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Hire Dr. Alexander L.

United States

USD 300 /hr

Bioinformatics Expert

Profile Summary

I am a computational evolutionary biologist and bioinformatician with expertise spanning molecular evolution, viral genomics, metagenomics, and machine learning–driven predictive biology. My research focuses on understanding and forecasting how viruses, microbes, and cancers evolve across molecular, ecological, and planetary scales. I am currently a Postdoctoral Associate at Weill Cornell Medicine and serve as Executive Director and Director of Bioinformatics for the MetaSUB Consortium, a global initiative mapping microbial and viral diversity across more than 200 cities.

Subject Matter Expertise

• ★ Evolutionary Biology
• ★ Genomics
• ★ Bioinformatics
• ☆ Molecular Biology
• ☆ Omics
• ☆ Molecular Evolution
• ☆ Machine Learning
• ☆ Ecology
• ☆ R
• ☆ Gap Analysis

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing

Research Technology Scouting, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Business Strategy Consulting, Go-to-Market Strategy Consulting, Healthcare Consulting, Operations Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis

Product Development Product Evaluation

Work Experience

Postdoctoral Associate

Weill Cornell Medicine

July 2023 - Present

PhD Student

Temple University

2018 - 2023

Education

PhD

Temple University

August 2018 - May 2023

Certifications

• NA

  NA

  January 2025 - January 2025

Publications

PREPRINT

Alexander Lucaci, Christopher Mason (2025). Diversity and Distinctive Characteristics of the Global RNA Virome in Urban Environments .

Avery Selberg, Nathan L Clark, Timothy B Sackton, Spencer V Muse, Alexander G Lucaci, Steven Weaver, Anton Nekrutenko, Maria Chikina, Sergei L Kosakovsky Pond (2025). Minus the Error: Testing for Positive Selection in the Presence of Residual Alignment Errors .

Avery Selberg, Nathan L Clark, Timothy B Sackton, Spencer V Muse, Alexander G Lucaci, Steven Weaver, Anton Nekrutenko, Maria Chikina, Sergei L Kosakovsky Pond (2025). Minus the Error: Testing for Positive Selection in the Presence of Residual Alignment Errors .

Avery Selberg, Nathan L Clark, Timothy B Sackton, Spencer V Muse, Alexander G Lucaci, Steven Weaver, Anton Nekrutenko, Maria Chikina, Sergei L. Kosakovsky Pond (2024). Minus the Error: Testing for Positive Selection in the Presence of Residual Alignment Errors .

Alexander G Lucaci, William E Brew, Sergei L Kosakovsky Pond, Anna R Moore (2023). Evolutionary analysis of mammalian Rem2, a member of the RGK (Rem, Rem2, Rad, and Gem/Kir) family of small GTPases, reveals the role of selection and epistasis in shaping protein functional constraints .

Jordan D. Zehr, Sergei L. Kosakovsky Pond, Jean K. Millet, Ximena A. Olarte-Castillo, Alexander G. Lucaci, Stephen D. Shank, Kristina M. Ceres, Annette Choi, Gary R. Whittaker, Laura B. Goodman, et al. (2023). Natural selection differences detected in key protein domains between non-pathogenic and pathogenic Feline Coronavirus phenotypes .

Alexander G Lucaci, Jordan D Zehr, David Enard, Joseph W. Thornton, Sergei L. Kosakovsky Pond (2022). Evolutionary shortcuts via multi-nucleotide substitutions and their impact on natural selection analyses .

Rainer Benndorf, Ryan Velazquez, Jordan D. Zehr, Sergei Kosakovsky Pond, Jody L. Martin, Alexander G. Lucaci (2022). Human HspB1, HspB3, HspB5 and HspB8: Shaping these Disease Factors during Vertebrate Evolution .

Alexander G Lucaci, Michael J Notaras, Sergei L Kosakovsky Pond, Dilek Colak(2022). The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease? . Cold Spring Harbor Laboratory

Alexander G Lucaci, Jordan D Zehr, Stephen D Shank, Dave Bouvier, Han Mei, Anton Nekrutenko, Darren P Martin, Sergei L Kosakovsky Pond(2022). RASCL: Rapid Assessment Of SARS-CoV-2 Clades Through Molecular Sequence Analysis . Cold Spring Harbor Laboratory

Alexander G Lucaci, Sadie R Wisotsky, Stephen D. Shank, Steven Weaver, Sergei L. Kosakovsky Pond (2020). Extra base hits: widespread empirical support for instantaneous multiple-nucleotide changes .

JOURNAL ARTICLE

Alexander G Lucaci, Jordan D Zehr, David Enard, Joseph W Thornton, Sergei L Kosakovsky Pond, Kelley Harris (2023). Evolutionary Shortcuts via Multinucleotide Substitutions and Their Impact on Natural Selection Analyses . Molecular Biology and Evolution.

Jordan D Zehr, Sergei L Kosakovsky Pond, Jean K Millet, Ximena A Olarte-Castillo, Alexander G Lucaci, Stephen D Shank, Kristina M Ceres, Annette Choi, Gary R Whittaker, Laura B Goodman, et al. (2023). Natural selection differences detected in key protein domains between non-pathogenic and pathogenic feline coronavirus phenotypes . Virus Evolution.

RASCL: Rapid Assessment of Selection in CLades through molecular sequence analysis <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . PLOS ONE.

Rainer Benndorf, Ryan Velazquez, Jordan D. Zehr, Sergei L. Kosakovsky Pond, Jody L. Martin, Alexander G. Lucaci (2022). Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution . Cell Stress and Chaperones.

Alexander G. Lucaci, Marc Robinson-Rechavi, Sadie R. Wisotsky, Stephen D. Shank, Steven Weaver, Sergei L. Kosakovsky Pond (2021). Extra base hits: Widespread empirical support for instantaneous multiple-nucleotide changes . PLOS ONE.