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Profile Details
Subject Matter Expertise
Services
Writing
Medical Writing,
Newswriting,
General Proofreading & Editing
Research
Meta-Research,
Systematic Literature Review
Consulting
Healthcare Consulting,
Scientific and Technical Consulting
Work Experience
Postdoctoral Reseach Fellow
UTHealth Houston
March 2020 - January 2025
Postdoctoral Research fellow
Deakin University (Melbourne, Australia)
September 2014 - March 2018
Education
PhD | Neuroscience
Federal University of Rio Grande do Sul
January 2010 - May 2014
Masters of Science
Federal University of Rio Grande do Sul
January 2008 - December 2009
Medical Degree (MD)
Federal University of Health Sciences of Porto Alegre
January 1998 - December 2002
Certifications
Publications
JOURNAL ARTICLE
Nitesh Enduru, Brisa S. Fernandes, Shahram Bahrami, Yulin Dai, Ole A. Andreassen, Zhongming Zhao (2024). Genetic overlap between Alzheimer’s disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence . Molecular Psychiatry.
Brisa S. Fernandes, Zhongming Zhao (2023). Improving drug development in precision psychiatry by ameliorating cognitive biases . European Neuropsychopharmacology.
Brisa S. Fernandes, Mehmet Enes Inam, Nitesh Enduru, Joao Quevedo, Zhongming Zhao (2023). The kynurenine pathway in Alzheimer's disease: a meta-analysis of central and peripheral levels . Brazilian Journal of Psychiatry.
Mehmet Enes Inam, Brisa S. Fernandes, Estela Salagre, Iria Grande, Eduard Vieta, João Quevedo, Zhongming Zhao (2023). The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a systematic review and meta-analysis of cerebrospinal fluid studies . Brazilian Journal of Psychiatry.
Brisa S. Fernandes, João Quevedo, Zhongming Zhao(2022). Fostering precision psychiatry through bioinformatics . Brazilian Journal of Psychiatry. {FapUNIFESP} ({SciELO})
Alexandre P. Diaz, Brisa S. Fernandes, Joao Quevedo, Marsal Sanches, Jair C. Soares(2022). Treatment-resistant bipolar depression: concepts and challenges for novel interventions . Brazilian Journal of Psychiatry. {FapUNIFESP} ({SciELO})
Fernandes, Brisa (2021). Fostering transformational research in academia through leadership: Lessons from business . Bipolar Disorders.
Fernandes, Brisa, Diaz, Alexandre Paim, Scaini, Giselli, Mwangi, Benson, Wu, Mon-Ju, Quevedo, Joao, Sanches, Marsal, Soares, Jair (2021). C-Reactive Protein and the Uncinate Fasciculus in Anhedonia and Depression . Biological Psychiatry.
Diaz, Alexandre Paim, Fernandes, Brisa, Zeni, Cristian, Saxena, Kirti, Sanches, Marsal, Soares, Jair (2021). Lower Reward Responsiveness is Associated With Lifetime Suicide Attempt in Children and Adolescents With Bipolar Disorders . Biological Psychiatry.
Diaz, Alexandre Paim, Cuellar, Valeria A., Vinson, Elizabeth L., Suchting, Robert, Durkin, Kathryn, Fernandes, Brisa S., Scaini, Giselli, Kazimi, Iram, Zunta-Soares, Giovana B., Quevedo, Joao, et al. (2021). The Greater Houston Area Bipolar Registry-Clinical and Neurobiological Trajectories of Children and Adolescents With Bipolar Disorders and High-Risk Unaffected Offspring . Frontiers in Psychiatry.
Marx, Wolfgang, McGuinness, Amelia J., Rocks, Tetyana, Ruusunen, Anu, Cleminson, Jasmine, Walker, Adam J., Gomes-da-Costa, Susana, Lane, Melissa, Sanches, Marsal, Diaz, Alexandre P., et al. (2021). The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies . Molecular Psychiatry.
Fernandes, Brisa, Marx, Wolfgang, McGuinness, Amelia, Diaz, Alexandre, Sanches, Marsal, Quevedo, Joao, Soares, Jair (2021). The Kynurenine Pathway in Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: A Large Meta-Analysis . Biological Psychiatry.
Fernandes, Brisa S., Borgwardt, Stefan, Carvalho, Andre F., Steiner, Johann (2020). Editorial: Back to the Future: On the Road Towards Precision Psychiatry . Frontiers in Psychiatry.
Ottesen, Ninja Meinhard, Meluken, Iselin, Frikke-Schmidt, Ruth, Plomgaard, Peter, Scheike, Thomas, Fernandes, Brisa S., Berk, Michael, Poulsen, Henrik Enghusen, Kessing, Lars Vedel, Miskowiak, Kamilla, et al. (2020). Are remitted affective disorders and familial risk of affective disorders associated with metabolic syndrome, inflammation and oxidative stress? - a monozygotic twin study . Psychological Medicine.
Carvalho, Andre F., Solmi, Marco, Sanches, Marcos, Machado, Myrela O., Stubbs, Brendon, Ajnakina, Olesya, Sherman, Chelsea, Sun, Yue Ran, Liu, Celina S., Brunoni, Andre R., et al. (2020). Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders . Translational Psychiatry.
Steiner, Johann, Frodl, Thomas, Schiltz, Kolja, Dobrowolny, Henrik, Jacobs, Roland, Fernandes, Brisa S., Guest, Paul C., Meyer-Lotz, Gabriela, Borucki, Katrin, Bahn, Sabine, et al. (2020). Innate Immune Cells and C-Reactive Protein in Acute First-Episode Psychosis and Schizophrenia: Relationship to Psychopathology and Treatment . Schizophrenia Bulletin.
