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Hire Dr. Akhileshwar S.

India

USD 15 /hr

Freelance life science research, books and grant writer with 11+year experience in cancer and phytochemicals research

Profile Summary

I have completed my Research Associateship (ICMR) at CSIR-CFTRI, India on the project “Unravel the anticancerous role of curcumin biotransformed targeting tumor suppressor protein p53 in gastric cancer”. I completed my undergraduate (BS) and post-graduate (MS) degrees in First Class from Banaras Hindu University (BHU), Varanasi, India. I joined the PhD program at BHU after competing in a nationally held CSIR-UGC (NET) examination in India in which I was awarded for Junior Research Fellowship. My research specialization is primarily in genetics, metabolomics, bioinformatics, molecular biology and histopathological evaluations, which I am sure, will be adaptable to many challenges in biological researches. I investigated the therapeutic properties of curcumin and its metabolites especially their inhibitory potential on the CagA oncoprotein in HER2 associated-gastric cancer. Currently, I have 21-peer reviewed publications, 2-author books, 3-edited books, 13-book chapters and several meeting presentations at local and international scientific meetings.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Botany
• ☆ Pollen & Spores
• ☆ Ethnobotany
• ☆ Plant Pathology
• ☆ Plant Breeding & Genetics
• ☆ Plant Physiology
• ☆ Phytochemistry
• ☆ Medicinal Plants
• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Phycology/Algae
• ☆ Mycology/Fungi
• ☆ Virology
• ☆ Coronaviruses
• ☆ Retrovirology
• ☆ Industrial Microbiology
• ☆ Microbiological Assays
• ☆ Bacteriology
• ☆ Gram-Negative Bacteria
• ☆ Gram-Positive Bacteria
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cytogenetics
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Mycology
• ☆ Histology
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Pathogenesis
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cytometry

Services

• Writing

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing

Work Experience

ICMR-RA

CSIR-CFTRI

June 2019 - Present

Education

PhD

Banaras Hindu University, Varanasi, India

November 2010 - August 2015

Certifications

• Project Management

  CSIR-Central Food Technological Research Institute, Mysore, India.

  June 2019 - June 2021

Publications

JOURNAL ARTICLE

Akhileshwar Kumar SRIVASTAVA, Sunil L., Gayathri THULASY, Subrahmaniam Gandhi DOSS, Divya SINGH (2025). Cutting-edge extraction technologies for anticancer compounds from ethnomedicinal mulberry: A molecular review in cancer management . Notulae Scientia Biologicae.

Akhileshwar Kumar Srivastava, Divya Singh, Priya Yadav, Monika Singh, Sandeep Kumar Singh, Ajay Kumar (2023). Paradigm of Well-Orchestrated Pharmacokinetic Properties of Curcuminoids Relative to Conventional Drugs for the Inactivation of SARS-CoV-2 Receptors: An In Silico Approach . Stresses.

Akhileshwar Kumar Srivastava, Divya Singh, Priya Yadav, Monika Singh, Sandeep Kumar Singh, Ajay Kumar (2023). Paradigm of Well-Orchestrated Pharmacokinetic Properties of Curcuminoids Relative to Conventional Drugs for the Inactivation of SARS-CoV-2 Receptors: An In Silico Approach . Stresses.

Dikshansha Rohilla, Akhileshwar Kumar Srivastava, Rahul Prasad Singh, Priya Yadav, Sandeep Kumar Singh, Dharmendra Kumar, Nikunj Bhardwaj, Mahipal Singh Kesawat, Kapil Deo Pandey, Ajay Kumar (2023). Algae Polysaccharides (Carrageenan and Alginate)—A Treasure-Trove of Antiviral Compounds: An In Silico Approach to Identify Potential Candidates for Inhibition of S1-RBD Spike Protein of SARS-CoV2 . Stresses.

Dikshansha Rohilla, Akhileshwar Kumar Srivastava, Rahul Prasad Singh, Priya Yadav, Sandeep Kumar Singh, Dharmendra Kumar, Nikunj Bhardwaj, Mahipal Singh Kesawat, Kapil Deo Pandey, Ajay Kumar (2023). Algae Polysaccharides (Carrageenan and Alginate)—A Treasure-Trove of Antiviral Compounds: An In Silico Approach to Identify Potential Candidates for Inhibition of S1-RBD Spike Protein of SARS-CoV2 . Stresses.

