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Hire Dr. Lee Baker

United Kingdom

CEO - Chi-Squared Innovations ★ Telling Stories With Data ★ www.chi2innovations.com

Profile Summary

I have a very broad range of expertise within science, having in-depth knowledge of physics, medical physics, bioinformatics, medicine, artificial intelligence, computer programming, mathematics and statistics. Having left academia to form a start-up company, I now work as CEO and Chief Data Scientist for Chi-Squared Innovations - an innovative company that creates automated, visually intuitive statistical applications that save time and money.

Subject Matter Expertise

• ☆ Data Analysis
• ☆ Bioinformatics
• ☆ Health & Medicine (General)
• ☆ Probability & Statistics
• ☆ Biostatistics
• ☆ Physics
• ☆ Computer Programming
• ☆ Mathematics
• ☆ Artificial Intelligence
• ☆ Medical Informatics
• ☆ Visualization

Services

• Writing
• Data Science
• Clinical Research Consulting
• Statistical review

Work Experience

• CEO & Chief Data Scientist

  Chi-Squared Innovations

  May 2012 - Present

• Statistical Programmer

  University of Dundee

  May 2006 - March 2013

• Data Analyst

  University of Abertay Dundee

  November 2004 - April 2006

Education

• PhD Artificial Intelligence (Computing)

  University of Abertay Dundee

  September 2001 - November 2005

• MSc Bioinformatics (Computing)

  University of Abertay Dundee

  September 2000 - September 2001

• MSc Medical Physics (Medical Physics)

  University of Aberdeen

  September 1999 - September 2000

• BSc Physics (Physics)

