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Profile Details
Subject Matter Expertise
Services
Work Experience
University of Pittsburgh
- Present 
Research Assistant Professor
University of Pittsburgh
August 2019 - Present
Research Associate
University of Pittsburgh
October 2016 - July 2019
Postdoctoral Associate
University of Pittsburgh School of Medicine
January 2013 - September 2016
Education
Doctor of Philosophy
Griffith University
February 2009 - November 2012
Doctor of Philosophy (PhD) (Griffith Health Institute)
Griffith University - Gold Coast Campus
February 2009 - November 2012
BBiomedSc (Hons; First Class) (Griffith Health Institute)
Griffith University - Gold Coast Campus
February 2004 - July 2008
BBiomedSc (Hons; First Class)
Griffith University
February 2004 - July 2008
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Amanda M Clark, Nancy L Allbritton, Alan Wells(2020). Integrative microphysiological tissue systems of cancer metastasis to the liver . Seminars in Cancer Biology. Elsevier {BV}
(2019). The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment . Seminars in cancer biology.
(2019). Adult Stem Cell Functioning in the Tumor Micro-Environment . International journal of molecular sciences.
(2018). The great escape: How metastases of melanoma, and other carcinomas, avoid elimination . Experimental biology and medicine (Maywood, N.J.).
(2018). Statins attenuate outgrowth of breast cancer metastases . British journal of cancer.
(2018). A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures . Molecular & cellular proteomics : MCP.
(2017). Liver 'organ on a chip' . Experimental cell research.
(2017). Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy . British journal of cancer.
(2017). Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells . Molecular cancer.
(2017). A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms . Stem cell reviews and reports.
(2016). A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties . Lab on a chip.
(2016). Liver protects metastatic prostate cancer from induced death by activating E-cadherin signaling . Hepatology (Baltimore, Md.).
(2016). Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells . BMC cancer.
(2016). Liver metastases: Microenvironments and ex-vivo models . Experimental biology and medicine (Maywood, N.J.).
(2015). Immunomodulatory activity of Melaleuca alternifolia concentrate (MAC): inhibition of LPS-induced NF-κB activation and cytokine production in myeloid cell lines . International immunopharmacology.
(2015). Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells . PloS one.
Masashi Furukawa, Sarah Wheeler, Amanda M. Clark, Alan Wells, Rajeev Samant(2015). Lung Epithelial Cells Induce Both Phenotype Alteration and Senescence in Breast Cancer Cells . {PLoS} {ONE}. 10. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e0118060. Public Library of Science ({PLoS})
S E Wheeler, A M Clark, D P Taylor, C L Young, V C Pillai, D B Stolz, R Venkataramanan, D Lauffenburger, L Griffith, A Wells(2014). Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system . British Journal of Cancer. 111. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2342--2350. Nature Publishing Group
A. M. Clark, S. E. Wheeler, D. P. Taylor, V. C. Pillai, C. L. Young, R. Prantil-Baun, T. Nguyen, D. B. Stolz, J. T. Borenstein, D. A. Lauffenburger, et al.(2014). A microphysiological system model of therapy for liver micrometastases . Experimental Biology and Medicine. 239. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1170--1179. {SAGE} Publications
Amanda Clark, Donald P. Taylor, Sarah Wheeler, Alan Wells(2014). Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition . Breast Cancer Res Treat. 144. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 551--560. Springer Science $\mathplus$ Business Media
Rachel E. Horton, Gary D. Grant, Ben Matthews, Michael Batzloff, Suzzanne J. Owen, Stephanie Kyan, Cameron P. Flegg, Amanda M. Clark, Glen C. Ulett, Nigel Morrison, et al.(2013). Quorum Sensing Negatively Regulates Multinucleate Cell Formation during Intracellular Growth of Burkholderia pseudomallei in Macrophage-Like Cells . {PLoS} {ONE}. 8. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e63394. Public Library of Science ({PLoS})
Sarah E Wheeler, Jeffrey T Borenstein, Amanda M Clark, Mohammed Ebrahimkhani, Ira J Fox, Linda Griffith, Walker Inman, Douglas Lauffenburger, Transon Nguyen, Venkateswaran C Pillai, et al.(2013). All-human microphysical model of metastasis therapy . Stem Cell Res Ther. 4. (Suppl 1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString S11. Springer Science $\mathplus$ Business Media
Koichi Ito, Kimberley Stannard, Elwyn Gabutero, Amanda M. Clark, Shi-Yong Neo, Selda Onturk, Helen Blanchard, Stephen J. Ralph(2012). Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment . Cancer Metastasis Rev. 31. (3-4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 763--778. Springer Science $\mathplus$ Business Media
Ratings and Comments
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