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Profile Details
Subject Matter Expertise
Services
Writing
Technical Writing,
Newswriting
Data & AI
Statistical Analysis,
Data Visualization
Product Development
Stability/Shelf Life Testing
Work Experience
Founder
Nanoceuticals
January 2018 - Present
Professor
University of Brasília
March 2012 - Present 
Education
PhD (Genetics and Morphology)
University of Brasília
January 2008 - December 2011
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
(2018). Synthesis and Evaluation of New Potential Benzo[<i>a</i>]phenoxazinium Photosensitizers for Anticancer Photodynamic Therapy . Molecules.
Ganassin, Rayane, Souza, Ludmilla Regina de, Py-Daniel, Karen Rapp, Longo, João Paulo Figueiró, Coelho, Janaína Moreira, Rodrigues, Mosar Correa, Jiang, Cheng-Shi, Gu, Jinsong, Morais, Paulo César de, Mosiniewicz-Szablewska, Ewa(2018). Decoration of a Poly (methyl vinyl ether-co-maleic anhydride)-Shelled Selol Nanocapsule with Folic Acid Increases Its Activity Against Different Cancer Cell Lines In Vitro. Journal of Nanoscience and Nanotechnology. 18. (1). p. 522-528.
Camara, A. L. D., Nagel, G., Tschiche, H. R., Cardador, C. M., Muehlmann, L. A., de Oliveira, D. M., Alvim, P. Q., Azevedo, R. B., Calderon, M., Longo, J. P. F.(2017). Acid-sensitive lipidated doxorubicin prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model . Nanomedicine. 12. (15). p. 1751-1765.
dos Santos Câmara, Ana Lygia, Nagel, Gregor, Tschiche, Harald R, Cardador, Camila Magalhães, Muehlmann, Luis Alexandre, de Oliveira, Daniela Mara, Alvim, Paula Queiroz, Azevedo, Ricardo Bentes, Calderón, Marcelo, Figueiró Longo, João Paulo(2017). Acid-sensitive lipidated doxorubicin prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model. Nanomedicine. 12. (15). p. 1751-1765.
Zhang, Juan, Jiang, Chengshi, Longo, João Paulo Figueiró, Azevedo, Ricardo Bentes, Zhang, Hua, Muehlmann, Luis Alexandre(2017). An updated overview on the development of new photosensitizers for anticancer photodynamic therapy. Acta Pharmaceutica Sinica B.
Song, Jia-Li, Zhang, Juan, Liu, Chang-Liang, Liu, Chao, Zhu, Kong-Kai, Yang, Fei-Fei, Liu, Xi-Gong, Longo, João Paulo Figueiró, Muehlmann, Luis Alexandre, Azevedo, Ricardo Bentes(2017). Design and synthesis of pregnenolone/2-cyanoacryloyl conjugates with dual NF-κB inhibitory and anti-proliferative activities. Bioorganic & medicinal chemistry letters. 27. (20). p. 4682-4686.
Coelho, B. C. P., Siqueira, E. R., Ombredane, A. S., Joanitti, G. A., Chaves, S. B., da Silva, S. W., Chaker, J. A., Longo, J. P. F., Azevedo, R. B., Morais, P. C., et al.(2017). Maghemite-gold core-shell nanostructures (gamma-Fe2O3@Au) surface-functionalized with aluminium phthalocyanine for multi-task imaging and therapy . Rsc Advances. 7. (19). p. 11223-11232.
Longo, João Paulo Figueiró, Valois, Caroline Alves, Tapajós, Érica Correio Coelho, Santos, Maria de Fátima Menezes Almeida, de Azevedo, Ricardo Bentes(2017). Cytotoxicity and genotoxicity of endodontic irrigants on human cells. Archives of Oral Research. 6. (2).
Bonadio, Raphael S, Arcanjo, Ana Carolina, Lima, Emilia CD, Vasconcelos, Alline T, Silva, Renata C, Horst, Frederico H, Azevedo, Ricardo B, Poças-Fonseca, Marcio José, F Longo, João Paulo(2017). DNA methylation alterations induced by transient exposure of MCF-7 cells to maghemite nanoparticles. Nanomedicine. 12. (23). p. 2637-2649.
