 82. (SUPPL.2). p. 26-42.

Sanz-Gaitero, M., Keary, R., Garcia-Doval, C., Coffey, A., Van Raaij, M.J.(2014). Crystal structure of the lytic CHAP<inf>K</inf>domain of the endolysin LysK from Staphylococcus aureus bacteriophage K . Virology Journal. 11. (1).

Granell, M., Namura, M., Alvira, S., Garcia-Doval, C., Singh, A.K., Gutsche, I., Van Raaij, M.J., Kanamaru, S.(2014). Crystallization of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34 . Acta Crystallographica Section F:Structural Biology Communications. 70. (7). p. 970-975.

Cuervo, A., Pulido-Cid, M., Chagoyen, M., Arranz, R., González-García, V.A., Garcia-Doval, C., Castón, J.R., Valpuesta, J.M., Van Raaij, M.J., Martín-Benito, J., et al.(2013). Structural characterization of the bacteriophage T7 tail machinery . Journal of Biological Chemistry. 288. (36). p. 26290-26299.

Garcia-Doval, C., van Raaij, M.J.(2013). Bacteriophage receptor recognition and nucleic acid transfer . Sub-cellular biochemistry. 68. p. 489-518.

Blanco, B., Prado, V., Lence, E., Otero, J.M., Garcia-Doval, C., Van Raaij, M.J., Llamas-Saiz, A.L., Lamb, H., Hawkins, A.R., González-Bello, C.(2013). Mycobacterium tuberculosis shikimate kinase inhibitors: Design and simulation studies of the catalytic turnover . Journal of the American Chemical Society. 135. (33). p. 12366-12376.

Garcia-Doval, C., Luque, D., Castón, J.R., Boulanger, P., Van Raaij, M.J.(2013). Crystallization of the C-terminal domain of the bacteriophage T5 L-shaped fibre . Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 69. (12). p. 1363-1367.

Sanz-Gaitero, M., Keary, R., Garcia-Doval, C., Coffey, A., Van Raaij, M.J.(2013). Crystallization of the CHAP domain of the endolysin from staphylococcus aureus bacteriophage K . Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 69. (12). p. 1393-1396.

Garcia-Doval, C., Van Raaij, M.J.(2012). Structure of the receptor-binding carboxy-terminal domain of bacteriophage T7 tail fibers . Proceedings of the National Academy of Sciences of the United States of America. 109. (24). p. 9390-9395.

Garcia-Doval, C., Van Raaij, M.J.(2012). Crystallization of the C-terminal domain of the bacteriophage T7 fibre protein gp17 . Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 68. (2). p. 166-171.

Bartual, S.G., Otero, J.M., Garcia-Doval, C., Llamas-Saiz, A.L., Kahn, R., Fox, G.C., Van Raaij, M.J.(2010). Structure of the bacteriophage T4 long tail fiber receptor-binding tip . Proceedings of the National Academy of Sciences of the United States of America. 107. (47). p. 20287-20292.

Galan Bartual, S., Garcia-Doval, C., Alonso, J., Schoehn, G., van Raaij, M.J.(2010). Two-chaperone assisted soluble expression and purification of the bacteriophage T4 long tail fibre protein gp37 . Protein Expression and Purification. 70. (1). p. 116-121.

OTHER

Carmela Garcia-Doval, Frank Schwede, Christian Berk, Jakob T. Rostøl, Ole Niewoehner, Oliver Tejero, Jonathan Hall, Luciano A. Marraffini, Martin Jinek(2020). Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6 . Cold Spring Harbor Laboratory