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USD 65 /hr

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Hire Dr. Asanigari S.

India

USD 65 /hr

Genomics and epigenomics Bioinformatics scientists

Profile Summary

Distinguished Computational Biologist specializing in the epigenetic and genomic analysis of brain tumors, with a particular focus on deciphering the tumor microenvironment in glioblastoma and medulloblastoma to understand the interplay between neoplastic and immune cells in cancer progression and development. My doctoral research was centered on the investigation of mRNA and lncRNA genes across various cancer types, culminating in the development of a unified model for lncRNA regulation of protein-coding genes, employing a comprehensive systems biology approach. Equipped with a solid foundation in computational and systems biology from my academic training, I am deeply committed to the application of high-throughput sequencing technologies such as NGS, bulk RNA-seq, spatial and single-cell RNA-seq, DNA Methylation, Bisulfite sequencing, and ATAC-seq. My objective is to leverage these technologies to refine prognostic and diagnostic precision in oncology, thereby significantly enhancing patient survival and contributing to the advancement of personalized cancer therapy.

Subject Matter Expertise

• ☆ Computational Biology

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Non-Medical Regulatory Writing, Technical Writing, Creative Writing, General Proofreading & Editing

Research Market Research, User Research, Meta-Research, Feasibility Study, Technology Scouting, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

Work Experience

Postdoc(Visiting fellow)

National Cancer Institute

March 2020 - Present

Education

Ph.D. in Bioinformatics

University of Hyderabad

June 2015 - August 2019

Master of Science (M.Sc) (Biochemistry)

Yogi Vemana University

July 2010 - April 2012

Bachelor of Science (B.Sc) (Biotechnology)

Sri Krishnadevaraya University

July 2006 - May 2009

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Bharati Mehani and Saleembhasha Asanigari and Hye-Jung Chung and Karen Dazelle and Arashdeep Singh and Sridhar Hannenhalli and Kenneth Aldape(2022). Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology . Acta Neuropathologica Communications. 10. (1). Springer Science and Business Media {LLC}

Mehani, B., Asanigari, S., Chung, H.-J., Dazelle, K., Singh, A., Hannenhalli, S., Aldape, K.(2022). Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology . Acta Neuropathologica Communications. 10. (1).

Asanigari, Saleembhasha, Mehani, Bharati, Wu, Di, Chung, Hye-Jung, Aldape, Kenneth (2022). BIOLOGIC AND CLINICAL SIGNIFICANCE OF NEOPLASTIC AND IMMUNE CELL STATES IN GROUP3 AND GROUP 4 MEDULLOBLASTOMA . Neuro-Oncology.

(2019). Long non-coding RNAs as pan-cancer master gene regulators of associated protein-coding genes: a systems biology approach . PeerJ.

Saleembhasha, A., Mishra, S.(2019). Long non-coding RNAs as pan-cancer master gene regulators of associated protein-coding genes: A systems biology approach . PeerJ. 2019. (2).

(2018). Novel molecules lncRNAs, tRFs and circRNAs deciphered from next-generation sequencing/RNA sequencing: computational databases and tools . Briefings in functional genomics.

Saleembhasha, A., Mishra, S.(2018). Novel molecules lncRNAs, tRFs and circRNAs deciphered from next-generation sequencing/RNA sequencing: Computational databases and tools . Briefings in Functional Genomics. 17. (1). p. 15-25.