Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 55 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Ailin L.

Australia

USD 55 /hr

Immunology and Cell Biology Consultant | 15+ years of expertise in Infection, Autoimmunity, Vaccines & Immunotherapy

Profile Summary

I am a Senior Research Fellow at Griffith University and an expert in translational research, developing vaccines and immunotherapies for infection, autoimmunity, and cancer. I have extensive experience across all phases of research—from conceptualization and experimental design to methodology development, scientific writing, and successful grant acquisition, including competitive funding as lead investigator from the Heart Foundation, Leducq Foundation, NHMRC, and Advance Queensland. I have authored 40 peer-reviewed publications, including 11 first-author and 5 senior-author papers in journals such as Immunity, Cancer Discovery, Nature Communications, and Clinical Cancer Research. My work bridges fundamental science and clinical application, advancing innovative vaccines and immunotherapies to address critical gaps in disease prevention and treatment. In addition to a strong scientific background and broad exposure to diverse research areas, I bring ten years of experience as a freelance science editor and writer. I am available to provide expert consultation on a wide range of projects, offering both technical insight and practical guidance.

Subject Matter Expertise

• ☆ Microbiology
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Stem Cell Research
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Pathogenesis
• ☆ Clinical Microbiology
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ 3D Cell Culture
• ☆ Cytometry
• ☆ Cell Aging

Services

• Writing
• Research
• Consulting

Writing Technical Writing, Creative Writing, General Proofreading & Editing

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

Work Experience

Senior Research Fellow

Griffith University

March 2020 - Present

Research Officer/Senior Research Officer

QIMR Berghofer, Australia

October 2015 - February 2020

Education

PhD

Monash University

January 2012 - March 2015

Certifications

• Certification details not provided.

Publications

CONFERENCE PAPER

Ailin Lepletier, Michael F. Good, Manisha Pandey, Simone Reynolds, Victoria Ozberk, Vanessa Meier-Stephenson, Michael Hawkes, Ainslie Calcutt, Christie Short, Ijeoma Ogbuehi, et al. (2025). Phase I Trial of a Peptide-Based Vaccine to Prevent Group A Streptococcal Infection .

Ailin Lepletier, Rukshan Ahamed Mohamed Rafeek, Despena Vedis, Harshi Weerakoon, Natkunam Ketheesan, Michael F. Good, Manisha Pandey (2025). Low-Dose Interleukin-2 Therapy: A Transformative Approach for the Management of Autoimmune Complications Associated with Streptococcus pyogenes Infections .

JOURNAL ARTICLE

Ailin Lepletier, Michael F. Good, Manisha Pandey, Simone Reynolds, Victoria Ozberk, Vanessa Meier-Stephenson, Michael Hawkes, Ainslie Calcutt, Christie Short, Ijeoma Ogbuehi, et al. (2025). Phase I Trial of a Peptide-Based Vaccine to Prevent Group A Streptococcal Infection . Proceedings.

Ailin Lepletier, Rukshan Ahamed Mohamed Rafeek, Despena Vedis, Harshi Weerakoon, Natkunam Ketheesan, Michael F. Good, Manisha Pandey (2025). Low-Dose Interleukin-2 Therapy: A Transformative Approach for the Management of Autoimmune Complications Associated with <i>Streptococcus pyogenes</i> Infections . Proceedings.

Ailin Lepletier, Rukshan Ahamed Mohamed Rafeek, Natkunam Ketheesan, Michael F. Good, Manisha Pandey, Stefan H. E. Kaufmann (2025). Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease . mBio.

Rafeek RAM, Ketheesan N, Good MF, Pandey M, Lepletier A(2025). Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease . mBio.

A phase 1 randomized controlled trial of a peptide-based group A streptococcal vaccine in healthy volunteers @article{Meier_Stephenson_2024, title={A phase 1 randomized controlled trial of a peptide-based group A streptococcal vaccine in healthy volunteers}, volume={25}, ISSN={1745-6215}, url={http://dx.doi.org/10.1186/s13063-024-08634-4}, DOI={10.1186/s13063-024-08634-4}, number={1}, journal={Trials}, publisher={Springer Science and Business Media LLC}, author={Meier-Stephenson, Vanessa and Hawkes, Michael T. and Burton, Catherine and Calcutt, Ainslie and Davis, Chris and Dooley, Jessica and Good, Michael and Houghton, Michael and Keeffe, Eloise and Kim, Kelly and Lepletier, Ailin and O’Neil, Conar and Ogbuehi, Ijeoma and Ozberk, Victoria and Pandey, Manisha and Reynolds, Simone and Seth, Avi and Stokes, William and Tse-Chang, Alena and Tyrrell, Ben and Tyrrell, D. Lorne and Tyrrell, Gregory J. and Yaskina, Maryna}, year={2024}, month=nov } . Trials.

