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Hire Dr. Tameryn S.

South Africa

USD 20 /hr

Scientific researcher with expertise in academic writing, editing and analysis.

Profile Summary

I am a scientist with research experience in medicinal chemistry. I have worked on the development of organometallic and coordination compounds as potential anti-parasitics and anti-cancer agents. I have experience in the field of parasitology, specifically with respect to the malaria parasite.

Subject Matter Expertise

• ☆ Chemistry
• ☆ Coordination Compounds
• ☆ Inorganic Chemistry
• ☆ Medicinal Chemistry
• ☆ Malaria
• ☆ Research
• ☆ Technical & Scientific Writing

Services

• Services details not provided.

Work Experience

Teaching and Research Fellow

University of Leeds

May 2020 - Present

International Grants Coordinator

University of Cape Town

May 2019 - February 2020

Postdoctoral Research fellow

Lund University

October 2017 - August 2018

Postdoctoral research fellow

University of Cape Town Faculty of Science

April 2014 - September 2017

Education

Ph.D. in chemistry

University of Cape Town

February 2011 - February 2014

M.Sc. in chemistry

University of Cape Town

February 2009 - December 2010

B.Sc.(hons) in chemistry

University of Cape Town

January 2008 - December 2008

B.Sc.

University of Cape Town

January 2004 - December 2007

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2019). Structure-activity relationship studies of antiplasmodial cyclometallated ruthenium(II), rhodium(III) and iridium(III) complexes of 2-phenylbenzimidazoles . European Journal of Medicinal Chemistry. 161. p. 11-21.

Baartzes, N., Stringer, T., Seldon, R., Warner, D.F., Taylor, D., Wittlin, S., Chibale, K., Smith, G.S.(2019). Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: Antimicrobial evaluation and mechanistic insights . European Journal of Medicinal Chemistry. 180. p. 121-133.

Stringer, T., Quintero, M.A.S., Wiesner, L., Smith, G.S., Nordlander, E.(2019). Evaluation of PTA-derived ruthenium(II) and iridium(III) quinoline complexes against chloroquine-sensitive and resistant strains of the Plasmodium falciparum malaria parasite . Journal of Inorganic Biochemistry. 191. p. 164-173.

Stringer T(2019). Antiprotozoal activity of palladium(II) salicylaldiminato thiosemicarbazone complexes on metronidazole resistant Trichomonas vaginalis . Inorganic Chemistry Communications. 102. p. 1-4.

Stringer, T., Wiesner, L., Smith, G.S.(2019). Ferroquine-derived polyamines that target resistant Plasmodium falciparum . European Journal of Medicinal Chemistry. 179. p. 78-83.

Chellan, P., Stringer, T., Shokar, A., Au, A., Tam, C., Cheng, L.W., Smith, G.S., Land, K.M.(2019). Antiprotozoal activity of palladium(II) salicylaldiminato thiosemicarbazone complexes on metronidazole resistant Trichomonas vaginalis . Inorganic Chemistry Communications. 102. p. 1-4.

Stringer T(2019). Antiplasmodial activity and in vivo bio-distribution of chloroquine molecules released with a 4-(4-ethynylphenyl)-triazole moiety from organometallo-cobalamins . Molecules. 24.

Stringer T(2019). Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: Antimicrobial evaluation and mechanistic insights . European Journal of Medicinal Chemistry. 180. p. 121-133.

Rylands, L.-I., Welsh, A., Maepa, K., Stringer, T., Taylor, D., Chibale, K., Smith, G.S., Rylands, L.-I., Welsh, A., Maepa, K., et al.(2019). Structure-activity relationship studies of antiplasmodial cyclometallated ruthenium(II), rhodium(III) and iridium(III) complexes of 2-phenylbenzimidazoles . European Journal of Medicinal Chemistry. 161. p. 11-21.

Rossier, J., Sovari, S.N., Pavic, A., Vojnovic, S., Stringer, T., Bättig, S., Smith, G.S., Nikodinovic-Runic, J., Zobi, F.(2019). Antiplasmodial activity and in vivo bio-distribution of chloroquine molecules released with a 4-(4-ethynylphenyl)-triazole moiety from organometallo-cobalamins . Molecules. 24. (12).

Tameryn Stringer, Diana R. Melis, Gregory S. Smith (2019). N,O-Chelating quinoline-based half-sandwich organorhodium and -iridium complexes: synthesis, antiplasmodial activity and preliminary evaluation as transfer hydrogenation catalysts for the reduction of NAD+ . Dalton Transactions.

