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Hire Dr. Amy K.

Italy

USD 30 /hr

University of Oxford, PhD | freelance medical writer with expertise in immunology, transcriptomics and genome editing

Profile Summary

I completed my PhD at the University of Oxford as part of a 4-year Infection, Immunology and Translational Medicine Wellcome Trust PhD programme. During my PhD, I established a novel model in zebrafish that enables the genome-wide profiling of neutrophils and macrophages isolated directly from the in vivo context under different conditions of inflammation. I subsequently used the model to study myeloid-mediated inflammation in three different disease pathologies, the neutrophil response to Mycobacterium marinum, the earliest stages of melanoma and to study the role of macrophages in cardiac regeneration as part of a collaborative project. All three studies were published. The focus of my postdoctoral research is transcriptional reprogramming and epigenome editing of potential pathogenic regulatory regions in chronic inflammatory diseases in an effort to reprogramme disease signatures.

Subject Matter Expertise

• ☆ Genetics
• ☆ Transcriptomics
• ☆ Gene Editing/CRISPR

Services

• Writing

Writing Clinical Trial Documentation, Technical Writing

Work Experience

Freelance medical writer

infill healthcare communication

January 2019 - December 2019

Postdoctoral researcher

Humanitas University

May 2017 - December 2019

Postdoctoral researcher

University of Oxford

January 2016 - April 2017

Education

PhD

University of Oxford

October 2011 - October 2015

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2018). Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes . Disease Models & Mechanisms.

(2017). Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum . Scientific Reports.

(2017). Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma . Genes & Development.

(2014). Hsp90 Binds Directly to Fibronectin (FN) and Inhibition Reduces the Extracellular Fibronectin Matrix in Breast Cancer Cells . PLoS ONE.

(2013). A Real Time Chemotaxis Assay Unveils Unique Migratory Profiles amongst Different Primary Murine Macrophages . PLoS ONE.