Hire Dr. Giulio Preta
Proteins & Peptides Expert

Summary

I'm interested in several aspects of the cell biology, including the molecular mechanisms of cellular responses to different types of stress (pore forming toxins, cytotoxic drugs, irradiation). Moreover, I am interested in the biophysics of lipid rafts and in the identification of new factors capable to disrupt these membrane domains. The importance of investigating the intrinsic nature of lipid rafts is underlined by their involvement in many processes including bacterial and viral entry.

Subject Matter Expertise

• Proteins & Peptides
• Biochemistry
• Biology
• Antioxidants & Oxidative Stress
• Immunology
• Colorectal Cancer
• Antigens
• Reproductive Immunology

Services

• Literature search
• Scientific consulting
• Experiment design
• Writing

Work Experience

• Research officer

  Swansea University

  March 2013 - June 2016

• Post Doctoral Fellow

  Karolinska Institute

  January 2008 - August 2012

Education

• PhD in Experimental Oncology

  University of Ferrara

  August 2003 - June 2006

• Veterinary Medicine

  University of Bologna

  August 1997 - June 2002

Publications

JOURNAL ARTICLE
• {"ProfilePublicationId":17295,"Type":"journal-article","Citation":"Preta G, Jankunec M, Heinrich F, Griffin S, Sheldon IM, Valincius G, Biochimica et biophysica acta, 2016, vol. 1858, no. 9, pp. 2070-2080, 2016","JournalTitle":"","Title":"Tethered bilayer membranes as a complementary tool for functional and structural studies: The pyolysin case.","CitationType":"formatted-unspecified","DOI":"10.1016/j.bbamem.2016.05.016","Date":"2016-09-00","Url":"http://europepmc.org/abstract/med/27211243","PublicationContributors":[{"PublicationContributorId":68384,"ProfilePublicationId":17295,"ContributorName":"Valincius G","CountributorRole":"author"},{"PublicationContributorId":68383,"ProfilePublicationId":17295,"ContributorName":"Sheldon IM","CountributorRole":"author"},{"PublicationContributorId":68382,"ProfilePublicationId":17295,"ContributorName":"Griffin S","CountributorRole":"author"},{"PublicationContributorId":68381,"ProfilePublicationId":17295,"ContributorName":"Heinrich F","CountributorRole":"author"},{"PublicationContributorId":68380,"ProfilePublicationId":17295,"ContributorName":"Jankunec M","CountributorRole":"author"},{"PublicationContributorId":68379,"ProfilePublicationId":17295,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17296,"Type":"journal-article","Citation":"Preta G, Cronin JG, Sheldon IM, Cell communication and signaling : CCS, 2015, vol. 13, pp. 24, 2015","JournalTitle":"","Title":"Dynasore - not just a dynamin inhibitor.","CitationType":"formatted-unspecified","DOI":"10.1186/s12964-015-0102-1","Date":"2015-04-00","Url":"http://europepmc.org/abstract/med/25889964","PublicationContributors":[{"PublicationContributorId":68387,"ProfilePublicationId":17296,"ContributorName":"Sheldon IM","CountributorRole":"author"},{"PublicationContributorId":68386,"ProfilePublicationId":17296,"ContributorName":"Cronin JG","CountributorRole":"author"},{"PublicationContributorId":68385,"ProfilePublicationId":17296,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17297,"Type":"journal-article","Citation":"Preta G, Lotti V, Cronin JG, Sheldon IM, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, vol. 29, no. 4, pp. 1516-1528, 2015","JournalTitle":"","Title":"Protective role of the dynamin inhibitor Dynasore against the cholesterol-dependent cytolysin of Trueperella