Profile Details

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Hire Dr. Paul Brown

USD 100 per hour

Norway

clinical research methodologist

Summary

I've worked in academic clinical research units (England, Canada and Norway) and the pharmaceutical industry (Australia, Denmark and Germany, including startups and multinationals). I'm internationally trained with degrees spanning biostatistics, pharmacology, toxicology, drug development and regulatory affairs, clinical trial design and medicine. I have substantial consultancy experience, working across various disease areas (mainly heart failure, diabetes, oncology, pediatrics) and all phases of research. I have over 20 years of SAS experience. I am on the Statistical Advisory Board for the Health Science Reports journal. I can assist with: -responding to reviewer comments after journal submission -writing the methods section of grant proposals (inc. study design) -preparation for thesis defence -SAS programming (inc. independent code validation) -data handling (inc. complex datasets e.g. administrative databases) -data analysis (e.g. survival analysis, multivariate analysis, risk modelling) -exploratory analyses -evaluating healthcare quality improvements -preparing visuals for conference presentations or journal submissions -statistical review e.g. draft papers for publication -regulatory submissions -meta-analysis

Subject Matter Expertise

• Research Methodology
• Consulting
• Biostatistics
• Clinical Trials
• Computer Programming
• Pharmaceutical Industry
• Pediatric Medicine
• Diabetes
• Health Data Analyst
• Meta-analysis
• Multivariate Analysis
• Drug Development
• Data Analytics
• Healthcare Consulting

Services

• Writing
• Scientific consulting
• Data Science
• Secondary Research
• Clinical Research Consulting
• Statistical review
• Experiment design

