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Profile Details
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Hire Dr. Dora P.
United Kingdom
Profile Summary
Subject Matter Expertise
Services
Work Experience

Medical Advisor

Vifor Pharma UK Ltd

December 2018 - Present

Group Leader/ Principal Investigator

University of Cambridge

April 2016 - Present

Group Leader

University of Cambridge

April 2016 - November 2018

Senior Investigator Scientist

Medical Research Council

July 2014 - March 2016

Investigator Scientist

Medical Research Council

June 2005 - July 2014

Visiting post-doctoral fellow

Medical Research Council

February 2003 - May 2005

CIPAN SA

April 1997 - July 1999

Education

PhD (Food Biosciences)

University of Reading

October 1999 - August 2003

Biochemical Engineering (Chemical Engineering)

Instituto Superior Tecnico Centro de Quimica-Fisica Molecular

October 1991 - February 1997

Certifications
  • Certification details not provided.
Publications
OTHER
Pereira DI, Mohammed NI, Ofordile O, Camara F, Baldeh B, Mendy T, Sanyang C, Jallow AT, Hossain I, Wason J, et al.(2018). A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children: The IHAT-GUT double-blind, randomised, placebo-controlled trial protocol .
JOURNAL ARTICLE
Bhandari S, Pereira DIA, Chappell HF, Drakesmith H(2018). Intravenous Irons: From Basic Science to Clinical Practice . Pharmaceuticals (Basel, Switzerland).
Stelle I, Kalea AZ, Pereira DIA(2018). Iron deficiency anaemia: experiences and challenges . The Proceedings of the Nutrition Society.
Scheers, N. M., Pereira, D. I. A., Faria, N., Powell, J. J.(2018). Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells . Oncotarget. 9. (24). p. 17066-17077.
Stelle, I., Kalea, A. Z., Pereira, D. I. A.(2018). Iron deficiency anaemia: experiences and challenges . Proc Nutr Soc. p. 1-8.
Prentice AM, Mendoza YA, Pereira D, Cerami C, Wegmuller R, Constable A, Spieldenner J(2017). Dietary strategies for improving iron status: balancing safety and efficacy . Nutrition reviews.
Pereira, Dora, Prentice, Andrew M., Mendoza, Yenry A., Cerami, Carla, Wegmuller, Rita, Constable, Anne, Spieldenner, Jorg(2017). Dietary strategies for improving iron status: balancing safety and efficacy . Nutrition Reviews. 75. (1). p. 49-60.
Pereira, Dora, Wegmuller, Rita, Cerami, Carla, Prentice, Andrew(2017). PREDICTORS OF IRON ABSORPTION FROM A NOVEL NANO IRON SUPPLEMENT (IHAT) IN GAMBIAN WOMEN IN THE ABSENCE OF INFLAMMATION . American Journal of Hematology. 92. (8). p. E392.
Scheers, Nathalie, Pereira, Dora I. A., Faria, Nuno, Powell, Jonathan J. J.(2017). FERRIC CITRATE AND FERRIC EDTA DRIVE PROLIFERATION OF GUT EPITHELIAL CANCER CELLS VIA AMPHIREGULIN MEDIATED ACTIVATION OF THE MAP KINASE PATHWAY . American Journal of Hematology. 92. (8). p. E468.
Bellmann S, Carlander D, Fasano A, Momcilovic D, Scimeca JA, Waldman WJ, Gombau L, Tsytsikova L, Canady R, Pereira DI, et al.(2015). Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food-relevant nanomaterials . Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.
Pereira, Dora I. A., Aslam, Mohamad F., Frazer, David M., Schmidt, Annemarie, Walton, Gemma E., McCartney, Anne L., Gibson, Glenn R., Anderson, Greg J., Powell, Jonathan J.(2015). Dietary iron depletion at weaning imprints low microbiome diversity and this is not recovered with oral nano Fe(III) . Microbiologyopen. 4. (1). p. 12-27.
Bellmann, Susann, Carlander, David, Fasano, Alessio, Momcilovic, Dragan, Bellmann, Susann, Carlander, David, Fasano, Alessio, Momcilovic, Dragan, Scimeca, Joseph A., Waldman, W. James, et al.(2015). Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food-relevant nanomaterials . Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology. 7. (5). p. 609-622.