Rylands LI, Welsh A, Maepa K, Stringer T, Taylor D, Chibale K, Smith GS.(2019). Structure-activity relationship studies of antiplasmodial cyclometallated ruthenium(II), rhodium(III) and iridium(III) complexes of 2-phenylbenzimidazoles. European Journal of Medicinal Chemistry. 161.

Stringer T, Stringer T(2019). Ferroquine-derived polyamines that target resistant Plasmodium falciparum . European Journal of Medicinal Chemistry. 179. p. 78-83.

Stringer T., Melis DR., Smith GS.(2019). N,O-Chelating quinoline-based half-sandwich organorhodium and -iridium complexes: synthesis, antiplasmodial activity and preliminary evaluation as transfer hydrogenation catalysts for the reduction of NAD+ . Dalton Transactions. 48. p. 13143-13148.

Cassells, I., Stringer, T., Hutton, A.T., Prince, S., Smith, G.S.(2018). Impact of various lipophilic substituents on ruthenium(II), rhodium(III) and iridium(III) salicylaldimine-based complexes: synthesis, in vitro cytotoxicity studies and DNA interactions . Journal of Biological Inorganic Chemistry. 23. (5). p. 763-774.

Stringer, T., Seldon, R., Liu, N., Warner, D.F., Tam, C., Cheng, L.W., Land, K.M., Smith, P.J., Chibale, K., Smith, G.S.(2017). Antimicrobial activity of organometallic isonicotinyl and pyrazinyl ferrocenyl-derived complexes . Dalton Transactions. 46. (30). p. 9875-9885.

Baartzes, N., Stringer, T., Chellan, P., Combrinck, J.M., Smith, P.J., Hutton, A.T., Smith, G.S.(2016). Synthesis, characterization, antiplasmodial evaluation and electrochemical studies of water-soluble heterobimetallic ferrocenyl complexes . Inorganica Chimica Acta. 446. p. 111-115.

Stringer, T., De Kock, C., Guzgay, H., Okombo, J., Liu, J., Kanetake, S., Kim, J., Tam, C., Cheng, L.W., Smith, P.J., et al.(2016). Mono- and multimeric ferrocene congeners of quinoline-based polyamines as potential antiparasitics . Dalton Transactions. 45. (34). p. 13415-13426.

Baartzes, N., Stringer, T., Okombo, J., Seldon, R., Warner, D.F., de Kock, C., Smith, P.J., Smith, G.S.(2016). Mono- and polynuclear ferrocenylthiosemicarbazones: Synthesis, characterisation and antimicrobial evaluation . Journal of Organometallic Chemistry. 819. p. 166-172.

Baartzes, N., Stringer, T., Seldon, R., Warner, D.F., De Kock, C., Smith, P.J., Smith, G.S.(2016). Synthesis, characterization and antimicrobial evaluation of mono- and polynuclear ferrocenyl-derived amino and imino complexes . Journal of Organometallic Chemistry. 809. p. 79-85.

Adams, M., Stringer, T., De Kock, C., Smith, P.J., Land, K.M., Liu, N., Tam, C., Cheng, L.W., Njoroge, M., Chibale, K., et al.(2016). Bioisosteric ferrocenyl-containing quinolines with antiplasmodial and antitrichomonal properties . Dalton Transactions. 45. (47). p. 19086-19095.

(2015). Antimalarial activity of ruthenium(ii) and osmium(ii) arene complexes with mono- and bidentate chloroquine analogue ligands . Dalton Transactions. 44. (44). p. 19314-19329.

Stringer, T., Guzgay, H., Combrinck, J.M., Hopper, M., Hendricks, D.T., Smith, P.J., Land, K.M., Egan, T.J., Smith, G.S.(2015). Synthesis, characterization and pharmacological evaluation of ferrocenyl azines and their rhodium(I) complexes . Journal of Organometallic Chemistry. 788. p. 1-8.

(2015). Improved antiparasitic activity by incorporation of organosilane entities into half-sandwich ruthenium(II) and rhodium(III) thiosemicarbazone complexes . Dalton Transactions. 44. (5). p. 2456-2468.

Stringer, T., Taylor, D., Guzgay, H., Shokar, A., Au, A., Smith, P.J., Hendricks, D.T., Land, K.M., Egan, T.J., Smith, G.S.(2015). Polyamine quinoline rhodium complexes: Synthesis and pharmacological evaluation as antiparasitic agents against Plasmodium falciparum and Trichomonas vaginalis . Dalton Transactions. 44. (33). p. 14906-14917.

