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Profile Details
Subject Matter Expertise
Services
Work Experience
Principal Investigator
Riga Stradiņš University
December 2019 - Present
CEO
net-OMICS
August 2017 - Present
Postdoctoral Research Fellow
The German Heart Centre Munich, Department of Cardiovascular Diseases in Adults, Technical University Munich
August 2013 - Present
Senior Scientist
Institute of Food Safety, Animal Health and Environment “BIOR”
September 2018 - November 2019
Postdoctoral Research Fellow
The German Heart Centre Munich, Technical University Munich
August 2013 - August 2018
Education
PhD
Technical University Munich, Laboratory of Stem Cell Physiology, 3rd Department of Internal Medicine, Klinikum rechts der Isar | Institute for Bioinformatics and Systems Biology, Helmholtz Zentrum Munich
March 2009 - August 2013
PhD (3rd Department of Internal Medicine, Laboratory of Stem Cell Physiology)
Klinikum rechts der Isar der Technischen Universität München
March 2009 - July 2013
PhD
Helmholtz Zentrum München Institute of Bioinformatics and Systems Biology
March 2009 - July 2013
MSc ( Department of Genome Oriented Bioinformatics)
Technical University Munich
October 2006 - March 2009
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
(2019). Machine Learning Approaches for Epidemiological Investigations of Food-Borne Disease Outbreaks . Frontiers in microbiology.
(2018). Genetics of coronary artery disease in the light of genome-wide association studies . Clinical research in cardiology : official journal of the German Cardiac Society.
(2018). Integrating Genes Affecting Coronary Artery Disease in Functional Networks by Multi-OMICs Approach . Frontiers in cardiovascular medicine.
Lempiäinen, H., Brænne, I., Michoel, T., Tragante, V., Vilne, B., Webb, T.R., Kyriakou, T., Eichner, J., Zeng, L., Willenborg, C., et al.(2018). Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets . Scientific Reports. 8. (1).
Schunkert, H., von Scheidt, M., Kessler, T., Stiller, B., Zeng, L., Vilne, B.(2018). Genetics of coronary artery disease in the light of genome-wide association studies . Clinical Research in Cardiology. 107. p. 2-9.
Kessler, T., Wobst, J., Wolf, B., Eckhold, J., Vilne, B., Hollstein, R., Von Ameln, S., Dang, T.A., Sager, H.B., Rumpf, P.M., et al.(2017). Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus . Circulation. 136. (5). p. 476-489.
Vilne, B., Skogsberg, J., Foroughi Asl, H., Talukdar, H.A., Kessler, T., Björkegren, J.L.M., Schunkert, H.(2017). Network analysis reveals a causal role of mitochondrial gene activity in atherosclerotic lesion formation . Atherosclerosis. 267. p. 39-48.
Kessler, T., Vilne, B., Schunkert, H.(2016). The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease . EMBO Molecular Medicine. 8. (7). p. 688-701.
Kessler, T., Erdmann, J., Vilne, B., Bruse, P., Kurowski, V., Diemert, P., Schunkert, H., Sager, H.B.(2016). Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism . Journal of Translational Medicine. 14. (1).
Franke, K., Vilne, B., da Costa, O.P., Rudelius, M., Peschel, C., Oostendorp, R.A.J., Keller, U.(2015). In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment . Oncotarget. 6. (26). p. 21827-21839.
Brnne, I., Civelek, M., Vilne, B., Di Narzo, A., Johnson, A.D., Zhao, Y., Reiz, B., Codoni, V., Webb, T.R., Asl, H.F., et al.(2015). Prediction of causal candidate genes in coronary artery disease loci . Arteriosclerosis, Thrombosis, and Vascular Biology. 35. (10). p. 2207-2217.
Istvánffy, R., Vilne, B., Schreck, C., Ruf, F., Pagel, C., Grziwok, S., Henkel, L., Prazeres Da Costa, O., Berndt, J., Stümpflen, V., et al.(2015). Stroma-derived connective tissue growth factor maintains cell cycle progression and repopulation activity of hematopoietic stem cells in vitro . Stem Cell Reports. 5. (5). p. 702-715.
Luo, Q., Pagel, P., Vilne, B., Frishman, D.(2011). DIMA 3.0: Domain interaction map . Nucleic Acids Research. 39. (SUPPL. 1).
Istvanffy, R., Kröger, M., Eckl, C., Gitzelmann, S., Vilne, B., Bock, F., Graf, S., Schiemann, M., Keller, U.B., Peschel, C., et al.(2011). Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells . Blood. 118. (10). p. 2712-2722.