Joanitti, G. A., Ganassin, R., Rodrigues, M. C., Longo, J. P., Jiang, C. S., Gu, J. S., Pinto, S. M. L., dos Santos, Mdma, de Azevedo, R. B., Muehlmann, L. A.(2017). Nanostructured Systems for the Organelle-specific Delivery of Anticancer Drugs . Mini-Reviews in Medicinal Chemistry. 17. (3). p. 224-236.
Silva-Vinhote, N, elly Mara, Caballero, Nelson Eduardo Dur, an, de Amorim Silva, Taciana, Quelemes, Patrick Veras, de Ara, ujo, Alyne Rodrigues, de Moraes, Ana Carolina Mazarin, dos Santos Câmara, Ana Lygia, et al.(2017). Extracellular biogenic synthesis of silver nanoparticles by Actinomycetes from amazonic biome and its antimicrobial efficiency. African Journal of Biotechnology. 16. (43). p. 2072-2082.
Anselmo Joanitti, Graziella, Ganassin, Rayane, Correa Rodrigues, Mosar, Paulo Figueiro Longo, Joao, Jiang, Cheng-Shi, Gu, Jinsong, Milena Leal Pinto, Sandra, de Fatima, Menezes Almeida dos Santos, Bentes de Azevedo, Ricardo, Alexandre Muehlmann, Luis(2017). Nanostructured Systems for the Organelle-specific Delivery of Anticancer Drugs. Mini reviews in medicinal chemistry. 17. (3). p. 224-236.
Ganassin, Rayane, Merker, Carolin, Rodrigues, Mosar Corrêa, Guimarães, Nayara Felipe, Sodré, Carine Sampaio Cerqueira, Ferreira, Queila da Silva, da Silva, Sebastião William, Ombredane, Alicia Simalie, Joanitti, Graziella Anselmo, Py-Daniel, Karen Rapp(2017). Nanocapsules for the co-delivery of selol and doxorubicin to breast adenocarcinoma 4T1 cells in vitro. Artificial cells, nanomedicine, and biotechnology. p. 1-11.
Monge-Fuentes, Victoria, Muehlmann, Luis Alexandre, Longo, João Paulo Figueiró, Silva, Jaqueline Rodrigues, Fascineli, Maria Luiza, de Souza, Paulo, Faria, Fernando, Degterev, Igor Anatolievich, Rodriguez, Anselmo, Carneiro, Fabiana Pirani(2017). Photodynamic therapy mediated by acai oil (Euterpe oleracea Martius) in nanoemulsion: A potential treatment for melanoma. Journal of Photochemistry and Photobiology B: Biology. 166. p. 301-310.
Morgado, L. F., Travolo, A. R. F., Muehlmann, L. A., Narcizo, P. S., Nunes, R. B., Pereira, P. A. G., Py-Daniel, K. R., Jiang, C. S., Gu, J. S., Azevedo, R. B., et al.(2017). Photodynamic Therapy treatment of onychomycosis with Aluminium-Phthalocyanine Chloride nanoemulsions: A proof of concept clinical trial . Journal of Photochemistry and Photobiology B-Biology. 173. p. 266-270.
Morgado, Luciano Ferreira, Trávolo, Ana Regina Franchi, Muehlmann, Luís Alexandre, Narcizo, Paulo Souza, Nunes, Rodrigo Barbosa, Pereira, Pedro Alencar Gomes, Daniel, Karen Py, Jiang, Cheng-Shi, Gu, Jinsong, Azevedo, Ricardo Bentes(2017). Photodynamic Therapy treatment of onychomycosis with Aluminium-Phthalocyanine Chloride nanoemulsions: A proof of concept clinical trial. Journal of Photochemistry and Photobiology B: Biology.
de Moraes, M., Vasconcelos, R. C., Longo, J. P. F., Muehlmann, L. A., de Azevedo, R. B., de Araujo, R. F., Araujo, A. A., Costa, A. D. L.(2017). Photodynamic therapy using chloro-aluminum phthalocyanine decreases inflammatory response in an experimental rat periodontal disease model . Journal of Photochemistry and Photobiology B-Biology. 167. p. 208-215.
de Moraes, Maiara, Vasconcelos, Roseane Carvalho, Longo, João Paulo Figueiró, Muehlmann, Luis Alexandre, de Azevedo, Ricardo Bentes, de Araújo Júnior, Raimundo Fernandes, Araujo, Aurigena Antunes, Costa, Antonio de Lisboa Lopes(2017). Photodynamic therapy using chloro-aluminum phthalocyanine decreases inflammatory response in an experimental rat periodontal disease model. Journal of Photochemistry and Photobiology B: Biology. 167. p. 208-215.