Srivastava, A.K., Singh, D., Yadav, P., Singh, M., Singh, S.K., Kumar, A.(2023). Paradigm of Well-Orchestrated Pharmacokinetic Properties of Curcuminoids Relative to Conventional Drugs for the Inactivation of SARS-CoV-2 Receptors: An In Silico Approach . Stresses. 3. (3). p. 615-628.

Rohilla, D., Srivastava, A.K., Singh, R.P., Yadav, P., Singh, S.K., Kumar, D., Bhardwaj, N., Kesawat, M.S., Pandey, K.D., Kumar, A.(2023). Algae Polysaccharides (Carrageenan and Alginate)—A Treasure-Trove of Antiviral Compounds: An In Silico Approach to Identify Potential Candidates for Inhibition of S1-RBD Spike Protein of SARS-CoV2 . Stresses. 3. (3). p. 555-569.

Acar, A., Singh, D., Srivastava, A.K.(2022). Assessment of the ameliorative effect of curcumin on pendimethalin-induced genetic and biochemical toxicity . Scientific Reports. 12. (1).

Manu Kumar, Sandeep Kumar Singh, Prem Pratap Singh, Vipin Kumar Singh, Avinash Chandra Rai, Akhileshwar Kumar Srivastava, Livleen Shukla, Mahipal Singh Kesawat, Atul Kumar Jaiswal, Sang-Min Chung, et al. (2021). Potential Anti-Mycobacterium tuberculosis Activity of Plant Secondary Metabolites: Insight with Molecular Docking Interactions . Antioxidants.

Manu Kumar, Sandeep Kumar Singh, Prem Pratap Singh, Vipin Kumar Singh, Avinash Chandra Rai, Akhileshwar Kumar Srivastava, Livleen Shukla, Mahipal Singh Kesawat, Atul Kumar Jaiswal, Sang-Min Chung, et al. (2021). Potential Anti-<i>Mycobacterium tuberculosis</i> Activity of Plant Secondary Metabolites: Insight with Molecular Docking Interactions . Antioxidants.

Nandini P. Shetty, Manoj Prabhakaran, Akhileshwar Kumar Srivastava(2021). Pleiotropic nature of curcumin in targeting multiple apoptotic‐mediated factors and related strategies to treat gastric cancer: A review . Phytotherapy Research. 35. (10). p. 5397--5416. Wiley

Kumar, M., Singh, S.K., Singh, P.P., Singh, V.K., Rai, A.C., Srivastava, A.K., Shukla, L., Kesawat, M.S., Kumar Jaiswal, A., Chung, S.-M., et al.(2021). Potential anti-mycobacterium tuberculosis activity of plant secondary metabolites: Insight with molecular docking interactions . Antioxidants. 10. (12).

Shetty, N.P., Prabhakaran, M., Srivastava, A.K.(2021). Pleiotropic nature of curcumin in targeting multiple apoptotic-mediated factors and related strategies to treat gastric cancer: A review . Phytotherapy Research. 35. (10). p. 5397-5416.

(2020). Assessment of malathion toxicity on cytophysiological activity, DNA damage and antioxidant enzymes in root of Allium cepa model . Scientific Reports.

(2020). Molecular fossils “pseudogenes” as functional signature in biological system . Genes & Genomics.

Singh, R.K., Singh, D., Yadava, A., Srivastava, A.K.(2020). Molecular fossils “pseudogenes” as functional signature in biological system . Genes and Genomics. 42. (6). p. 619-630.

Srivastava, A.K., Singh, D.(2020). Assessment of malathion toxicity on cytophysiological activity, DNA damage and antioxidant enzymes in root of Allium cepa model . Scientific Reports. 10. (1).

Singh, R.K., Ranjan, A., Srivastava, A.K., Singh, M., Shukla, A.K., Atri, N., Mishra, A., Singh, A.K., Singh, S.K.(2020). Cytotoxic and apoptotic inducing activity of Amoora rohituka leaf extracts in human breast cancer cells . Journal of Ayurveda and Integrative Medicine. 11. (4). p. 383-390.

(2019). Cytotoxic and apoptotic inducing activity of Amoora rohituka leaf extracts in human breast cancer cells . Journal of Ayurveda and Integrative Medicine.

