Profile Details

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Hire Dr. Jak G.

United Kingdom

PhD Biophysicist | Expert in Receptor Pharmacology & Advanced Microscopy

Profile Summary

PhD student with a Masters degree in Immunology and job experience in multiple settings (GSK, Francis Crick, Academia). I have multiple first-author papers, reviews and book chapters. Industrial experience at a top-pharmaceutical company and expertise with wet lab work (cell-based assays, single-molecule microscopy, receptor pharmacology, GPCRs, molecular biology). Extensive experience with scientific writing, manuscript and figure preparation; with the ability to create succinct and professional documents. Fun fact: I've a keen interest in science-fiction and love to hypothesise and posit new ideas which may be possible in the future, backed up by strong science. I'm also an avid cook with classical training - which I like fusing with my scientific know-how!

Subject Matter Expertise

• ★ Microscopy
• ☆ Matlab
• ☆ Allergy & Clinical Immunology

Services

• Writing
• Research
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Technical Writing, Newswriting

Research Market Research, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis, Data Visualization

Product Development Formulation

Work Experience

PhD Biophysics

University of Birmingham

September 2018 - Present

MSc Research Student

Francis Crick Institute

August 2017 - July 2018

Industrial Placement - 12 months

GlaxoSmithkline

September 2015 - September 2016

Education

PhD Biophysics - Single-molecule microscopy study of G-protein coupled receptors

University of Birmingham

September 2018 - Present

MSc Immunology (Funded by Asthma UK - awarded Immunology prize for Research)

Imperial College London & King's College London

August 2017 - July 2018

BSc Biological Sciences (1st class honours & awarded School Prize for Biology)

Aston University

September 2013 - June 2017

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Grimes J, Desai S, Charter NW, Lodge J, Moita Santos R, Isidro-Llobet A, Mason AM, Wu Z, Wolfe LA, Anantharaman L, et al.(2019). MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions . Pharmacology research & perspectives.

(2019). The mast cell receptor MrgX2 and drug-induced anaphylaxis . Journal of pharmacological and toxicological methods.

Calebiro D, Grimes J(2019). G Protein-Coupled Receptor Pharmacology at the Single-Molecule Level . Annual review of pharmacology and toxicology.

Buenaventura T, Bitsi S, Laughlin WE, Burgoyne T, Lyu Z, Oqua AI, Norman H, McGlone ER, Klymchenko AS, Corrêa IR, et al.(2019). Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells . PLoS biology.