Fernandes, Brisa, Marx, Wolfgang, McGuinness, Amelia, Diaz, Alexandre Paim, Soares, Jair (2020). The Kynurenine Pathway in Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: A Meta-Analysis of 101 Studies . Neuropsychopharmacology.
Fernandes, Brisa S., Karmakar, Chandan, Tamouza, Ryad, Tran, Truyen, Yearwood, John, Hamdani, Nora, Laouamri, Hakim, Richard, Jean-Romain, Yolken, Robert, Berk, Michael, et al. (2020). Precision psychiatry with immunological and cognitive biomarkers: a multi-domain prediction for the diagnosis of bipolar disorder or schizophrenia using machine learning . Translational Psychiatry.
Fernandes, B., Scotti-Muzzi, E., Soeiro-de-Souza, M. (2020). Antidepressant treatment decreases IL-6, IL-10 and serum cortisol in major depressive disorder: a meta-analysis of randomized controlled trials . European Neuropsychopharmacology.
Kallen, Victor, Fernandes, Brisa (2019). Applying biomarkers in psychiatry: Paving the way towards precision psychiatry . Psychoneuroendocrinology.
Andreazza, Ana C., Laksono, Isabelle, Fernandes, Brisa S., Toben, Catherine, Lewczuk, Piotr, Riederer, Peter, Kennedy, Sidney H., Kapogiannis, Dimitrios, Thibaut, Florence, Gerlach, Manfred, et al. (2019). Guidelines for the standardized collection of blood-based biomarkers in psychiatry: Steps for laboratory validity - a consensus of the Biomarkers Task Force from the WFSBP . The World Journal of Biological Psychiatry.
Ottesen, N. M., Ottesen, N. M., Meluken, I., Meluken, I., Frikke-Schmidt, R., Frikke-Schmidt, R., Plomgaard, P., Plomgaard, P., Henrik, E. P., Henrik, E. P., et al. (2019). Metabolic syndrome, inflammation and oxidative stress as potential risk factors for affective disorders - a twin study . European Neuropsychopharmacology.
Fernandes, Brisa, Karmakar, Chandan, Berk, Michael, Leboyer, Marion (2019). Precision Psychiatry With Immunological and Cognitive Biomarkers: A Multi-Domain Prediction for the Diagnosis of Bipolar Disorder or Schizophrenia Using Machine Learning . Neuropsychopharmacology.
Carvalho, Andre F., Fernandes, Brisa S., Brunoni, Andre R. (2019). Mindfulness-based stress reduction for fibromyalgia: A step closer to precision psychiatry? . Brain, Behavior, and Immunity.
Cristiano A. Köhler, Evangelos Evangelou, Brendon Stubbs, Marco Solmi, Nicola Veronese, Lazaros Belbasis, Beatrice Bortolato, Matias C.A. Melo, Camila A. Coelho, Brisa S. Fernandes, et al.(2018). Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies . Journal of Psychiatric Research. 103. p. 189--207. Elsevier {BV}
Bortolato, B., Hyphantis, T.N., Valpione, S., Perini, G., Maes, M., Morris, G., Kubera, M., Köhler, C.A., Fernandes, B.S., Stubbs, B., et al.(2017). Depression in cancer: The many biobehavioral pathways driving tumor progression . Cancer Treatment Reviews. 52. p. 58-70.
Soysal, P., Isik, A.T., Carvalho, A.F., Fernandes, B.S., Solmi, M., Schofield, P., Veronese, N., Stubbs, B.(2017). Oxidative stress and frailty: A systematic review and synthesis of the best evidence . Maturitas. 99. p. 66-72.
Salagre, E., Vizuete, A.F., Leite, M., Brownstein, D.J., McGuinness, A., Jacka, F., Dodd, S., Stubbs, B., Köhler, C.A., Vieta, E., et al.(2017). Homocysteine as a peripheral biomarker in bipolar disorder: A meta-analysis . European Psychiatry. 43. p. 81-91.
Köhler, C.A., Freitas, T.H., Stubbs, B., Maes, M., Solmi, M., Veronese, N., de Andrade, N.Q., Morris, G., Fernandes, B.S., Brunoni, A.R., et al.(2017). Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis . Molecular Neurobiology. p. 1-12.
Köhler, C.A., Freitas, T.H., Maes, M., de Andrade, N.Q., Liu, C.S., Fernandes, B.S., Stubbs, B., Solmi, M., Veronese, N., Herrmann, N., et al.(2017). Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies . Acta Psychiatrica Scandinavica. 135. (5). p. 373-387.
Soysal, P., Veronese, N., Thompson, T., Kahl, K.G., Fernandes, B.S., Prina, A.M., Solmi, M., Schofield, P., Koyanagi, A., Tseng, P.-T., et al.(2017). Relationship between depression and frailty in older adults: A systematic review and meta-analysis . Ageing Research Reviews. 36. p. 78-87.
Fernandes, B.S., Berk, M.(2017). Staging in bipolar disorder: One step closer to precision psychiatry . Revista Brasileira de Psiquiatria. 39. (2). p. 88-89.
Chavarria, V., Vian, J., Pereira, C., Data-Franco, J., Fernandes, B.S., Berk, M., Dodd, S.(2017). The Placebo and Nocebo Phenomena: Their Clinical Management and Impact on Treatment Outcomes . Clinical Therapeutics. 39. (3). p. 477-486.
