Profile Details

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Hire Dr. Vitalina Bashinskaya

Ukraine

USD 25 /hr

PhD | Head of Sequencing direction at Diagen genetic laboratory | Complex disease genetics, NGS

Profile Summary

PhD (Molecular Biology), Researcher in complex disease genetics, Head of Sequencing direction at Diagen genetic laboratory. h-index 5 (Google Scholar) Main ongoing and completed projects: • Genetics of substance use disorders (leading) • Establishment of workflows on Illumina MiSeq system for different applications (leading) • Establishment and optimization of workflow on the Qiagen Genereader sequencer for targeted sequencing of FFPE tumour samples for clinical research applications (co-leading) • Genetics of multiple sclerosis (MS): susceptibility, clinical heterogeneity, pharmacogenetics (main investigator) • Genetics of myocardial infarction and ischaemic stroke (co-investigator) • Analysis of microRNA expression levels in plasma of myocardial infarction patients and healthy volunteers (co-investigator) • Construction of single-locus SNP and CNV genotyping assays I am a wet-lab biologist with some data analysis and bioinformatic skills, which I constantly tend to improve. My research expertise is in the area of complex disease genomics, with particular focus on autoimmune and psychiatric disorders. I have some experience in NGS (Qiagen, Illumina) both in wet-lab and analysis (quality control and variant annotation). My computational skills include mainly R, shell scripting, use of APSampler, GraphPad, Quanto, EAGLE, Haploview, tools for variant annotation, search for protein-protein interactions, miRNA-target interactions, GO analysis, NGS analysis. I have an inter-disciplinary career and educational background (I graduated from a biomedical faculty and throughout my career combined wet-lab and computational work). On top of that, I am quite strong in literature analysis and scientific writing, and can translate texts in/from Russian/Ukrainian.

Subject Matter Expertise

• ★ Genetics & Genomics
• ★ Biostatistics
• ☆ Data Processing
• ☆ Molecular Biology
• ☆ Health & Medicine (General)
• ☆ Pharmacogenomics
• ☆ Substance Abuse & Addiction
• ☆ Immunogenetics
• ☆ Multiple Sclerosis
• ☆ Multivariate Analysis
• ☆ Next Generation Sequencing

Services

• Scientific consulting
• Data Science
• Secondary Research
• Statistical review
• Editing

Scientific consulting Short-term consulting

Data Science Analytical report, Analysis from dataset, Quantitative analysis

Editing Language editing, Translation

Statistical review Conduct simple analysis, Recommend suitable tests

Secondary Research Literature search, Find latest research, Prepare evidence-based answers, Prepare a research report, Summarize findings

Work Experience

• Head of Sequencing Direction

  Diagen genetic laboratory

  August 2020 - Present

• Researcher

  Diagen genetic laboratory

  January 2018 - Present

• Researcher

  Pirogov Russian National Research Medical University

  2016 - December 2017

• Researcher

  Russian Cardiology Research and Production Complex

  September 2015 - December 2017

• Junior researcher

  Pirogov Russian National Research Medical University

  2014 - 2016

• Junior researcher

  Russian Cardiology Research and Production Complex

  2014 - August 2015

• Laboratory assistant

  Russian Cardiology Research and Production Complex

  2010 - 2014

Education

• PhD (Molecular biology and medical biotechnology)

  Pirogov Russian National Research Medical University

  September 2012 - December 2016

• Specialist diploma (Molecular biology and medical biotechnology)

  Pirogov Russian National Research Medical University

  September 2006 - June 2012

Publications

JOURNAL ARTICLE
• (2019). Genetic differences between primary progressive and relapsing-remitting multiple sclerosis: The impact of immune-related genes variability . Multiple Sclerosis and Related Disorders.
• Osmak GJ, Titov BV, Matveeva NA, Bashinskaya VV, Shakhnovich RM, Sukhinina TS, Kukava NG, Ruda MY, Favorova OO(2018). Impact of 9p21.3 region and atherosclerosis-related genes' variants on long-term recurrent hard cardiac events after a myocardial infarction . Gene.
• Kulakova O, Bashinskaya V, Kiselev I, Baulina N, Tsareva E, Nikolaev R, Kozin M, Shchur S, Favorov A, Boyko A, et al.(2017). Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis: the impact of genome-wide association studies identified disease risk loci . Pharmacogenomics.
• Popova EV, Kiselev IS, Boyko AN, Sivertseva SA, Malkova NA, Korobko DS, Spirin NN, Kasatkin DS, Karaeva AV, Turova EL, et al.(2017). [Polymorphic variants of the immune response genes as risk factors for primary progressive multiple sclerosis] . Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.
• Kulakova OG, Bashinskaya VV, Tsareva EY, Boyko AN, Favorova OO, Gusev EI(2016). [Association analysis of cytokine receptors' genes polymorphisms with clinical features of multiple sclerosis] . Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.
• Bashinskaya VV, Kulakova OG, Boyko AN, Favorov AV, Favorova OO(2015). A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches . Human genetics.
• Kiselev I, Bashinskaya V, Kulakova O, Baulina N, Popova E, Boyko A, Favorova O(2015). Variants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity . International journal of molecular sciences.
• Bashinskaya VV, Kulakova OG, Kiselev IS, Baulina NM, Favorov AV, Boyko AN, Tsareva EY, Favorova OO(2015). GWAS-identified multiple sclerosis risk loci involved in immune response: validation in Russians . Journal of neuroimmunology.