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Profile Details
Contact
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☆☆☆☆☆
Hire Dr. Pieter Bos
United States
Profile Summary
Subject Matter Expertise
Services
Work Experience

Senior Scientist II

Schrodinger LLC New York Office

April 2018 - Present

Associate Research Scientist

Columbia University

September 2016 - February 2018

Postdoctoral Research Scientist

Columbia University

September 2014 - August 2016

Postdoctoral Research Scientist

Boston University

March 2012 - August 2014

Education

PhD Chemistry (Chemistry)

Rijksuniversiteit Groningen

September 2007 - March 2012

MSc Chemistry (Chemistry)

Rijksuniversiteit Groningen

September 2004 - June 2007

BSc Chemistry (Chemistry)

Rijksuniversiteit Groningen

September 2001 - June 2004

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
Bos, P.H., Lowry, E.R., Costa, J., Thams, S., Garcia-Diaz, A., Zask, A., Wichterle, H., Stockwell, B.R.(2019). Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents . Cell Chemical Biology. 26. (12). p. 1703-1715.e37.
Feng, H., Zhang, Y., Bos, P.H., Chambers, J.M., Dupont, M.M., Stockwell, B.R.(2019). K-Ras<sup>G12D</sup> Has a Potential Allosteric Small Molecule Binding Site . Biochemistry. 58. (21). p. 2542-2554.
Shimada, K., Reznik, E., Stokes, M.E., Krishnamoorthy, L., Bos, P.H., Song, Y., Quartararo, C.E., Pagano, N.C., Carpizo, D.R., deCarvalho, A.C., et al.(2018). Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells . Cell Chemical Biology. 25. (5). p. 585-594.e7.
Gaschler, M.M., Andia, A.A., Liu, H., Csuka, J.M., Hurlocker, B., Vaiana, C.A., Heindel, D.W., Zuckerman, D.S., Bos, P.H., Reznik, E., et al.(2018). FINO<inf>2</inf> initiates ferroptosis through GPX4 inactivation and iron oxidation . Nature Chemical Biology. 14. (5). p. 507-515.
Stork, G., Yamashita, A., Hanson, R.M., Phan, L., Phillips, E., Dub&#233;, D., Bos, P.H., Clark, A.J., Gough, M., Greenlee, M.L., et al.(2017). Synthetic study toward total synthesis of (±)-germine: Synthesis of (±)-4-methylenegermine . Organic Letters. 19. (19). p. 5150-5153.
Welsch, M.E., Kaplan, A., Chambers, J.M., Stokes, M.E., Bos, P.H., Zask, A., Zhang, Y., Sanchez-Martin, M., Badgley, M.A., Huang, C.S., et al.(2017). Multivalent Small-Molecule Pan-RAS Inhibitors . Cell. 168. (5). p. 878-889.e29.
Hornillos, V., Guduguntla, S., Fa&#241;an&#225;s-Mastral, M., P&#233;rez, M., Bos, P.H., Rudolph, A., Harutyunyan, S.R., Feringa, B.L.(2017). Cu-catalyzed enantioselective allylic alkylation with organolithium reagents . Nature Protocols. 12. (3). p. 493-505.
Pizzolato, S.F., Giannerini, M., Bos, P.H., Fa&#241;an&#225;s-Mastral, M., Feringa, B.L.(2015). Catalyst-controlled reverse selectivity in C-C bond formation: NHC-Cu-catalyzed α-selective allylic alkylation with organolithium reagents . Chemical Communications. 51. (38). p. 8142-8145.
Bos, P.H., Antalek, M.T., Porco, J.A., Stephenson, C.R.J.(2013). Tandem dienone photorearrangement-cycloaddition for the rapid generation of molecular complexity . Journal of the American Chemical Society. 135. (47). p. 17978-17982.
Fa&#241;an&#225;s-Mastral, M., P&#233;rez, M., Bos, P.H., Rudolph, A., Harutyunyan, S.R., Feringa, B.L.(2012). Enantioselective synthesis of tertiary and quaternary stereogenic centers: Copper/phosphoramidite-catalyzed allylic alkylation with organolithium reagents . Angewandte Chemie - International Edition. 51. (8). p. 1922-1925.
Bos, P.H., Rudolph, A., P&#233;rez, M., Fa&#241;an&#225;s-Mastral, M., Harutyunyan, S.R., Feringa, B.L.(2012). Copper-catalyzed asymmetric ring opening of oxabicyclic alkenes with organolithium reagents . Chemical Communications. 48. (12). p. 1748-1750.
P&#233;rez, M., Fa&#241;an&#225;s-Mastral, M., Hornillos, V., Rudolph, A., Bos, P.H., Harutyunyan, S.R., Feringa, B.L.(2012). Asymmetric allylic alkylation of acyclic allylic ethers with organolithium reagents . Chemistry - A European Journal. 18. (38). p. 11880-11883.
P&#233;rez, M., Fa&#241;an&#225;s-Mastral, M., Bos, P.H., Rudolph, A., Harutyunyan, S.R., Feringa, B.L.(2011). Catalytic asymmetric carbong-carbon bond formation via allylic alkylations with organolithium compounds . Nature Chemistry. 3. (5). p. 377-381.
Rudolph, A., Bos, P.H., Meetsma, A., Minnaard, A.J., Feringa, B.L.(2011). Catalytic asymmetric conjugate addition/oxidative dearomatization towards multifunctional spirocyclic compounds . Angewandte Chemie - International Edition. 50. (26). p. 5834-5838.
Bos, P.H., Bos, P.H., Maci&#225;, B., &#193;ngeles Fern&#225;ndez-Ib&#225;&#241;ez, M., Minnaard, A.J., Feringa, B.L.(2010). Catalytic asymmetric conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones . Organic and Biomolecular Chemistry. 8. (1). p. 47-49.
Bos, P.H., Minnaard, A.J., Feringa, B.L.(2008). Catalytic asymmetric conjugate addition of Grignard reagents to α,β-unsaturated sulfones . Organic Letters. 10. (19). p. 4219-4222.
Naito, J., Kuwahara, S., Watanabe, M., Decatur, J., Bos, P.H., Van Summeren, R.P., Ter Horst, B., Feringa, B.L., Minnaard, A.J., Harada, N.(2008). Stereoselective synthesis of 2,3,7-trimethylcyclooctanone and related compounds and determination of their relative and absolute contigurations by the MαNP acid method . Chirality. 20. (9). p. 1053-1065.