pyogenes.","CitationType":"formatted-unspecified","DOI":"10.1096/fj.14-265207","Date":"2015-04-00","Url":"http://europepmc.org/abstract/med/25550455","PublicationContributors":[{"PublicationContributorId":68391,"ProfilePublicationId":17297,"ContributorName":"Sheldon IM","CountributorRole":"author"},{"PublicationContributorId":68390,"ProfilePublicationId":17297,"ContributorName":"Cronin JG","CountributorRole":"author"},{"PublicationContributorId":68389,"ProfilePublicationId":17297,"ContributorName":"Lotti V","CountributorRole":"author"},{"PublicationContributorId":68388,"ProfilePublicationId":17297,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17298,"Type":"journal-article","Citation":"Ottosson-Wadlund A, Ceder R, Preta G, Pokrovskaja K, Grafstr\u0026#246;m RC, Heyman M, S\u0026#246;derh\u0026#228;ll S, Grand\u0026#233;r D, Hedenfalk I, Robertson JD, Fadeel B, Molecular pharmacology, 2013, vol. 83, no. 1, pp. 245-255, 2013","JournalTitle":"","Title":"Requirement of apoptotic protease-activating factor-1 for bortezomib-induced apoptosis but not for Fas-mediated apoptosis in human leukemic cells.","CitationType":"formatted-unspecified","DOI":"10.1124/mol.112.080788","Date":"2013-01-00","Url":"http://europepmc.org/abstract/med/23093495","PublicationContributors":[{"PublicationContributorId":68402,"ProfilePublicationId":17298,"ContributorName":"Fadeel B","CountributorRole":"author"},{"PublicationContributorId":68401,"ProfilePublicationId":17298,"ContributorName":"Robertson JD","CountributorRole":"author"},{"PublicationContributorId":68400,"ProfilePublicationId":17298,"ContributorName":"Hedenfalk I","CountributorRole":"author"},{"PublicationContributorId":68399,"ProfilePublicationId":17298,"ContributorName":"Grand\u0026#233;r D","CountributorRole":"author"},{"PublicationContributorId":68398,"ProfilePublicationId":17298,"ContributorName":"S\u0026#246;derh\u0026#228;ll S","CountributorRole":"author"},{"PublicationContributorId":68397,"ProfilePublicationId":17298,"ContributorName":"Heyman M","CountributorRole":"author"},{"PublicationContributorId":68396,"ProfilePublicationId":17298,"ContributorName":"Grafstr\u0026#246;m RC","CountributorRole":"author"},{"PublicationContributorId":68395,"ProfilePublicationId":17298,"ContributorName":"Pokrovskaja K","CountributorRole":"author"},{"PublicationContributorId":68394,"ProfilePublicationId":17298,"ContributorName":"Preta G","CountributorRole":"author"},{"PublicationContributorId":68393,"ProfilePublicationId":17298,"ContributorName":"Ceder R","CountributorRole":"author"},{"PublicationContributorId":68392,"ProfilePublicationId":17298,"ContributorName":"Ottosson-Wadlund A","CountributorRole":"author"}]}
• {"ProfilePublicationId":17299,"Type":"journal-article","Citation":"Preta G, Fadeel B, FEBS letters, 2012, vol. 586, no. 6, pp. 747-752, 2012","JournalTitle":"","Title":"Scythe cleavage during Fas (APO-1)-and staurosporine-mediated apoptosis.","CitationType":"formatted-unspecified","DOI":"10.1016/j.febslet.2012.01.034","Date":"2012-03-00","Url":"http://europepmc.org/abstract/med/22285488","PublicationContributors":[{"PublicationContributorId":68404,"ProfilePublicationId":17299,"ContributorName":"Fadeel B","CountributorRole":"author"},{"PublicationContributorId":68403,"ProfilePublicationId":17299,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17300,"Type":"journal-article","Citation":"Preta G, Fadeel B, PloS one, 2012, vol. 7, no. 10, pp. e47328, 2012","JournalTitle":"","Title":"AIF and Scythe (Bat3) regulate phosphatidylserine exposure and macrophage clearance of cells undergoing Fas (APO-1)-mediated