Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 30 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Gyan Prakash M.

India

USD 30 /hr

Freelance Bioinformatician & Data Analyst

Profile Summary

I am a computational biologist with experience in quantitative, statistical and integrative analysis of various omics datasets such as bulk-RNAseq, scRNAseq, ChIP-seq, CUT&RUN, CUT&TAG, BSseq, RNA-pol-II ChIPseq. I have worked on several projects during my PhD and postdoctoral traning where I studied epigenetic regulation of gene expression. I am proficient in using R, Python, Shell scripting and using high performance computing cluster (e.g SGE, SLRUM).

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Omics
• ☆ Transcriptomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ RNA Sequencing
• ☆ ChIP-Seq
• ☆ Data Analysis
• ☆ Bioinformatics
• ☆ Systems Biology
• ☆ Python
• ☆ R

Services

• Data & AI

Data & AI Predictive Modeling, Statistical Analysis, Data Visualization, Big Data Analytics, Data Mining, Data Cleaning, Data Processing

Work Experience

PostdoctoralResearcher

UTSouthwestern Medical Center

June 2023 - Present

PhD student

Institute of Life Sciences

July 2015 - Present

Education

M.S.(Pharm) (Pharmacoinformatics)

National Institute of Pharmaceutical Education and Research

August 2013 - June 2015

B.Pharm (Manipal College of Pharmaceutical Sciences)

Manipal University

June 2009 - May 2013

Certifications

• Bioinformatics National Certification

  Department of Biotechnology, Government of India

  August 2017 - Present

Publications

JOURNAL ARTICLE

Gyan Prakash Mishra (2022). Epigenomics of conventional type-I dendritic cells depicted preferential control of TLR9 versus TLR3 response by NCoR1 through differential IRF3 activation . Cellular and molecular life sciences : CMLS.

(2022). Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes . Nucleic Acids Research. 50. (3). p. 1551--1561. Oxford University Press (OUP)

Pathak, A.K., Mishra, G.P., Uppili, B., Walia, S., Fatihi, S., Abbas, T., Banu, S., Ghosh, A., Kanampalliwar, A., Jha, A., et al.(2022). Spatio-Temporal dynamics of intra-host variability in SARS-CoV-2 genomes . Nucleic Acids Research. 50. (3). p. 1551-1561.

(2020). NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9 . European journal of immunology.

Gyan Prakash Mishra, Debojyoti Das, Aniruddha Das, Mousumi Sahu, Smruti Sambhav Mishra, Shaheerah Khan, Pruthvi R. Bejugam, Pranita K. Rout, Arundhati Das, Shehnaz Bano, et al.(2020). Identification and Characterization of Circular Intronic RNAs Derived from Insulin Gene . International Journal of Molecular Sciences. 21. (12). p. 4302. {MDPI} {AG}

(2020). BedSect: An Integrated Web Server Application to Perform Intersection, Visualization, and Functional Annotation of Genomic Regions From Multiple Datasets . Frontiers in genetics.

Das, D., Das, A., Sahu, M., Mishra, S.S., Khan, S., Bejugam, P.R., Rout, P.K., Das, A., Bano, S., Mishra, G.P., et al.(2020). Identification and characterization of circular intronic RNAs derived from insulin gene . International Journal of Molecular Sciences. 21. (12). p. 1-17.

Mishra, G.P., Ghosh, A., Jha, A., Raghav, S.K.(2020). BedSect: An Integrated Web Server Application to Perform Intersection, Visualization, and Functional Annotation of Genomic Regions From Multiple Datasets . Frontiers in Genetics. 11.

Ahad, A., Smita, S., Mishra, G.P., Biswas, V.K., Sen, K., Gupta, B., Garcin, D., Acha-Orbea, H., Raghav, S.K.(2020). NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9 . European Journal of Immunology. 50. (12). p. 1959-1975.

(2019). NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance . iScience.

Ahad, A., Stevanin, M., Smita, S., Mishra, G.P., Gupta, D., Waszak, S., Sarkar, U.A., Basak, S., Gupta, B., Acha-Orbea, H., et al.(2019). NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance . iScience. 19. p. 996-1011.

Panda, A., Sen, D., Ghosh, A., Gupta, A., Malar C., M., Mishra, G.P., Singh, D., Ye, W., Tyler, B.M., Tripathy, S.(2018). EumicrobeDBLite: A lightweight genomic resource and analytic platform for draft oomycete genomes . Molecular Plant Pathology. 19. (1). p. 227-237.

(2017). EumicrobeDBLite: a lightweight genomic resource and analytic platform for draft oomycete genomes . Molecular Plant Pathology.

Sen, D., Chandrababunaidu, M.M., Singh, D., Sanghi, N., Ghorai, A., Mishra, G.P., Madduluri, M., Adhikary, S.P., Tripathy, S.(2016). Draft genome sequence of the terrestrial cyanobacterium Scytonema millei VB511283, isolated from eastern India . Genome Announcements. 3. (2).

Das, A., Panda, A., Singh, D., Chandrababunaidu, M.M., Mishra, G.P., Bhan, S., Adhikary, S.P., Tripathy, S.(2016). Deciphering the genome sequences of the hydrophobic cyanobacterium Scytonema tolypothrichoides VB-61278 . Genome Announcements. 3. (2).

(2015). Deciphering the Genome Sequences of the Hydrophobic Cyanobacterium Scytonema tolypothrichoides VB-61278 . Genome announcements.

(2015). Draft Genome Sequence of the Terrestrial Cyanobacterium Scytonema millei VB511283, Isolated from Eastern India . Genome announcements.

PREPRINT

Gyan Prakash Mishra, Atimukta Jha, Abdul Ahad, Kaushik Sen, Shuchi Smita, Aliva P Minz, Viplov Kumar Biswas, Archana Tripathy, Shanti Bhushan Senapati, Bhawna Gupta, et al. (2021). NCoR1 and SMRT fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling .

OTHER

Jha, A., Ahad, A., Mishra, G.P., Sen, K., Smita, S., Minz, A.P., Biswas, V.K., Tripathy, A., Senapati, S.B., Gupta, B., et al.(2021). NCoR1 and SMRT fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling . bioRxiv.

Gyan Prakash Mishra, Ankit K. Pathak, Bharathram Uppili, Safal Walia, Saman Fatihi, Tahseen Abbas, Sofia Banu, Arup Ghosh, Amol Kanampalliwar, Atimukta Jha, et al.(2020). Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes . Cold Spring Harbor Laboratory

Pathak, A.K., Mishra, G.P., Uppili, B., Walia, S., Fatihi, S., Abbas, T., Banu, S., Ghosh, A., Kanampalliwar, A., Jha, A., et al.(2020). Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes . bioRxiv.