Work Experience

• Senior Biostatistical Consultant

  Alberta Children’s Hospital Research Institute

  April 2017 - Present

• Senior Consultant to the Pharmaceutical Industry

  Qualiance

  June 2013 - June 2014

Education

• PhD Medicine

  University of Alberta, Canada

  May 2014 - May 2017

• MSc Clinical Research

  Cardiff University, Wales

  May 2003 - May 2006

• MSc Biometry

  University of Reading, England

  May 1999 - May 2000

• First Class Honours in Mathematics & Statistics

  Griffith University, Australia

  May 1994 - May 1997

Publications

JOURNAL_ARTICLE
• {"ProfilePublicationId":41904,"Type":"JOURNAL_ARTICLE","Citation":"@article{PMID:28630372, Title= {Multitype Events and the Analysis of Heart Failure Readmissions: Illustration of a New Modeling Approach and Comparison With Familiar Composite End Points}, Author= {Brown, Paul M and Ezekowitz, Justin A}, DOI= {10.1161/circoutcomes.116.003382}, Number= {6}, Volume= {10}, Month= {June}, Year= {2017}, Journal= {Circulation. Cardiovascular quality and outcomes}, ISSN= {1941-7713}, URL= {https://doi.org/10.1161/CIRCOUTCOMES.116.003382}}\n\n","JournalTitle":"Circulation. Cardiovascular quality and outcomes","Title":"Multitype Events and the Analysis of Heart Failure Readmissions: Illustration of a New Modeling Approach and Comparison With Familiar Composite End Points","CitationType":"BIBTEX","DOI":"10.1161/circoutcomes.116.003382","Date":"2017-00-00","Url":"https://doi.org/10.1161/CIRCOUTCOMES.116.003382","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41905,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Brown2017e889, author= {Brown, P.M. and Ezekowitz, J.A.}, title= {Letter by Brown and Ezekowitz Regarding Article, \u0026quot;development and Evolution of a Hierarchical Clinical Composite End Point for the Evaluation of Drugs and Devices for Acute and Chronic Heart Failure: A 20-Year Perspective\u0026quot;}, journal= {Circulation}, year= {2017}, volume= {135}, number= {15}, pages= {e889-e891}, doi= {10.1161/CIRCULATIONAHA.116.026767}, note= {cited By 0}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017406384\u0026amp;doi=10.1161%2fCIRCULATIONAHA.116.026767\u0026amp;partnerID=40\u0026amp;md5=404c7b832540a224d2f75919c5b1526d}, document_type= {Letter}, source= {Scopus}}\n\n","JournalTitle":"Circulation","Title":"Letter by Brown and Ezekowitz Regarding Article, \u0026quot;development and Evolution of a Hierarchical Clinical Composite End Point for the Evaluation of Drugs and Devices for Acute and Chronic Heart Failure: A 20-Year Perspective\u0026quot;","CitationType":"BIBTEX","DOI":"10.1161/CIRCULATIONAHA.116.026767","Date":"2017-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017406384\u0026doi=10.1161%2fCIRCULATIONAHA.116.026767\u0026partnerID=40\u0026md5=404c7b832540a224d2f75919c5b1526d","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41906,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Brown2017, author= {Brown, P.M. and Ezekowitz, J.A.}, title= {Composite End Points in Clinical Trials of Heart Failure Therapy: How Do We Measure the Effect Size?}, journal= {Circulation: Heart Failure}, year= {2017}, volume= {10}, number= {1}, doi= {10.1161/CIRCHEARTFAILURE.116.003222}, art_number= {e003222}, note= {cited By 1}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010031041\u0026amp;doi=10.1161%2fCIRCHEARTFAILURE.116.003222\u0026amp;partnerID=40\u0026amp;md5=a9a8b8450b5dc3e8102fcf2f952639f1}, document_type= {Article}, source= {Scopus}}\n\n","JournalTitle":"Circulation: Heart Failure","Title":"Composite End Points in Clinical Trials of Heart Failure Therapy: How Do We Measure the Effect Size?","CitationType":"BIBTEX","DOI":"10.1161/CIRCHEARTFAILURE.116.003222","Date":"2017-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010031041\u0026doi=10.1161%2fCIRCHEARTFAILURE.116.003222\u0026partnerID=40\u0026md5=a9a8b8450b5dc3e8102fcf2f952639f1","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41907,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Raslan2017127, author= {Raslan, I.R. and Brown, P. and Westerhout, C.M. and Ezekowitz, J.A. and Hernandez, A.F. and Starling, R.C. and O\u0026#39;Connor, C. and McAlister, F.A. and Rowe, B.H. and Armstrong, P.W. and van Diepen, S.}, title= {Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score}, journal= {American Heart Journal}, year= {2017}, volume= {188}, pages= {127-135}, doi= {10.1016/j.ahj.2017.03.014}, note= {cited By 0}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017259815\u0026amp;doi=10.1016%2fj.ahj.2017.03.014\u0026amp;partnerID=40\u0026amp;md5=ad4f245f110b28ae64b6a8f197259166}, document_type= {Article}, source= {Scopus}}\n\n","JournalTitle":"American Heart Journal","Title":"Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score","CitationType":"BIBTEX","DOI":"10.1016/j.ahj.2017.03.014","Date":"2017-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017259815\u0026doi=10.1016%2fj.ahj.2017.03.014\u0026partnerID=40\u0026md5=ad4f245f110b28ae64b6a8f197259166","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41908,"Type":"JOURNAL_ARTICLE","Citation":"@article{Brown2017,title = {Multitype Events and the Analysis of Heart Failure Readmissions: Illustration of a New Modeling Approach and Comparison with Familiar Composite End Points},journal = {Circulation: Cardiovascular Quality and Outcomes},year = {2017},volume = {10},number = {6},author = {Brown, P.M. and Ezekowitz, J.A.