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Hire Dr. Antonio F.

Italy

USD 80 /hr

Researcher in neuroscience and human genetics, expert in cellular mechanisms and disease modeling.

Profile Summary

I am a neuroscientist and geneticist with extensive experience in neurodevelopmental disorders, cellular mechanisms, and translational research. My work focuses on understanding the molecular and cellular basis of rare and complex neurological diseases, integrating genetics, cellular biology, and advanced experimental models. I have led and collaborated on multiple research projects involving gene function analysis, disease modeling, and therapeutic target identification, with experience in both basic and applied research settings. My expertise includes experimental design, data analysis, and interpretation of results in the context of neurodevelopmental genetics and cellular neuroscience. In addition to my research, I have experience reviewing scientific manuscripts and grant proposals, mentoring students, and collaborating with interdisciplinary teams. I am proficient in translating complex scientific concepts into actionable insights, which is valuable for biotech, pharmaceutical, and investment clients seeking expert guidance in drug discovery, therapeutic development, and emerging technologies in neuroscience and genetics.

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Neuroscience
• ☆ Neurophysiology
• ☆ Developmental Neuroscience
• ☆ Pathogenesis
• ☆ Neurology
• ☆ Epilepsy & Seizures

Services

• Writing
• Research
• Consulting
• Product Development

Writing Non-Medical Regulatory Writing, Newswriting, General Proofreading & Editing, Translation

Research User Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting, Manufacturing Consulting

Product Development Product Evaluation, Product Validation, Concept Development

Work Experience

Istituto Giannina Gaslini

- Present

PostdoctoralResearcher

IRCCS Meyer Children Hospital

May 2017 - May 2023

Post Doctrol Fellow

INSERM

June 2013 - April 2017

Postdoc position

Research Fellow and Project Collaborator at the Laboratory of Experimental Medicine

January 2010 - April 2013

Education

Ph.D., Pharmacology

Drug Area and Innovative Treatments, University of Florence and Meyer University Hospital

January 2022 - January 2024

PhD Molecular Genetics

Specialization Diploma in Medical Genetics, University of Genoa

February 2006 - December 2009

Masters of Science

Master Degree in Biological Sciences, University of Genoa

January 2000 - February 2005

Certifications

• none

  None

  January 2026 - January 2026

Publications

JOURNAL ARTICLE

Antonio Falace, Léa Corbières, Lucas Silvagnoli, Cristiana Pelorosso, Clara Tuccari di San Carlo, Emmanuelle Buhler, Zeinab Hoteit, Sylvian Bauer, Beatrice Risso, Quenol Cesar, et al. (2025). Mosaic expression of SLC35A2 pathogenetic variants impairs neuronal migration and dendritogenesis in the developing cortex . Human Molecular Genetics.

Antonio Falace, Beatrice Risso, Antonella Riva, Greta Volpedo, Valerio Conti, Clara Tuccari di San Carlo, Federico Zara, Pasquale Striano (2025). SLC35A2-Related Brain Disorders: Genetics, Pathophysiology, and Therapeutic Insights . International Journal of Molecular Sciences.

Antonio Falace, Beatrice Risso, Antonella Riva, Greta Volpedo, Valerio Conti, Clara Tuccari di San Carlo, Federico Zara, Pasquale Striano (2025). <i>SLC35A2</i>-Related Brain Disorders: Genetics, Pathophysiology, and Therapeutic Insights . International Journal of Molecular Sciences.

Antonio Falace, Greta Volpedo, Marcello Scala, Federico Zara, Pasquale Striano, Anna Fassio (2024). V-ATPase Dysfunction in the Brain: Genetic Insights and Therapeutic Opportunities . Cells.

Antonio Falace, Greta Volpedo, Marcello Scala, Federico Zara, Pasquale Striano, Anna Fassio (2024). V-ATPase Dysfunction in the Brain: Genetic Insights and Therapeutic Opportunities . Cells.

Antonio Falace, Caterina Michetti, Fabio Benfenati, Anna Fassio(2022). Synaptic genes and neurodevelopmental disorders: From molecular mechanisms to developmental strategies of behavioral testing . Neurobiology of Disease. 173. p. 105856. Elsevier {BV}

Antonio Falace, Anna Fassio, Alessandro Esposito, Davide Aprile, Renzo Guerrini, Fabio Benfenati(2020). Emerging Role of the Autophagy/Lysosomal Degradative Pathway in Neurodevelopmental Disorders With Epilepsy . Frontiers in Cellular Neuroscience. 14. Frontiers Media {SA}

Antonio Falace, Alessandro Esposito, Matias Wagner, Moran Gal, Davide Mei, Valerio Conti, Tiziana Pisano, Davide Aprile, Maria Sabina Cerullo, Antonio De Fusco, et al.(2019). Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course . Brain. 142. (12). p. 3876--3891. Oxford University Press ({OUP})

Aprile, D., Fruscione, F., Baldassari, S., Fadda, M., Ferrante, D., Falace, A., Buhler, E., Sartorelli, J., Represa, A., Baldelli, P., et al.(2019). TBC1D24 regulates axonal outgrowth and membrane trafficking at the growth cone in rodent and human neurons . Cell Death and Differentiation.