Ailin Lepletier, Harshi Weerakoon, John J. Miles, Michelle M. Hill (2024). A shotgun proteomic dataset of human mucosal-associated invariant T cells . Data in Brief.

Mills JL, Lepletier A, Ozberk V, Dooley J, Kaden J, Calcutt A, Huo Y, Hicks A, Zaid A, Good MF, et al. (2024). Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive <i>Streptococcus pyogenes</i> infection . Frontiers in immunology.

Weerakoon H, Mohamed A, Wong Y, Chen J, Senadheera B, Haigh O, Watkins TS, Kazakoff S, Mukhopadhyay P, Mulvenna J, et al. (2024). Integrative temporal multi-omics reveals uncoupling of transcriptome and proteome during human T cell activation . NPJ systems biology and applications.

Mills, J.-L., Lepletier, A., Ozberk, V., Dooley, J., Kaden, J., Calcutt, A., Huo, Y., Hicks, A., Zaid, A., Good, M.F., et al.(2024). Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection . Frontiers in Immunology. 15.

Weerakoon, H., Mohamed, A., Wong, Y., Chen, J., Senadheera, B., Haigh, O., Watkins, T.S., Kazakoff, S., Mukhopadhyay, P., Mulvenna, J., et al.(2024). Integrative temporal multi-omics reveals uncoupling of transcriptome and proteome during human T cell activation . npj Systems Biology and Applications. 10. (1).

Meier-Stephenson, V., Hawkes, M.T., Burton, C., Calcutt, A., Davis, C., Dooley, J., Good, M., Houghton, M., Keeffe, E., Kim, K., et al.(2024). A phase 1 randomized controlled trial of a peptide-based group A streptococcal vaccine in healthy volunteers . Trials. 25. (1).

Weerakoon, H., Miles, J.J., Hill, M.M., Lepletier, A.(2024). A shotgun proteomic dataset of human mucosal-associated invariant T cells . Data in Brief. 56.

Ailin Lepletier, Victoria Ozberk, Mehfuz Zaman, Sharareh Eskandari, Jacqualine Kaden, Jamie-Lee Mills, Ainslie Calcutt, Jessica Dooley, Yongbao Huo, Emma L. Langshaw, et al. (2023). A Glycolipidated-liposomal peptide vaccine confers long-term mucosal protection against Streptococcus pyogenes via IL-17, macrophages and neutrophils . Nature Communications.

Ailin Lepletier, Simone Reynolds, Rukshan Ahamed Mohamed Rafeek, Adam Hamlin, Manisha Pandey, Natkunam Ketheesan, Michael F. Good (2023). Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model . npj Vaccines.

Reynolds, S., Rafeek, R.A.M., Hamlin, A., Lepletier, A., Pandey, M., Ketheesan, N., Good, M.F.(2023). Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model . npj Vaccines. 8. (1).

Savino, W., Lepletier, A.(2023). Thymus-derived hormonal and cellular control of cancer . Frontiers in Endocrinology. 14.

Ozberk, V., Zaman, M., Lepletier, A., Eskandari, S., Kaden, J., Mills, J.-L., Calcutt, A., Dooley, J., Huo, Y., Langshaw, E.L., et al.(2023). A Glycolipidated-liposomal peptide vaccine confers long-term mucosal protection against Streptococcus pyogenes via IL-17, macrophages and neutrophils . Nature Communications. 14. (1).

Ailin Lepletier, Harshi Weerakoon, John J. Miles, Michelle M. Hill (2022). A high-resolution mass spectrometry based proteomic dataset of human regulatory T cells . Data in Brief.

Weerakoon, H., Miles, J.J., Lepletier, A., Hill, M.M.(2022). A high-resolution mass spectrometry based proteomic dataset of human regulatory T cells . Data in Brief. 40.

