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Hire Dr. Binod K.

United States

USD 50 /hr

Senior scientist with 16+ years of virology research and scientific communications

Profile Summary

Molecular Virologist with 16+ years of extensive research experience in the area of virus-host interactions, innate immunity, inflammation, viral diagnostics and development of antiviral drugs and strategies against emerging viral illnesses. I have proven expertise in development of Virus-like particle (VLP) based vaccine candidates for BSL-3 and BSL4 viral pathogens (SARS-CoV2 and Nipah Virus). Experienced in development of cell based as well as cell free assays for screening virus neutralizing antibodies and antiviral drugs. Have excellent track record of 50+ scientific publications in elite journals.

Subject Matter Expertise

• ★ Virology
• ★ Cell-Based Assays
• ★ Cell Signaling Pathways
• ☆ Microbiology
• ☆ Coronaviruses
• ☆ Molecular Virology
• ☆ Microbiological Assays
• ☆ Zoology
• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Molecular Biology
• ☆ PCR
• ☆ Cell Biology
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Surface Receptors
• ☆ Drug Development
• ☆ Vaccine Development
• ☆ Infectious Disease
• ☆ Pulmonology/Respiratory Disease
• ☆ Severe Acute Respiratory Syndrome (SARS)
• ☆ Influenza
• ☆ Public Health
• ☆ Epidemiology

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing, General Proofreading & Editing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Work Experience

Principal Scientist E2

Institute of Advanced Virology

December 2021 - Present

Research Associate

Loyola University Chicago

October 2019 - December 2021

Senior Research Associate

Rosalind Franklin University of Medicine and Science Chicago Medical School

September 2016 - September 2019

Post-Doctoral Research Associate

Rosalind Franklin University of Medicine and Science

September 2014 - September 2016

Post-Doctoral Researcher

Vallabhbhai Patel Chest Institute, University of Delhi

August 2013 - August 2014

Education

PhD (Department of Respiratory Virology)

Vallabhbhai Patel Chest Institute, University of Delhi

August 2009 - March 2014

Master of Science (Department of Biochemistry)

Bundelkhand University Faculty of Science

July 2004 - July 2006

Bachelor of Science (Zoology)

University of Delhi

July 2001 - May 2004

Certifications

• Ethics Review of Health Research

  NIE & Indian Council of Medical Research

  May 2022 - Present

• Scientific Writing in Health Research

  NIE & Indian Council of Medical Research

  May 2022 - Present

Publications

JOURNAL ARTICLE

Binod Kumar, Akshaya Ramachandran, Gulam Waris, David Everly, Benjamin W. Neuman(2021). Deubiquitination and Activation of the NLRP3 Inflammasome by UCHL5 in HCV-Infected Cells . Microbiology Spectrum. 9. (1). American Society for Microbiology

Binod Kumar, Enya Qing, Tom Kicmal, Grant M. Hawkins, Emily Timm, Stanley Perlman, Tom Gallagher, Anne Moscona(2021). Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains . mBio. 12. (4). American Society for Microbiology

Binod Kumar, Grant M. Hawkins, Tom Kicmal, Enya Qing, Emily Timm, Tom Gallagher(2021). Assembly and Entry of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2): Evaluation Using Virus-Like Particles . Cells. 10. (4). p. 853. {MDPI} {AG}

Binod Kumar, Grant M. Hawkins, Tom Kicmal, Enya Qing, Emily Timm, Tom Gallagher (2021). Assembly and Entry of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2): Evaluation Using Virus-Like Particles . Cells.

Binod Kumar, Mohanan Valiya Veettil, Gayathri Krishna, Arunava Roy, Anandita Ghosh, Dipanjan Dutta, Sayan Chakraborty, Thoppil Raveendran Anju, Neelam Sharma-Walia, Bala Chandran, et al.(2020). Kaposi’s Sarcoma-Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells . Journal of Virology. 94. (8). American Society for Microbiology

(2019). IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP . eLife.

Binod Kumar, Arunava Roy, Kumari Asha, Neelam Sharma-Walia, Mairaj Ahmed Ansari, Bala Chandran, Jae U. Jung(2019). HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi’s Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity . Journal of Virology. 93. (9). American Society for Microbiology

Binod Kumar, Kumari Asha (2019). Emerging Influenza D Virus Threat: What We Know so Far! . Journal of Clinical Medicine.

Binod Kumar, Kumari Asha (2019). Emerging Influenza D Virus Threat: What We Know so Far! . Journal of Clinical Medicine.

Binod Kumar, Kumari Asha, Prashant Kumar, Melvin Sanicas, Clement Meseko, Madhu Khanna (2018). Advancements in Nucleic Acid Based Therapeutics against Respiratory Viral Infections . Journal of Clinical Medicine.

Binod Kumar, Kumari Asha, Prashant Kumar, Melvin Sanicas, Clement A. Meseko, Madhu Khanna (2018). Advancements in Nucleic Acid Based Therapeutics against Respiratory Viral Infections . Journal of Clinical Medicine.