Tolkien, Zoe, Stecher, Lynne, Mander, Adrian P., Pereira, Dora I. A., Powell, Jonathan J.(2015). Ferrous Sulfate Supplementation Causes Significant Gastrointestinal Side-Effects in Adults: A Systematic Review and Meta-Analysis . Plos One. 10. (2).
Tolkien, Z., Stecher, L., Mander, A. P., Pereira, D. I. A., Powell, J. J.(2015). Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: a systematic review and meta-analysis. PLoS One. Accepted.
Pereira, D. I. A., Lederer, B., Powell, J. J.(2015). A balanced salt solution that prevents agglomeration of nano iron oxo-hydroxides in serum-free cellular assays . Materials Research Express. 2. p. 015403.
Pereira DI, Aslam MF, Frazer DM, Schmidt A, Walton GE, McCartney AL, Gibson GR, Anderson GJ, Powell JJ(2014). Dietary iron depletion at weaning imprints low microbiome diversity and this is not recovered with oral Nano Fe(III) . MicrobiologyOpen.
Latunde-Dada GO, Pereira DI, Tempest B, Ilyas H, Flynn AC, Aslam MF, Simpson RJ, Powell JJ(2014). A nanoparticulate ferritin-core mimetic is well taken up by HuTu 80 duodenal cells and its absorption in mice is regulated by body iron . The Journal of nutrition.
Pereira DI, Bruggraber SF, Faria N, Poots LK, Tagmount MA, Aslam MF, Frazer DM, Vulpe CD, Anderson GJ, Powell JJ(2014). Nanoparticulate iron(III) oxo-hydroxide delivers safe iron that is well absorbed and utilised in humans . Nanomedicine.
Aslam MF, Frazer DM, Faria N, Bruggraber SF, Wilkins SJ, Mirciov C, Powell JJ, Anderson GJ, Pereira DI(2014). Ferroportin mediates the intestinal absorption of iron from a nanoparticulate ferritin core mimetic in mice . FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
Powell JJ, Bruggraber SF, Faria N, Poots LK, Hondow N, Pennycook TJ, Latunde-Dada GO, Simpson RJ, Brown AP, Pereira DI(2014). A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity . Nanomedicine.
Pereira, Dora I. A., Bruggraber, Sylvaine F. A., Faria, Nuno, Poots, Lynsey K., Tagmount, Mani A., Aslam, Mohamad F., Frazer, David M., Vulpe, Chris D., Anderson, Gregory J., Powell, Jonathan J.(2014). Nanoparticulate iron(III) oxo-hydroxide delivers safe iron that is well absorbed and utilised in humans . Nanomedicine-Nanotechnology Biology and Medicine. 10. (8). p. 1877-1886.
Powell, Jonathan J., Bruggraber, Sylvaine F. A., Faria, Nuno, Poots, Lynsey K., Hondow, Nicole, Pennycook, Timothy J., Latunde-Dada, Gladys O., Simpson, Robert J., Brown, Andy P., Powell, Jonathan J., et al.(2014). A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity . Nanomedicine-Nanotechnology Biology and Medicine. 10. (7). p. 1529-1538.
Aslam, Mohamad F., Frazer, David M., Faria, Nuno, Bruggraber, Sylvaine F. A., Wilkins, Sarah J., Mirciov, Cornel, Powell, Jonathan J., Anderson, Greg J., Pereira, Dora I. A.(2014). Ferroportin mediates the intestinal absorption of iron from a nanoparticulate ferritin core mimetic in mice . Faseb Journal. 28. (8). p. 3671-3678.
Latunde-Dada, Gladys O., Pereira, Dora I. A., Tempest, Bethan, Ilyas, Hibah, Flynn, Angela C., Aslam, Mohamad F., Simpson, Robert J., Powell, Jonathan J.(2014). A Nanoparticulate Ferritin-Core Mimetic Is Well Taken Up by HuTu 80 Duodenal Cells and Its Absorption in Mice Is Regulated by Body Iron . Journal of Nutrition. 144. (12). p. 1896-1902.
Pereira, Dora I. A., Irving, Susana S. Couto, Lomer, Miranda C. E., Powell, Jonathan J.(2014). A rapid, simple questionnaire to assess gastrointestinal symptoms after oral ferrous sulphate supplementation . Bmc Gastroenterology. 14.