Veloso, A. B., Longo, J. P. F., Muehlmann, L. A., Tollstadius, B. F., Souza, P. E. N., Azevedo, R. B., Morais, P. C., Silva, S. W.(2017). SERS Investigation of Cancer Cells Treated with PDT: Quantification of Cell Survival and Follow-up . Scientific Reports. 7.
Monge-Fuentes, V., Muehlmann, L. A., Longo, J. P. F., Silva, J. R., Fascineli, M. L., de Souza, P., Faria, F., Degterev, I. A., Rodriguez, A., Carneiro, F. P., et al.(2017). Photodynamic therapy mediated by acai oil (Euterpe oleracea Martius) in nanoemulsion: A potential treatment for melanoma . Journal of Photochemistry and Photobiology B-Biology. 166. p. 301-310.
Coelho, BCP, Siqueira, ER, Ombredane, AS, Joanitti, GA, Chaves, SB, da Silva, SW, Chaker, JA, Longo, JPF, Azevedo, RB, Morais, PC(2017). Maghemite–gold core–shell nanostructures (γ-Fe 2 O 3@ Au) surface-functionalized with aluminium phthalocyanine for multi-task imaging and therapy. RSC Advances. 7. (19). p. 11223-11232.
Milhomem-Paixão, Susana Suely Rodrigues, Fascineli, Maria Luiza, Roll, Mariana Matos, Longo, João Paulo Figueiró, Azevedo, Ricardo Bentes, Pieczarka, Julio Cesar, Salgado, Hugo Leonardo Crisóstomo, Santos, Alberdan Silva, Grisolia, Cesar Koppe(2016). The lipidome, genotoxicity, hematotoxicity and antioxidant properties of andiroba oil from the Brazilian Amazon. Genetics and molecular biology. 39. (2). p. 248-256.
Longo, J. P. F., MuehInnann, L. A., Miranda-Vilela, A. L., Portilho, F. A., de Souza, L. R., Silva, J. R., Lacava, Z. G. M., Bocca, A. L., Chaves, S. B., Azevedo, R. B.(2016). Prevention of Distant Lung Metastasis After Photodynamic Therapy Application in a Breast Cancer Tumor Model . Journal of Biomedical Nanotechnology. 12. (4). p. 689-699.
Longo, João Paulo Figueiró, Muehlmann, Luis Alexandre, Miranda-Vilela, Ana Luisa, Portilho, Flávia Arruda, de Souza, Ludmilla Regina, Silva, Jaqueline Rodrigues, Lacava, Zulmira Guerrero Marques, Bocca, Anamelia Lorenzetti, Chaves, Sacha Braun, Azevedo, Ricardo Bentes(2016). Prevention of Distant Lung Metastasis After Photodynamic Therapy Application in a Breast Cancer Tumor Model. Journal of biomedical nanotechnology. 12. (4). p. 689-699.
Milhomem-Paixao, S. S. R., Fascineli, M. L., Roll, M. M., Longo, J. P. F., Azevedo, R. B., Pieczarka, J. C., Salgado, H. L. C., Santos, A. S., Grisolia, C. K.(2016). The lipidome, genotoxicity, hematotoxicity and antioxidant properties of andiroba oil from the Brazilian Amazon . Genetics and Molecular Biology. 39. (2). p. 248-256.
Li, J. C., Zhang, J., Rodrigues, M. C., Ding, D. J., Longo, J. P. F., Azevedo, R. B., Muehlmann, L. A., Jiang, C. S.(2016). Synthesis and evaluation of novel 1,2,3-triazole-based acetylcholinesterase inhibitors with neuroprotective activity . Bioorganic & Medicinal Chemistry Letters. 26. (16). p. 3881-3885.
Li, Jia-Cheng, Zhang, Juan, Rodrigues, Mosar Corrêa, Ding, De-Jun, Longo, João Paulo Figueiró, Azevedo, Ricardo Bentes, Muehlmann, Luis Alexandre, Jiang, Cheng-Shi(2016). Synthesis and evaluation of novel 1, 2, 3-triazole-based acetylcholinesterase inhibitors with neuroprotective activity. Bioorganic & medicinal chemistry letters. 26. (16). p. 3881-3885.