apoptosis.","CitationType":"formatted-unspecified","DOI":"10.1371/journal.pone.0047328","Date":"2012-00-00","Url":"http://europepmc.org/abstract/med/23077592","PublicationContributors":[{"PublicationContributorId":68406,"ProfilePublicationId":17300,"ContributorName":"Fadeel B","CountributorRole":"author"},{"PublicationContributorId":68405,"ProfilePublicationId":17300,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17301,"Type":"journal-article","Citation":"Hansson ML, Behmer S, Ceder R, Mohammadi S, Preta G, Grafstr\u0026#246;m RC, Fadeel B, Wallberg AE, PloS one, 2012, vol. 7, no. 9, pp. e46001, 2012","JournalTitle":"","Title":"MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer.","CitationType":"formatted-unspecified","DOI":"10.1371/journal.pone.0046001","Date":"2012-00-00","Url":"http://europepmc.org/abstract/med/23029358","PublicationContributors":[{"PublicationContributorId":68414,"ProfilePublicationId":17301,"ContributorName":"Wallberg AE","CountributorRole":"author"},{"PublicationContributorId":68413,"ProfilePublicationId":17301,"ContributorName":"Fadeel B","CountributorRole":"author"},{"PublicationContributorId":68412,"ProfilePublicationId":17301,"ContributorName":"Grafstr\u0026#246;m RC","CountributorRole":"author"},{"PublicationContributorId":68411,"ProfilePublicationId":17301,"ContributorName":"Preta G","CountributorRole":"author"},{"PublicationContributorId":68410,"ProfilePublicationId":17301,"ContributorName":"Mohammadi S","CountributorRole":"author"},{"PublicationContributorId":68409,"ProfilePublicationId":17301,"ContributorName":"Ceder R","CountributorRole":"author"},{"PublicationContributorId":68408,"ProfilePublicationId":17301,"ContributorName":"Behmer S","CountributorRole":"author"},{"PublicationContributorId":68407,"ProfilePublicationId":17301,"ContributorName":"Hansson ML","CountributorRole":"author"}]}
• {"ProfilePublicationId":17302,"Type":"journal-article","Citation":"Preta G, de Klark R, Chakraborti S, Glas R, Biochemical and biophysical research communications, 2010, vol. 399, no. 3, pp. 324-330, 2010","JournalTitle":"","Title":"MAP kinase-signaling controls nuclear translocation of tripeptidyl-peptidase II in response to DNA damage and oxidative stress.","CitationType":"formatted-unspecified","DOI":"10.1016/j.bbrc.2010.06.133","Date":"2010-08-00","Url":"http://europepmc.org/abstract/med/20643100","PublicationContributors":[{"PublicationContributorId":68418,"ProfilePublicationId":17302,"ContributorName":"Glas R","CountributorRole":"author"},{"PublicationContributorId":68417,"ProfilePublicationId":17302,"ContributorName":"Chakraborti S","CountributorRole":"author"},{"PublicationContributorId":68416,"ProfilePublicationId":17302,"ContributorName":"de Klark R","CountributorRole":"author"},{"PublicationContributorId":68415,"ProfilePublicationId":17302,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17303,"Type":"journal-article","Citation":"Preta G, de Klark R, Gavioli R, Glas R, Journal of oncology, 2010, vol. 2010, pp. 1313-1318, 2010","JournalTitle":"","Title":"The Enigma of Tripeptidyl-Peptidase II: Dual Roles in Housekeeping and Stress.","CitationType":"formatted-unspecified","DOI":"10.1155/2010/128478","Date":"2010-00-00","Url":"http://europepmc.org/abstract/med/20847939","PublicationContributors":[{"PublicationContributorId":68422,"ProfilePublicationId":17303,"ContributorName":"Glas R","CountributorRole":"author"},{"PublicationContributorId":68421,"ProfilePublicationId":17303,"ContributorName":"Gavioli R","CountributorRole":"author"},{"PublicationContributorId":68420,"ProfilePublicationId":17303,"ContributorName":"de Klark