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Profile Details
Subject Matter Expertise
Services
Work Experience
Assistant Professor
University of Ottawa
2015 - Present 
Research Scientist
IBM Almaden Research Center
2012 - 2014
Postdoctoral Fellow
University of California Berkeley
2010 - 2012
Education
Ph.D. Organic Chemistry (Chemistry)
Massachusetts Institute of Technology
2005 - 2010
B.S. Chemistry (Chemistry)
University of Illinois at Urbana-Champaign
2001 - 2005
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
(2018). Water-Dispersible Bismuth–Organic Materials with Computed Tomography Contrast Properties . ACS Applied Bio Materials.
(2018). Using the Negative Hyperconjugation Effect of Pentafluorosulfanyl Acceptors to Enhance Two-Photon Absorption in Push–Pull Chromophores . Chemistry of Materials.
Liu, S., Ono, R.J., Wu, H., Teo, J.Y., Liang, Z.C., Xu, K., Zhang, M., Zhong, G., Tan, J.P.K., Ng, M., et al.(2017). Highly potent antimicrobial polyionenes with rapid killing kinetics, skin biocompatibility and in vivo bactericidal activity . Biomaterials. 127. p. 36-48.
Gautam, P., Yu, C.P., Zhang, G., Hillier, V.E., Chan, J.M.W.(2017). Pulling with the Pentafluorosulfanyl Acceptor in Push-Pull Dyes . Journal of Organic Chemistry. 82. (20). p. 11008-11020.
Zhang, G., Chan, J.M.W.(2017). Reversibly thermochromic bismuth-organic materials with tunable optical gaps . Journal of Materials Chemistry C. 5. (38). p. 10007-10015.
Chan, J.M.W., Wojtecki, R.J., Sardon, H., Lee, A.L.Z., Smith, C.E., Shkumatov, A., Gao, S., Kong, H., Yang, Y.Y., Hedrick, J.L.(2017). Self-Assembled, Biodegradable Magnetic Resonance Imaging Agents: Organic Radical-Functionalized Diblock Copolymers . ACS Macro Letters. 6. (2). p. 176-180.
Ong, Z.Y., Coady, D.J., Tan, J.P.K., Li, Y., Chan, J.M.W., Yang, Y.Y., Hedrick, J.L.(2016). Design and synthesis of biodegradable grafted cationic polycarbonates as broad spectrum antimicrobial agents . Journal of Polymer Science, Part A: Polymer Chemistry. 54. (8). p. 1029-1035.
Chan, J.M.W., Tan, J.P.K., Engler, A.C., Ke, X., Gao, S., Yang, C., Sardon, H., Yang, Y.Y., Hedrick, J.L.(2016). Organocatalytic Anticancer Drug Loading of Degradable Polymeric Mixed Micelles via a Biomimetic Mechanism . Macromolecules. 49. (6). p. 2013-2021.
Sardon, H., Tan, J.P.K., Chan, J.M.W., Mantione, D., Mecerreyes, D., Hedrick, J.L., Yang, Y.Y.(2015). Thermoresponsive random poly(ether urethanes) with tailorable LCSTs for anticancer drug delivery . Macromolecular Rapid Communications. 36. (19). p. 1761-1767.
Chan, J.M.W., Zhang, X., Brennan, M.K., Sardon, H., Engler, A.C., Fox, C.H., Frank, C.W., Waymouth, R.M., Hedrick, J.L.(2015). Organocatalytic ring-opening polymerization of trimethylene carbonate to yield a biodegradable polycarbonate . Journal of Chemical Education. 92. (4). p. 708-713.
Pascual, A., Tan, J.P.K., Yuen, A., Chan, J.M.W., Coady, D.J., Mecerreyes, D., Hedrick, J.L., Yang, Y.Y., Sardon, H.(2015). Broad-Spectrum Antimicrobial Polycarbonate Hydrogels with Fast Degradability . Biomacromolecules. 16. (4). p. 1169-1178.
Xu, Q., Sardon, H., Chan, J.M.W., Hedrick, J.L., Yang, Y.Y.(2015). Polyurethane-coated silica particles with broad-spectrum antibacterial properties . Polymer Chemistry. 6. (11). p. 2011-2022.
Engler, A.C., Ke, X., Gao, S., Chan, J.M.W., Coady, D.J., Ono, R.J., Lubbers, R., Nelson, A., Yang, Y.Y., Hedrick, J.L.(2015). Hydrophilic polycarbonates: Promising degradable alternatives to poly(ethylene glycol)-based stealth materials . Macromolecules. 48. (6). p. 1673-1678.
Chan, J.M.W., Ke, X., Sardon, H., Engler, A.C., Yang, Y.Y., Hedrick, J.L.(2014). Chemically modifiable N-heterocycle-functionalized polycarbonates as a platform for diverse smart biomimetic nanomaterials . Chemical Science. 5. (8). p. 3294-3300.
Ng, V.W.L., Chan, J.M.W., Sardon, H., Ono, R.J., García, J.M., Yang, Y.Y., Hedrick, J.L.(2014). Antimicrobial hydrogels: A new weapon in the arsenal against multidrug-resistant infections . Advanced Drug Delivery Reviews. 78. p. 46-62.
Sardon, H., Chan, J.M.W., Ono, R.J., Mecerreyes, D., Hedrick, J.L.(2014). Highly tunable polyurethanes: Organocatalyzed polyaddition and subsequent post-polymerization modification of pentafluorophenyl ester sidechains . Polymer Chemistry. 5. (11). p. 3547-3550.
Liu, S.Q., Venkataraman, S., Ong, Z.Y., Chan, J.M.W., Yang, C., Hedrick, J.L., Yang, Y.Y.(2014). Overcoming multidrug resistance in microbials using nanostructures self-assembled from cationic bent-core oligomers . Small. 10. (20). p. 4130-4135.