(2018). Structure-based analysis of curcumin and conventional drugs targeting tumor-inducing protein PHF20 . Bioinformation.

(2018). Distribution of cyanobacteria and their interactions with pesticides in paddy field: A comprehensive review . Journal of Environmental Management.

(2018). Biotechnological aspects of plants metabolites in the treatment of ulcer: A new prospective . Biotechnology Reports.

Singh, A.K., Singh, S.K., Singh, P.P., Srivastava, A.K., Pandey, K.D., Kumar, A., Yadav, H.(2018). Biotechnological aspects of plants metabolites in the treatment of ulcer: A new prospective . Biotechnology Reports. 18.

Singh, A.K., Singh, P.P., Tripathi, V., Verma, H., Singh, S.K., Srivastava, A.K., Kumar, A.(2018). Distribution of cyanobacteria and their interactions with pesticides in paddy field: A comprehensive review . Journal of Environmental Management. 224. p. 361-375.

(2017). Structural Interactions of Curcumin Biotransformed Molecules with the N-Terminal Residues of Cytotoxic-Associated Gene A Protein Provide Insights into Suppression of Oncogenic Activities . Interdisciplinary Sciences: Computational Life Sciences.

Srivastava, A.K., Singh, D., Roy, B.K.(2017). Structural Interactions of Curcumin Biotransformed Molecules with the N-Terminal Residues of Cytotoxic-Associated Gene A Protein Provide Insights into Suppression of Oncogenic Activities . Interdisciplinary Sciences: Computational Life Sciences. 9. (1). p. 116-129.

(2015). HER2 Expression in Gastric and Gastroesophageal Cancer: Report from a Tertiary Care Hospital in North India . Indian Journal of Surgery.

(2015). Insights from the molecular docking of curcumin to the virulent factors of Helicobacter pylori . Bioinformation.

(2015). In SilicoProfiling of the Potentiality of Curcumin and Conventional Drugs for CagA Oncoprotein Inactivation . Archiv der Pharmazie.

Srivastava, A.K., Tewari, M., Shukla, H.S., Roy, B.K.(2015). In Silico Profiling of the Potentiality of Curcumin and Conventional Drugs for CagA Oncoprotein Inactivation . Archiv der Pharmazie. 348. (8). p. 548-555.

Srivastava, A.K., Singh, D., Tewari, M., Shukla, H.S., Roy, B.K.(2014). Impact of turmeric as dietary approach on HER2 status in blood of gastric cancer patients . International Journal of Phytomedicine. 6. (2). p. 293-299.

BOOK CHAPTER

Sunil, L., Sadashivaiah, Chandrakanth, R., Srivastava, A.K., Shivakumara, C.S.(2024). Advancement of Analytical Techniques in Some Ethnomedicinal Plants: Current and Future Perspectives . Ethnomedicinal Plants for Drug Discovery Current Developments. p. 545-557.

Ahirwar, R.K., Srivastava, A.K., Yadav, D., Bhoi, D.K., Jangde, R.(2024). Exploration of Ethnomedicinal Plants for Drug Discovery in High-Throughput Omics Era . Ethnomedicinal Plants for Drug Discovery Current Developments. p. 423-442.

Mishra, A., Jaiswal, P., Srivastava, A.K., Singh, D.(2023). Aquaporins Gene Expression in Plants Under Stress Condition . Stress Responsive Factors and Molecular Farming in Medicinal Plants. p. 193-205.

Srivastava, A.K., Chatterjee, I., Mishra, S., Tripathi, V., Zehra, W., Chakrwal, K., Agrawal, V.(2023). Role of miRNA in Medicinal Plants Under Stress Condition . Stress Responsive Factors and Molecular Farming in Medicinal Plants. p. 141-153.

Srivastava, A.K., Mishra, P., Mishra, A.K.(2020). Effect of climate change on plant secondary metabolism: An ecological perspective . Evolutionary Diversity as A Source for Anticancer Molecules. p. 47-76.

(2020). Endophytic bacteria as a source of bioactive compounds . Microbial Endophytes.

Srivastava, A.K., Yadava, A., Singh, D.(2020). Evolutionary mechanism for biosynthesis of diverse molecules . Evolutionary Diversity as A Source for Anticancer Molecules. p. 1-27.