Skvarc, D.R., Dean, O.M., Byrne, L.K., Gray, L., Lane, S., Lewis, M., Fernandes, B.S., Berk, M., Marriott, A.(2017). The effect of N-acetylcysteine (NAC) on human cognition – A systematic review . Neuroscience and Biobehavioral Reviews. 78. p. 44-56.
Vian, J., Pereira, C., Chavarria, V., Köhler, C., Stubbs, B., Quevedo, J., Kim, S.-W., Carvalho, A.F., Berk, M., Fernandes, B.S.(2017). The renin-angiotensin system: A possible new target for depression . BMC Medicine. 15. (1).
Salagre, E., Solé, B., Tomioka, Y., Fernandes, B.S., Hidalgo-Mazzei, D., Garriga, M., Jimenez, E., Sanchez-Moreno, J., Vieta, E., Grande, I.(2017). Treatment of neurocognitive symptoms in unipolar depression: A systematic review and future perspectives . Journal of Affective Disorders. 221. p. 205-221.
Fernandes, B.S., Williams, L.M., Steiner, J., Leboyer, M., Carvalho, A.F., Berk, M.(2017). The new field of 'precision psychiatry' . BMC Medicine. 15. (1).
B.S. Fernandes, S. Dash, F. Jacka, S. Dodd, A.F. Carvalho, C.A. Köhler, J. Steiner, M. da Graça Cantarelli, P. Nardin, C.-A. Gonçalves, et al.(2016). Leptin in bipolar disorder: A systematic review and meta-analysis . European Psychiatry. 35. p. 1--7. Elsevier {BV}
Fernandes, B.S., Dash, S., Jacka, F., Dodd, S., Carvalho, A.F., Köhler, C.A., Steiner, J., da Graça Cantarelli, M., Nardin, P., Gonçalves, C.-A., et al.(2016). Leptin in bipolar disorder: A systematic review and meta-analysis . European Psychiatry. 35. p. 1-7.
Câmara, R.A., Köhler, C.A., Maes, M., Nunes-Neto, P.R., Brunoni, A.R., Quevedo, J., Fernandes, B.S., Perugi, G., Hyphantis, T.N., Carvalho, A.F.(2016). Affective temperaments and emotional traits are associated with a positive screening for premenstrual dysphoric disorder . Comprehensive Psychiatry. 71. p. 33-38.
Williams, L.J., Pasco, J.A., Kessing, L.V., Quirk, S.E., Fernandes, B.S., Berk, M.(2016). Angiotensin converting enzyme inhibitors and risk of mood disorders . Psychotherapy and Psychosomatics. 85. (4). p. 250-252.
Carvalho, A.F., Köhler, C.A., Brunoni, A.R., Miskowiak, K.W., Herrmann, N., Lanctôt, K.L., Hyphantis, T.N., Quevedo, J., Fernandes, B.S., Berk, M.(2016). Bias in Peripheral Depression Biomarkers . Psychotherapy and Psychosomatics. 85. (2). p. 81-90.
Fernandes, B.S., Steiner, J., Molendijk, M.L., Dodd, S., Nardin, P., Gonçalves, C.-A., Jacka, F., Köhler, C.A., Karmakar, C., Carvalho, A.F., et al.(2016). C-reactive protein concentrations across the mood spectrum in bipolar disorder: a systematic review and meta-analysis . The Lancet Psychiatry. 3. (12). p. 1147-1156.
Fernandes, B.S., Steiner, J., Bernstein, H.-G., Dodd, S., Pasco, J.A., Dean, O.M., Nardin, P., Gonçalves, C.-A., Berk, M.(2016). C-reactive protein is increased in schizophrenia but is not altered by antipsychotics: Meta-analysis and implications . Molecular Psychiatry. 21. (4). p. 554-564.
Bortolato, B., Miskowiak, K.W., Köhler, C.A., Maes, M., Fernandes, B.S., Berk, M., Carvalho, A.F.(2016). Cognitive remission: A novel objective for the treatment of major depression? . BMC Medicine. 14. (1).
Carvalho, A.F., Köhler, C.A., Fernandes, B.S., Quevedo, J., Miskowiak, K.W., Brunoni, A.R., Machado-Vieira, R., Maes, M., Vieta, E., Berk, M.(2016). Bias in emerging biomarkers for bipolar disorder . Psychological Medicine. 46. (11). p. 2287-2297.
Salagre, E., Fernandes, B.S., Dodd, S., Brownstein, D.J., Berk, M.(2016). Statins for the treatment of depression: A meta-analysis of randomized, double-blind, placebo-controlled trials . Journal of Affective Disorders. 200. p. 235-242.
Fernandes, B.S., Hodge, J.M., Pasco, J.A., Berk, M., Williams, L.J.(2016). Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression . Drugs and Aging. 33. (1). p. 21-25.
Fernandes, B.S., Dean, O.M., Dodd, S., Malhi, G.S., Berk, M.(2016). N-acetylcysteine in depressive symptoms and functionality: A systematic review and meta-analysis . Journal of Clinical Psychiatry. 77. (4). p. e457-e466.
Slyepchenko, A., Maes, M., Köhler, C.A., Anderson, G., Quevedo, J., Alves, G.S., Berk, M., Fernandes, B.S., Carvalho, A.F.(2016). T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model . Neuroscience and Biobehavioral Reviews. 64. p. 83-100.
Dodd, S., Fernandes, B.S., Dean, O.M.(2015). Future directions for pharmacotherapies for treatment-resistant bipolar disorder . Current Neuropharmacology. 13. (5). p. 656-662.