Kolka, C.M., Webster, J., Lepletier, A., Winterford, C., Brown, I., Richards, R.S., Zelek, W.M., Cao, Y., Khamis, R., Shanmugasundaram, K.B., et al.(2022). C5b-9 Membrane Attack Complex Formation and Extracellular Vesicle Shedding in Barrett’s Esophagus and Esophageal Adenocarcinoma . Frontiers in Immunology. 13.

Weerakoon H, Straube J, Lineburg K, Cooper L, Lane S, Smith C, Alabbas S, Begun J, Miles JJ, Hill MM, et al.(2021). Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity . Clinical & translational immunology.

Ailin Lepletier, Manisha Pandey, Victoria Ozberk, Sharareh Eskandari, Ahmed O Shalash, Michael A Joyce, Holly A Saffran, Christopher J Day, Belinda L Spillings, Jamie‐Lee Mills, et al.(2021). Antibodies to neutralising epitopes synergistically block the interaction of the receptor‐binding domain of SARS‐CoV‐2 to ACE 2 . Clinical & Translational Immunology. 10. (3). Wiley

Pandey, M., Ozberk, V., Eskandari, S., Shalash, A.O., Joyce, M.A., Saffran, H.A., Day, C.J., Lepletier, A., Spillings, B.L., Mills, J.-L., et al.(2021). Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2 . Clinical and Translational Immunology. 10. (3).

A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Scientific Data.

Braun M, Aguilera AR, Sundarrajan A, Corvino D, Stannard K, Krumeich S, Das I, Lima LG, Meza Guzman LG, Li K, et al.(2020). CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8⁺ T Cells . Immunity.

Lepletier A, Madore J, O&#39;Donnell JS, Johnston RL, Li XY, McDonald E, Ahern E, Kuchel A, Eastgate M, Pearson SA, et al.(2020). Tumor CD155 Expression Is Associated with Resistance to Anti-PD1 Immunotherapy in Metastatic Melanoma . Clinical cancer research : an official journal of the American Association for Cancer Research.

Weerakoon, H., Potriquet, J., Shah, A.K., Reed, S., Jayakody, B., Kapil, C., Midha, M.K., Moritz, R.L., Lepletier, A., Mulvenna, J., et al.(2020). A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics . Scientific Data. 7. (1).

Li XY, Moesta AK, Xiao C, Nakamura K, Casey M, Zhang H, Madore J, Lepletier A, Aguilera AR, Sundarrajan A, et al.(2019). Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor Immunity . Cancer discovery.

Lepletier A, Hun ML, Hammett MV, Wong K, Naeem H, Hedger M, Loveland K, Chidgey AP(2019). Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging . Cell reports.

Mittal D, Lepletier A, Madore J, Aguilera AR, Stannard K, Blake SJ, Whitehall VLJ, Liu C, Bettington ML, Takeda K, et al.(2019). CD96 Is an Immune Checkpoint That Regulates CD8⁺ T-cell Antitumor Function . Cancer immunology research.

Lepletier A, Lutzky VP, Mittal D, Stannard K, Watkins TS, Ratnatunga CN, Smith C, McGuire HM, Kemp RA, Mukhopadhyay P, et al.(2018). The immune checkpoint CD96 defines a distinct lymphocyte phenotype and is highly expressed on tumor-infiltrating T cells . Immunology and cell biology.

Oliveira-de-Abreu E, Silva-Dos-Santos D, Lepletier A, Ramos TDP, Ferreira-Reis R, Vasconcelos-Fontes L, Ramos MT, Torres RC, Cotta-de-Almeida V, Villa-Verde DMS(2018). Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery . Frontiers in endocrinology.

Golbert DCF, Santana-Van-Vliet E, Ribeiro-Alves M, Fons&#234;ca MMBD, Lepletier A, Mendes-da-Cruz DA, Loss G, Cotta-de-Almeida V, Vasconcelos ATR, Savino W(2017). Small interference ITGA6 gene targeting in the human thymic epithelium differentially regulates the expression of immunological synapse-related genes . Cell adhesion & migration.

(2017). Inflammation and Thymus Ageing . Frontiers of hormone research.

