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Hire Alexandro Martagon - MD PhD - MCTM C.

Mexico

Assistant Professor l Clinical Research l Medical Translation l Scientific Speaker

Profile Summary

Medical doctor and scientist focused on translating biomedical research into real benefits for patients through healthcare improvements. Master’s degree obtained at University of St. Thomas Houston and continuous education at Harvard Medical School. More than 10 years of national and international experience in basic research, academic, and pharmaceutical industry clinical protocols for metabolic diseases such as obesity, diabetes, and dyslipidemias, in public and private sectors. Assistant Professor in a top private university in Mexico and Latin America reaching hundreds of students as a bilingual speaker. Scientific and academic practice focused on safety, quality, informatics, and leadership in multifunctional teams, facilitating interaction with medical and scientific key opinion leaders in diverse forums. Self-motivated, professionally growth driven through compliance and ethics.

Subject Matter Expertise

• ☆ Leadership
• ☆ Drug Development
• ☆ Preclinical Research
• ☆ Pharmacovigilance/Drug Safety Monitoring
• ☆ Diabetes
• ☆ Obesity
• ☆ Health Informatics
• ☆ Healthcare Administration & Management
• ☆ Healthcare Quality Improvement

Services

• Writing

Writing Clinical Trial Documentation, Medical Writing

Work Experience

Investigador en Ciencias Médicas C

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran

March 2019 - Present

Affiliated Assistant Professor

Tecnológico de Monterrey

August 2017 - Present

Profesor Investigador

Tecnologico de Monterrey

July 2017 - Present

Clinical Research Scientist

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

February 2016 - Present

Education

Safety, Quality, Informatics and Leadership

Harvard Medical School

May 2021 - May 2022

Master in Clinical Translation Management (Business Graduate School )

University of St. Thomas

January 2018 - December 2018

MD (Escuela de Medicina )

Instituto Tecnológico y de Estudios Superiores de Monterrey

August 2006 - January 2016

PhD (Genomics)

Houston Methodist Research Institute

January 2011 - December 2013

Licenciado en Biociencias

Instituto Tecnológico y de Estudios Superiores de Monterrey

August 2006 - December 2010

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Alexandro J. Martagón, Carlos A. Fermín-Martínez, Neftali Eduardo Antonio-Villa, Roopa Mehta, Paloma Almeda-Valdés, Arsenio Vargas-Vázquez, Liliana Muñoz-Hernández, Donají V. Gómez-Velasco, Daniel Elías-López, Gabriela A. Galán-Ramírez, et al. (2022). Arterial Stiffness and HbA1c: Association Mediated by Insulin Resistance in Hispanic Adults . International Journal of Environmental Research and Public Health.

Alexandro Martagon, Carlos A. Fermín-Martínez, Neftali Eduardo Antonio-Villa, Roopa Mehta, Paloma Almeda-Valdes, Arsenio Vargas-Vázquez, Liliana Muñoz-Hernández, Donají V. Gómez-Velasco, Daniel Elías-López, Gabriela Galan-Ramirez, et al. (2022). Arterial Stiffness and HbA1c: Association Mediated by Insulin Resistance in Hispanic Adults . International Journal of Environmental Research and Public Health.

Magdalena Del Rocio Sevilla-Gonzalez, Brigette Bourguet-Ramirez, Laura Sofia Lazaro-Carrera, Alexandro J Martagon-Rosado, Donaji Veronica Gomez-Velasco, Tannia Leticia Viveros-Ruiz(2022). Evaluation of a Web Platform to Record Lifestyle Habits in Subjects at Risk of Developing Type 2 Diabetes in a Middle-Income Population: Prospective Interventional Study . JMIR Diabetes. {JMIR} Publications Inc.

Mehta, R., Elías-López, D., Martagón, A.J., Pérez-Méndez, O.A., Sánchez, M.L.O., Segura, Y., Tusié, M.T., Aguilar-Salinas, C.A.(2021). LCAT deficiency: a systematic review with the clinical and genetic description of Mexican kindred . Lipids in Health and Disease. 20. (1).

Elías-López, D., Vargas-Vázquez, A., Mehta, R., Cruz Bautista, I., Del Razo Olvera, F., Gómez-Velasco, D., Almeda Valdes, P., Aguilar-Salinas, C.A., Arellano-Campos, O., Bello-Chavolla, O.Y., et al.(2021). Natural course of metabolically healthy phenotype and risk of developing Cardiometabolic diseases: a three years follow-up study . BMC Endocrine Disorders. 21. (1).

Cruz-Bautista, I., Huerta-Chagoya, A., Moreno-Macías, H., Rodríguez-Guillén, R., Ordóñez-Sánchez, M.L., Segura-Kato, Y., Mehta, R., Almeda-Valdés, P., Gómez-Munguía, L., Ruiz-De Chávez, X., et al.(2021). Familial hypertriglyceridemia: an entity with distinguishable features from other causes of hypertriglyceridemia . Lipids in Health and Disease. 20. (1).