Fernandes, B.S., Steiner, J., Berk, M., Molendijk, M.L., Gonzalez-Pinto, A., Turck, C.W., Nardin, P., Gonçalves, C.-A.(2015). Peripheral brain-derived neurotrophic factor in schizophrenia and the role of antipsychotics: Meta-analysis and implications . Molecular Psychiatry. 20. (9). p. 1108-1119.
Carvalho, A.F., Köhler, C.A., McIntyre, R.S., Knöchel, C., Brunoni, A.R., Thase, M.E., Quevedo, J., Fernandes, B.S., Berk, M.(2015). Peripheral vascular endothelial growth factor as a novel depression biomarker: A meta-analysis . Psychoneuroendocrinology. 62. p. 18-26.
Fernandes, B.S., Molendijk, M.L., Köhler, C.A., Soares, J.C., Leite, C.M.G.S., Machado-Vieira, R., Ribeiro, T.L., Silva, J.C., Sales, P.M.G., Quevedo, J., et al.(2015). Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: A meta-analysis of 52 studies . BMC Medicine. 13. (1).
Da Graça Cantarelli, M., Nardin, P., Buffon, A., Eidt, M.C., Antônio Godoy, L., Fernandes, B.S., Gonçalves, C.-A.(2015). Serum triglycerides, but not cholesterol or leptin, are decreased in suicide attempters with mood disorders . Journal of Affective Disorders. 172. p. 403-409.
Fernandes, B. S., Berk, M., Turck, C. W., Steiner, J., Goncalves, C. A.(2014). Decreased peripheral brain-derived neurotrophic factor levels are a biomarker of disease activity in major psychiatric disorders: a comparative meta-analysis . Molecular Psychiatry. 19. (7). p. 749-751.
Fernandes, B.S., Berk, M., Turck, C.W., Steiner, J., Gonçalves, C.-A.(2014). Decreased peripheral brain-derived neurotrophic factor levels are a biomarker of disease activity in major psychiatric disorders: A comparative meta-analysis . Molecular Psychiatry. 19. (7). p. 749-751.
Frey, Benicio N., Andreazza, Ana C., Houenou, Josselin, Jamain, Stephane, Goldstein, Benjamin I., Frye, Mark A., Leboyer, Marion, Berk, Michael, Malhi, Gin S., Lopez-Jaramillo, Carlos, et al.(2013). Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force . Australian and New Zealand Journal of Psychiatry. 47. (4). p. 321-332.
Frey, B.N., Andreazza, A.C., Houenou, J., Jamain, S., Goldstein, B.I., Frye, M.A., Leboyer, M., Berk, M., Malhi, G.S., Lopez-Jaramillo, C., et al.(2013). Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force . Australian and New Zealand Journal of Psychiatry. 47. (4). p. 321-332.
Fernandes, B. S., Berk, M., Goncalves, C.(2013). Decreased peripheral brain-derived neurotrophic factor levels are not specific for bipolar disorder, major depressive disorder or schizophrenia: a meta-analysis. Bipolar Disorders. 15. p. 40.
Santos, K., Palmini, A., Radziuk, A.L., Rotert, R., Bastos, F., Booij, L., Fernandes, B.S.(2013). The impact of methylphenidate on seizure frequency and severity in children with attention-deficit-hyperactivity disorder and difficult-to-treat epilepsies . Developmental Medicine and Child Neurology. 55. (7). p. 654-660.
Santos, Kleber, Palmini, Andre, Radziuk, Ana L., Rotert, Rosana, Bastos, Fernanda, Booij, Linda, Fernandes, Brisa S.(2013). The impact of methylphenidate on seizure frequency and severity in children with attention-deficit-hyperactivity disorder and difficult-to-treat epilepsies . Developmental Medicine and Child Neurology. 55. (7). p. 654-660.
Berk, M., Dean, O.M., Cotton, S.M., Gama, C.S., Kapczinski, F., Fernandes, B., Kohlmann, K., Jeavons, S., Hewitt, K., Moss, K., et al.(2012). Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial . BMC Medicine. 10.
Salvador, Jaqueline, Massuda, Raffael, Andreazza, Tahiana, Koff, Walter Jose, Silveira, Esalba, Kreische, Fernanda, de Souza, Livia, de Oliveira, Maria Helena, Rosito, Tiago, Fernandes, Brisa S., et al.(2012). Minimum 2-year follow up of sex reassignment surgery in Brazilian male-to-female transsexuals . Psychiatry and Clinical Neurosciences. 66. (4). p. 371-372.
Zortea, Karine, Fernandes, Brisa Simoes, Guimaraes, Lisia Rejane, Francesconi, Lenise Petter, Lersch, Camila, Gama, Clarissa Severino, Schroeder, Rafael, Zanotto-Filho, Alfeu, Moreira, Jose Claudio, Rodrigues Lobato, Maria Ines, et al.(2012). Reduced serum non-enzymatic antioxidant defense and increased lipid peroxidation in schizophrenic patients on a hypocaloric diet . Neuroscience Letters. 512. (1). p. 43-47.
Salvador, J., Massuda, R., Andreazza, T., Koff, W.J., Silveira, E., Kreische, F., De Souza, L., De Oliveira, M.H., Rosito, T., Fernandes, B.S., et al.(2012). Minimum 2-year follow up of sex reassignment surgery in Brazilian male-to-female transsexuals . Psychiatry and Clinical Neurosciences. 66. (4). p. 371-372.