}}","JournalTitle":"Circulation: Cardiovascular Quality and Outcomes","Title":"Multitype Events and the Analysis of Heart Failure Readmissions: Illustration of a New Modeling Approach and Comparison with Familiar Composite End Points","CitationType":"BIBTEX","DOI":"10.1161/CIRCOUTCOMES.116.003382","Date":"2017-00-00","Url":"http://www.scopus.com/inward/record.url?eid=2-s2.0-85021035918\u0026partnerID=MN8TOARS","PublicationContributors":null,"ContributorNames":"Brown, P.M., Ezekowitz, J.A.","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41909,"Type":"JOURNAL_ARTICLE","Citation":"@article{doi:10.1177/1471082X17746538, author= {Paul M Brown and Justin A Ezekowitz}, title= {Frailty modelling for multitype recurrent events in clinical trials}, journal= {Statistical Modelling}, volume= {0}, number= {0}, pages= {1471082X17746538}, year= {0}, doi= {10.1177/1471082X17746538}, URL= {https://doi.org/10.1177/1471082X17746538\n \n}, eprint= {https://doi.org/10.1177/1471082X17746538\n \n}, abstract= {Recurrent event outcomes are ubiquitous among clinical trial data which encourages a conventional approach to analysis. Yet a common feature of these data has received less attention, that is, survival times often comprise multiple types of events that may imply a disparity in cost and disease severity. Typically, we neglect this feature of the data by combining event-types or analyzing each type separately, thus ignoring any interdependence among them. This practice may reflect a dearth of readily available methods and software that more appropriately acknowledge the true data structure. We provide a review of the literature on multitype recurrent events and frailty modelling which reflects a renewed interest in the topic over the past decade and the emergence of software for estimation. Thus, a review of available methods seems timely, if not overdue. }}\n\n","JournalTitle":"Statistical Modelling","Title":"Frailty modelling for multitype recurrent events in clinical trials","CitationType":"BIBTEX","DOI":"10.1177/1471082X17746538","Date":"0-00-00","Url":"https://doi.org/10.1177/1471082X17746538","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41910,"Type":"JOURNAL_ARTICLE","Citation":"@article{doi:10.1177/1471082X17746538, author= {Paul M Brown and Justin A Ezekowitz}, title= {Frailty modelling for multitype recurrent events in clinical trials}, journal= {Statistical Modelling}, volume= {0}, number= {0}, pages= {1471082X17746538}, year= {0}, doi= {10.1177/1471082X17746538}, URL= {https://doi.org/10.1177/1471082X17746538\n \n}, eprint= {https://doi.org/10.1177/1471082X17746538\n \n}, abstract= {Recurrent event outcomes are ubiquitous among clinical trial data which encourages a conventional approach to analysis. Yet a common feature of these data has received less attention, that is, survival times often comprise multiple types of events that may imply a disparity in cost and disease severity. Typically, we neglect this feature of the data by combining event-types or analyzing each type separately, thus ignoring any interdependence among them. This practice may reflect a dearth of readily available methods and software that more appropriately acknowledge the true data structure. We provide a review of the literature on multitype recurrent events and frailty modelling which reflects a renewed interest in the topic over the past decade and the emergence of software for estimation. Thus, a review of available methods seems timely, if not overdue. }}\n\n","JournalTitle":"Statistical Modelling","Title":"Frailty modelling for multitype recurrent events in clinical trials","CitationType":"BIBTEX","DOI":"10.1177/1471082X17746538","Date":"0-00-00","Url":"https://doi.org/10.1177/1471082X17746538","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41911,"Type":"JOURNAL_ARTICLE","Citation":"@article{doi:10.1177/1471082X17746538, author= {Paul M Brown and Justin A Ezekowitz}, title= {Frailty modelling for multitype recurrent events in clinical trials}, journal= {Statistical Modelling}, volume= {0}, number= {0}, pages= {1471082X17746538}, year= {0}, doi= {10.1177/1471082X17746538}, URL= {https://doi.org/10.1177/1471082X17746538\n \n}, eprint= {https://doi.org/10.1177/1471082X17746538\n \n}, abstract= {Recurrent event outcomes are ubiquitous among clinical trial data which encourages a conventional approach to analysis. Yet a common feature of these data has received less attention, that is, survival times often comprise multiple types of events that may imply a disparity in cost and disease severity. Typically, we neglect this feature of the data by combining event-types or analyzing each type separately, thus ignoring any interdependence among them. This practice may reflect a dearth of readily available methods and software that more appropriately acknowledge the true data structure. We provide a review of the literature on multitype recurrent events and frailty modelling which reflects a renewed interest in the topic over the past decade and the emergence of software for estimation. Thus, a review of available methods seems timely, if not overdue. }}\n\n","JournalTitle":"Statistical Modelling","Title":"Frailty modelling for multitype recurrent events in clinical trials","CitationType":"BIBTEX","DOI":"10.1177/1471082X17746538","Date":"2017-10-00","Url":"https://doi.org/10.1177/1471082X17746538","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41912,"Type":"JOURNAL_ARTICLE","Citation":"@article{Browne004419, author= {Brown, Paul M. and Ezekowitz, Justin A.