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Hire Dr. Amrutha S.

Israel

Profile Summary

Ph.D level molecular biologist with a background of genetics, biochemistry and molecular biology and deep interest in neural differentiation. Worked on conditional knockout mice to understand behaviour, stem cells and developing zebrafish to test enzyme inhibitors for their effect on neural differentiation, and on protein-protein interactions.

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Stem Cell Research
• ☆ Protein/Enzyme Engineering
• ☆ Neurology

Services

• Writing
• Consulting
• Product Development

Work Experience

Post-doctoral researcher

Weizmann Institute of Science

March 2018 - Present

Post-doctoral researcher

Weizmann Institute of Science

March 2018 - Present

Post-doctoral fellow

Centre de recherche du CHUM

November 2016 - January 2018

Post-doctoral researcher

CRCHUM

November 2016 - January 2018

Ph.D student

JNCASR

August 2010 - July 2016

Education

Ph.D (Molecular Biology and Genetics Unit)

Jawaharlal Nehru Centre for Advanced Scientific Research

August 2010 - October 2016

M.Sc (School of Biological Sciences)

Madurai Kamaraj University

August 2008 - July 2010

B.Sc (SIES College, Microbiology and Biotechnology Departments)

University of Mumbai

June 2005 - April 2008

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2019). The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation . Frontiers in Molecular Neuroscience.

Swaminathan, A., Hassan-Abdi, R., Renault, S., Siekierska, A., Riché, R., Liao, M., de Witte, P. A. M., Yanicostas, C., Soussi-Yanicostas, N., Drapeau, P., et al.(2018). Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development . Curr Biol.

Swaminathan, A., Bouffard, M., Liao, M., Ryan, S., Callister, J. B., Pickering-Brown, S. M., Armstrong, G. A. B., Drapeau, P.(2018). Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model . Hum Mol Genet. 27. (10). p. 1754-1762.

Dhanasekaran, K., Bose, A., Rao, V. J., Boopathi, R., Shankar, S. R., Rao, V. K., Swaminathan, A., Vasudevan, M., Taneja, R., Kundu, T. K.(2018). Unraveling the role of aurora A beyond centrosomes and spindle assembly: implications in muscle differentiation . FASEB J. p. fj201800997.

Samarut, É, Swaminathan, A., Riché, R., Liao, M., Hassan-Abdi, R., Samarut, É, Swaminathan, A., Riché, R., Liao, M., Hassan-Abdi, R., et al.(2018). γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment . Epilepsia. 59. (11). p. 2061-2074.

Swaminathan, A., Delage, H., Chatterjee, S., Belgarbi-Dutron, L., Swaminathan, A., Delage, H., Chatterjee, S., Swaminathan, A., Delage, H., Chatterjee, S., et al.(2016). Transcriptional Coactivator and Chromatin protein, PC4, is involved in Hippocampal Neurogenesis and Spatial Memory Extinction . J Biol Chem.

Dhanasekaran, K., Kumari, S., Boopathi, R., Shima, H., Swaminathan, A., Bachu, M., Ranga, U., Igarashi, K., Kundu, T. K.(2016). Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes . FEBS J. 283. (6). p. 968-85.

Selvi, R. B., Swaminathan, A., Chatterjee, S., Shanmugam, M. K., Li, F., Ramakrishnan, G. B., Siveen, K. S., Chinnathambi, A., Zayed, M. E., Selvi, R. B., et al.(2015). Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model . Oncotarget. 6. (41). p. 43806-18.

Swaminathan, A., Kumar, M., Halder Sinha, S., Schneider-Anthony, A., Swaminathan, A., Kumar, M., Halder Sinha, S., Schneider-Anthony, A., Boutillier, A. L., Kundu, T. K.(2014). Modulation of neurogenesis by targeting epigenetic enzymes using small molecules: an overview . ACS Chem Neurosci. 5. (12). p. 1164-77.

Selvi, B. R., Swaminathan, A., Maheshwari, U., Nagabhushana, A., Mishra, R. K., Kundu, T. K.(2014). CARM1 regulates astroglial lineage through transcriptional regulation of Nanog and posttranscriptional regulation by miR92a . Mol Biol Cell. 26. (2). p. 316-26.

Schneider, A., Chatterjee, S., Bousiges, O., Selvi, B. R., Swaminathan, A., Cassel, R., Blanc, F., Kundu, T. K., Boutillier, A. L.(2013). Acetyltransferases (HATs) as targets for neurological therapeutics . Neurotherapeutics. 10. (4). p. 568-88.

Kumari, S., Swaminathan, A., Chatterjee, S., Kumari, S., Swaminathan, A., Chatterjee, S., Senapati, P., Boopathi, R., Kundu, T. K.(2013). Chromatin organization, epigenetics and differentiation: an evolutionary perspective . Subcell Biochem. 61. p. 3-35.