Berk, Michael, Dean, Olivia M., Cotton, Sue M., Gama, Clarissa S., Kapczinski, Flavio, Fernandes, Brisa, Kohlmann, Kristy, Jeavons, Susan, Hewitt, Karen, Moss, Kirsteen, et al.(2012). Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial . Bmc Medicine. 10.
Zortea, K., Fernandes, B.S., Guimarães, L.R., Francesconi, L.P., Lersch, C., Gama, C.S., Schroeder, R., Zanotto-Filho, A., Moreira, J.C., Lobato, M.I.R., et al.(2012). Reduced serum non-enzymatic antioxidant defense and increased lipid peroxidation in schizophrenic patients on a hypocaloric diet . Neuroscience Letters. 512. (1). p. 43-47.
de Lucena, David, Fernandes, B. S., Berk, M., Dodd, S., Medeiros, D. W., Pedrini, M., Kunz, M., Gomes, F. A., Giglio, L. F., Lobato, M., I, et al.(2011). Improvement of Negative and Positive Symptoms in Treatment-Refractory Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled Trial With Memantine as Add-On Therapy to Clozapine (vol 70, pg 1416, 2009). Journal of Clinical Psychiatry. 72. (8). p. 1157.
Kunz, M., Ceresér, K.M., Goi, P.D., Fries, G.R., Teixeira, A.L., Fernandes, B.S., Belmonte-de-Abreu, P.S., Kauer-Sant'Anna, M., Kapczinski, F., Gama, C.S.(2011). Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: Differences in pro- and anti-inflammatory balance | Níveis séricos de IL-6, IL-10 e TNF-α em pacientes com transtorno bipolar e esquizofrenia: Diferenças no equilíbrio pró e antiinflamatório . Revista Brasileira de Psiquiatria. 33. (3). p. 268-274.
Kunz, Mauricio, Ceresér, Keila Maria, Goi, Pedro Domingues, Fries, Gabriel Rodrigo, Teixeira, Antonio L., Fernandes, Brisa Simões, Belmonte-de-Abreu, Paulo Silva, Kauer-Sant'Anna, Márcia, Kapczinski, Flavio, Gama, Clarissa Severino(2011). Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance . Revista Brasileira de Psiquiatria. (ahead). p. 0.
Kunz, Mauricio, Cereser, Keila Maria, Goi, Pedro Domingues, Fries, Gabriel Rodrigo, Teixeira, Antonio L., Fernandes, Brisa Simoes, Belmonte-de-Abreu, Paulo Silva, Kauer-Sant'Anna, Marcia, Kapczinski, Flavio, Gama, Clarissa Severino(2011). Serum levels of IL-6, IL-10 and TNF-alpha in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance. Revista Brasileira De Psiquiatria. 33. (3). p. 268-274.
Berk, Michael, Dean, Olivia, Cotton, Sue M., Gama, Clarissa S., Kapczinski, Flavio, Fernandes, Brisa S., Kohlmann, Kristy, Jeavons, Susan, Hewitt, Karen, Allwang, Christine, et al.(2011). The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: An open label trial . Journal of Affective Disorders. 135. (1-3). p. 389-394.
Berk, M., Dean, O., Cotton, S.M., Gama, C.S., Kapczinski, F., Fernandes, B.S., Kohlmann, K., Jeavons, S., Hewitt, K., Allwang, C., et al.(2011). The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: An open label trial . Journal of Affective Disorders. 135. (1-3). p. 389-394.
Kieling, C., Gama, C.S., Fernandes, B.S.(2011). Hypersalivation associated with olanzapine and valproate combination: A case report . CNS Spectrums. 16. (3).
Fernandes, Brisa Simoes, Gama, Clarissa Severino, Cereser, Keila Maria, Yatham, Lakshmi N., Fries, Gabriel Rodrigo, Colpo, Gabriela, de Lucena, David, Kunz, Mauricio, Gomes, Fabiano Alves, Kapczinski, Flavio(2011). Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis . Journal of Psychiatric Research. 45. (8). p. 995-1004.
Fernandes, B.S., Gama, C.S., Maria Ceresér, K., Yatham, L.N., Fries, G.R., Colpo, G., de Lucena, D., Kunz, M., Gomes, F.A., Kapczinski, F.(2011). Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis . Journal of Psychiatric Research. 45. (8). p. 995-1004.
Fernandes, Brisa S., Goncalves, Carlos Alberto S.(2011). Decreased Peripheral Brain-derived Neurotrophic Factor Levels are Not Specific for Schizophrenia or Mood Disorders. Biological Psychiatry. 69. (9). p. 65S.
Fernandes, B. S., Goncalves, C. A. S.(2011). Decreased peripheral brain-derived neurotrophic factor levels are not specific for bipolar disorder, major depressive disorder or schizophrenia. Bipolar Disorders. 13. p. 44-45.
Kieling, Christian, Gama, Clarissa Severino, Fernandes, Brisa Simoes(2011). HYPERSALIVATION ASSOCIATED WITH OLANZAPINE AND VALPROATE COMBINATION: A CASE REPORT . Cns Spectrums. 16. (3). p. 83.
Cereser, Keila M. M., Fernandes, Brisa S., Fries, Gabriel, Colpo, Gabriela, Pasquali, Matheus, Schnorr, Carlos Eduardo, Gama, Clarissa S., Moreira, Jose Claudio(2010). Biomarkers of Oxidative Stress in Chronic Stabilized Patients with Schizophrenia and Euthymic Patients with Bipolar Disorder. Biological Psychiatry. 67. (9). p. 167S.
