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Hire Dr. Sarah M.

Canada

Profile Summary

Results-driven immunologist with clinical and pre-clinical research experience in vaccine development and infectious disease, COPD, asthma and autoimmunity. Highly personable, with the ability to effectively lead teams to increase productivity and meet project deliverables. Demonstrated ability to simplify complex scientific and medical concepts and effectively disseminate information through writing and presentations. High level of productivity with more than 25 scientific articles, extensive experience in scientific communication and securing research funding.

Subject Matter Expertise

• ☆ Vaccine Development
• ☆ Infectious Disease
• ☆ Medical Sciences
• ☆ Asthma
• ☆ PreMarket Approval (PMA) Applications
• ☆ Medical Writing
• ☆ Technical & Scientific Writing

Services

• Writing
• Consulting
• Product Development

Work Experience

Post Doctoral Fellow

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

April 2016 - Present

Post Doctoral Fellow

Johns Hopkins Medicine

October 2013 - April 2016

Post Doctoral Fellow

Johns Hopkins University Bloomberg School of Public Health

August 2011 - October 2013

Education

PhD (Pathology and Molecular Medicine)

McMaster University

September 2004 - July 2011

B.MSc

University of Western Ontario Faculty of Science

September 1999 - April 2004

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

McCormick, S.M., Heller, N.M.(2015). Commentary: IL-4 and IL-13 receptors and signaling . Cytokine. 75. (1). p. 38-50.

Sussan, T.E., Gajghate, S., Chatterjee, S., Mandke, P., McCormick, S., Sudini, K., Kumar, S., Breysse, P.N., Diette, G.B., Sidhaye, V.K., et al.(2015). Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function . American Journal of Physiology - Lung Cellular and Molecular Physiology. 309. (1). p. L27-L36.

McCormick, S.M., Heller, N.M.(2015). Regulation of macrophage, dendritic cell, and microglial phenotype and function by the SOCS proteins . Frontiers in Immunology. 6. (OCT).

Jeyanathan, M., McCormick, S., Lai, R., Afkhami, S., RShaler, C., Horvath, C.N., Damjanovic, D., Zganiacz, A., Barra, N., Ashkar, A., et al.(2014). Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigenpresenting cells . Mucosal Immunology. 7. (3). p. 670-683.

Sussan, T.E., Ingole, V., Kim, J.-H., McCormick, S., Negherbon, J., Fallica, J., Akulian, J., Yarmus, L., Feller-Kopman, D., Wills-Karp, M., et al.(2014). Source of biomass cooking fuel determines pulmonary response to household air pollution . American Journal of Respiratory Cell and Molecular Biology. 50. (3). p. 538-548.

Shaler, C.R., Horvath, C.N., McCormick, S., Jeyanathan, M., Khera, A., Zganiacz, A., Kasinska, J., Stampfli, M.R., Xing, Z.(2013). Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis . PLoS ONE. 8. (3).

Damjanovic, D., Small, C.-L., Jeyanathan, M., McCormick, S., Xing, Z.(2013). Corrigendum to "Immunopathology in influenza virus infection: Uncoupling the friend from foe" [Clin. Immunol. 144 (2012) 57-69] . Clinical Immunology. 146. (1).

Damjanovic, D., Small, C.-L., Jeyananthan, M., McCormick, S., Xing, Z.(2012). Immunopathology in influenza virus infection: Uncoupling the friend from foe . Clinical Immunology. 144. (1). p. 57-69.

McCormick, S., Shaler, C.R., Small, C.-L., Horvath, C., Damjanovic, D., Brown, E.G., Aoki, N., Takai, T., Xing, Z.(2011). Control of pathogenic CD4 T cells and lethal immunopathology by signaling immunoadaptor DAP12 during influenza infection . Journal of Immunology. 187. (8). p. 4280-4292.

Shaler, C.R., Kugathasan, K., McCormick, S., Damjanovic, D., Horvath, C., Small, C.-L., Jeyanathan, M., Chen, X., Yang, P.-C., Xing, Z.(2011). Pulmonary mycobacterial granuloma: Increased IL-10 production contributes to establishing a symbiotic host-microbe microenvironment . American Journal of Pathology. 178. (4). p. 1622-1634.

McCormick, S., Shaler, C.R., Xing, Z.(2011). Pulmonary mucosal dendritic cells in T-cell activation: Implications for TB therapy . Expert Review of Respiratory Medicine. 5. (1). p. 75-85.

Jeyanathan, M., Mu, J., McCormick, S., Damjanovic, D., Small, C.-L., Shaler, C.R., Kugathasan, K., Xing, Z.(2010). Murine airway luminal antituberculosis memory CD8 T cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment . American Journal of Respiratory and Critical Care Medicine. 181. (8). p. 862-872.