Aslam, M. F., Frazer, D. M., Faria, N., Bruggraber, S. F., Wilkins, S. J., Mirciov, C., Powell, J. J., Anderson, G. J., Pereira, D. I.(2014). Ferroportin mediates the intestinal absorption of iron from a nanoparticulate ferritin core mimetic in mice . Faseb Journal.
Pereira, Dora Ia, Couto Irving, Susana S., Lomer, Miranda Ce, Powell, Jonathan J.(2014). A rapid, simple questionnaire to assess gastrointestinal symptoms after oral ferrous sulphate supplementation . BMC gastroenterology. 14. (1). p. 103.
Powell, J. J., Bruggraber, S. F., Faria, N., Poots, L. K., Hondow, N., Pennycook, T. J., Latunde-Dada, G. O., Simpson, R. J., Brown, A. P., Pereira, D. I.(2014). A nano-disperse ferritin-core mimetic that efficiently corrects anaemia without luminal iron redox activity . Nanomedicine: Nanotechnology, Biology and Medicine.
Tolkien Z, Pereira DI, Prassmayer L, Fitt E, Pot G, Greenfield SM, Powell JJ(2013). Dietary iron does not impact the quality of life of patients with quiescent ulcerative colitis: an observational study . Nutrition journal.
Pereira DI, Mergler BI, Faria N, Bruggraber SF, Aslam MF, Poots LK, Prassmayer L, Lönnerdal B, Brown AP, Powell JJ(2013). Caco-2 cell acquisition of dietary iron(III) invokes a nanoparticulate endocytic pathway . PloS one.
Powell JJ, Cook WB, Chatfield M, Hutchinson C, Pereira DIa, Lomer MC(2013). Iron status is inversely associated with dietary iron intakes in patients with inactive or mildly active inflammatory bowel disease . Nutrition & metabolism.
Powell JJ, Cook WB, Hutchinson C, Tolkien Z, Chatfield M, Pereira DIa, Lomer MC(2013). Dietary fortificant iron intake is negatively associated with quality of life in patients with mildly active inflammatory bowel disease . Nutrition & metabolism.
Luo, X. M., Tempest, B., Aslam, M., Pereira, D., Powell, J., Latunde-Dada, Y.(2013). Studies on in Vitro Iron Availability from Ligand-Modified Nano Fe(Iii) Oxo-Hydroxide Compounds in Cultured Human Cells . American Journal of Hematology. 88. (5). p. E84.
Pereira, Dora I. A., Mergler, Bianca I., Faria, Nuno, Bruggraber, Sylvaine F. A., Aslam, Mohamad F., Poots, Lynsey K., Prassmayer, Laura, Loennerdal, Bo, Brown, Andy P., Powell, Jonathan J.(2013). Caco-2 Cell Acquisition of Dietary Iron(III) Invokes a Nanoparticulate Endocytic Pathway . Plos One. 8. (11).
Aslam, M., Pereira, D., Frazer, D., Faria, N., Bruggraber, S., Powell, J., Anderson, G.(2013). The Absorption of Nanoparticulate Iron Hydroxide Is Ferroportin-Mediated . American Journal of Hematology. 88. (5). p. E191.
Tolkien, Zoe, Pereira, Dora I. A., Prassmayer, Laura, Fitt, Emily, Pot, Gerda, Greenfield, Simon M., Powell, Jonathan J.(2013). Dietary iron does not impact the quality of life of patients with quiescent ulcerative colitis: an observational study . Nutrition Journal. 12.
Gerloff, Kirsten, Pereira, Dora I. A., Faria, Nuno, Boots, Agnes W., Kolling, Julia, Foerster, Irmgard, Albrecht, Catrin, Powell, Jonathan J., Schins, Roel P. F.(2013). Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells . Nanotoxicology. 7. (4). p. 353-366.
Powell, Jonathan J., Cook, William B., Chatfield, Mark, Hutchinson, Carol, Pereira, Dora I. A., Lomer, Miranda C. E.(2013). Iron status is inversely associated with dietary iron intakes in patients with inactive or mildly active inflammatory bowel disease . Nutrition & Metabolism. 10.
Powell, Jonathan J., Cook, William B., Hutchinson, Carol, Tolkien, Zoe, Chatfield, Mark, Pereira, Dora I. A., Lomer, Miranda C. E., Powell, Jonathan J., Cook, William B., Hutchinson, Carol, et al.(2013). Dietary fortificant iron intake is negatively associated with quality of life in patients with mildly active inflammatory bowel disease . Nutrition & Metabolism. 10.
