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USD 100 /hr

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Hire Dr. Leacky K.

Netherlands

USD 100 /hr

Freelance Statistician| Expert in Bayesian analysis, R & SAS programming, Shiny Apps Non-clinical statistics support,

Profile Summary

Expert Biostatistician in diverse applications of Statistics, proficient R programmer and Shiny Apps developer, automated reporting with RMarkdown,

Subject Matter Expertise

• ★ Biostatistics
• ★ Regression Analysis
• ☆ Nonlinear Regression
• ☆ Bayesian Statistics

Services

• Writing
• Data & AI
• Product Development

Writing Technical Writing

Data & AI Statistical Analysis, Algorithm Design-Non ML, Data Visualization

Product Development Formulation, Stability/Shelf Life Testing

Work Experience

Senior Biostatistician

Janssen (Netherlands)

August 2016 - Present

Education

Master of Biostatistics (The Interuniversity Institute for Biostatistics and statistical Bioinformatics (I-BioStat))

Universiteit Hasselt - Campus Diepenbeek

September 2010 - September 2012

Bachelor of Science in Mathematics and Computer Science (Pure and Applied Mathematics)

Jomo Kenyatta University of Agriculture and Technology

August 2004 - July 2008

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2018). A Closer Look on Spatiotemporal Variations of Dissolved Oxygen in Waste Stabilization Ponds Using Mixed Models . Water.

Long Ho, Duy Pham, Wout Van Echelpoel, Leacky Muchene, Ziv Shkedy, Andres Alvarado, Juan Espinoza-Palacios, Maria Arevalo-Durazno, Olivier Thas, Peter Goethals(2018). A Closer Look on Spatiotemporal Variations of Dissolved Oxygen in Waste Stabilization Ponds Using Mixed Models . Water. 10. (2). p. 201. {MDPI} {AG}

Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid β-induced pathology. @article{1817, title= {Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid β-induced pathology.}, journal= {Alzheimer{\textquoteright}s Research \& Therapy }, year= {In Press}, author= {Jelle Praet and Nikolay Manyakov and Leacky Muchene and Zhenhua Mai and Vasilis Terzopoulos and Steve De Backer and An Torremans and P.J. Guns and Tom Van De Casteele and Astrid Bottelbergs and Bianca Van Broeck and Jan Sijbers and Dirk Smeets and Ziv Shkedy and Luc Bijnens and Darrel Pemberton and Mark Schmidt and Annemie Van Der Linden and Marleen Verhoye}} . Alzheimer Research & Therapy.

S{\'{a}}nchez, L and Muchene, L and Luaces, P and Viada, C and Rodr{\'{i}}guez, P C and Frias, A and Shkedy, Z and Lage, A(2017). Evaluating The Effect Of Immunotherapy In Advanced Non-Small- Cell Lung Cancer Patients Using Two Components Mixture Model . Value in Health. 17. (7). p. A566. Elsevier

Jake Olivier(2017). Applied surrogate endpoint evaluation methods with {SAS} and R. Ariel~Alonso, Theophile~Bigirumurame, Tomasz~Burzykowski, Marc~Buyse, Geert~Molenberghs, Leacky~Muchene, Nolen Joy~Perualila, Ziv~Shkedy, Wim~Van der Elst, Chapman {\&} Hall/{CRC} Biostatics Series, . Statistics in Medicine. 36. (24). p. 3919--3920. Wiley-Blackwell

P. Luaces, L. Sanchez, C. Viada, P.C. Rodriguez, M. Alvarez, C. Fonte, L. Muchene, S. Shkedy, A. Lage(2015). Identification and Characterization of Long Term Survival Population In Non-Small-Cell Lung Cancer Patients Treated With Immunotherapies . Value in Health. 18. (3). p. A193. Elsevier {BV}

CONFERENCE PAPER

(2016). Evaluation of Magnetic Resonance Imaging (MRI) Parameters as Biomarkers in Alzheimer's Disease. The Joint Statistical Meetings (JSM), Chicago, USA.

(2015). Estimation of order- restricted mean structure for independent and correlated data using Bayesian Variable Selection (BVS) models. 30th International Workshop on Statistical Modelling (IWSM), Linz, Austria.

(2014). Determination of the minimum effective dose for correlated dose-response data using Bayesian variable selection (BVS) models. Non-Clinical Statistics Conference (NCS) 2014, Brugge,Belgium.

(2013). Joint modelling of HCV and HBV co-infection amongst drug users in Belgium, using individual cross-sectional data. 21st Meeting of the Belgian Statistical Society(BSS) 2013, Ghent, Belgium.

DISSERTATION THESIS

Muchene, Leacky(2016). Statistical Modelling in Non-clinical Pharmaceutical Research.

CONFERENCE POSTER

(2014). Determination of the minimum eective dose for correlated dose-response data using Bayesian variable selection (BVS) models. 35th Annual Conference of the International Society for Clinical Biostatistics (ISCB), Vi- enna, Austria.