Marani, M. M., Dourado, F. S., Quelemes, P. V., de Araujo, A. R., Perfeito, M. L. G., Barbosa, E. A., Veras, L. M. C., Coelho, A. L. R., Andrade, E. B., Eaton, P., et al.(2015). Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus . Journal of Natural Products. 78. (7). p. 1495-1504.
Longo, J, Muehlmann, L, Almeida-Santos, M, Azevedo, R(2015). Preventing metastasis by targeting lymphatic vessels with photodynamic therapy based on nanostructured photosensitizers. J Nanomed Nanotechnol. 5. (1).
de Moraes, Maiara, de Vasconcelos, Roseane Carvalho, Longo, João Paulo Figueiró, Muehlmann, Luis Alexandre, de Azevedo, Ricardo Bentes, Lemos, Telma Maria Araújo Moura, Costa, Antonio de Lisboa Lopes(2015). Effects of photodynamic therapy mediated by nanoemulsion containing chloro-aluminum phthalocyanine: a histologic and immunohistochemical study in human gingiva. Photodiagnosis and photodynamic therapy. 12. (4). p. 592-597.
Rodrigues, Mosar C, Muehlmann, Luis A, Longo, João PF, Silva, Renata C, Graebner, Ilmar B, Degterev, Igor A, Lucci, Carolina M, Azevedo, Ricardo B, Garcia, Mônica P(2015). Photodynamic therapy based on Arrabidaea chica (Crajiru) extract nanoemulsion: in vitro activity against monolayers and spheroids of human mammary adenocarcinoma MCF-7 cells. Journal of Nanomedicine & Nanotechnology. 6. (3). p. 1.
de Moraes, M., Vasconcelos, R. C., Longo, J. P. F., Muehlmann, L. A., de Azevedo, R. B., Lemos, Tmam, Costa, A. D. L.(2015). Effects of photodynamic therapy mediated by nanoemulsion containing chloro-aluminum phthalocyanine: a histologic and immunohistochemical study in human gingiva . Photodiagnosis and Photodynamic Therapy. 12. (4). p. 592-597.
Muehlmann, L. A., Rodrigues, M. C., Longo, J. P. F., Garcia, M. P., Py-Daniel, K. R., Veloso, A. B., de Souza, P. E. N., da Silva, S. W., Azevedo, R. B.(2015). Aluminium-phthalocyanine chloride nanoemulsions for anticancer photodynamic therapy: Development and in vitro activity against monolayers and spheroids of human mammary adenocarcinoma MCF-7 cells . Journal of Nanobiotechnology. 13.
Muehlmann, Luis Alexandre, Rodrigues, Mosar Corrêa, Longo, João Paulo Figueiró, Garcia, Mônica Pereira, Py-Daniel, Karen Rapp, Veloso, Aline Bessa, de Souza, Paulo Eduardo Narciso, da Silva, Sebastião William, Azevedo, Ricardo Bentes(2015). Aluminium-phthalocyanine chloride nanoemulsions for anticancer photodynamic therapy: Development and in vitro activity against monolayers and spheroids of human mammary adenocarcinoma MCF-7 cells. Journal of nanobiotechnology. 13. (1). p. 36.
Miranda-Vilela, A. L., Grisolia, C. K., Longo, J. P. F., Peixoto, R. C. A., de Almeida, M. C., Barbosa, L. C. P., Roll, M. M., Portilho, F. A., Estevanato, L. L. C., Bocca, A. L., et al.(2014). Oil rich in carotenoids instead of vitamins C and E as a better option to reduce doxorubicin-induced damage to normal cells of Ehrlich tumor-bearing mice: hematological, toxicological and histopathological evaluations . Journal of Nutritional Biochemistry. 25. (11). p. 1161-1176.
Muehlmann, L. A., Ma, B. C., Longo, J. P. F., Menezes, M. D., Santos, A., Azevedo, R. B.(2014). A luminum-phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy . International Journal of Nanomedicine. 9. p. 1199-1213.
Miranda-Vilela, A. L., Yamamoto, K. R., Miranda, K. L. C., Matos, B. N., de Almeida, M. C., Longo, J. P. F., de Souza, J., Fernandes, J. M. S., Sartoratto, P. P. C., Lacava, Z. G. M.(2014). Dextran-functionalized magnetic fluid mediating magnetohyperthermia for treatment of Ehrlich-solid-tumor-bearing mice: toxicological and histopathological evaluations . Tumor Biology. 35. (4). p. 3391-3403.
