Profile Details

Contact

★★★★★

☆☆☆☆☆

USD 150 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Atul Jain

United States

USD 150 /hr

Medicinal and Organic Chemist/Drug Discovery Scientist

Profile Summary

• 8+ years of experience in Medicinal/Organic Chemistry and Drug Design involving various therapeutic targets. Efficient in multi-step organic synthesis and optimizing druggable properties of target compounds • Excellent knowledge of identifying, executing and trouble-shooting synthetic routes for target molecules • Highly skilled in comprehensive purification and characterization of target molecules using CombiFlash, Prep HPLC, FT-IR, NMR (1H & 13C), HPLC (Shimadzu) and LC-MS (Shimadzu), HRMS (IT-TOF) (Shimadzu) • Knowledge and understanding in performing, outlining or interpreting biological/biochemical characterization of target molecules, thus providing effective communication and participation between various teams in drug discovery • Adept in conducting scientific information retrieval using SciFinder, Pubmed, and Reaxys and preliminary computational studies using MOE, SYBYL 8.1, and GOLD 5.0 • Conducted structure-activity relationship projects in various therapeutic areas including; smoking cessation, Alzheimer's, cancer, drugs of abuse and diabetes

Subject Matter Expertise

• ☆ Separation & Purification
• ☆ NMR Spectroscopy
• ☆ Liquid Chromatography/HPLC
• ☆ Organic Chemistry
• ☆ Biochemistry
• ☆ Medicinal Chemistry
• ☆ Research Methodology
• ☆ Innovation Management

Services

• Consulting
• Product development
• Data science & analysis
• Research

Research Secondary data compilation

Work Experience

Research Assoicate

Northwestern University

June 2016 - Present

Postdoctoral Research Associate

University of Illinois at Chicago

November 2013 - June 2016

Commercialization Strategy Consultant

EnterpriseWorks Chicago

February 2014 - July 2014

Commercialization Strategy Consultant

EnterpriseWorks Chicago

February 2014 - July 2014

Research Fellow

Virginia Commonwealth University

February 2013 - October 2013

Education

PhD (Medicinal Chemistry)

Virginia Commonwealth University

August 2008 - February 2013

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Wei, C., Bajpai, R., Sharma, H., Heitmeier, M., Jain, A.D., Matulis, S.M., Nooka, A.K., Mishra, R.K., Hruz, P.W., Schiltz, G.E., et al.(2017). Development of GLUT4-selective antagonists for multiple myeloma therapy . European Journal of Medicinal Chemistry. 139. p. 573-586.

Yao, Y., Kong, C., Yin, L., Jain, A.D., Ratia, K., Thatcher, G.R.J., Moore, T.W., Driver, T.G., Miller, L.W.(2017). Time-Gated Detection of Cystathionine γ-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor . Chemistry - A European Journal. 23. (4). p. 752-756.

Kolanos, R., Sakloth, F., Jain, A.D., Partilla, J.S., Baumann, M.H., Glennon, R.A.(2015). Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters . ACS Chemical Neuroscience. 6. (10). p. 1726-1731.

Jain, A.D., Potteti, H., Richardson, B.G., Kingsley, L., Luciano, J.P., Ryuzoji, A.F., Lee, H., Krunic, A., Mesecar, A.D., Reddy, S.P., et al.(2015). Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators . European Journal of Medicinal Chemistry. 103. p. 252-268.

Hamouda, A.K., Wang, Z.-J., Stewart, D.S., Jain, A.D., Glennon, R.A., Cohen, J.B.(2015). Desformylflustrabromine (dFBr) and [³H]dFBr-labeled binding sites in a nicotinic acetylcholine receptor . Molecular Pharmacology. 88. (1). p. 1-11.

Richardson, B.G., Jain, A.D., Speltz, T.E., Moore, T.W.(2015). Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway . Bioorganic and Medicinal Chemistry Letters. 25. (11). p. 2261-2268.

German, N., Kim, J.-S., Jain, A., Dukat, M., Pandya, A., Ma, Y., Weltzin, M., Schulte, M.K., Glennon, R.A.(2011). Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine . Journal of Medicinal Chemistry. 54. (20). p. 7259-7267.