Narvaez, J. M., Fernandes, B. S., Vieira, D. C., Tramontina, J. F., Trindade, E. K., Kapczinski, N. S., Kauer-Sant'Anna, M., Kapczinski, F. P.(2010). Cognitive assessment in a crack users population with and without mood disorders: a pilot study. Bipolar Disorders. 12. p. 40-41.
Fernandes, B. S., Gomes, F. A., Fries, G., Stertz, L., Cereser, K. M., Pessoa, C., Gama, C. S., Kapczinski, F.(2010). Brain-derived neurotrophic factor as a possible biomarker of bipolar disorder activity. Bipolar Disorders. 12. p. 19.
Fernandes, B. S., Cereser, K. M., Zortea, K., Fries, G. R., Colpo, G., Moreira, L., Kapczinski, F., Gama, C. S.(2010). Complement system in bipolar disorders and schizophrenia: C3 and C4. Bipolar Disorders. 12. p. 18-19.
Gomes, F. A., Fernandes, B. S., Gama, C. S., Magalhaes, P. V., Walz, J. C., Kapczinski, F.(2010). Correlation between serum brain-derived neurotrophic factor and neurotrophin-3 levels in bipolar disorder. Bipolar Disorders. 12. p. 22.
Fries, G. R., Lersch, C., de Lima, M. N. M., Stertz, L., Fernandes, B., Kapczinski, F., Saraiva-Pereira, M. L., Schroeder, N.(2010). Early life stress does not alter global DNA methylation in the striatum of an animal model of mania. Bipolar Disorders. 12. p. 20-21.
Fernandes, B. S., Gama, C. S., Cereser, K. M., Gomes, F. A., Kunz, M., Colpo, G. D., Fries, G. R., Kapczinski, F.(2010). Brain-derived neutrotrophic in mania, depression, and euthymia in bipolar disorders: a systematic review and meta-analysis. Bipolar Disorders. 12. p. 19.
Fernandes, Brisa Simoes, Massuda, Raffael, Torres, Mariana, Camargo, Daniel, Fries, Gabriel Rodrigo, Gama, Clarissa Severino, Belmonte-de-Abreu, Paulo Silva, Kapczinski, Flavio, Lobato, Maria Ines(2010). Improvement of schizophrenia with electroconvulsive therapy and serum brain-derived neurotrophic factor levels: Lack of association in a pilot study . Psychiatry and Clinical Neurosciences. 64. (6). p. 663-665.
Fernandes, B.S., Massuda, R., Torres, M., Camargo, D., Fries, G.R., Gama, C.S., Belmonte-De-Abreu, P.S., Kapczinski, F., Lobato, M.I.(2010). Improvement of schizophrenia with electroconvulsive therapy and serum brain-derived neurotrophic factor levels: Lack of association in a pilot study . Psychiatry and Clinical Neurosciences. 64. (6). p. 663-665.
Berk, M., Dean, O., Hewitt, K., Bush, A., Kapczinski, F., Jeavons, S., Gama, C., Malhi, G., Copolov, D., Cobb, H., et al.(2010). Glutathione and redox biology in Bipolar Disorder; from pathophysiology to novel treatments. International Journal of Neuropsychopharmacology. 13. p. 11.
Brietzke, E., Stertz, L., Fernandes, B. S., Kauer-Sant'Anna, M., Mascarenhas, M., Vargas, A. E., Chies, J. A., Kapczinski, F.(2010). Comparison of cytokine levels in depressed, manic, and euthymic patients with bipolar disorder. Bipolar Disorders. 12. p. 10-11.
Fernandes, Brisa Simoes, Gama, Clarissa Severino, Walz, Julio C., Cereser, Keila Maria, Fries, Gabriel Rodrigo, Colpo, Gabriela, Aguiar, Bianca, Pfaffenseller, Bianca, Kauer-Sant'Anna, Marcia, Kapczinski, Flavio(2010). Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes . Journal of Psychiatric Research. 44. (9). p. 561-565.
Fernandes, B.S., Gama, C.S., Walz, J.C., Ceresér, K.M., Fries, G.R., Colpo, G., Aguiar, B., Pfaffenseller, B., Kauer-Sant'Anna, M., Kapczinski, F.(2010). Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes . Journal of Psychiatric Research. 44. (9). p. 561-565.
de Lucena, David, Fernandes, Brisa Simoes, Kunz, Mauricio, Fries, Gabriel Rodrigo, Stertz, Laura, Aguiar, Bianca, Pfaffenseller, Bianca, Gama, Clarissa Severino(2010). Lack of Association Between Serum Brain-Derived Neurotrophic Factor Levels and Improvement of Schizophrenia Symptoms in a Double-Blind, Randomized, Placebo-Controlled Trial of Memantine as Adjunctive Therapy to Clozapine . Journal of Clinical Psychiatry. 71. (1). p. 91-92.
De Lucena, D., Fernandes, B.S., Kunz, M., Fries, G.R., Stertz, L., Aguiar, B., Pfaffenseller, B., Gama, C.S.(2010). Lack of association between serum brain-derived neurotrophic factor levels and improvement of schizophrenia symptoms in a double-blind, randomized, placebo-controlled trial of memantine as adjunctive therapy to clozapine to the editor . Journal of Clinical Psychiatry. 71. (1). p. 91-92.
Fernandes, B. S., Gama, C. S., Walz, J. C., Cereser, K. M., Fries, G. R., Colpo, G. D., Kauer-Sant'Anna, M., Kapczinski, F.(2010). Neurotrophin-3 is increased in patients with bipolar disorder on and off medication during manic and depressive episodes. Bipolar Disorders. 12. p. 19.