Binod Kumar, Kumari Asha, Madhu Khanna, Larance Ronsard, Clement Adebajo Meseko, Melvin Sanicas(2018). The emerging influenza virus threat: status and new prospects for its therapy and control . Archives of Virology. 163. (4). p. 831--844. Springer Science and Business Media {LLC}

(2018). Osteopontin regulates HCV replication and assembly via interaction with HCV proteins and lipid droplets and by binding to receptors, αVβ3 and CD44. Journal of Virology.

(2017). An Insight Into The Role of E3 ubiquitin Ligase c-Cbl, ESCRT Machinery and Host Cell Signaling in Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Entry and Trafficking. Journal of Virology.

(2017). Interferon-γ-inducible protein 16 (IFI16) is required for the maintenance of Epstein-Barr virus latency. Virology Journal.

(2017). Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction . Front Microbiology.

Binod Kumar, Bala Chandran(2016). KSHV Entry and Trafficking in Target Cells—Hijacking of Cell Signal Pathways, Actin and Membrane Dynamics . Viruses. 8. (12). p. 305. {MDPI} {AG}

(2016). KSHV Entry and Trafficking in Target Cells—Hijacking of Cell Signal Pathways, Actin and Membrane Dynamics . Viruses.

Binod Kumar, Dipanjan Dutta, Jawed Iqbal, Mairaj Ahmed Ansari, Arunava Roy, Leela Chikoti, Gina Pisano, Mohanan Valiya Veettil, Bala Chandran, Lindsey Hutt-Fletcher(2016). ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi’s Sarcoma-Associated Herpesvirus . PLOS Pathogens. 12. (10). p. e1005960. Public Library of Science ({PLoS})

Binod Kumar, Jawed Iqbal, Mairaj Ahmed Ansari, Dipanjan Dutta, Arunava Roy, Leela Chikoti, Gina Pisano, Sujoy Dutta, Shahrooz Vahedi, Mohanan Valiya Veettil, et al.(2016). Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses . PLOS Pathogens. 12. (10). p. e1005967. Public Library of Science ({PLoS})

Binod Kumar, Arunava Roy, Dipanjan Dutta, Jawed Iqbal, Gina Pisano, Olsi Gjyshi, Mairaj Ahmed Ansari, Bala Chandran, R. M. Longnecker(2016). Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency . Journal of Virology. 90. (19). p. 8822--8841. American Society for Microbiology

Binod Kumar, Mohanan Valiya Veettil, Mairaj Ahmed Ansari, Dipanjan Dutta, Jawed Iqbal, Olsi Gjyshi, Virginie Bottero, Bala Chandran, R. M. Longnecker(2016). ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells . Journal of Virology. 90. (8). p. 3860--3872. American Society for Microbiology

Binod Kumar, Roopali Rajput, Gaurav Sharma, Varsha Rawat, Anju Gautam, B. Pattnaik, H. K. Pradhan, Madhu Khanna(2015). Diagnostic Potential of Recombinant scFv Antibodies Generated Against Hemagglutinin Protein of Influenza A Virus . Frontiers in Immunology. 6. Frontiers Media {SA}

Binod Kumar, Mairaj Ahmed Ansari, Sujoy Dutta, Mohanan Valiya Veettil, Dipanjan Dutta, Jawed Iqbal, Arunava Roy, Leela Chikoti, Vivek Vikram Singh, Bala Chandran, et al.(2015). Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses . PLOS Pathogens. 11. (7). p. e1005019. Public Library of Science ({PLoS})

Binod Kumar, Madhu Khanna, Latika Saxena, Roopali Rajput, Rajendra Prasad(2015). Gene silencing: a therapeutic approach to combat influenza virus infections . Future Microbiology. 10. (1). p. 131--140. Future Medicine Ltd

Binod Kumar, Madhu Khanna, Sachin Sharma, Roopali Rajput(2014). Protective Immunity Based on the Conserved Hemagglutinin Stalk Domain and Its Prospects for Universal Influenza Vaccine Development . BioMed Research International. 2014. p. 1--7. Hindawi Publishing Corporation

Influenza virus Induced Cytokine Responses: An Evaluation of Host-Pathogen Association @article{2014,doi = {10.4172/1745-7580.s2.001},url = {https://doi.org/10.4172%2F1745-7580.s2.001},year = 2014,publisher = {{OMICS} Publishing Group},volume = {01},number = {s2},title = {Influenza virus Induced Cytokine Responses: An Evaluation of Host-Pathogen Association},journal = {Immunome Research}} . Immunome Research.