Ke, X., Ng, V.W.L., Ono, R.J., Chan, J.M.W., Krishnamurthy, S., Wang, Y., Hedrick, J.L., Yang, Y.Y.(2014). Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles . Journal of Controlled Release. 193. p. 9-26.
Engler, A.C., Chan, J.M.W., Coady, D.J., O'Brien, J.M., Sardon, H., Nelson, A., Sanders, D.P., Yang, Y.Y., Hedrick, J.L.(2013). Accessing new materials through polymerization and modification of a polycarbonate with a pendant activated ester . Macromolecules. 46. (4). p. 1283-1290.
Sardon, H., Engler, A.C., Chan, J.M.W., Coady, D.J., O'Brien, J.M., Mecerreyes, D., Yang, Y.Y., Hedrick, J.L.(2013). Homogeneous isocyanate- and catalyst-free synthesis of polyurethanes in aqueous media . Green Chemistry. 15. (5). p. 1121-1126.
Sardon, H., Engler, A.C., Chan, J.M.W., García, J.M., Coady, D.J., Pascual, A., Mecerreyes, D., Jones, G.O., Rice, J.E., Horn, H.W., et al.(2013). Organic acid-catalyzed polyurethane formation via a dual-activated mechanism: Unexpected preference of n-activation over o-activation of isocyanates . Journal of the American Chemical Society. 135. (43). p. 16235-16241.
Engler, A.C., Chan, J.M.W., Fukushima, K., Coady, D.J., Yang, Y.Y., Hedrick, J.L.(2013). Polycarbonate-based brush polymers with detachable disulfide-linked side chains . ACS Macro Letters. 2. (4). p. 332-336.
Chan, J.M.W., Bauer, S., Sorek, H., Sreekumar, S., Wang, K., Toste, F.D.(2013). Studies on the vanadium-catalyzed nonoxidative depolymerization of Miscanthus giganteus-derived lignin . ACS Catalysis. 3. (6). p. 1369-1377.
Chan, J.M.W., Sardon, H., Engler, A.C., García, J.M., Hedrick, J.L.(2013). Tetra- N -Butylammonium fluoride as an efficient transesterification catalyst for functionalizing cyclic carbonates and aliphatic polycarbonates . ACS Macro Letters. 2. (10). p. 860-864.
Chan, J.M.W., Amarante, G.W., Toste, F.D.(2011). Tandem cycloisomerization/Suzuki coupling of arylethynyl MIDA boronates . Tetrahedron. 67. (24). p. 4306-4312.
Chan, J.M.W., Kooi, S.E., Swager, T.M.(2010). Synthesis of stair-stepped polymers containing dibenz[a, h]anthracene subunits . Macromolecules. 43. (6). p. 2789-2793.
Chan, J.M.W., Tischler, J.R., Kooi, S.E., Bulović, V., Swager, T.M.(2009). Synthesis of j-aggregating dibenz[a,j]anthracene-based macrocycles . Journal of the American Chemical Society. 131. (15). p. 5659-5666.
Song, Y., Chan, J.M.W., Tovian, Z., Secrest, A., Nagy, E., Krysiak, K., Bergan, K., Parniak, M.A., Oldfield, E.(2008). Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3′-azido, 3′-deoxythymidine: A QSAR investigation . Bioorganic and Medicinal Chemistry. 16. (19). p. 8959-8967.
Chan, J.M.W., Swager, T.M.(2008). Synthesis of arylethynylated cyclohexa-m-phenylenes via sixfold Suzuki coupling . Tetrahedron Letters. 49. (33). p. 4912-4914.
Hudock, M.P., Sanz-Rodríguez, C.E., Song, Y., Chan, J.M.W., Zhang, Y., Odeh, S., Kosztowski, T., Leon-Rossell, A., Concepción, J.L., Yardley, V., et al.(2006). Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates . Journal of Medicinal Chemistry. 49. (1). p. 215-223.
Kotsikorou, E., Song, Y., Chan, J.M.W., Faelens, S., Tovian, Z., Broderick, E., Bakalara, N., Docampo, R., Oldfield, E.(2005). Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase . Journal of Medicinal Chemistry. 48. (19). p. 6128-6139.
Ling, Y., Sahota, G., Odeh, S., Chan, J.M.W., Araujo, F.G., Moreno, S.N.J., Oldfield, E.(2005). Bisphosphonate inhibitors of Toxoplasma gondi growth: In vitro, QSAR, and in vivo investigations . Journal of Medicinal Chemistry. 48. (9). p. 3130-3140.
Sanders, J.M., Song, Y., Chan, J.M.W., Zhang, Y., Jennings, S., Kosztowski, T., Odeh, S., Flessner, R., Schwerdtfeger, C., Kotsikorou, E., et al.(2005). Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption . Journal of Medicinal Chemistry. 48. (8). p. 2957-2963.
Sanders, J.M., Ghosh, S., Chan, J.M.W., Meints, G., Wang, H., Raker, A.M., Song, Y., Colantino, A., Burzynska, A., Kafarski, P., et al.(2004). Quantitative Structure-Activity Relationships for γδ T Cell Activation by Bisphosphonates . Journal of Medicinal Chemistry. 47. (2). p. 375-384.
Ghosh, S., Chan, J.M.W., Lea, C.R., Meints, G.A., Lewis, J.C., Tovian, Z.S., Flessner, R.M., Loftus, T.C., Bruchhaus, I., Kendrick, H., et al.(2004). Effects of Bisphosphonates on the Growth of Entamoeba histolytica and Plasmodium Species in Vitro and in Vivo . Journal of Medicinal Chemistry. 47. (1). p. 175-187.
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