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Hire Apurva A.

India

USD 25 /hr

Ph.D. in Neuroscience with 10+ years of experience in Molecular Biology & Biostatistics

Profile Summary

1. National Brain Research Centre Master of Science and Doctor of Philosophy (Neuroscience) Scholar Aug 2011 - Jun 2022 · 10 yrs 11 mos Gurgaon, India The Ph.D. dissertation work involved the investigation on effects as well as the mechanisms of action of natural and chemical compounds for ameliorating the aetiological processes involved in Alzheimer’s disease (AD). The compounds studied, demonstrated potential effects against astrocyte-mediated neuroinflammation as well as in ameliorating the dysregulation in synaptic plasticity- and memory-relevant molecular signalling pathways, induced upon overexpression of amyloid precursor protein (APP) and co-expression of familial AD-linked Swedish APP and exon-9 deleted presenilin 1 (PS1) mutants.The Ph.D. dissertation work involved the investigation on effects as well as the mechanisms of action of natural and chemical compounds for ameliorating the aetiological processes involved in Alzheimer’s disease (AD). The compounds studied, demonstrated potential effects against astrocyte-mediated neuroinflammation as well as in ameliorating the dysregulation in synaptic plasticity- and memory-relevant molecular signalling pathways, induced upon overexpression of amyloid precursor protein (APP) and co-expression of familial AD-linked Swedish APP and exon-9 deleted presenilin 1 (PS1) mutants. Skills: Animal Cell Culture · Animal Behavior · BioAssays · Fluorescence Microscopy · Statistical Data Analysis · Molecular BiologySkills: Animal Cell Culture · Animal Behavior · BioAssays · Fluorescence Microscopy · Statistical Data Analysis · Molecular Biology 2. Jaypee Institute Of Information Technology Bachelor of Technology (Biotechnology) Scholar 2007 - 2011 · 4 yrs Noida, Uttar Pradesh, India Study of small structural proteins 6K and E3 of Chikungunya virusStudy of small structural proteins 6K and E3 of Chikungunya virus 3. RGCB - Rajiv Gandhi Centre for Biotechnology Internship TraineeInternship Trainee Jun 2010 - Jul 2010 · 2 mos Thiruvananthapuram, Kerala, IndiaThiruvananthapuram, Kerala, India The project dealt with the non-canonical activation of Notch signalling or target genes. The project involved the cloning and validation of a reporter vector having HES1 promoter with mutated CBF1 binding sites in a eukaryotic cell line. Earned experience in handling stem cell cultures; differentiated D3 mouse embryonic stem cells into neural progenitors.The project dealt with the non-canonical activation of Notch signalling or target genes. The project involved the cloning and validation of a reporter vector having HES1 promoter with mutated CBF1 binding sites in a eukaryotic cell line. Earned experience in handling stem cell cultures; differentiated D3 mouse embryonic stem cells into neural progenitors. 4. National Institute of Immunology (NII) Internship TraineeInternship Trainee Jun 2009 · 1 mo New Delhi, Delhi, IndiaNew Delhi, Delhi, India Gained basic practical experience in molecular biology methods such as affinity chromatography, primer designing, PCR, protein dialysis, agarose gel electrophoresis, etc.

Subject Matter Expertise

• ★ Molecular Neuroscience
• ☆ Neuroscience
• ☆ Systems Neuroscience

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, General Proofreading & Editing

Research User Research, Meta-Research, Feasibility Study, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Work Experience

n/a

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January 2023 - January 2023

Education

Ph.D. (Molecular Neuroscience)

National Brain Research Centre

August 2011 - June 2022

B. Tech (Biotechnology)

Jaypee Institute of Information Technology

July 2007 - May 2011

Certifications

• n/a

  n/a

  January 2023 - January 2023

Publications

JOURNAL ARTICLE

Deepali Singh and Apurva Agrawal and Chitra Mohinder Singh Singal and Hriday Shanker Pandey and Pankaj Seth and Shiv Kumar Sharma(2020). Sinomenine inhibits amyloid beta-induced astrocyte activation and protects neurons against indirect toxicity . Molecular Brain. 13. (1). Springer Science and Business Media {LLC}

Apurva Agrawal and Shweta Dang and Reema Gabrani(2012). Recent Patents on Anti-Telomerase Cancer Therapy . Recent Patents on Anti-Cancer Drug Discovery. 7. (1). p. 102--117. Bentham Science Publishers Ltd.

Akaash Kumar Mishra and Chakresh Kumar Jain and Apurva Agrawal and Saransh Jain Kumar Sambhav Jain and Namrata Dudha and Kapila Kumar and Sanjeev K. Sharma and Sanjay Gupta(2010). CHIKVPRO – a protein sequence annotation database for chikungunya virus . Bioinformation. 5. (1). p. 4--6. Biomedical Informatics

BOOK CHAPTER

Recent Advances in Anti-Telomerase Cancer Therapy @incollection{2014, doi = {10.2174/9781608059089114030019}, url = {https://doi.org/10.2174%2F9781608059089114030019}, year = 2014, month = {oct}, publisher = {{BENTHAM} {SCIENCE} {PUBLISHERS}}, pages = {581--631}, editor = {Apurva Agrawal and Shweta Dang and Reema Gabrani}, title = {Recent Advances in Anti-Telomerase Cancer Therapy}, booktitle = {Topics in Anti-Cancer Research}} . Topics in Anti-Cancer Research.