}, title= {Examining the Influence of Component Outcomes on the Composite at the Design Stage}, volume= {11}, number= {6}, year= {2018}, doi= {10.1161/CIRCOUTCOMES.117.004419}, publisher= {American Heart Association, Inc.}, issn= {1941-7705}, URL= {http://circoutcomes.ahajournals.org/content/11/6/e004419}, eprint= {http://circoutcomes.ahajournals.org/content/11/6/e004419.full.pdf}, journal= {Circulation: Cardiovascular Quality and Outcomes}}\n\n","JournalTitle":"Circulation: Cardiovascular Quality and Outcomes","Title":"Examining the Influence of Component Outcomes on the Composite at the Design Stage","CitationType":"BIBTEX","DOI":"10.1161/CIRCOUTCOMES.117.004419","Date":"2018-00-00","Url":"http://circoutcomes.ahajournals.org/content/11/6/e004419","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41913,"Type":"JOURNAL_ARTICLE","Citation":"@article{Browne004419, author= {Brown, Paul M. and Ezekowitz, Justin A.}, title= {Examining the Influence of Component Outcomes on the Composite at the Design Stage}, volume= {11}, number= {6}, year= {2018}, doi= {10.1161/CIRCOUTCOMES.117.004419}, publisher= {American Heart Association, Inc.}, issn= {1941-7705}, URL= {http://circoutcomes.ahajournals.org/content/11/6/e004419}, eprint= {http://circoutcomes.ahajournals.org/content/11/6/e004419.full.pdf}, journal= {Circulation: Cardiovascular Quality and Outcomes}}\n\n","JournalTitle":"Circulation: Cardiovascular Quality and Outcomes","Title":"Examining the Influence of Component Outcomes on the Composite at the Design Stage","CitationType":"BIBTEX","DOI":"10.1161/CIRCOUTCOMES.117.004419","Date":"2018-00-00","Url":"http://circoutcomes.ahajournals.org/content/11/6/e004419","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41914,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Reid2015, author= {Reid, R. and Ezekowitz, J.A. and Brown, P.M. and McAlister, F.A. and Rowe, B.H. and Braam, B.}, title= {The prognostic importance of changes in renal function during treatment for acute heart failure depends on admission renal function}, journal= {PLoS ONE}, year= {2015}, volume= {10}, number= {9}, doi= {10.1371/journal.pone.0138579}, art_number= {e0138579}, note= {cited By 2}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946599706\u0026amp;doi=10.1371%2fjournal.pone.0138579\u0026amp;partnerID=40\u0026amp;md5=877099567d022b6d98700976f68b6598}, document_type= {Article}, source= {Scopus}}\n\n","JournalTitle":"PLoS ONE","Title":"The prognostic importance of changes in renal function during treatment for acute heart failure depends on admission renal function","CitationType":"BIBTEX","DOI":"10.1371/journal.pone.0138579","Date":"2015-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946599706\u0026doi=10.1371%2fjournal.pone.0138579\u0026partnerID=40\u0026md5=877099567d022b6d98700976f68b6598","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41915,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Gouda20161032, author= {Gouda, P. and Brown, P. and Rowe, B.H. and McAlister, F.A. and Ezekowitz, J.A.}, title= {Insights into the importance of the electrocardiogram in patients with acute heart failure}, journal= {European Journal of Heart Failure}, year= {2016}, volume= {18}, number= {8}, pages= {1032-1040}, doi= {10.1002/ejhf.561}, note= {cited By 2}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981709090\u0026amp;doi=10.1002%2fejhf.561\u0026amp;partnerID=40\u0026amp;md5=d4b2df5a8aa02686e561242b9247db26}, document_type= {Article}, source= {Scopus}}\n\n","JournalTitle":"European Journal of Heart Failure","Title":"Insights into the importance of the electrocardiogram in patients with acute heart failure","CitationType":"BIBTEX","DOI":"10.1002/ejhf.561","Date":"2016-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-84981709090\u0026doi=10.1002%2fejhf.561\u0026partnerID=40\u0026md5=d4b2df5a8aa02686e561242b9247db26","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41916,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Davidson20091641, author= {Davidson, J.A. and Liebl, A. and Christiansen, J.S. and Fulcher, G. and Ligthelm, R.J. and Brown, P. and Gylvin, T. and Kawamori, R.