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USD 150 /hr

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Hire Tharindunee J.

Sri Lanka

USD 150 /hr

Biochemist with 10 years of experience in G-protein coupled receptor pharmacology and drug discovery

Profile Summary

I received my PhD from the Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore. My post-graduate research at NUS included developing selective stapled peptide drugs to target G-protein coupled receptors (GPCRs) in the CNS and in vitro assay development. Currently, I work as a lecturer in biochemistry and molecular biology at the Department of Chemistry, University of Colombo. My research group is interested in developing biased agonists of GPCRs using in silico drug development tools and in vitro signaling assays using mammalian cell cultures and determining the structural and functional features of GPCRs that result in selective activation of signaling pathways.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Structural Biology
• ☆ Binding Assays
• ☆ PCR
• ☆ Recombinant DNA
• ☆ Plasmid DNA
• ☆ Kinases
• ☆ Neurochemistry
• ☆ Neuropharmacology
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Biomarker Discovery
• ☆ Blotting
• ☆ Immunohistochemistry

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Product Development Product Evaluation, Product Validation, Concept Development

Work Experience

Lecturer

University of Colombo

October 2020 - Present

Visiting Lecturer

University of Colombo, Sri Lanka

February 2019 - October 2020

teaching assistant/ research assistant/ instructor

University of Colombo, Sri Lanka

January 2012 - July 2012

Education

PhD (Pharmacology, Yong Loo Lin School of Medicine)

National University of Singapore

July 2013 - December 2017

Bachelor in Science (Biochemistry and Molecular Biology)

University of Colombo, Sri Lanka

August 2008 - December 2012

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Kumar, J.R., Rajkumar, R., Jayakody, T., Marwari, S., Hong, J.M., Ma, S., Gundlach, A.L., Lai, M.K.P., Dawe, G.S.(2017). Relaxin’ the brain: a case for targeting the nucleus incertus network and relaxin-3/RXFP3 system in neuropsychiatric disorders . British Journal of Pharmacology. 174. (10). p. 1061-1076.

Jayakody, T., Marwari, S., Lakshminarayanan, R., Tan, F.C.K., Johannes, C.W., Dymock, B.W., Poulsen, A., Herr, D.R., Dawe, G.S.(2016). Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity . Peptides. 84. p. 44-57.