Antonio-Villa, N.E., Bello-Chavolla, O.Y., Vargas-Vázquez, A., Mehta, R., Fermín-Martínez, C.A., Martagón-Rosado, A.J., Barquera-Guevara, D.A., Aguilar-Salinas, C.A., Arellano-Campos, O., Gómez-Velasco, D.V., et al.(2021). Increased visceral fat accumulation modifies the effect of insulin resistance on arterial stiffness and hypertension risk . Nutrition, Metabolism and Cardiovascular Diseases. 31. (2). p. 506-517.

Mehta, R., Martagon, A.J., Galan Ramirez, G.A., Antonio-Villa, N.E., Vargas-Vázquez, A., Elias-Lopez, D., Gonzalez-Retana, G., Rodríguez-Encinas, B., Ceballos-Macías, J.J., Romero-Zazueta, A., et al.(2021). Familial hypercholesterolemia in Mexico: Initial insights from the national registry . Journal of Clinical Lipidology. 15. (1). p. 124-133.

Bello-Chavolla, O.Y., Antonio-Villa, N.E., Vargas-Vázquez, A., Viveros-Ruiz, T.L., Almeda-Valdes, P., Gomez-Velasco, D., Mehta, R., Elias-López, D., Cruz-Bautista, I., Roldán-Valadez, E., et al.(2020). Metabolic Score for Visceral Fat (METS-VF), a novel estimator of intra-abdominal fat content and cardio-metabolic health . Clinical Nutrition. 39. (5). p. 1613-1621.

Gómez-Velasco, D.V., Almeda-Valdes, P., Martagón, A.J., Galán-Ramírez, G.A., Aguilar-Salinas, C.A.(2019). Empowerment of patients with type 2 diabetes: Current perspectives . Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12. p. 1311-1321.

Bello-Chavolla, O.Y., Antonio-Villa, N.E., Vargas-Vázquez, A., Martagón, A.J., Mehta, R., Arellano-Campos, O., Gómez-Velasco, D.V., Almeda-Valdés, P., Cruz-Bautista, I., Melgarejo-Hernandez, M.A., et al.(2019). Prediction of incident hypertension and arterial stiffness using the non–insulin-based metabolic score for insulin resistance (METS-IR) index . Journal of Clinical Hypertension. 21. (8). p. 1063-1070.

Almeda-Valdes, P., Velasco, D.V.G., Campos, O.A., Bello-Chavolla, O.Y., Sevilla-González, M.D.R., Ruiz, T.V., Rosado, A.J.M., Bautista, C.J., Hernandez, L.M., Cruz-Bautista, I., et al.(2019). The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-size adipocytes . European Journal of Endocrinology. 180. (2). p. 99-107.

Almeda-Valdes P, Gomez-Velasco D, Arellano-Campos O, Bello-Chavolla OY, Sevilla-González MDR, Viveros-Ruiz T, Martagón AJ, Bautista CJ, Aguilar-Salinas C(2018). The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-sized adipocytes . European journal of endocrinology.

EAS Familial Hypercholesterolaemia Studies Collaboration, EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) Investigators(2018). Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) . Atherosclerosis.

Mehta R, Martagon AJ, Galan Ramirez GA, Gonzalez Retana G, Martinez-Beltran M, Vargas Vazquez A, Vazquez-Cardenas A, Aguilar-Salinas CA(2018). The development of the Mexican Familial Hypercholesterolemia (FH) National Registry . Atherosclerosis.

(2018). Mexican Carriers of the HNF1A p.E508K Variant Do Not Experience an Enhanced Response to Sulfonylureas . Diabetes Care.

(2018). Identification of a threshold to discriminate fasting hypertriglyceridemia with postprandial values . Lipids in Health and Disease.

Bello-Chavolla OY, Almeda-Valdes P, Gomez-Velasco D, Viveros-Ruiz T, Cruz-Bautista I, Romo-Romo A, Sánchez-Lázaro D, Meza-Oviedo D, Vargas-Vázquez A, Aguilar-Salinas CA(2018). METS-IR, a novel score to evaluate insulin sensitivity, is predictive of visceral adiposity and incident type 2 diabetes . European journal of endocrinology.

Jan Antonio Lammel-Lindemann, Eduardo Flores-Villalba, Alexandro Jose Martagón, Eduardo DeObeso-Gonzalez, Francisco Puente-Gallegos(2018). Noncholestatic acute hepatocellular injury following candesartan administration . British Journal of Clinical Pharmacology. 84. (1). p. 204--207. Wiley

(2018). Noncholestatic acute hepatocellular injury following candesartan administration . British Journal of Clinical Pharmacology.

Lammel-Lindemann, J.A., Flores-Villalba, E., Martagón, A.J., DeObeso-Gonzalez, E., Puente-Gallegos, F.(2018). Noncholestatic acute hepatocellular injury following candesartan administration . British Journal of Clinical Pharmacology. 84. (1). p. 204-207.

Vallejo-Vaz, A.J., Marco, M.D., Stevens, C.A.T., Akram, A., Freiberger, T., Hovingh, G.K., Kastelein, J.J.P., Mata, P., Raal, F.J., Santos, R.D., et al.(2018). Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) . Atherosclerosis. 277. p. 234-255.