Miranda-Vilela, A. L., Peixoto, R. C. A., Longo, J. P. F., Cintra, Ddse, Portilho, F. A., Miranda, K. L. C., Sartoratto, P. P. C., Bao, S. N., de Azevedo, R. B., Lacava, Z. G. M.(2013). Dextran-Functionalized Magnetic Fluid Mediating Magnetohyperthermia Combined with Preventive Antioxidant Pequi-Oil Supplementation: Potential Use Against Cancer . Journal of Biomedical Nanotechnology. 9. (7). p. 1261-1271.
Longo, J. P. F., de Melo, L. N. D., Mijan, M. C., Valois, C. R. A., Joanitti, G. A., Simioni, A. R., Tedesco, A. C., de Azevedo, R. B.(2013). Photodynamic Therapy Mediated by Liposomal Chloroaluminum-Phthalocyanine Induces Necrosis in Oral Cancer Cells . Journal of Biomaterials and Tissue Engineering. 3. (1). p. 148-156.
Bicalho, L. S., Longo, J. P., Cavalcantil, C. E. O., Simioni, A. R., Bocca, A. L., Santos, Mdmd, Tedesco, A. C., Azevedo, R. B.(2013). Photodynamic Therapy Leads to Complete Remission of Tongue Tumors and Inhibits Metastases to Regional Lymph Nodes . Journal of Biomedical Nanotechnology. 9. (5). p. 811-818.
Portilho, F. A., Cavalcanti, C. E. D., Miranda-Vilela, A. L., Estevanato, L. L. C., Longo, J. P. F., Santos, Mdma, Bocca, A. L., Martins, O. P., Simioni, A. R., Morais, P. C., et al.(2013). Antitumor activity of photodynamic therapy performed with nanospheres containing zinc-phthalocyanine . Journal of Nanobiotechnology. 11.
Rocha, M. S. T., Lucci, C. M., Longo, J. P. F., Galera, P. D., Simioni, A. R., Lacava, Z. G. M., Tedesco, A. C., Azevedo, R. B.(2012). Aluminum-Chloride-Phthalocyanine Encapsulated in Liposomes: Activity Against Naturally Occurring Dog Breast Cancer Cells . Journal of Biomedical Nanotechnology. 8. (2). p. 251-257.
Pereira, L. O., Longo, J. P. F., Azevedo, R. B.(2012). Laser irradiation did not increase the proliferation or the differentiation of stem cells from normal and inflamed dental pulp . Archives of Oral Biology. 57. (8). p. 1079-1085.
Longo, J. P. F., Leal, S. C., Simioni, A. R., Almeida-Santos, M. D. M., Tedesco, A. C., Azevedo, R. B.(2012). Photodynamic therapy disinfection of carious tissue mediated by aluminum-chloride-phthalocyanine entrapped in cationic liposomes: an in vitro and clinical study . Lasers in Medical Science. 27. (3). p. 575-584.
Amador, R. R., Longo, J. P. F., Lacava, Z. G., Dorea, J. G., Santos, Mdma(2012). Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells . Genetics and Molecular Biology. 35. (1). p. 153-158.
Muehlmann, L. A., Joanitti, G. A., Silva, J. R., Longo, J. P. F., Azevedo, R. B.(2011). Liposomal photosensitizers: potential platforms for anticancer photodynamic therapy . Brazilian Journal of Medical and Biological Research. 44. (8). p. 729-737.
Longo, J. P. F., Lozzi, S. P., Simioni, A. R., Morais, P. C., Tedesco, A. C., Azevedo, R. B.(2009). Photodynamic therapy with aluminum-chloro-phtalocyanine induces necrosis and vascular damage in mice tongue tumors . Journal of Photochemistry and Photobiology B-Biology. 94. (2). p. 143-146.
Tapajos, E. C. C., Longo, J. P., Simioni, A. R., Lacava, Z. G. M., Santos, Mfma, Morais, P. C., Tedesco, A. C., Azevedo, R. B.(2008). In vitro photodynamic therapy on human oral keratinocytes using chloroaluminum-phthalocyanine . Oral Oncology. 44. (11). p. 1073-1079.
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