  Swansea University

  September 1991 - June 1994

Publications

JOURNAL ARTICLE
• (2013). Multiparameter DNA content analysis identifies distinct groups in primary breast cancer. British journal of cancer. 108. (4). p. 873--880. Nature Publishing Group
• (2013). Pattern of brain metastatic disease according to HER-2 and ER receptor status in breast cancer patients. Clinical radiology. 68. (10). p. 1070--1073. Elsevier
• (2013). Prospective parallel randomized trial of the MultiCyte™ ThinPrep® imaging system: the Scottish experience. Cytopathology. 24. (4). p. 235--245. Wiley Online Library
• (2012). Changing hospital culture: the role of an acute palliative care unit. BMJ Supportive & Palliative Care. 2. (Suppl 1). p. A88--A89. British Medical Journal Publishing Group
• Kelly, P and Paulin, F and Lamont, D and Baker, L and Clearly, S and Exon, D and Thompson, A(2012). Pre-treatment plasma proteomic markers associated with survival in oesophageal cancer. British journal of cancer. 106. (5). p. 955--961. Nature Publishing Group
• (2012). Short-stay, specialist beds in a UK teaching hospital as a model to integrate palliative care into the acute hospital culture. The journal of the Royal College of Physicians of Edinburgh. 42. (1). p. 8--14.
• (2012). Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification. British journal of cancer. 107. (2). p. 224--229. Nature Publishing Group
• Christie, Lesley J and MacKenzie, Carol and Palmer, Timothy J and Baker, Lee and Goodlad, John R(2011). Type and maturational status of dendritic cells in cutaneous B cell lymphoproliferative disorders. Histopathology. 59. (3). p. 421--432. Wiley Online Library
• Eadie, A and Whelehan, P and Baker, L and Berg, J and Evans, A(2011). Improving the validity of breast density assessment. Breast Cancer Research. 13. p. 1--13. BioMed Central
• (2011). Prevalence and predictors of supportive care needs in lung cancer patients. BMJ Supportive & Palliative Care. 1. (Suppl 1). p. A18--A19. British Medical Journal Publishing Group
• (2011). FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype. BMC research notes. 4. (1). p. 72. BioMed Central Ltd
• (2010). Quantitative shear wave ultrasound elastography: initial experience in solid breast masses. Breast Cancer Res. 12. (6). p. R104.
• (2010). Perceptions of anxiety in lung cancer patients and their support network. Supportive care in cancer. 18. (1). p. 29--36. Springer
• (2010). Abstract P3-12-11: Combining Genotype at Low Penetrance Breast Cancer Loci with Family History Risk Leads to Significant Risk Reclassification. Cancer Research. 70. (24 Supplement). p. P3--12. AACR
• (2010). Gene expression in colorectal neoplasia: modifications induced by tissue ischaemic time and tissue handling protocol. Histopathology. 56. (2). p. 240--250. Wiley Online Library
• (2010). Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based study. British journal of cancer. 103. (4). p. 475--481. Nature Publishing Group
• (2010). The RNA helicase p68 modulates expression and function of the $Δ$133 isoform (s) of p53, and is inversely associated with $Δ$133p53 expression in breast cancer. Oncogene. 29. (49). p. 6475--6484. Nature Publishing Group
• (2009). NF-kB Complex Activation and Association of $α$B-Crystallin and Vimentin with Poor Prognosis in Primary Breast Cancer. Cancer research. 69. (24 Supplement). p. 2143--2143. AACR
• (2009). Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction. British Journal of Surgery. 96. (10). p. 1135--1140. Wiley Online Library
• (2009). The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer. British journal of cancer. 100. (10). p. 1687--1696. Nature Publishing Group
• Hadad, Sirwan M and Baker, Lee and Quinlan, Philip R and Robertson, Katherine E and Bray, Susan E and Thomson, George and Kellock, David and Jordan, Lee B and Purdie, Colin A and Hardie, David G and others(2009). Histological evaluation of AMPK signalling in primary breast cancer. BMC cancer. 9. (1). p. 1. BioMed Central
• (2009). PP59 Prognostic significance of aB-crystallin, vimentin and HSP 27 association in primary breast cancer. European Journal of Cancer Supplements. 7. (4). p. 31. Elsevier
• (2009). Suspected malignant cord compression--improving time to diagnosis via a ‘hotline’: a prospective audit. British journal of cancer. 100. (12). p. 1867--1872. Nature Publishing Group
• (2008). Specialist palliative care provision in a major teaching hospital and cancer centre-an eight-year experience. JOURNAL-ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH. 38. (2). p. 112. Royal College of Physicians of Edinburgh.
• (2008). The wisdom of crowds—ensembles and modules in environmental modelling. Geoderma. 147. (1). p. 1--7. Elsevier
• Lain, Sonia and Hollick, Jonathan J and Campbell, Johanna and Staples, Oliver D and Higgins, Maureen and Aoubala, Mustapha and McCarthy, Anna and Appleyard, Virginia and Murray, Karen E and Baker, Lee and others(2008). Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer cell. 13. (5). p. 454--463. Elsevier
• (2007). Delay from symptom onset increases the conversion rate in laparoscopic cholecystectomy for acute cholecystitis. World journal of surgery. 31. (6). p. 1300--1303. Springer
• (2007). The clinical relevance of p53 isoforms modifying the effects of p53 mutation on survival from breast cancer. ASCO Annual Meeting Proceedings. 25. (18\_suppl). p. 10505.
• McCallum, Stephen J and Welch, Andrew E and Baker, Lee(2001). A digital phantom of the axilla based on the Visible Human Project data set. Nuclear Science, IEEE Transactions on. 48. (4). p. 1418--1422. IEEE

CONFERENCE PAPER
• (2011). Prognostic impact of P53 expression in oesophageal adenocarcinoma. BRITISH JOURNAL OF SURGERY. 98. p. 24--25.
• (2011). Final analysis of the NEOMET trial of neoadjuvant metformin: examining effects on Ki67, gene expression, and pathway analysis in primary operable breast cancer. JOURNAL OF CLINICAL ONCOLOGY. 29. (15).
• Merrick, C and Dunlop, J and Baker, L and Gellatly, E and Martin, A and Quinlan, P and Tavendale, R and Thompson, AM and Palmer, C and Reis, M and others(2011). Identifying women at increased risk of breast cancer; Can we use genotyping at low penetrance loci?. JOURNAL OF CLINICAL ONCOLOGY. 29. (27).
• (2009). Gene expression of 3R in breast tumors from the CAPS01 protocol. BULLETIN DU CANCER. 96. p. S32--S33.
• (2007). Post-operative radiotherapy does not adversely affect the outcome of autologous free abdominal nap breast reconstruction. BREAST CANCER RESEARCH AND TREATMENT. 106. p. S195--S195.
• Hadad, SM and Robertson, KE and Baker, L and Bray, SE and Purdie, CA and Jordan, L and Vendrell, JA and Cohen, PA and Thomson, AM(2007). Identification of IGFBP4 as a marker of tamoxifen failure in primary breast cancer. BREAST CANCER RESEARCH AND TREATMENT. 106. p. S64--S64.