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Hire Dr. Margaret S.

United States

Profile Summary

I use proteomics and molecular biology methods in my research on brain tumors and brain AVMs, as well as cell/tissue culture and immunostaining . I’m interested in utilizing proteomics and molecular biology in biomarker discovery and drug development of diseases, such as Brain Tumors, Brain AVMs, Cardiovascular diseases, etc. - My novel research on brain AVMs was the first to utilize proteomics techniques to identify protein targets for AVM molecular and vascular therapies post radiosurgery. selected PUBLICATIONS Margaret Simonian (2016). Proteomics and Molecular Medicine, Editorial. Journal of Integrative Molecular Medicine. V3, issue 3, P 732 Margaret Simonian (2016). Proteomics in Medicine, Editorial. Journal of Data Mining in Genomics & Proteomics. Volume 7 Issue 3. DOI: 10.4172/2153-0602.1000e126 Garni Barkhoudarian, Julian P.Whitelegge, Daniel F. Kelly, Margaret Simonian (2016). Proteomics analysis of brain meningiomas in pursuit of novel biomarkers of the aggressive behavior. J. Proteomics and Bioinformatics, 9 (2): 53-57 Margaret Simonian (2015). Cerebral Arteriovenous Malformations (AVMs): Causes, Treatment and Research. MOJ proteomics and Bioinformatics. v 2, issue 5. DOI: 10.15406/mojpb.2015.02.00061 Margaret Simonian, Rachel R Ogorzalek Loo, Joseph A Loo, Marcus A Stoodley and Mark P Molloy (2014). Proteomics Detection of Endothelial Cell Surface Proteins Following Irradiation as Potential Targets for Brain Arteriovenous Malformations Molecular Therapy. MOJ Proteomics and Bioinformatics. v1, issue 1. http://medcraveonline.com/MOJPB/MOJPB-01-00002.pdf Margaret Simonian, Mark P Molloy and Marcus A Stoodley (2012). In vitro and in vivo biotinylation of endothelial cell surface proteins in the pursuit of targets for vascular therapies for brain AVMs. Metabolomics Journal. issue 1; http://dx.doi.org/10.4172/2153-0769.S1-007 Margaret Simonian, Nalaka Rannulu, Rachel R Ogorzalek Loo, Joseph A Loo, Mark P Molloy and Marcus A Stoodley (2015). Identification of protein targets for brain arteriovenous malformations (AVMs) molecular therapies. J Proteomics, submitted. Margaret Simonian, Dyna Shirasaki, Rachel R Ogorzalek Loo, Joseph Loo, Mark P Molloy and Marcus A Stoodley (2015). Proteomics identification of radiation-induced changes of membrane proteins in the rat model of arteriovenous malformations. Submitted. J of Neurosurgery, submitted Margaret Simonian, Sham V. Nair, John A. Nell, David A. Raftos (2009). Proteomic analysis of QX-disease resistance markers in Sydney rock oysters (Saccostrea glomerata). Journal of Proteomics. 73, p (209-217). Margaret Simonian, Sham V. Nair, Wayne O’Connor, David A. Raftos . (2009). Protein markers of Martielia sydneyi infection in Sydney rock oysters (Saccostrea glomerata). Journal of Fish Diseases. 32, (367-375). I'm a Reviewer for the following scientific journals - Journal of Proteomics, since 2012 - Journal of Arthritis and Research Therapy, since 2011 - Journal of European Proteomics, since 2013 Editor: SciFed Journal of Protein Science Research Editorial Board Member; Journal of Data Mining in Genomics & Proteomics Editorial Board Member; Science publications Associate Editor, Journal of Applied Biotechnology and Bioengineering Organizing Committee Member; International Conference on Precision Medicine. [Dec 5-7, 2016 San Antonio, USA]

Subject Matter Expertise

• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ Data Mining
• ☆ Protein/Enzyme Engineering
• ☆ Drug Development
• ☆ Precision Medicine
• ☆ Neurosurgery
• ☆ Cardiovascular Disease

Services

• Research

Research Systematic Literature Review

Work Experience

Proteomics Consultant

UCLA , Dept of Neurosurgery

July 2016 - Present

Research Scholar/Scientist

UCLA

January 2012 - December 2015

Research Scientist (Proteomics projects: Brain AVM’s )

MACQUARIE UNIVERSITY, SCHOOL OF ADVANCED MEDICINE, AND BIOLOGICAL SCINCES

January 2007 - December 2007

Medical Lab Scientist in Blood Bank/Hematology Department

Royal Prince Alfred Hospital (Sydney, Australia)

January 2002 - January 2004

Medical Lab Scientist, Hematology and Biochemistry

Dougla Hanly Moir Pathology (Sydney-Australia)

January 2000 - January 2002

Education

MPhil and PhD

UCLA and Macquarie Uni

February 2006 - January 2015

Certifications

• Certification details not provided.