(2020). Fungi as potential candidates for bioremediation . Abatement of Environmental Pollutants.

Srivastava, A.K., Singh, R.K., Singh, D.(2020). Microbe-based bioreactor system for bioremediation of organic contaminants: Present and future perspective . Microbe Mediated Remediation of Environmental Contaminants. p. 241-253.

Singh, R.K., Ranjan, A., Singh, M., Srivastava, A.K.(2020). Anticancer natural product from marine invertebrates . Evolutionary Diversity as A Source for Anticancer Molecules. p. 255-266.

Monika, R., Singh, R.K., Shrivastava, A., Yadav, A., Srivastava, A.K.(2019). Endophytic bacteria as a source of bioactive compounds . Microbial Endophytes Prospects for Sustainable Agriculture. p. 175-188.

Singh, R.K., Tripathi, R., Ranjan, A., Srivastava, A.K.(2019). Fungi as potential candidates for bioremediation . Abatement of Environmental Pollutants Trends and Strategies. p. 177-191.

(2019). PGPR Bioelicitors . PGPR Amelioration in Sustainable Agriculture.

(2019). The role of fungus in bioactive compound production and nanotechnology . Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology.

Srivastava, A.K.(2019). The role of fungus in bioactive compound production and nanotechnology . Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology. p. 145-162.

(2018). Significance of medicinal plants in human life . Synthesis of Medicinal Agents from Plants.

BOOK

Srivastava, A.K., Ahirwar, R.K., Yadav, D., Kumar, D.G.(2024). Ethnomedicinal Plants for Drug Discovery: Current Developments . Ethnomedicinal Plants for Drug Discovery Current Developments. p. 1-557.

Srivastava, A.K., Ahirwar, R.K., Yadav, D., Kumar, D.G.(2024). Preface . Ethnomedicinal Plants for Drug Discovery Current Developments. p. v-vi.

Srivastava, A.K., Singh, D., Singh, R.K.(2023). DRUG-DELIVERY SYSTEMS OF PHYTOCHEMICALS AS THERAPEUTIC STRATEGIES IN CANCER THERAPY . Drug Delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy. p. 1-248.

Singh, D., Mishra, A.K., Srivastava, A.K.(2023). Preface . Stress Responsive Factors and Molecular Farming in Medicinal Plants. p. v-vi.

Singh, D., Mishra, A.K., Srivastava, A.K.(2023). Stress-responsive Factors and Molecular Farming in Medicinal Plants . Stress Responsive Factors and Molecular Farming in Medicinal Plants. p. 1-377.

Srivastava, A.K., Kumar, D., Singh, D., Singh, R.K.(2022). Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology . Xenobiotics in Chemical Carcinogenesis Translational Aspects in Toxicology. p. 1-314.

Srivastava, A.K., Kannaujiya, V.K., Singh, R.K., Singh, D.(2020). Evolutionary Diversity as a Source for Anticancer Molecules . Evolutionary Diversity as A Source for Anticancer Molecules. p. 1-369.

PREPRINT

Akhileshwar Srivastava, Divya Singh (2020). Destabilizing the Structural Integrity of SARS-CoV2 Receptor Proteins by Curcumin Along with Hydroxychloroquine: An Insilco Approach for a Combination Therapy .

Akhileshwar Kumar Srivastava, Divya Singh (2020). Detection of HER2 expression and its structural alterations in gastric cancer tissues infected with cagA+H. pylori .

OTHER

Singh, R.K., Ranjan, A., Tripathi, R., Srivastava, A.K., Singh, M., Kumar, A., Singh, A.K., Dwivedi, K.N., Atri, N., Singh, S.K.(2020). Virtual screening of MAP-Tau protein inhibitors from Semecarpus anacardium Linn. leaf extract for cancer prevention . Biorxiv.

Srivastava, A.K., Singh, D.(2020). Destabilizing the structural integrity of SARS-CoV2 receptor proteins by curcumin along with hydroxychloroquine: An Insilco approach for a combination therapy . Chemrxiv.

Srivastava, A.K., Singh, D.(2020). Detection of HER2 expression and its structural alterations in gastric cancer tissues infected with cagA+ H. pylori . Biorxiv.