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Hire Dr. Audrey G.

United States

Freelance science writer and editor. Expertise includes immunology, cancer biology, vaccines and pre-clinical trials. Over two decades biomedical research.

Profile Summary

I am very interested in the adaptive immune response to vaccines and cancer immunotherapy, including T cell responses, cytokines and other immune markers. I have been involved in several preclinical trials: an animal model of HIV and mouse models of breast, lung and bladder cancer. I enjoy strategizing on vaccine development, especially looking at novel immunogens, timing of prime and boosts, and adjuvant use. I have expertise in setting up experimental vaccine trials, including experimental and control groups, vaccine schedule, assays and analysis. I have set up preclinical trials, including those involving multi-valent vaccine strategies and studies combining tumor peptide vaccine with other therapies, such as adoptive cell transfer, chemotherapy and radiation. I am experienced at developing and optimizing immune assays, these include a flow cytometry based T-cell proliferation assay, CD4/CD8 T-cell ratios and ELISPOT. I have extensive experience in molecular biology, cell culture and biomarker discovery. I am very good at experimental designs and taking the next step in a project, as well as moving a project forward. I am very experienced at literature searches, data mining and I keep updated on the latest research in my field. • Immunology o Response to vaccines and immunotherapy • Vaccines o Primarily against viruses o Worked with lentivirus • Immunotherapy o Tumor peptide "vaccines" o Adoptive Cell Transfer • Cancer biology o Immune escape o Biomarkers in response to immunotherapy • Preclinical Trials o In vivo animal models of cancer o Feline model of HIV pathogenesis

Subject Matter Expertise

• ☆ Peptide Synthesis
• ☆ Microbiology
• ☆ Virology
• ☆ Retrovirology
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Data Mining
• ☆ Pathogenesis
• ☆ Cytometry
• ☆ Adoption
• ☆ Vaccine Development
• ☆ Oncology
• ☆ Immunotherapy
• ☆ Medical Writing

Services

• Writing
• Consulting
• Data & AI
• Product Development

Work Experience

Postdoctoral Scholar

University of California, Davis Health System

September 2011 - September 2013

Postdoctoral Fellow

University of Virginia

October 2009 - November 2010

Education

PhD (Veterinary Medicine and Epidemiology)

University of California Davis

August 1999 - March 2009

Bachelor of Science (Microbiology)

California State University System

September 1988 - August 1994

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Tam SM, Wadekar S, Clever JL, et al. The Effect of nef-Deleted SIV Administration on Disease Progression in SIV-Infected Rhesus Macaques. J HIV Retrovirus. 2016, 2:3.

(2013). Induction of Invasive Transitional Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A model for Immunotherapy Development . Journal of Visualized Experiments.

(2013). Antitumor effects of L-BLP25 Antigen-Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model . Journal of Translational Medicine, 2013, 11(1):64.

(2012). L-BLP25 vaccine plus letrozole for breast cancer: Is translation possible?. Oncoimmunology. 2012 Nov 1;1(8):1422-1424.

(2012). L-BLP25 vaccine plus letrozole induces a TH1 immune response and has additive antitumor activity in MUC1-expressing mammary tumors in mice. Clin Cancer Res. 2012 May 15;18(10):2861-71. Epub 2012 Mar 20.