R","CountributorRole":"author"},{"PublicationContributorId":68419,"ProfilePublicationId":17303,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17304,"Type":"journal-article","Citation":"Preta G, de Klark R, Glas R, Biochemical and biophysical research communications, 2009, vol. 389, no. 4, pp. 575-579, 2009","JournalTitle":"","Title":"A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.","CitationType":"formatted-unspecified","DOI":"10.1016/j.bbrc.2009.09.021","Date":"2009-11-00","Url":"http://europepmc.org/abstract/med/19747897","PublicationContributors":[{"PublicationContributorId":68425,"ProfilePublicationId":17304,"ContributorName":"Glas R","CountributorRole":"author"},{"PublicationContributorId":68424,"ProfilePublicationId":17304,"ContributorName":"de Klark R","CountributorRole":"author"},{"PublicationContributorId":68423,"ProfilePublicationId":17304,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17305,"Type":"journal-article","Citation":"Preta G, Marescotti D, Fortini C, Carcoforo P, Castelli C, Masucci M, Gavioli R, Scandinavian journal of immunology, 2008, vol. 68, no. 6, pp. 579-588, 2008","JournalTitle":"","Title":"Inhibition of serine-peptidase activity enhances the generation of a survivin-derived HLA-A2-presented CTL epitope in colon-carcinoma cells.","CitationType":"formatted-unspecified","DOI":"10.1111/j.1365-3083.2008.02175.x","Date":"2008-12-00","Url":"http://europepmc.org/abstract/med/19000094","PublicationContributors":[{"PublicationContributorId":68432,"ProfilePublicationId":17305,"ContributorName":"Gavioli R","CountributorRole":"author"},{"PublicationContributorId":68431,"ProfilePublicationId":17305,"ContributorName":"Masucci M","CountributorRole":"author"},{"PublicationContributorId":68430,"ProfilePublicationId":17305,"ContributorName":"Castelli C","CountributorRole":"author"},{"PublicationContributorId":68429,"ProfilePublicationId":17305,"ContributorName":"Carcoforo P","CountributorRole":"author"},{"PublicationContributorId":68428,"ProfilePublicationId":17305,"ContributorName":"Fortini C","CountributorRole":"author"},{"PublicationContributorId":68427,"ProfilePublicationId":17305,"ContributorName":"Marescotti D","CountributorRole":"author"},{"PublicationContributorId":68426,"ProfilePublicationId":17305,"ContributorName":"Preta G","CountributorRole":"author"}]}
• {"ProfilePublicationId":17306,"Type":"journal-article","Citation":"Hoeflich A, Fettscher O, Preta G, Lahm H, Kolb HJ, Wolf E, Weber MM, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, vol. 35, no. 11-12, pp. 816-821, 2003","JournalTitle":"","Title":"Increased activity of catalase in tumor cells overexpressing IGFBP-2.","CitationType":"formatted-unspecified","DOI":"","Date":"2003-00-00","Url":"http://europepmc.org/abstract/med/14710363","PublicationContributors":[{"PublicationContributorId":68439,"ProfilePublicationId":17306,"ContributorName":"Weber MM","CountributorRole":"author"},{"PublicationContributorId":68438,"ProfilePublicationId":17306,"ContributorName":"Wolf E","CountributorRole":"author"},{"PublicationContributorId":68437,"ProfilePublicationId":17306,"ContributorName":"Kolb HJ","CountributorRole":"author"},{"PublicationContributorId":68436,"ProfilePublicationId":17306,"ContributorName":"Lahm H","CountributorRole":"author"},{"PublicationContributorId":68435,"ProfilePublicationId":17306,"ContributorName":"Preta G","CountributorRole":"author"},{"PublicationContributorId":68434,"ProfilePublicationId":17306,"ContributorName":"Fettscher O","CountributorRole":"author"},{"PublicationContributorId":68433,"ProfilePublicationId":17306,"ContributorName":"Hoeflich A","CountributorRole":"author"}]}