Sevilla-González, M.D.R., Aguilar-Salinas, C.A., Muñóz-Hernández, L., Almeda-Valdés, P., Mehta, R., Zubirán, R., Bello-Chavolla, O.Y., Gómez-Velasco, D.V., Vargas-Vázquez, A., Viveros-Ruíz, T., et al.(2018). Identification of a threshold to discriminate fasting hypertriglyceridemia with postprandial values . Lipids in Health and Disease. 17. (1).

Bello-Chavolla, O.Y., Almeda-Valdes, P., Gomez-Velasco, D., Viveros-Ruiz, T., Cruz-Bautista, I., Romo-Romo, A., Sánchez-Lázaro, D., Meza-Oviedo, D., Vargas-Vázquez, A., Campos, O.A., et al.(2018). METS-IR, a novel score to evaluate insulin sensitivity, is predictive of visceral adiposity and incident type 2 diabetes . European Journal of Endocrinology. 178. (5). p. 533-544.

Martagón, A.J., Bello-Chavolla, O.Y., Arellano-Campos, O., Almeda-Valdés, P., Walford, G.A., Cruz-Bautista, I., Gómez-Velasco, D.V., Mehta, R., Munoz-Hernandez, L., Sevilla-Gonzalez, M., et al.(2018). Mexican carriers of the HNF1A p. E508K variant do not experiencean enhanced response to sulfonylureas . Diabetes Care. 41. (8). p. 1726-1731.

Mehta, R., Martagon, A.J., Galan Ramirez, G.A., Gonzalez Retana, G., Martinez-Beltran, M., Vargas Vazquez, A., Vazquez-Cardenas, A., Aguilar-Salinas, C.A.(2018). The development of the Mexican Familial Hypercholesterolemia (FH) National Registry . Atherosclerosis. 277. p. 517-523.

(2016). The panorama of familial hypercholesterolemia in Latin America: a systematic review . Journal of Lipid Reserach.

Roopa Mehta, Rafael Zubirán, Alexandro J. Martagón, Alejandra Vazquez-Cárdenas, Yayoi Segura-Kato, María Teresa Tusié-Luna, Carlos A. Aguilar-Salinas(2016). The panorama of familial hypercholesterolemia in Latin America: a systematic review . Journal of Lipid Research. 57. (12). p. 2115--2129. American Society for Biochemistry {\&} Molecular Biology ({ASBMB})

Mehta, R., Zubirán, R., Martagón, A.J., Vazquez-Cárdenas, A., Segura-Kato, Y., Tusié-Luna, M.T., Aguilar-Salinas, C.A.(2016). The panorama of familial hypercholesterolemia in Latin America: A systematic review . Journal of Lipid Research. 57. (12). p. 2115-2129.

Lin, J.Z., Martagón, A.J., Cimini, S.L., Gonzalez, D.D., Tinkey, D.W., Biter, A., Baxter, J.D., Webb, P., Gustafsson, J.-Å., Hartig, S.M., et al.(2015). Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat . Cell Reports. 13. (8). p. 1528-1537.

Martagón, A.J., Lin, J.Z., Cimini, S.L., Webb, P., Phillips, K.J.(2015). The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice . PLoS ONE. 10. (4).

Martagón, A.J., Philips, K.J., Webb, P.(2013). Opening the black box: Revealing the molecular basis of thyroid hormone transport . Endocrinology. 154. (7). p. 2266-2269.

Lin, J.Z., Martagón, A.J., Hsueh, W.A., Baxter, J.D., Gustafsson, J.-Å., Webb, P., Phillips, K.J.(2012). Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor . Endocrinology. 153. (12). p. 6136-6144.

Shea, P.R., Ewbank, A.L., Gonzalez-Lugo, J.H., Martagon-Rosado, A.J., Martinez-Gutierrez, J.C., Rehman, H.A., Serrano-Gonzalez, M., Fittipaldi, N., Beres, S.B., Flores, A.R., et al.(2011). Group a streptococcus emm gene types in pharyngeal isolates, Ontario, Canada, 2002-2010 . Emerging Infectious Diseases. 17. (11). p. 2010-2017.

Shea, P.R., Beres, S.B., Flores, A.R., Ewbank, A.L., Gonzalez-Lugo, J.H., Martagon-Rosado, A.J., Martinez-Gutierrez, J.C., Rehman, H.A., Serrano-Gonzalez, M., Fittipaldi, N., et al.(2011). Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations . Proceedings of the National Academy of Sciences of the United States of America. 108. (12). p. 5039-5044.

PREPRINT

Magdalena Del Rocio Sevilla-Gonzalez, Brigette Bourguet-Ramirez, Laura Sofia Lazaro-Carrera, Alexandro J Martagon-Rosado, Donaji Veronica Gomez-Velasco, Tannia Leticia Viveros-Ruiz(2020). Evaluation of a Web Platform to Record Lifestyle Habits in Subjects at Risk of Developing Type 2 Diabetes in a Middle-Income Population: Prospective Interventional Study (Preprint) . {JMIR} Publications Inc.