Lepletier, A., Alsharif, A., Chidgey, A.P.(2017). Inflammation and Thymus Ageing . Frontiers of hormone research. 48. p. 19-36.

Barsanti M, Lim JM, Hun ML, Lister N, Wong K, Hammett MV, Lepletier A, Boyd RL, Giudice A, Chidgey AP(2016). A novel Foxn1^eGFP/+ mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations . European journal of immunology.

Savino W, Mendes-da-Cruz DA, Lepletier A, Dardenne M(2015). Hormonal control of T-cell development in health and disease . Nature reviews. Endocrinology.

Lepletier A, Chidgey AP, Savino W(2015). Perspectives for Improvement of the Thymic Microenvironment through Manipulation of Thymic Epithelial Cells: A Mini-Review . Gerontology.

Lepletier A, de Almeida L, Santos L, da Silva Sampaio L, Paredes B, Gonz&#225;lez FB, Freire-de-Lima CG, Beloscar J, Bottasso O, Einicker-Lamas M, et al.(2014). Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease . PLoS neglected tropical diseases.

The role of brain angiotensin converting enzyme on the nocturnal thirst and sodium appetite in ovariectomized rats (683.6) @article{Reis_2014, title={The role of brain angiotensin converting enzyme on the nocturnal thirst and sodium appetite in ovariectomized rats (683.6)}, volume={28}, ISSN={1530-6860}, url={http://dx.doi.org/10.1096/fasebj.28.1_supplement.683.6}, DOI={10.1096/fasebj.28.1_supplement.683.6}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Reis, Luis and Lepletier, Ailin and Mecawi, Andre and Fonseca, Fabricia and Araujo, Iracema and Almeida‐Pereira, Gislaine and Antunes‐Rodrigues, Jose}, year={2014}, month=apr } . The FASEB Journal.

Lepletier, A., Villar, S.R., P&#233;rez, A.R., Morrot, A., Savino, W.(2014). Stress related hormonal circuitry in chagas disease . Advances in Neuroimmune Biology. 5. (2). p. 91-98.

Lepletier A, de Carvalho VF, Rodrigues e Silva PM, Villar S, P&#233;rez AR, Savino W, Morrot A(2013). Trypanosoma cruzi disrupts thymic homeostasis by altering intrathymic and systemic stress-related endocrine circuitries . PLoS neglected tropical diseases.

Villar SR, Ronco MT, Fern&#225;ndez Bussy R, Roggero E, Lepletier A, Manarin R, Savino W, P&#233;rez AR, Bottasso O(2013). Tumor necrosis factor-α regulates glucocorticoid synthesis in the adrenal glands of Trypanosoma cruzi acutely-infected mice. the role of TNF-R1 . PloS one.

Lepletier A, de Frias Carvalho V, Morrot A, Savino W(2012). Thymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones . Annals of the New York Academy of Sciences.

P&#233;rez AR, Berbert LR, Lepletier A, Revelli S, Bottasso O, Silva-Barbosa SD, Savino W(2012). TNF-α is involved in the abnormal thymocyte migration during experimental Trypanosoma cruzi infection and favors the export of immature cells . PloS one.

Mecawi AS, Lepletier A, Araujo IG, Fonseca FV, Reis LC(2008). Oestrogenic influence on brain AT1 receptor signalling on the thirst and sodium appetite in osmotically stimulated and sodium-depleted female rats . Experimental physiology.

Mecawi AS, Lepletier A, Araujo IG, Olivares EL, Reis LC(2007). Assessment of brain AT1-receptor on the nocturnal basal and angiotensin-induced thirst and sodium appetite in ovariectomised rats . Journal of the renin-angiotensin-aldosterone system : JRAAS.

Cedraz-Mercez PL, Mecawi AS, Lepletier A, Ara&#250;jo IG, Costa-e-Sousa RH, Rocha FF, Olivares EL, Medeiros MA, Reis LC(2007). Noradrenergic stimulation within midbrain raphe increases electrolyte excretion in rats . Experimental physiology.

PREPRINT

Ailin Lepletier, Manisha Pandey, Despena Vedis, Victoria Ozberk, Merrina Anugraham, Darrell Bassette, Ainslie Calcutt, Hannah Frost, Kristy Azzopardi, Andrew Steer, et al. (2025). Subclinical exposure to Streptococcus pyogenes drives the development of long-lived immunity .