}, title= {Risk for nocturnal hypoglycemia with biphasic insulin aspart 30 compared with biphasic human insulin 30 in adults with type 2 diabetes mellitus: A meta-analysis}, journal= {Clinical Therapeutics}, year= {2009}, volume= {31}, number= {8}, pages= {1641-1651}, doi= {10.1016/j.clinthera.2009.08.011}, note= {cited By 45}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-72449165113\u0026amp;doi=10.1016%2fj.clinthera.2009.08.011\u0026amp;partnerID=40\u0026amp;md5=236cf441638047340b861e0356463043}, document_type= {Review}, source= {Scopus}}\n\n","JournalTitle":"Clinical Therapeutics","Title":"Risk for nocturnal hypoglycemia with biphasic insulin aspart 30 compared with biphasic human insulin 30 in adults with type 2 diabetes mellitus: A meta-analysis","CitationType":"BIBTEX","DOI":"10.1016/j.clinthera.2009.08.011","Date":"2009-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-72449165113\u0026doi=10.1016%2fj.clinthera.2009.08.011\u0026partnerID=40\u0026md5=236cf441638047340b861e0356463043","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41917,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Brown20075, author= {Brown, P.M.}, title= {What is the logic in mixing data and beliefs?}, journal= {Pharmaceutical Statistics}, year= {2007}, volume= {6}, number= {1}, pages= {5-8}, doi= {10.1002/pst.256}, note= {cited By 0}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947390459\u0026amp;doi=10.1002%2fpst.256\u0026amp;partnerID=40\u0026amp;md5=04d9aa1db61824289898bae661a2ef2a}, document_type= {Review}, source= {Scopus}}\n\n","JournalTitle":"Pharmaceutical Statistics","Title":"What is the logic in mixing data and beliefs?","CitationType":"BIBTEX","DOI":"10.1002/pst.256","Date":"2007-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947390459\u0026doi=10.1002%2fpst.256\u0026partnerID=40\u0026md5=04d9aa1db61824289898bae661a2ef2a","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41918,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Brown20161356, author= {Brown, P.M. and Anstrom, K.J. and Felker, G.M. and Ezekowitz, J.A.}, title= {Composite End Points in Acute Heart Failure Research: Data Simulations Illustrate the Limitations}, journal= {Canadian Journal of Cardiology}, year= {2016}, volume= {32}, number= {11}, pages= {1356}, doi= {10.1016/j.cjca.2016.02.067}, note= {cited By 5}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994184221\u0026amp;doi=10.1016%2fj.cjca.2016.02.067\u0026amp;partnerID=40\u0026amp;md5=3ee21b994c12e95785a8ee42dac5c0ed}, document_type= {Review}, source= {Scopus}}\n\n","JournalTitle":"Canadian Journal of Cardiology","Title":"Composite End Points in Acute Heart Failure Research: Data Simulations Illustrate the Limitations","CitationType":"BIBTEX","DOI":"10.1016/j.cjca.2016.02.067","Date":"2016-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994184221\u0026doi=10.1016%2fj.cjca.2016.02.067\u0026partnerID=40\u0026md5=3ee21b994c12e95785a8ee42dac5c0ed","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41919,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Brown2017215, author= {Brown, P.M. and Ezekowitz, J.A.}, title= {Power and sample size estimation for nonparametric composite endpoints: Practical implementation using data simulations}, journal= {Journal of Modern Applied Statistical Methods}, year= {2017}, volume= {16}, number= {2}, pages= {215-230}, doi= {10.22237/jmasm/1509495120}, note= {cited By 0}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037055070\u0026amp;doi=10.22237%2fjmasm%2f1509495120\u0026amp;partnerID=40\u0026amp;md5=e2d7e7d89ae73376ecff1531bdec68a7}, document_type= {Article}, source= {Scopus}}\n\n","JournalTitle":"Journal of Modern Applied Statistical Methods","Title":"Power and sample size estimation for nonparametric composite endpoints: Practical implementation using data simulations","CitationType":"BIBTEX","DOI":"10.22237/jmasm/1509495120","Date":"2017-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037055070\u0026doi=10.22237%2fjmasm%2f1509495120\u0026partnerID=40\u0026md5=e2d7e7d89ae73376ecff1531bdec68a7","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}
• {"ProfilePublicationId":41920,"Type":"JOURNAL_ARTICLE","Citation":"@ARTICLE{Brown2017215, author= {Brown, P.M. and Ezekowitz, J.A.}, title= {Power and sample size estimation for nonparametric composite endpoints: Practical implementation using data simulations}, journal= {Journal of Modern Applied Statistical Methods}, year= {2017}, volume= {16}, number= {2}, pages= {215-230}, doi= {10.22237/jmasm/1509495120}, note= {cited By 0}, url= {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037055070\u0026amp;doi=10.22237%2fjmasm%2f1509495120\u0026amp;partnerID=40\u0026amp;md5=e2d7e7d89ae73376ecff1531bdec68a7}, document_type= {Article}, source= {Scopus}}\n\n","JournalTitle":"Journal of Modern Applied Statistical Methods","Title":"Power and sample size estimation for nonparametric composite endpoints: Practical implementation using data simulations","CitationType":"BIBTEX","DOI":"10.22237/jmasm/1509495120","Date":"2017-00-00","Url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037055070\u0026doi=10.22237%2fjmasm%2f1509495120\u0026partnerID=40\u0026md5=e2d7e7d89ae73376ecff1531bdec68a7","PublicationContributors":null,"ContributorNames":"","TotalNumberOfPublications":0}