Aslam, M., Pereira, D., Frazer, D., Faria, N., Bruggraber, S., Powell, J., Anderson, G.(2013). The Absorption of Nanoparticulate Iron Hydroxide Is Ferroportin-Mediated. American Journal of Hematology. 88. (5). p. E191.
Luo, X. M., Tempest, B., Aslam, M., Pereira, D., Powell, J., Latunde-Dada, Y.(2013). Studies on in Vitro Iron Availability from Ligand-Modified Nano Fe(Iii) Oxo-Hydroxide Compounds in Cultured Human Cells. American Journal of Hematology. 88. (5). p. E84.
Gerloff K, Pereira DI, Faria N, Boots AW, Kolling J, Förster I, Albrecht C, Powell JJ, Schins RP(2012). Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells . Nanotoxicology.
Mergler, B.I., Roth, E., Bruggraber, S.F.A., Powell, J.J., Pereira, D.I.A.(2012). Development of the Caco-2 Model for Assessment of Iron Absorption and Utilisation at Supplemental Levels . Journal of Pharmacy and Nutrition Sciences. 2. (1). p. 27-34.
Liu WL, Liu W, Liu CM, Yang SB, Liu JH, Zheng HJ, Su KM(2011). Medium-chain fatty acid nanoliposomes suppress body fat accumulation in mice . The British journal of nutrition.
Pereira, D.I.A.(2011). Medium-chain fatty acid nanoliposomes suppress body fat accumulation in mice . British Journal of Nutrition. 106. (9). p. 1319-1320.
Faria, N. and Pereira, D. and Mergler, B. and Powell, J.(2011). Ligand doping of iron oxide nanoparticles as an approach to novel oral iron therapeutics . Proceedings of the IEEE Conference on Nanotechnology. p. 837-840.
Faria, N. and Winship, P.D. and Weiss, D.J. and Coles, B.J. and Schoenberg, R. and Hutchison, C. and Pereira, D.I.A. and Powell, J.J.(2011). Development of DRC-ICP-MS methodology for the rapid determination of 58Fe erythrocyte incorporation in human iron absorption studies . Journal of Analytical Atomic Spectrometry. 26. (8). p. 1648-1652.
Mergler, B., Faria, N., Bruggraber, S., Powell, J., Pereira, D., Mergler, B., Faria, N., Bruggraber, S., Powell, J., Pereira, D.(2011). Intestinal absorption of nano iron: Cellular uptake mechanism(s) in Caco-2 cells. Ann Nutr Metab. 58. p. 8.
Faria, Nuno, Winship, Peter David, Weiss, Dominik Jacob, Coles, Barry James, Schoenberg, Ronny, Hutchison, Carol, Pereira, Dora Isabel Amaral, Powell, Jonathan Joseph(2011). Development of DRC-ICP-MS methodology for the rapid determination of Fe-58 erythrocyte incorporation in human iron absorption studies . Journal of Analytical Atomic Spectrometry. 26. (8). p. 1648-1652.
Mergler, B., Faria, N., Bruggraber, S., Powell, J., Pereira, D.(2011). Intestinal absorption of nano iron: Cellular uptake mechanism(s) in Caco-2 cells . Ann Nutr Metab. 58. p. 8.
Tolkien, Z., Powell, J., Pereira, D.(2011). Dietary iron and quality of life in inflammatory bowel disease . Ann Nutr Metab. 58. p. 88.
Pereira, Dora I. A.(2011). Medium-chain fatty acid nanoliposomes suppress body fat accumulation in mice . British Journal of Nutrition. 106. (9). p. 1319-1320.
Gerloff, K., Pereira, D., Faria, N., Forster, I., Albrecht, C., Powell, J. J., Schins, R. P. F.(2010). Simulated gastric conditions do not influence nanoparticle-induced effects on cytotoxicity and interleukin-8 release from human intestinal cells. Naunyn-Schmiedebergs Archives of Pharmacology. 381. p. 69.
Gerloff, K., Pereira, D., Faria, N., Forster, I., Albrecht, C., Powell, J. J., Schins, R. P. F.(2010). Simulated gastric conditions do not influence nanoparticle-induced effects on cytotoxicity and interleukin-8 release from human intestinal cells . Naunyn-Schmiedebergs Archives of Pharmacology. 381. p. 69.
Hutchinson, C., Collard, K., Bruggraber, S., Pereira, D., Powell, J.(2009). PLASMA ASCORBATE AND MALONYLDIALDEHYDE AFTER INGESTION OF FERROUS SULFATE . Annals of Nutrition and Metabolism. 55. p. 197.