Zortea, K., Fernandes, B. S., Lucena, D., Bucker, J., Sulzbach, M., Goi, P., Kapczinski, F., Gama, C. S.(2010). Psychiatric hospitalizations due to bipolar disorder, major depression disorder, and schizophrenia in Rio Grande do Sul, Brazil. Bipolar Disorders. 12. p. 59-60.
Kunz, Mauricio, Cereser, Keila M. M., Fries, Gabriel R., Teixeira, Antonio, Fernandes, Brisa S., Kauer-Sant'Anna, Marcia, Kapczinski, Flavio, Gama, Clarissa S.(2010). Serum Levels of II6, II10 and TNF-Alpha in Patients with Bipolar Disorder in Euthymia and with Schizophrenia: Differences in Pro and Anti-Inflammatory Balance. Biological Psychiatry. 67. (9). p. 132S.
Fernandes, B. S., Pasquali, M. A., Bortolin, R. C., Aguiar, B., Pfaffenseller, B., Moreira, J. C., Kapczinski, F., Gama, C. S.(2010). Serum thiobarbituric acid reactive substances in bipolar disorder during mania and schizophrenia: a biomarker with possible diagnostic implications. Bipolar Disorders. 12. p. 20.
Magalhaes, Pedro V. S., Berk, Michael, Cereser, Keila Maria, Kunz, Mauricio, Gomes, Fabiano Alves, Fernandes, Brisa Simoes, Jakobson, Lourenco, Kapczinski, Flavio, Gama, Clarissa Severino(2010). Validity of the Portuguese version of the Bipolar Depression Rating Scale . Acta Neuropsychiatrica. 22. (2). p. 100-101.
Magalhães, P.V.S., Berk, M., Ceresér, K.M., Kunz, M., Gomes, F.A., Fernandes, B.S., Jakobson, L., Kapczinski, F., Gama, C.S.(2010). Validity of the Portuguese version of the Bipolar Depression Rating Scale . Acta Neuropsychiatrica. 22. (2). p. 100-101.
BRIETZKE, E, STERTZ, L, FERNANDES, BS, KAUER-SANT'ANNA, M, MASCARENHAS, M, VARGAS, AE, CHIES, JA, KAPCZINSKI, F(2009). Comparison of cytokine levels in depressed, manic and euthymic patients with bipolar disorder . JOURNAL OF AFFECTIVE DISORDERS. 116. (3). p. 214-217.
Brietzke, E., Stertz, L., Fernandes, B.S., Kauer-Sant'Anna, M., Mascarenhas, M., Escosteguy Vargas, A., Chies, J.A., Kapczinski, F.(2009). Comparison of cytokine levels in depressed, manic and euthymic patients with bipolar disorder . Journal of Affective Disorders. 116. (3). p. 214-217.
DE OLIVEIRA, GS, CERESER, KM, FERNANDES, BS, KAUER-SANT'ANNA, M, FRIES, GR, STERTZ, L, AGUIAR, B, PFAFFENSELLER, B, KAPCZINSKI, F(2009). Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients . JOURNAL OF PSYCHIATRIC RESEARCH. 43. (14). p. 1171-1174.
de Oliveira, G.S., Ceresér, K.M., Fernandes, B.S., Kauer-Sant'Anna, M., Fries, G.R., Stertz, L., Aguiar, B., Pfaffenseller, B., Kapczinski, F.(2009). Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients . Journal of Psychiatric Research. 43. (14). p. 1171-1174.
De Lucena, D., Fernandes, B.S., Berk, M., Dodd, S., Medeiros, D.W., Pedrini, M., Kunz, M., Gomes, F.A., Giglio, L.F., Lobato, M.I., et al.(2009). Improvement of negative and positive symptoms in treatment-refractory schizophrenia: A double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine . Journal of Clinical Psychiatry. 70. (10). p. 1416-1423.
DE LUCENA, D, FERNANDES, BS, BERK, M, DODD, S, MEDEIROS, DW, PEDRINI, M, KUNZ, M, GOMES, FA, GIGLIO, LF, LOBATO, MI, et al.(2009). Improvement of Negative and Positive Symptoms in Treatment-Refractory Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled Trial With Memantine as Add-On Therapy to Clozapine . JOURNAL OF CLINICAL PSYCHIATRY. 79. (10). p. 1416-1423.
FERNANDES, B, GAMA, CS, MASSUDA, R, et al.(2009). Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): A pilot study in drug resistant depressed patients . NEUROSCIENCE LETTERS. 453. (3). p. 195-198.
Fernandes, B., Gama, C.S., Massuda, R., Torres, M., Camargo, D., Kunz, M., Belmonte-de-Abreu, P.S., Kapczinski, F., de Almeida Fleck, M.P., Inês Lobato, M.(2009). Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): A pilot study in drug resistant depressed patients . Neuroscience Letters. 453. (3). p. 195-198.
FERNANDES, BS, GAMA, CS, KAUER-SANT'ANNA, M, LOBATO, MI, BELMONTE-DE-ABREU, P, KAPCZINSKI, F(2009). Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis . JOURNAL OF PSYCHIATRIC RESEARCH. 43. (15). p. 1200-1204.
Fernandes, B.S., Gama, C.S., Kauer-Sant'Anna, M., Lobato, M.I., Belmonte-de-Abreu, P., Kapczinski, F.(2009). Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis . Journal of Psychiatric Research. 43. (15). p. 1200-1204.
KAPCZINSKI, F, FERNANDES, BS, KAUER-SANT'ANNA, M, GAMA, CS, YATHAM, LN, BERK, M(2009). The concept of staging in bipolar disorder: the role of BDNF and TNF-alpha as biomarkers . ACTA NEUROPSYCHIATRICA. 21. (6). p. 272-274.
