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Hire Srinivas N.

United States

USD 30 /hr

Bioinformatician | Computational Biologist | Data Analyst | R programmer | Statistician | Scientific writer

Profile Summary

• Development and implementation of novel pipelines and software for better understanding of genomic/transcriptomic data generated by next-generation sequencing (NGS) techniques. • Statistical programming using R. R shiny web applications for pipeline automation to streamline analyses for biologists as well as Website development using R shiny dashboard. • Analyze and interpret gene expression data by performing differential expression analysis. Data maintenance, clean-up and organization using SQL. • Experience in handling DNA/RNA sequencing data, reporting copy-number alterations, identifying somatic mutations and document them to make meaningful and understandable figures and tables for scientific publications. • Implementing Machine-Learning prediction algorithms using logistic regression models, Random Forest Classifiers, Support Vector Machines and XGBoost. • Expertise in Cancer biology, Immunology, Molecular biology and Genetics. • Manuscript preparation, analysis/figures/methodology documentation for high quality journals including poster presentation for scientific conferences.

Subject Matter Expertise

• ★ Bioinformatics
• ★ Phylogenetics

Services

• Writing
• Data & AI

Writing Technical Writing

Data & AI Statistical Analysis, Algorithm Design-Non ML, Data Visualization

Work Experience

Bioinformatician/Computational Biologist

University of Michigan, Ann Arbor

December 2017 - Present

BIoinformatician

Indiana University School of Medicine

May 2015 - November 2017

Education

Master of Science in Bioinformatics

Indiana University - Purdue University Indianapolis

January 2015 - December 2016

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Zaslavsky AB, Adams MP, Cao X, Maj T, Choi JE, Stangl-Kremser J, Patel S, Putelo A, Lee SK, Nallandhighal S, et al.(2020). Platelet PD-L1 suppresses anti-cancer immune cell activity in PD-L1 negative tumors . Scientific reports.

Salami SS, Tosoian JJ, Nallandhighal S, Jones TA, Brockman S, Elkhoury FF, Bazzi S, Plouffe KR, Siddiqui J, Liu CJ, et al.(2020). Serial Molecular Profiling of Low-grade Prostate Cancer to Assess Tumor Upgrading: A Longitudinal Cohort Study . European urology.

Nallandhighal S, Tran TM(2019). Reply to Liu et al . The Journal of infectious diseases.

Salami SS, Kaplan JB, Nallandhighal S, Takhar M, Tosoian JJ, Lee M, Yoon J, Hovelson DH, Plouffe KR, Kaffenberger SD, et al.(2019). Biologic Significance of Magnetic Resonance Imaging Invisibility in Localized Prostate Cancer . JCO precision oncology.

Nallandhighal S, Park GS, Ho YY, Opoka RO, John CC, Tran TM(2019). Whole-Blood Transcriptional Signatures Composed of Erythropoietic and NRF2-Regulated Genes Differ Between Cerebral Malaria and Severe Malarial Anemia . The Journal of infectious diseases.

Nallandhighal S, Park G, Ho Y, Opoka R, John C, Tran T(2018). 963. Whole Blood Transcriptome Analysis Reveals Differences in Erythropoiesis and Neurologically Relevant Pathways Between Cerebral Malaria and Severe Malarial Anemia . Open forum infectious diseases.

Clemente TM, Mulye M, Justis AV, Nallandhighal S, Tran TM, Gilk SD(2018). Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages . Infection and immunity.

PREPRINT

Clemente TM, Mulye M, Justis AV, Nallandhighal S, Tran TM, Gilk SD(2018). Coxiella burnetiiblocks intracellular IL-17 signaling in macrophages .