Small, C.-L., Shaler, C.R., McCormick, S., Jeyanathan, M., Damjanovic, D., Brown, E.G., Arck, P., Jordana, M., Kaushic, C., Ashkar, A.A., et al.(2010). Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung . Journal of Immunology. 184. (4). p. 2048-2056.

Mu, J., Jeyanathan, M., Shaler, C.R., Horvath, C., Damjanovic, D., Zganiacz, A., Kugathasan, K., McCormick, S., Xing, Z.(2010). Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell-independent protective immunity . Journal of Gene Medicine. 12. (8). p. 693-704.

Takenaka, S., McCormick, S., Safroneeva, E., Xing, Z., Gauldie, J.(2009). Influence of the tissue microenvironment on toll-like receptor expression by CD11c+ antigen-presenting cells isolated from mucosal tissues . Clinical and Vaccine Immunology. 16. (11). p. 1615-1623.

Small, C.-L., Mccormick, S., Gill, N., Kugathasan, K., Santosuosso, M., Donaldson, N., Heinrichs, D.E., Ashkar, A., Xing, Z.(2008). NK cells play a critical protective role in host defense against acute extracellular staphylococcus aureus bacterial infection in the lung . Journal of Immunology. 180. (8). p. 5558-5568.

McCormick, S., Santosuosso, M., Small, C.-L., Shaler, C.R., Zhang, X., Jeyanathan, M., Mu, J., Takenaka, S., Ngai, P., Gauldie, J., et al.(2008). Mucosally delivered dendritic cells activate T cells independently of IL-12 and endogenous APCs . Journal of Immunology. 181. (4). p. 2356-2367.

Kugathasan, K., Roediger, E.K., Small, C.-L., McCormick, S., Yang, P., Xing, Z.(2008). CD11c+ antigen presenting cells from the alveolar space, lung parenchyma and spleen differ in their phenotype and capabilities to activate naïve and antigen-primed T cells . BMC Immunology. 9.

Santosuosso, M., McCormick, S., Roediger, E., Zhang, X., Zganiacz, A., Lichty, B.D., Xing, Z.(2007). Mucosal luminal manipulation of T cell geography switches on protective efficacy by otherwise ineffective parenteral genetic immunization . Journal of Immunology. 178. (4). p. 2387-2395.

Divangahi, M., Yang, T., Kugathasan, K., McCormick, S., Takenaka, S., Gaschler, G., Ashkar, A., Stampfli, M., Gauldie, J., Bramson, J., et al.(2007). Critical negative regulation of type 1 T cell immunity and immunopathology by signaling adaptor DAP12 during intracellular infection . Journal of Immunology. 179. (6). p. 4015-4026.

Ngai, P., McCormick, S., Small, C., Zhang, X., Zganiacz, A., Aoki, N., Xing, Z.(2007). Gamma interferon responses of CD4 and CD8 T-cell subsets are quantitatively different and independent of each other during pulmonary Mycobacterium bovis BCG infection . Infection and Immunity. 75. (5). p. 2244-2252.

Malowany, J.I., McCormick, S., Santosuosso, M., Zhang, X., Aoki, N., Ngai, P., Wang, J., Leitch, J., Bramson, J., Wan, Y., et al.(2006). Development of cell-based tuberculosis vaccines: Genetically modified dendritic cell vaccine is a much more potent activator of CD4 and CD8 T cells than peptide- or protein-loaded counterparts . Molecular Therapy. 13. (4). p. 766-775.

Santosuosso, M., McCormick, S., Zhang, X., Zganiacz, A., Xing, Z.(2006). Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis . Infection and Immunity. 74. (8). p. 4634-4643.

McCormick, S., Santosuosso, M., Zhang, X.Z., Xing, Z.(2006). Manipulation of dendritic cells for host defence against intracellular infections . Biochemical Society Transactions. 34. (2). p. 283-286.

Santosuosso, M., McCormick, S., Xing, Z.(2005). Adenoviral vectors for mucosal vaccination against infectious diseases . Viral Immunology. 18. (2). p. 283-291.

Xing, Z., Santosuosso, M., McCormick, S., Yang, T.-C., Millar, J., Hitt, M., Wan, Y., Bramson, J., Vordermeier, H.M.(2005). Recent advances in the development of adenovirus- and poxvirus-vectored tuberculosis vaccines . Current Gene Therapy. 5. (5). p. 485-492.

Santosuosso, M., Zhang, X., McCormick, S., Wang, J., Hitt, M., Xing, Z.(2005). Mechanisms of mucosal and parenteral tuberculosis vaccinations: Adenoviral-based mucosal immunization preferentially elicits sustained accumulation of immune protective CD4 and CD8 T cells within the airway lumen . Journal of Immunology. 174. (12). p. 7986-7994.