Kapczinski, F., Fernandes, B.S., Kauer-Sant'Anna, M., Gama, C.S., Yatham, L.N., Berk, M.(2009). The concept of staging in bipolar disorder: The role of BDNF and TNF-alpha as biomarkers . Acta Neuropsychiatrica. 21. (6). p. 272-274.
Goncalves, D. M., Fernandes, B. S., Kapczinski, F.(2007). Psychological interventions for bipolar disorder reduces the recurrence of new episodes: a systematic review and meta-analysis. Bipolar Disorders. 9. p. 47.
de Pinho, SC, Fernandes, BS, Rodrigues, JAD, Ratusznei, SM, Foresti, E, Zaiat, M (2005). Feasibility of treating swine manure in an anaerobic sequencing batch biofilm reactor with mechanical stirring . Applied Biochemistry and Biotechnology.
Blacher, C., Manfroi, W., Fernandes, B.S.(1999). Evaluation of the treadmill stress testing for risk stratification after acute myocardial infarction . Arquivos Brasileiros de Cardiologia. 73. (6). p. 532-535.
Blacher, C., Manfroi, W., Fernandes, B.S.(1999). Evaluation of the treadmill stress testing for risk stratification after acute myocardial infarction . Arquivos Brasileiros de Cardiologia. 73. (6). p. 527-536.
Leone, C., Freschi, S.A., Yamamoto, T.S., Marques, A.M., Hasegawa, N.M., Primo, E., Fernandes, B.S.(1986). The participating survey in community development | Pesquisa participante no desenvolvimento comunitário . Boletin de la Oficina Sanitaria Panamericana. 101. (5). p. 493-504.
PREPRINT
Andi Liu, Citu Citu, Nitesh Enduru, Xian Chen, Astrid M. Manuel, Tirthankar Sinha, Damian Gorski, Brisa S. Fernandes, Meifang Yu, Paul E. Schulz, et al. (2024). Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease .
Brisa Fernandes, Nitesh Enduru, Shahram Bahrami, Yulin Dai, Ole Andreassen, Zhongming Zhao (2023). Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence .
Xiaoyang Li, Brisa S. Fernandes, Andi Liu, Jingchun Chen, Xiangning Chen, Zhongming Zhao, Yulin Dai (2023). GRPa-PRS: A risk stratification method to identify genetically-regulated pathways in polygenic diseases .
Guangsheng Pei, Brisa S Fernandes, Yin-Ying Wang, Astrid M Manuel, Peilin Jia, Zhongming Zhao(2022). A single-cell atlas of the human brain in Alzheimer’s disease and its implications for personalized drug repositioning . Cold Spring Harbor Laboratory
CONFERENCE PAPER
Goncalves, Carlos-Alberto and Fernandes, Brisa and Nardin, Patricia and de Souza, Daniela Fraga(2015). PERIPHERAL BIOMARKERS FOR SCHIZOPHRENIA: DIAGNOSIS, PROGNOSIS AND FOLLOW-UP OF TREATMENT. SCHIZOPHRENIA BULLETIN. 41. p. S32--S32.
FERNANDES, B, BERK, M, ANDREAZZA, AC, et al.(2009). Brain-derived Neurotrophic Factor and Thiobarbituric Acid Reactive Substances Serum Levels in Chronicaly Medicated Schizophrenic Patients: A Positive Correlation. 64th Annual Convention of the Society-of-Biological-Psychiatry. 65. (8). p. 206S.
OLIVEIRA, G, FERNANDES, B, CERESER, KM, et al.(2009). Decreased Serum Brain-Derived Neurotrophic Factor in Unmedicated and Medicated Bipolar Patients in Manic and Depressive Episodes. 64th Annual Convention of the Society-of-Biological-Psychiatry. 65. (8). p. 132S.
OLIVEIRA, G, CERESER, KM, FERNANDES, B, FRIES, GR, STERTZ, L, AGUIAR, B, PFAENSELLER, B, KAPCZINSKI, F(2009). Decreased serum brain-derived neurotrophic factor in unmedicated and medicated bipolar patients during manic and depressive episodes. 8th International Conference on Bipolar Disorder. 11. p. 65-66.
DE LUCENA, D, FERNANDES, B, BERK, M, et al.(2009). Improvement of Schizophrenia Negative and Positive Symptoms With Memantine as Add-On Therapy to Clozapine: A Double-Blind, Randomized, Placebo-Controlled Trial. 64th Annual Convention of the Society-of-Biological-Psychiatry. 65. (8). p. 211S.
LUCENA, D, FERNANDES, B, BERK, M, DODD, S, MEDEIROS, DW, PEDRINI, M, KUNZ, M, GOMES, F, GIGLIO, L, LOBATO, MI, et al.(2009). Improvement of schizophrenia negative and positive symptoms with memantine as add-on therapy to clozapine: a double-blind, randomized, placebo-controlled trial. 8th International Conference on Bipolar Disorder. 11. p. 57.
FERNANDES, B, GONCALVES, DM, BRUNSTEIN, M, et al.(2007). The use of clozapine in the treatment of bipolar disorder in a patient with clinical comorbidities. International Conference on Bipolar Disorder. 9. p. 37-38.
BLACHER, C, NEUMANN, J, FERNANDES, B, et al.(2002). Off-pump coronary artery bypass surgery does not reduce lymphocyte activation. Congress of the European-Society-of-Cardiology. 23. p. 559.
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