Stringer Tameryn, Nkoana Winnie, Nyoni Dubekile, Chellan Prinessa, Taylor Dale, Smith Peter J., Hutton Alan T., Smith Gregory S.(2014). Heterometallic half-sandwich complexes containing a ferrocenyl motif: Synthesis, molecular structure, electrochemistry and antiplasmodial evaluation . Journal of Organometallic Chemistry. 752. p. 67-75.

Nkoana, W., Nyoni, D., Chellan, P., Stringer, T., Taylor, D., Smith, P.J., Hutton, A.T., Smith, G.S.(2014). Heterometallic half-sandwich complexes containing a ferrocenyl motif: Synthesis, molecular structure, electrochemistry and antiplasmodial evaluation . Journal of Organometallic Chemistry. 752. p. 67-75.

Stringer Tameryn, Taylor Dale, de Kock Carmen, Guzgay Hajira, Au Aaron, An Seung Hwan, Sanchez Benjamin, O'Connor Raquel, Patel Neal, Land Kirkwood M., et al.(2013). Synthesis, characterization, antiparasitic and cytotoxic evaluation of thioureas conjugated to polyamine scaffolds . European Journal of Medicinal Chemistry. 69. p. 90-98.

Stringer, T., Taylor, D., De Kock, C., Guzgay, H., Au, A., An, S.H., Sanchez, B., O'Connor, R., Patel, N., Land, K.M., et al.(2013). Synthesis, characterization, antiparasitic and cytotoxic evaluation of thioureas conjugated to polyamine scaffolds . European Journal of Medicinal Chemistry. 69. p. 90-98.

Stringer Tameryn, Hendricks Denver T., Guzgay Hajira, Smith Gregory S.(2012). Synthesis and characterization of multimeric salicylaldimine thiosemicarbazones and their Pd(II) and Pt(II) complexes . Polyhedron. 31. p. 486-493.

Stringer, T., Hendricks, D.T., Guzgay, H., Smith, G.S.(2012). Synthesis and characterization of multimeric salicylaldimine thiosemicarbazones and their Pd(II) and Pt(II) complexes . Polyhedron. 31. (1). p. 486-493.

Stringer Tameryn, Chellan Prinessa, Shokar Ajit, Dornbush Padraick J., Vazquez-Anaya Guillermo, Land Kirkwood M., Chibale Kelly, Smith Gregory S.(2011). Synthesis and in vitro evaluation of palladium(II) salicylaldiminato thiosemicarbazone complexes against Trichomonas vaginalis . Journal of Inorganic Biochemistry. 105. p. 1562-1568.

(2011). Mono- and dinuclear (eta(6)-arene) ruthenium(II) benzaldehyde thiosemicarbazone complexes: Synthesis, characterization and cytotoxicity . Inorganic Chemistry Communications. 14. p. 956-960.

Chellan, P., Stringer, T., Shokar, A., Dornbush, P.J., Vazquez-Anaya, G., Land, K.M., Chibale, K., Smith, G.S.(2011). Synthesis and in vitro evaluation of palladium(II) salicylaldiminato thiosemicarbazone complexes against Trichomonas vaginalis . Journal of Inorganic Biochemistry. 105. (12). p. 1562-1568.

Stringer, T., Therrien, B., Hendricks, D.T., Guzgay, H., Smith, G.S.(2011). Mono- and dinuclear (η ⁶ -arene) ruthenium(II) benzaldehyde thiosemicarbazone complexes: Synthesis, characterization and cytotoxicity . Inorganic Chemistry Communications. 14. (6). p. 956-960.

Stringer Tameryn, Chellan Prinessa, Therrien Bruno, Shunmoogam-Gounden Nelusha, Hendricks Denver T., Smith Gregory S.(2009). Synthesis and structural characterization of binuclear palladium(II) complexes of salicylaldimine dithiosemicarbazones . Polyhedron. 28. p. 2839-2846.

Stringer, T., Chellan, P., Therrien, B., Stringer, T., Chellan, P., Stringer, T., Chellan, P., Therrien, B., Shunmoogam-Gounden, N., Hendricks, D.T., et al.(2009). Synthesis and structural characterization of binuclear palladium(II) complexes of salicylaldimine dithiosemicarbazones . Polyhedron. 28. (14). p. 2839-2846.

BOOK CHAPTER

Stringer, Baartzes, N, T, Smith, G.S.(2019). Targeting Sensitive-Strain and Resistant-Strain Malaria Parasites Through a Metal-Based Approach .

Stringer T., Baartzes N., Smith GS.(2019). Targeting Sensitive-Strain and Resistant-Strain Malaria Parasites Through a Metal-Based Approach.