Binod Kumar, Prashant Kumar, Roopali Rajput, Latika Saxena, Mradul K. Daga, Madhu Khanna(2013). Sequence-Specific Cleavage of BM2 Gene Transcript of Influenza B Virus by 10-23 Catalytic Motif Containing DNA Enzymes Significantly Inhibits Viral RNA Translation and Replication . Nucleic Acid Therapeutics. 23. (5). p. 355--362. Mary Ann Liebert Inc

Binod Kumar, Prashant Kumar, Roopali Rajput, Latika Saxena, Akhil C. Banerjea, Madhu Khanna(2013). Cross-Protective Effect of Antisense Oligonucleotide Developed Against the Common 3′ NCR of Influenza A Virus Genome . Molecular Biotechnology. 55. (3). p. 203--211. Springer Nature

Binod Kumar, Madhu Khanna, Latika Saxena, Ankit Gupta, Roopali Rajput(2013). Influenza pandemics of 1918 and 2009: a comparative account . Future Virology. 8. (4). p. 335--342. Future Medicine Ltd

(2013). Clinical presentation of patients with seasonal influenza and pandemic influenza A (H1N1-2009) requiring hospitalisation. Indian J Chest Dis Allied Sci.

(2012). Resolution of immune response by recombinant transforming growth factor-beta (rTGF-β) during influenza A virus infection. The Indian Journal of Medical Research.

(2012). Comparative reproducibility of SYBR Green I and TaqMan real-time PCR chemistries for the analysis of matrix and hemagglutinin genes of Influenza A viruses. International Journal of Collaborative Research on Internal Medicine & Public Health.

Binod Kumar, Madhu Khanna, Ankit Gupta, Prashant Kumar(2012). Pandemic Influenza A H1N1 (2009) Virus: Lessons from the Past and Implications for the Future . Indian Journal of Virology. 23. (1). p. 12--17. Springer Nature

Binod Kumar, Prashant Kumar, Madhu Khanna, Roopali Rajput, Akhil C. Banerjea(2012). A conserved matrix epitope based DNA vaccine protects mice against influenza A virus challenge . Antiviral Research. 93. (1). p. 78--85. Elsevier {BV}

Binod Kumar, Madhu Khanna, Prashant Kumar, MradulK Daga, Varinder Singh, S Khare, SN Gaur, DibyaR Pati(2012). Age-sex distribution and seasonality pattern among influenza virus infected patients in Delhi, 2009-2010 . Indian Journal of Community Medicine. 37. (1). p. 57. Medknow

B. Kumar, Madhu Khanna, P. Kumar, V. Sood, R. Vyas, A. C. Banerjea(2011). Nucleic Acid-Mediated Cleavage of M1 Gene of Influenza A Virus Is Significantly Augmented by Antisense Molecules Targeted to Hybridize Close to the Cleavage Site . Molecular Biotechnology. 51. (1). p. 27--36. Springer Nature

B. Kumar, P. Kumar, R. Rajput, M.K. Daga, M. Khanna(2011). OL-055 Evaluation of SYBR Green I and TaqMan real-time PCR chemistries for specific detection of influenza A viruses . International Journal of Infectious Diseases. 15. p. S33. Elsevier {BV}

(2011). Quantification of viral load in clinical specimens collected from different body sites of patients infected with influenza viruses. International Journal of Medicine and Medical Sciences.

(2010). Comparison of various immunoassay kits for rapid screening of pandemic influenza H1N1-2009 viruses. Journal of Public Health and Epidemiology.

B. Kumar, P. Kumar, R. Rajput, M. Khanna(2010). PP-074 Small interfering RNA (siRNA) mediated inhibition of influenza A virus replication in mammalian cell line . International Journal of Infectious Diseases. 14. p. S47. Elsevier {BV}

M. Khanna, A. Ray, S. Rawall, S. Chandna, B. Kumar, V. K. Vijayan(2010). Detection of Influenza Virus Induced Ultrastructural Changes and DNA Damage . Indian Journal of Virology. 21. (1). p. 50--55. Springer Nature

P. Kumar, B. Kumar, A. Gupta, B. Sharma, V. K. Vijayan, S. Khare, V. Singh, M. K. Daga, M. S. Chadha, A. C. Mishra, et al.(2010). Diagnosis of Novel Pandemic Influenza Virus 2009 H1N1 in Hospitalized Patients . Indian Journal of Virology. 21. (1). p. 45--49. Springer Nature

Binod Kumar, Madhu Khanna, Neha Gupta, Prashant Kumar, Ankit Gupta, V. K. Vijayan, Harpreet Kaur(2009). Pandemic swine influenza virus (H1N1): A threatening evolution . Indian Journal of Microbiology. 49. (4). p. 365--369. Springer Nature

M. Khanna, P. Kumar, K. Choudhary, B. Kumar, V. K. Vijayan(2008). Emerging influenza virus: A global threat . Journal of Biosciences. 33. (4). p. 475--482. Springer Nature

BOOK CHAPTER

(2019). Proximity Ligation Assay (PLA) to Determine the Endosomal Localization of ESCRT Subunit in Virus-Infected Cells . Methods in Molecular Biology.

(2018). Hepatitis C Virus and Inflammation. Hepatitis C From Infection to Cure.

(2018). Preventing Zoonotic Influenza. Influenza-Therapeutics and Challenges.