Profile Details

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USD 80 /hr

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☆☆☆☆☆

Hire Dr. Ace S.

United States

USD 80 /hr

Biochemistry, Microbiology, and Cell Biology expert with 15 years of experience in biotech and academia.

Profile Summary

I have a PhD in Chemistry and Chemical Biology from Cornell University, focusing on Biophysical Chemistry, a Postdoctoral Research Fellowship in Microbiology and Biochemistry from Harvard Medical School, a teaching position in Biochemistry at UC San Diego, and a Science Communication (IMPACT) Fellowship from MIT. Experienced Ph.D. Biochemist, Biophysicist, and Microbiologist with expertise in elucidating protein and gene function. Adept at solving complex problems using experimental methods of protein biochemistry, transcription regulation, RNA expression, and protein-protein or protein-nucleic acid interactions to understand protein and gene function in cellular physiology. Notable discoveries include transcription regulation and membrane protein assembly mechanisms. Specialized skills: assay development, fluorescence microscopy, immunofluorescence (IF), protein characterization (design/expression/purification/validation), Western blot, molecular biology, microbiology, single-cell analysis, NGS, spatial proteomics, spatial transcriptomics, clinical diagnostics, and computing (MATLAB, R, Python). With these methods, a comprehensive understanding of disease can be achieved to develop more effective and safer therapeutics.

Subject Matter Expertise

• ★ Microbiology
• ★ Biochemistry
• ★ Molecular Biology
• ☆ Binding Assays
• ☆ RNA Sequencing
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Gene Regulation
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Clinical Laboratory Science
• ☆ Clinical Biochemistry

Services

• Writing
• Research

Writing Medical Writing, Technical Writing

Research Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Work Experience

Postdoctoral Fellow

Harvard Medical School

June 2017 - Present

Scientists

10x Genomics

August 2021 - October 2024

Senior Biochemist

Siemens Healthineers

March 2020 - August 2021

Postdoctoral Associate

Cornell University

August 2016 - April 2017

Education

Master of Science (Chemistry and Chemical Biology)

Cornell University

- Present

Bachelor of Science (Chemistry)

University of the Philippines Diliman

- Present

Doctor of Philosophy (Chemistry and Chemical Biology)

Cornell University

- Present

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Won Jung, Tai-Yen Chen, Ace George Santiago, Peng Chen (2024). Memory effects of transcription regulator−DNA interactions in bacteria . Proceedings of the National Academy of Sciences.

(2017). Adaptor protein mediates dynamic pump assembly for bacterial metal efflux . Proceedings of the National Academy of Sciences.

(2016). Single-molecule dynamics of the molecular chaperone trigger factor in living cells . Molecular Microbiology.

(2015). Quantifying Multistate Cytoplasmic Molecular Diffusion in Bacterial Cells via Inverse Transform of Confined Displacement Distribution . The Journal of Physical Chemistry B.

(2015). Metalloregulator CueR biases RNA polymerase’s kinetic sampling of dead-end or open complex to repress or activate transcription . Proceedings of the National Academy of Sciences.

(2015). Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells . Nature Communications.

(2013). Single-Molecule Dynamics and Mechanisms of Metalloregulators and Metallochaperones . Biochemistry.