Pereira, Dora, Hutchinson, Carol, Collard, Keith, Bruggraber, Sylvaine, Powell, Jonathan(2009). PLASMA ASCORBATE AND MALONYLDIALDEHYDE AFTER INGESTION OF FERROUS SULFATE. Annals of Nutrition and Metabolism. 55. p. 197.
Faria, N., Winship, P., Pereira, D., Powell, J. J., Collery, P, Maymard, I, Theophanides, T, Khassanova, L, Collery, T(2008). The use of DRC-ICP-MS to determine isotopic enrichment in iron absorption studies . Metal Ions in Biology and Medicine, Vol 10. 10. p. 873-877.
Faria, N., Winship, P., Pereira, D., Powell, J. J., Collery, P, Maymard, I, Theophanides, T, Khassanova, L, Collery, T(2008). The use of DRC-ICP-MS to determine isotopic enrichment in iron absorption studies. Metal Ions in Biology and Medicine, Vol 10. 10. p. 873-877.
Pereira, D. I. A., McCartney, A. L., Gibson, G. R.(2003). An in vitro study of the probiotic potential of a bile-salt-hydrolyzing Lactobacillus fermentum strain, and determination of its cholesterol-lowering properties . Applied and Environmental Microbiology. 69. (8). p. 4743-4752.
Pereira, D. I. A., Gibson, G. R.(2002). Cholesterol assimilation by lactic acid bacteria and bifidobacteria isolated from the human gut . Applied and Environmental Microbiology. 68. (9). p. 4689-4693.
Pereira, D. I. A., Gibson, G. R.(2002). Effects of consumption of probiotics and prebiotics on serum lipid levels in humans . Critical Reviews in Biochemistry and Molecular Biology. 37. (4). p. 259-+.
Neves, A. A., Pereira, D. A., Vieira, L. M., Menezes, J. C.(2000). Real time monitoring biomass concentration in Streptomyces clavuligerus cultivations with industrial media using a capacitance probe . Journal of Biotechnology. 84. (1). p. 45-52.
Nollet, Lode J.A., Pereira, Dora I., Verstraete, Willy(1999). Effect of a probiotic bile salt hydrolytic Lactobacillus reuteri on the human gastrointestinal microbiota as simulated in the SHIME reactor system . Microbial Ecology in Health and Disease. 11. (1). p. 13-21.
Maricou, H., Pereira, D., Verschuere, L., Philips, S., Verstraete, W.(1998). Measurements of some volatile compounds by means of the electronic nose . Water Air and Soil Pollution. 107. (1-4). p. 423-442.
BOOK CHAPTER
Tolkien, Z., Powell, J. J., Periera, D. I. A.(2011). Dietary iron and quality of life in inflammatory bowel disease. Metal Ions in Biology and Medicine, vol 11. p. 103.
Mergler, B. I., Faria, N. J. R., Bruggraber, S. F. A., Powell, J. J, Pereira, D. A.(2011). Intestinal absorption of nano iron: cellular uptake mechanism(s) in Caco-2 cells. Metal Ions in Biology and Medicine, vol 11. p. 50.
Kopanska, K., Pereira, D. A., Bruggraber, S. F. A., Charalambos, C., Powell, J. J.(2008). The influence of manganese supplementation on blood manganese levels and leucocyte expression or activity of manganese-dependent enzymes . Metal Ions in Biology and Medicine, Vol 10. 10. p. 848-854.
Pereira, D. A., Mergler, B., Pereira, D. A., Mergler, B., Faria, N., Parracho, H., Powell, J. J.(2008). An in vitro model for assessing the gastrointestinal dissolution properties of iron: effect of organic acids and bile acids . Metal Ions in Biology and Medicine, Vol 10. 10. p. 878-882.
Pereira, D. A., Mergler, B., Faria, N., Parracho, H., Powell, J. J.(2008). An in vitro model for assessing the gastrointestinal dissolution properties of iron: effect of organic acids and bile acids. Metal Ions in Biology and Medicine, Vol 10. 10. p. 878-882.
Kopanska, K., Pereira, D. A., Bruggraber, S. F. A., Charalambos, C., Powell, J. J.(2008). The influence of manganese supplementation on blood manganese levels and leucocyte expression or activity of manganese-dependent enzymes. Metal Ions in Biology and Medicine, Vol 10. 10. p. 848-854.