Ailin Lepletier, Despena Vedis, Vicky Ozberk, Merrina Anugraham, Darrell Bassette, Ainslie Callcutt, Hannah R. Frost, Kristy I. Azzopardi, Andrew C. Steer, Daniel Kolarich, et al. (2025). Sub-clinical exposure to <i>Streptococcus pyogenes</i> drives the development of immunity .

Ailin Lepletier, Rukshan Ahamed Mohamed Rafeek, Natkunam Ketheesan, Michael F. Good, Manisha Pandey (2024). Immunotherapeutic strategy to prevent progression and complications of acute rheumatic fever .

CONFERENCE PRESENTATION

Lepletier A. (2024). Immunotherapeutic strategy to treat acute rheumatic fever and rheumatic heart disease . 2024 QCVRN and Heart Foundation Research Showcase.

Lepletier A. (2024). Peptide-Based Novel Vaccine Strategies to Combat Streptococcal Infections . 2024 Queensland Immunology Networking Symposium.

Lepletier A. (2024). Low-dose interleukin 2 therapy halts the progression of rheumatic heart disease . ASI Clinical Translational School.

Lepletier A. (2023). Streptococcus pyogenes infection of the respiratory tract elicits cross-compartmental immune responses . 22nd Brisbane Immunology Group (BIG) Retreat.

Lepletier A. (2021). Multi-omics analysis of the immune system: unrevealing the role of CD49f in regulatory T cells. Queensland Mass Spectrometry Symposium.

Lepletier A. (2019). Resistance to immunotherapy is associated with high parenchymal PD1+CD8+/CD8+ T cells (PD1tR) driven by tumour CD155 . ESMO Immuno-Oncology Congress 2019.

Lepletier A. (2019). Tumor CD155 expression limits sensitivity to anti-PD1-based immunotherapy in metastatic melanoma and NSCLC. 3rd Brisbane Immunotherapy Conference.

Lepletier A. (2012). Immature thymocytes are released into the periphery of Trypanosoma cruzi acutely infected mice by a S1P-dependent mechanism. 10th International Congress on Cell Biology.

Lepletier A. (2007). Role of prolactin and glucocorticoid receptor interactions in the thymus atrophy occurring during experimental Trypanosoma cruzi infection. 8º Congress of the International Society of Neuroimmunomodulation.

PATENT

Lepletier A. (2024). Treatment methods for autoimmune diseases.

BOOK CHAPTER

Weerakoon, H., Lepletier, A.(2024). Role of regulatory T cells in pathogenesis and therapeutics of Crohn’s disease and ulcerative colitis . Regulatory T cells and Autoimmune Diseases. p. 351-386.

OTHER

Rafeek, R.A.M., Ketheesan, N., Good, M.F., Pandey, M., Lepletier, A.(2024). Immunotherapeutic strategy to prevent progression and complications of acute rheumatic fever . bioRxiv.

Weerakoon, H., Mohamed, A., Wong, Y., Senadheera, B., Haigh, O., Watkins, T.S., Kazakoff, S., Mukhopadhyay, P., Mulvenna, J., Miles, J.J., et al.(2023). Integrative proteomics and transcriptomics of human T-cells reveals temporal metabolic reprogramming following TCR-induced activation . bioRxiv.

Mills, J.-L., Lepletier, A., Ozberk, V., Dooley, J., Kaden, J., Calcutt, A., Huo, Y., Hicks, A., Zaid, A., Good, M.F., et al.(2023). Disruption of IL-17 signaling in the respiratory mucosa results in invasive streptococcal infection . bioRxiv.

Data from CD96 Is an Immune Checkpoint That Regulates CD8&lt;sup&gt;+&lt;/sup&gt; T-cell Antitumor Function @article{Mittal_2023, title={Data from CD96 Is an Immune Checkpoint That Regulates CD8&lt;sup&gt;+&lt;/sup&gt; T-cell Antitumor Function}, url={http://dx.doi.org/10.1158/2326-6066.c.6550068.v1}, DOI={10.1158/2326-6066.c.6550068.v1}, publisher={American Association for Cancer Research (AACR)}, author={Mittal, Deepak and Lepletier, Ailin and Madore, Jason and Aguilera, Amelia Roman and Stannard, Kimberley and Blake, Stephen J. and Whitehall, Vicki L.J. and Liu, Cheng and Bettington, Mark L. and Takeda, Kazuyoshi and Long, Georgina V. and Scolyer, Richard A. and Lan, Ruth and Siemers, Nathan and Korman, Alan and Teng, Michele W.L. and Johnston, Robert J. and Dougall, William C. and Smyth, Mark J.}, year={2023}, month=apr } .