Guarnieri, F.C., De Chevigny, A., Falace, A., Cardoso, C.(2018). Disorders of neurogenesis and cortical development . Dialogues in Clinical Neuroscience. 20. (4). p. 255-266.

Conti, V., Carabalona, A., Pallesi-Pocachard, E., Leventer, R.J., Schaller, F., Parrini, E., Deparis, A.A., Watrin, F., Buhler, E., Novara, F., et al.(2017). A novel strategy combining array-CGH, whole-exome sequencing and in utero electroporation in rodents to identify causative genes for brain malformations . Journal of Visualized Experiments. 2017. (130).

Mosca-Boidron, A.-L., Gueneau, L., Huguet, G., Goldenberg, A., Henry, C., Gigot, N., Pallesi-Pocachard, E., Falace, A., Duplomb, L., Thevenon, J., et al.(2016). A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability . European Journal of Human Genetics. 24. (6). p. 838-843.

Tagliatti, E., Fadda, M., Falace, A., Benfenati, F., Fassio, A.(2016). Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse . eLife. 5. (JANUARY2016).

Balestrini, S., Milh, M., Castiglioni, C., L&#252;thy, K., Finelli, M.J., Verstreken, P., Cardon, A., Stražišar, B.G., Holder, J.L., Lesca, G., et al.(2016). TBC1D24 genotype-phenotype correlation . Neurology. 87. (1). p. 77-85.

Vanni, N., Fruscione, F., Ferlazzo, E., Striano, P., Robbiano, A., Traverso, M., Sander, T., Falace, A., Gazzerro, E., Bramanti, P., et al.(2014). Impairment of ceramide synthesis causes a novel progressive myoclonus epilepsy . Annals of Neurology. 76. (2). p. 206-212.

Falace, A., Buhler, E., Fadda, M., Watrin, F., Lippiello, P., Pallesi-Pocachard, E., Baldelli, P., Benfenati, F., Zara, F., Represa, A., et al.(2014). TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway . Proceedings of the National Academy of Sciences of the United States of America. 111. (6). p. 2337-2342.

Falace, A., Vanni, N., Mallamaci, A., Striano, P., Zara, F.(2013). Do regulatory regions matter in FOXG1 duplications . European Journal of Human Genetics. 21. (4). p. 365-366.

Milh, M., Falace, A., Villeneuve, N., Vanni, N., Cacciagli, P., Assereto, S., Nabbout, R., Benfenati, F., Zara, F., Chabrol, B., et al.(2013). Novel Compound Heterozygous Mutations in TBC1D24 Cause Familial Malignant Migrating Partial Seizures of Infancy . Human Mutation. 34. (6). p. 869-872.

Striano, P., Coppola, A., Paravidino, R., Malacarne, M., Gimelli, S., Robbiano, A., Traverso, M., Pezzella, M., Belcastro, V., Bianchi, A., et al.(2012). Clinical significance of rare copy number variations in epilepsy: A case-control survey using microarray-based comparative genomic hybridization . Archives of Neurology. 69. (3). p. 322-330.

Falace, A., Filipello, F., La Padula, V., Vanni, N., Madia, F., De Pietri Tonelli, D., De Falco, F.A., Striano, P., Dagna Bricarelli, F., Minetti, C., et al.(2010). TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy . American Journal of Human Genetics. 87. (3). p. 365-370.

Falace, A., Striano, P., Manganelli, F., Coppola, A., Striano, S., Minetti, C., Zara, F.(2007). Inherited neuromyotonia: A clinical and genetic study of a family . Neuromuscular Disorders. 17. (1). p. 23-27.

Biancheri, R., Falace, A., Tessa, A., Pedemonte, M., Scapolan, S., Cassandrini, D., Aiello, C., Rossi, A., Broda, P., Zara, F., et al.(2007). POMT2 gene mutation in limb-girdle muscular dystrophy with inflammatory changes . Biochemical and Biophysical Research Communications. 363. (4). p. 1033-1037.

D&#39;Amico, A., Tessa, A., Bruno, C., Petrini, S., Biancheri, R., Pane, M., Pedemonte, M., Ricci, E., Falace, A., Rossi, A., et al.(2006). Expanding the clinical spectrum of POMT1 phenotype . Neurology. 66. (10). p. 1564-1567.

Biancheri, R., Bertini, E., Falace, A., Pedemonte, M., Rossi, A., D&#39;Amico, A., Scapolan, S., Bergamino, L., Petrini, S., Cassandrini, D., et al.(2006). POMGnT1 mutations in congenital muscular dystrophy: Genotype-phenotype correlation and expanded clinical spectrum . Archives of Neurology. 63. (10). p. 1491-1495.