Disruption of IL-17 signaling in the respiratory mucosa results in invasive streptococcal infection @article{Mills_2023, title={Disruption of IL-17 signaling in the respiratory mucosa results in invasive streptococcal infection}, url={http://dx.doi.org/10.1101/2023.11.10.566548}, DOI={10.1101/2023.11.10.566548}, publisher={Cold Spring Harbor Laboratory}, author={Mills, Jamie-Lee and Lepletier, Ailin and Ozberk, Victoria and Dooley, Jessica and Kaden, Jacqualine and Calcutt, Ainslie and Huo, Yongbao and Hicks, Allan and Zaid, Ali and Good, Michael F. and Pandey, Manisha}, year={2023}, month=nov } .

Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity @article{Weerakoon_2021, title={Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity}, url={http://dx.doi.org/10.1101/2021.02.22.432185}, DOI={10.1101/2021.02.22.432185}, publisher={Cold Spring Harbor Laboratory}, author={Weerakoon, Harshi and Straube, Jasmin and Lineburg, Katie and Cooper, Leanne and Lane, Steven and Smith, Corey and Alabbas, Saleh and Begun, Jakob and Miles, John J and Hill, Michelle M and Lepletier, Ailin}, year={2021}, month=feb } .

CONFERENCE POSTER

Lepletier A. (2023). Immune mechanisms of protection against Streptococcus pyogenes infection: vaccination with GAS vax . 51st ASI Annual Scientific Meeting.

Lepletier A. (2023). Modelling S. pyogenes infection of the URT to reveal mechanisms of site-specific and cross-compartment immunity and to support vaccine development . Asia-Pacific Vaccine and Immunotherapy Congress.

Lepletier A. (2022). Integrative proteomics and transcriptomics of human T-cells reveals temporal changes in metabolic pathways following TCR-mediated activation . Multi-Omics Inaugural Conference.

Lepletier A. (2022). Controlled Human Infection for Vaccination Against Streptococcus Pyogenes (CHIVAS) - challenge study with M75 . 2022 Lancefield International Symposium on Streptococci and Streptococcal Diseases.

Lepletier A. (2021). Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity. ASI Annual Scientific Meeting.

Lepletier A. (2019). Tumor-intrinsic CD155 expression limits sensitivity to immunotherapy in advanced metastatic melanoma and lung cancer patients. ASI Annual Scientific Meeting.

Lepletier A. (2017). Human immune cell expression of CD96, a potential checkpoint inhibitor and target for cancer immunotherapy. 46th Annual Scientific Meeting of Australasian Society for Immunology.

Lepletier A. (2016). Inhibition of angiotensin converting enzime decreases nocturnal sodium appetite in ovariectomized rats. XXII Latin-american and 1rst Ibero-american Congress of Physiological Sciences.

Lepletier A. (2016). Thymic epithelial cell activation following sex steroid blockage. International Congress of Immunology.

Lepletier A. (2012). Trypanosoma cruzi subverts thymic homeostasis by altering intrathymic and systemic endocrine status. ThymUS 2012 International Conference.

PUBLIC SPEECH

Lepletier A. (2020). Next generation of immune checkpoint therapy in cancer: targeting the CD155 pathway. Kymab Discovery Meeting.

Lepletier A. (2020). The next generation of immune checkpoint therapy in cancer: targeting the CD155 pathway. Griffith University MSC/HDR Seminar series.

Lepletier A. (2019). Cancer treatment in the era of immune checkpoint blockage therapy. University of Queensland PDN Post doc development network.

CONFERENCE OUTPUT

(2019). Resistance to immunotherapy is associated with high parenchymal PD1+CD8+/CD8+ T cells (PD1tR) driven by tumour CD155 . ESMO IMMUNO-ONCOLOGY CONGRESS 2019.